{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T06:52:19Z","timestamp":1781074339631,"version":"3.54.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HHSN268200425207C"],"award-info":[{"award-number":["HHSN268200425207C"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000769","name":"Oxford University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jchf.2017.08.018","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T10:16:41Z","timestamp":1507889801000},"page":"782-791","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction"],"prefix":"10.1016","volume":"5","author":[{"given":"Ali","family":"Vazir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Claggett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertram","family":"Pitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inder","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Sweitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Fleg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Rouleau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjiv","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc A.","family":"Pfeffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott D.","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchf.2017.08.018_bib1","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1016\/j.jacc.2011.12.044","article-title":"Association of heart rate and outcomes in a broad spectrum of patients with chronic heart failure: results from the CHARM (Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity) program","volume":"59","author":"Castagno","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2017.08.018_bib2","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/S0140-6736(10)61259-7","article-title":"Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial","volume":"376","author":"Bohm","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jchf.2017.08.018_bib3","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.jacc.2007.04.079","article-title":"Resting heart rate in cardiovascular disease","volume":"50","author":"Fox","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2017.08.018_bib4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/heart.89.1.42","article-title":"Mode of death in heart failure: findings from the ATLAS trial","volume":"89","author":"Poole-Wilson","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.jchf.2017.08.018_bib5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1081\/CEH-200031959","article-title":"Elevated heart rate: a major risk factor for cardiovascular disease","volume":"26","author":"Palatini","year":"2004","journal-title":"Clin Exp Hypertens"},{"key":"10.1016\/j.jchf.2017.08.018_bib6","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1001\/jama.2011.1826","article-title":"Temporal changes in resting heart rate and deaths from ischemic heart disease","volume":"306","author":"Nauman","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.jchf.2017.08.018_bib7","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.amjcard.2008.08.071","article-title":"Relation of heart rate at rest and long-term (>20 years) death rate in initially healthy middle-aged men","volume":"103","author":"Jouven","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2017.08.018_bib8","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1161\/HYPERTENSIONAHA.109.144808","article-title":"Resting heart rate pattern during follow-up and mortality in hypertensive patients","volume":"55","author":"Paul","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.jchf.2017.08.018_bib9","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/eurheartj\/ehu401","article-title":"Prognostic importance of temporal changes in resting heart rate in heart failure patients: an analysis of the CHARM program","volume":"36","author":"Vazir","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2017.08.018_bib10","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1056\/NEJMoa1313731","article-title":"Spironolactone for heart failure with preserved ejection fraction","volume":"370","author":"Pitt","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2017.08.018_bib11","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/CIRCHEARTFAILURE.112.972794","article-title":"Baseline characteristics of patients in the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial","volume":"6","author":"Shah","year":"2013","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2017.08.018_bib12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1161\/CIRCULATIONAHA.114.013255","article-title":"Regional variation in patients and outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) trial","volume":"131","author":"Pfeffer","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2017.08.018_bib13","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.ahj.2015.05.008","article-title":"Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus","volume":"170","author":"Lewis","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2017.08.018_bib14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/biomet\/69.1.239","article-title":"Partial residuals for the proportional hazards regression model","volume":"69","author":"Schoenfeld","year":"1982","journal-title":"Biometrika"},{"key":"10.1016\/j.jchf.2017.08.018_bib15","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/0735-1097(94)90738-2","article-title":"Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure","volume":"23","author":"Kaye","year":"1994","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177917306029?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177917306029?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T18:52:22Z","timestamp":1658256742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177917306029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S2213177917306029"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2017.08.018","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2017.08.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}