{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T07:44:53Z","timestamp":1788335093111,"version":"build-2803163510"},"reference-count":70,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.jchf.2019.01.011","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T16:51:31Z","timestamp":1551113491000},"page":"181-191","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Primary Prevention of Heart Failure in\u00a0Women"],"prefix":"10.1016","volume":"7","author":[{"given":"Melissa A.","family":"Daubert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela S.","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchf.2019.01.011_bib1","doi-asserted-by":"crossref","first-page":"e146","DOI":"10.1161\/CIR.0000000000000485","article-title":"Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association","volume":"135","author":"Benjamin","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib2","series-title":"Incidence and Prevalence: 2006 Chart Book on Cardiovascular and Lung Diseases","year":"2006"},{"key":"10.1016\/j.jchf.2019.01.011_bib3","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1093\/eurjhf\/hft115","article-title":"Sex-specific acute heart failure phenotypes and outcomes from PROTECT","volume":"15","author":"Meyer","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib4","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1093\/eurheartj\/eht152","article-title":"Neurohormonal and clinical sex differences in heart failure","volume":"34","author":"Meyer","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2019.01.011_bib5","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1161\/01.CIR.0000141726.01302.83","article-title":"Predictors of heart failure among women with coronary disease","volume":"110","author":"Bibbins-Domingo","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib6","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.amjmed.2009.04.022","article-title":"Risk factors for heart failure: a population-based case-control study","volume":"122","author":"Dunlay","year":"2009","journal-title":"Am J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib7","doi-asserted-by":"crossref","first-page":"e002883","DOI":"10.1161\/CIRCHEARTFAILURE.115.002883","article-title":"Risk factors for incident hospitalized heart failure with preserved versus reduced ejection fraction in a multiracial cohort of postmenopausal women","volume":"9","author":"Eaton","year":"2016","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib8","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s00392-014-0788-x","article-title":"Sex differences in new-onset heart failure","volume":"104","author":"Meyer","year":"2015","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1161\/CIRCHEARTFAILURE.112.972828","article-title":"Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction","volume":"6","author":"Ho","year":"2013","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib10","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1161\/CIRCULATIONAHA.108.815944","article-title":"Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the Framingham Heart Study of the National Heart, Lung, and Blood Institute","volume":"119","author":"Lee","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib11","doi-asserted-by":"crossref","first-page":"e004642","DOI":"10.1161\/CIRCHEARTFAILURE.117.004642","article-title":"Risk factor burden, heart failure, and survival in women of different ethnic groups: insights from the Women's Health Initiative","volume":"11","author":"Breathett","year":"2018","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib12","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1056\/NEJMra021498","article-title":"Heart failure","volume":"348","author":"Jessup","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib13","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2008.11.013","volume":"53","author":"Hunt","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib14","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1161\/CIR.0b013e31829e8807","article-title":"2013 ACCF\/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on practice guidelines","volume":"128","author":"Yancy","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib15","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1161\/CIR.0b013e31820faaf8","article-title":"Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the American Heart Association","volume":"123","author":"Mosca","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib16","doi-asserted-by":"crossref","first-page":"e004437","DOI":"10.1161\/CIRCOUTCOMES.117.004437","article-title":"Sex Differences in ischemic heart disease: advances, obstacles, and next steps","volume":"11","author":"Aggarwal","year":"2018","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.jchf.2019.01.011_bib17","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11883-018-0750-x","article-title":"Gender differences in ischemic cardiomyopathy","volume":"20","author":"Divoky","year":"2018","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.jchf.2019.01.011_bib18","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jacc.2018.02.033","article-title":"Hypertension across a woman's life cycle","volume":"71","author":"Wenger","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib19","first-page":"e28","article-title":"Heart disease and stroke statistics--2014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib20","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/ajh.2008.185","article-title":"Gender differences in hypertension treatment, drug utilization patterns, and blood pressure control among US adults with hypertension: data from the National Health and Nutrition Examination Survey 1999-2004","volume":"21","author":"Gu","year":"2008","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jchf.2019.01.011_bib21","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s12265-013-9514-8","article-title":"Should there be sex-specific criteria for the diagnosis and treatment of heart failure?","volume":"7","author":"Greiten","year":"2014","journal-title":"J\u00a0Cardiovasc Transl Res"},{"key":"10.1016\/j.jchf.2019.01.011_bib22","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/hr.2011.189","article-title":"Sex-related differences in pharmacokinetics and pharmacodynamics of anti-hypertensive drugs","volume":"35","author":"Ueno","year":"2012","journal-title":"Hypertens Res"},{"key":"10.1016\/j.jchf.2019.01.011_bib23","doi-asserted-by":"crossref","first-page":"e003613","DOI":"10.1161\/CIRCHEARTFAILURE.116.003613","article-title":"Effect of intensive blood pressure treatment on heart failure events in the Systolic Blood Pressure Reduction Intervention Trial","volume":"10","author":"Upadhya","year":"2017","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib24","doi-asserted-by":"crossref","first-page":"830","DOI":"10.2337\/dc13-1755","article-title":"Sex differences in diabetes and risk of incident coronary artery disease in healthy young and middle-aged adults","volume":"37","author":"Kalyani","year":"2014","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jchf.2019.01.011_bib25","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/eurheartj\/ehv134","article-title":"Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes","volume":"36","author":"Seferovic","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2019.01.011_bib26","doi-asserted-by":"crossref","first-page":"514","DOI":"10.2337\/diacare.28.3.514","article-title":"Sex disparities in treatment of cardiac risk factors in patients with type 2 diabetes","volume":"28","author":"Wexler","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jchf.2019.01.011_bib27","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1056\/NEJMoa1812389","article-title":"Dapagliflozin and cardiovascular outcomes in type 2 diabetes","volume":"380","author":"Wiviott","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib28","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1056\/NEJMoa1504720","article-title":"Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes","volume":"373","author":"Zinman","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib29","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1056\/NEJMoa1611925","article-title":"Canagliflozin and cardiovascular and renal events in type 2 diabetes","volume":"377","author":"Neal","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib30","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/eurjhf\/hft025","article-title":"Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study","volume":"15","author":"Kraigher-Krainer","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib31","first-page":"983","article-title":"Physical activity and incidence of heart failure in postmenopausal women","volume":"6","author":"LaMonte","year":"2018","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2019.01.011_bib32","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","article-title":"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study","volume":"364","author":"Yusuf","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jchf.2019.01.011_bib33","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.amjmed.2015.03.027","article-title":"American Heart Association's life's simple 7: avoiding heart failure and preserving cardiac structure and function","volume":"128","author":"Folsom","year":"2015","journal-title":"Am J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib34","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1161\/CIRCULATIONAHA.111.044784","article-title":"Associations of pregnancy complications with calculated cardiovascular disease risk and cardiovascular risk factors in middle age: the Avon Longitudinal Study of Parents and Children","volume":"125","author":"Fraser","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib35","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","article-title":"Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis","volume":"335","author":"Bellamy","year":"2007","journal-title":"BMJ"},{"key":"10.1016\/j.jchf.2019.01.011_bib36","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ahj.2008.06.042","article-title":"Cardiovascular sequelae of preeclampsia\/eclampsia: a systematic review and meta-analyses","volume":"156","author":"McDonald","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2019.01.011_bib37","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1161\/CIRCULATIONAHA.112.128751","article-title":"Elevated blood pressure in pregnancy and subsequent chronic disease risk","volume":"127","author":"Mannisto","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib38","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.cpcardiol.2012.07.003","article-title":"Sex and gender differences in myocarditis and dilated cardiomyopathy","volume":"38","author":"Fairweather","year":"2013","journal-title":"Curr Probl Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib39","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/nrcardio.2009.105","article-title":"Gender differences in the cardiovascular effect of sex hormones","volume":"6","author":"Vitale","year":"2009","journal-title":"Nature Rev Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib40","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1001\/jama.288.1.49","article-title":"Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen\/Progestin Replacement Study follow-up (HERS II)","volume":"288","author":"Grady","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jchf.2019.01.011_bib41","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","article-title":"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial","volume":"288","author":"Rossouw","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jchf.2019.01.011_bib42","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1097\/CCM.0000000000000851","article-title":"Stress-induced cardiomyopathy","volume":"43","author":"Boland","year":"2015","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib43","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.jacc.2018.07.072","article-title":"Stress cardiomyopathy diagnosis and treatment: JACC State-of-the-Art Review","volume":"72","author":"Medina de Chazal","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib44","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1097\/gme.0b013e3182517bd0","article-title":"Early menopause predicts future coronary heart disease and stroke: the Multi-Ethnic Study of Atherosclerosis","volume":"19","author":"Wellons","year":"2012","journal-title":"Menopause"},{"key":"10.1016\/j.jchf.2019.01.011_bib45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.ijcard.2016.03.196","article-title":"Drug treatment rates with beta-blockers and ACE-inhibitors\/angiotensin receptor blockers and recurrences in takotsubo cardiomyopathy: a meta-regression analysis","volume":"214","author":"Brunetti","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib46","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/clc.22280","article-title":"Lack of efficacy of drug therapy in preventing takotsubo cardiomyopathy recurrence: a meta-analysis","volume":"37","author":"Santoro","year":"2014","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib47","first-page":"409","article-title":"Characteristics, adverse events, and racial differences among delivering mothers with peripartum cardiomyopathy","volume":"1","author":"Kao","year":"2013","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2019.01.011_bib48","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1016\/j.jacc.2018.02.049","article-title":"Carvedilol for prevention of chemotherapy-related cardiotoxicity: the CECCY trial","volume":"71","author":"Avila","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib49","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1093\/eurheartj\/ehw022","article-title":"Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 x 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol","volume":"37","author":"Gulati","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2019.01.011_bib50","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ahj.2017.03.010","article-title":"Lisinopril or Coreg CR in reducing cardiotoxicity in women with breast cancer receiving trastuzumab: a rationale and design of a randomized clinical trial","volume":"188","author":"Guglin","year":"2017","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2019.01.011_bib51","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1001\/jamacardio.2018.2559","article-title":"Enrollment of older patients, women, and racial and ethnic minorities in contemporary heart failure clinical trials: a systematic review","volume":"3","author":"Tahhan","year":"2018","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib52","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1056\/NEJM199209033271003","article-title":"Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions","volume":"327","author":"Investigators","year":"1992","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib53","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/S0735-1097(98)00675-5","article-title":"Beta-adrenergic blocking agent use and mortality in patients with asymptomatic and symptomatic left ventricular systolic dysfunction: a post hoc analysis of the Studies of Left Ventricular Dysfunction","volume":"33","author":"Exner","year":"1999","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib55","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1056\/NEJMoa052256","article-title":"Trends in prevalence and outcome of heart failure with preserved ejection fraction","volume":"355","author":"Owan","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2019.01.011_bib56","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0002-9149(00)01393-X","article-title":"Importance of heart failure with preserved systolic function in patients > or\u00a0= 65 years of age. CHS Research Group. Cardiovascular Health Study","volume":"87","author":"Kitzman","year":"2001","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib57","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1161\/CIRCHEARTFAILURE.112.970061","article-title":"Sex differences in clinical characteristics and outcomes in elderly patients with heart failure and preserved ejection fraction: the Irbesartan in Heart Failure with Preserved Ejection Fraction (I-PRESERVE) trial","volume":"5","author":"Lam","year":"2012","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib58","first-page":"701","article-title":"The association of obesity and cardiometabolic traits with incident HFpEF and HFrEF","volume":"6","author":"Savji","year":"2018","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2019.01.011_bib59","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jacc.2013.02.092","article-title":"A\u00a0novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation","volume":"62","author":"Paulus","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib60","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1161\/CIRCULATIONAHA.116.021884","article-title":"Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap","volume":"134","author":"Shah","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib61","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1016\/j.jacc.2013.11.004","article-title":"2013 AHA\/ACC\/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and The Obesity Society","volume":"63","author":"Jensen","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2019.01.011_bib62","first-page":"633","article-title":"Obesity-related heart failure with a preserved ejection fraction: the mechanistic rationale for combining inhibitors of aldosterone, neprilysin, and sodium-glucose cotransporter-2","volume":"6","author":"Packer","year":"2018","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2019.01.011_bib63","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1210\/js.2017-00020","article-title":"Effects of rapid weight loss on systemic and adipose tissue inflammation and metabolism in obese postmenopausal women","volume":"1","author":"Aleman","year":"2017","journal-title":"J\u00a0Endocr Soc"},{"key":"10.1016\/j.jchf.2019.01.011_bib64","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1161\/CIRCULATIONAHA.116.025629","article-title":"Weight loss and heart failure: a nationwide study of gastric bypass surgery versus intensive lifestyle treatment","volume":"135","author":"Sundstrom","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib65","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.hfc.2015.03.001","article-title":"Heart failure prevention and team-based Interventions","volume":"11","author":"Heidenreich","year":"2015","journal-title":"Heart Fail Clin"},{"key":"10.1016\/j.jchf.2019.01.011_bib66","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1001\/jama.2015.4260","article-title":"Prevalence of the metabolic syndrome in the United States, 2003-2012","volume":"313","author":"Aguilar","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.jchf.2019.01.011_bib67","first-page":"1008","article-title":"Pivotal role of excess intra-abdominal adipose in the pathogenesis of metabolic\/obese HFpEF","volume":"6","author":"Kitzman","year":"2018","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2019.01.011_bib68","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1161\/CIRCHEARTFAILURE.115.002143","article-title":"Association between use of statins and mortality in patients with heart failure and ejection fraction of\u00a0\u226550","volume":"8","author":"Alehagen","year":"2015","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib69","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1161\/CIRCULATIONAHA.113.001475","article-title":"Temporal relationship and prognostic significance of atrial fibrillation in heart failure patients with preserved ejection fraction: a community-based study","volume":"128","author":"Zakeri","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2019.01.011_bib70","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1002\/ejhf.1295","article-title":"Rationale and design of the phase 2b clinical trials to study the effects of the partial adenosine A1-receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced (PANTHEON) and preserved (PANACHE) ejection fraction","volume":"20","author":"Voors","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2019.01.011_bib71","doi-asserted-by":"crossref","first-page":"iii14","DOI":"10.1136\/hrt.2005.070342","article-title":"Gender and heart failure: a population perspective","volume":"92 Suppl 3","author":"Mehta","year":"2006","journal-title":"Heart"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177919300356?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177919300356?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:50:42Z","timestamp":1761972642000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177919300356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":70,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S2213177919300356"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2019.01.011","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary Prevention of Heart Failure in\u00a0Women","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2019.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}