{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:07:27Z","timestamp":1790352447985,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.jchf.2016.12.020","type":"journal-article","created":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T06:30:22Z","timestamp":1488263422000},"page":"182-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Left Ventricular Function Across the Spectrum of Body Mass Index in African\u00a0Americans"],"prefix":"10.1016","volume":"5","author":[{"given":"Vivek G.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak K.","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Terry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmond K.","family":"Kabagambe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldolfo","family":"Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Griswold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Jeffrey","family":"Carr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchf.2016.12.020_bib1","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1161\/CIR.0000000000000350","article-title":"Heart disease and stroke statistics\u20142016 update: a report from the American Heart Association","volume":"133","author":"Mozaffarian","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib2","first-page":"600","article-title":"Obesity, subclinical myocardial injury, and incident heart failure","volume":"2","author":"Ndumele","year":"2014","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2016.12.020_bib3","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.jacc.2010.10.042","article-title":"Effect of obesity and overweight on left ventricular diastolic function: a community-based study in an elderly cohort","volume":"57","author":"Russo","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2016.12.020_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/CRD.0b013e3181f877d2","article-title":"Effects of obesity and subsequent weight reduction on left ventricular function","volume":"19","author":"Lakhani","year":"2011","journal-title":"Cardiology in review"},{"key":"10.1016\/j.jchf.2016.12.020_bib5","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1038\/oby.2007.241","article-title":"Impact of obesity on left ventricular mass and function in subjects with chronic volume overload","volume":"15","author":"Ballo","year":"2007","journal-title":"Obesity"},{"key":"10.1016\/j.jchf.2016.12.020_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00000441-200104000-00003","article-title":"Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome","volume":"321","author":"Alpert","year":"2001","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.jchf.2016.12.020_bib7","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1161\/01.CIR.0000147184.13872.0F","article-title":"Alterations of left ventricular myocardial characteristics associated with obesity","volume":"110","author":"Wong","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib8","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1161\/CIRCULATIONAHA.107.754424","article-title":"Cardiac mechanics revisited: the relationship of cardiac architecture to ventricular function","volume":"118","author":"Buckberg","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib9","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1136\/heart.89.10.1152","article-title":"Effects of isolated obesity on systolic and diastolic left ventricular function","volume":"89","author":"Pascual","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.jchf.2016.12.020_bib10","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1093\/oxfordjournals.eurheartj.a060249","article-title":"Left ventricular diastolic and systolic function in normotensive obese subjects: influence of degree and duration of obesity","volume":"13","author":"Scaglione","year":"1992","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2016.12.020_bib11","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1148\/rg.325115098","article-title":"Myocardial tagging with MR imaging: overview of normal and pathologic findings","volume":"32","author":"Jeung","year":"2012","journal-title":"Radiographics"},{"key":"10.1016\/j.jchf.2016.12.020_bib12","first-page":"S6","article-title":"Toward resolution of cardiovascular health disparities in African Americans: design and methods of the Jackson Heart Study","volume":"15","author":"Taylor","year":"2005","journal-title":"Ethn Dis"},{"key":"10.1016\/j.jchf.2016.12.020_bib13","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1016\/j.jacc.2005.12.075","article-title":"Subclinical atherosclerosis and incipient regional myocardial dysfunction in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis (MESA)","volume":"47","author":"Fernandes","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2016.12.020_bib14","first-page":"500","article-title":"Association of obesity in early adulthood and middle age with incipient left ventricular dysfunction and structural remodeling: the CARDIA study (Coronary Artery Risk Development in Young Adults)","volume":"2","author":"Kishi","year":"2014","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2016.12.020_bib15","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1161\/01.ATV.0000194077.23234.ae","article-title":"Coronary artery atherosclerosis is related to reduced regional left ventricular function in individuals without history of clinical cardiovascular disease: the Multiethnic Study of Atherosclerosis","volume":"26","author":"Edvardsen","year":"2006","journal-title":"Arteriosclerosis, thrombosis, and vascular biology"},{"key":"10.1016\/j.jchf.2016.12.020_bib16","article-title":"Recruiting African-American research participation in the Jackson Heart Study: methods, response rates, and sample description","volume":"15","author":"Fuqua","year":"2005","journal-title":"Ethn Dis"},{"key":"10.1016\/j.jchf.2016.12.020_bib17","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1001\/jama.2012.3954","article-title":"Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate","volume":"307","author":"Matsushita","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jchf.2016.12.020_bib18","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.ajo.2015.03.008","article-title":"P-selectin plasma levels and genetic variant associated with diabetic retinopathy in African Americans","volume":"159","author":"Penman","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jchf.2016.12.020_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2369-11-1","article-title":"The relation of C-reactive protein to chronic kidney disease in African Americans: the Jackson Heart Study","volume":"11","author":"Fox","year":"2010","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.jchf.2016.12.020_bib20","doi-asserted-by":"crossref","first-page":"5419","DOI":"10.1210\/jc.2010-1378","article-title":"Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study","volume":"95","author":"Liu","year":"2010","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.jchf.2016.12.020_bib21","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1042\/CS20030153","article-title":"Relationship between longitudinal and radial contractility in subclinical diabetic heart disease","volume":"106","author":"Fang","year":"2004","journal-title":"Clin Sci"},{"key":"10.1016\/j.jchf.2016.12.020_bib22","first-page":"345","article-title":"Quantification of regional myocardial wall motion by cardiovascular magnetic resonance","volume":"4","author":"Jiang","year":"2014","journal-title":"Quant Imaging Med Surg"},{"key":"10.1016\/j.jchf.2016.12.020_bib23","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1161\/CIRCULATIONAHA.112.093146","article-title":"Age, sex, and hypertension-related remodeling influences left ventricular torsion assessed by tagged cardiac magnetic resonance in asymptomatic individuals: the multi-ethnic study of atherosclerosis","volume":"126","author":"Yoneyama","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib24","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1161\/01.CIR.0000127959.28627.F8","article-title":"Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women","volume":"109","author":"Peterson","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib25","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.amjcard.2004.06.076","article-title":"Tissue Doppler imaging of the right and left ventricle in severe obesity (body mass index >35 kg\/m2)","volume":"94","author":"Willens","year":"2004","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2016.12.020_bib26","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.echo.2006.03.033","article-title":"Obesity cardiomyopathy: is it a reality? An ultrasonic tissue characterization study","volume":"19","author":"Di Bello","year":"2006","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jchf.2016.12.020_bib27","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/oby.2002.104","article-title":"Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity","volume":"10","author":"Iacobellis","year":"2002","journal-title":"Obes Res"},{"key":"10.1016\/j.jchf.2016.12.020_bib28","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1540-8175.2011.01410.x","article-title":"Left ventricular function in hypertension: new insight by speckle tracking echocardiography","volume":"28","author":"Imbalzano","year":"2011","journal-title":"Echocardiography"},{"key":"10.1016\/j.jchf.2016.12.020_bib29","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.echo.2008.07.016","volume":"21","author":"Mizuguchi","year":"2008","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jchf.2016.12.020_bib30","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1093\/eurheartj\/ehs124","article-title":"Phenotypic and pathophysiological heterogeneity in heart failure with preserved ejection fraction","volume":"33","author":"Shah","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2016.12.020_bib31","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1161\/CIRCULATIONAHA.104.481465","article-title":"Contractile behavior of the left ventricle in diastolic heart failure: with emphasis on regional systolic function","volume":"113","author":"Aurigemma","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib32","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1161\/01.CIR.0000021240.86593.9D","article-title":"Evolution of the study of left ventricular function: everything old is new again","volume":"105","author":"Carabello","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib33","doi-asserted-by":"crossref","first-page":"E937","DOI":"10.1152\/ajpendo.00061.2012","article-title":"Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease","volume":"303","author":"Cherian","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jchf.2016.12.020_bib34","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/cvr\/cvu045","article-title":"Epicardial adipose tissue and atrial fibrillation","volume":"102","author":"Hatem","year":"2014","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jchf.2016.12.020_bib35","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/1479-5876-10-145","article-title":"Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice","volume":"10","author":"Wang","year":"2012","journal-title":"J\u00a0Transl Med"},{"key":"10.1016\/j.jchf.2016.12.020_bib36","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1161\/CIRCULATIONAHA.111.069518","article-title":"Effects of catecholamine stress on diastolic function and myocardial energetics in obesity","volume":"125","author":"Rider","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2016.12.020_bib37","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.2337\/diabetes.54.12.3530","article-title":"Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL\/6 mice","volume":"54","author":"Park","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.jchf.2016.12.020_bib38","doi-asserted-by":"crossref","first-page":"e86447","DOI":"10.1371\/journal.pone.0086447","article-title":"AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity","volume":"9","author":"Oliveira-Junior","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jchf.2016.12.020_bib39","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.bbalip.2005.03.005","article-title":"Fatty acid metabolism is enhanced in type 2 diabetic hearts","volume":"1734","author":"Carley","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jchf.2016.12.020_bib40","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/cvr\/cvt216","article-title":"Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation","volume":"101","author":"Masoud","year":"2014","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jchf.2016.12.020_bib41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12933-015-0310-4","article-title":"Visceral adiposity is associated with altered myocardial glucose uptake measured by (18)FDG-PET in 346 subjects with normal glucose tolerance, prediabetes, and type 2 diabetes","volume":"14","author":"Kim","year":"2015","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.jchf.2016.12.020_bib42","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/meta.2001.21693","article-title":"Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity","volume":"50","author":"Smith","year":"2001","journal-title":"Metabolism"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177917300756?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177917300756?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T00:30:20Z","timestamp":1536021020000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177917300756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S2213177917300756"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2016.12.020","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left Ventricular Function Across the Spectrum of Body Mass Index in African\u00a0Americans","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2016.12.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}