{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:34:54Z","timestamp":1790710494819,"version":"4.1.0"},"reference-count":89,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jchf.2023.07.016","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T14:01:38Z","timestamp":1692626498000},"page":"1055-1069","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"P2","title":["Mitral Interventions in Heart\u00a0Failure"],"prefix":"10.1016","volume":"11","author":[{"given":"Matthew M.","family":"Lander","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2606-055X","authenticated-orcid":false,"given":"Michael I.","family":"Brener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3457-6887","authenticated-orcid":false,"given":"Kashish","family":"Goel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4211-8587","authenticated-orcid":false,"given":"Paul C.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7502-8054","authenticated-orcid":false,"given":"Nathan J.","family":"Verlinden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4067-7844","authenticated-orcid":false,"given":"Sandip","family":"Zalawadiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JoAnn","family":"Lindenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7280-5268","authenticated-orcid":false,"given":"Manreet K.","family":"Kanwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jchf.2023.07.016_bib1","article-title":"Severity of functional mitral regurgitation on admission for acute decompensated heart failure predicts long-term risk of rehospitalization and death","volume":"11","author":"Kataria","year":"2022","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jchf.2023.07.016_bib2","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/eurjhf\/hfq014","article-title":"Prognostic implications of functional mitral regurgitation according to the severity of the underlying chronic heart failure: a long-term outcome study","volume":"12","author":"Bursi","year":"2010","journal-title":"Eur J Heart Fail"},{"issue":"13","key":"10.1016\/j.jchf.2023.07.016_bib3","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2008.05.007","article-title":"2008 focused update incorporated into the ACC\/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"52","author":"Bonow","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib4","first-page":"e521","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"129","author":"Nishimura","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib5","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2023.07.016_bib6","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1056\/NEJMoa1806640","article-title":"Transcatheter mitral-valve repair in patients with heart failure","volume":"379","author":"Stone","year":"2018","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib7","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1056\/NEJMoa1805374","article-title":"Percutaneous repair or medical treatment for secondary mitral regurgitation","volume":"379","author":"Obadia","year":"2018","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib8","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1001\/jamacardio.2017.2976","article-title":"Survival and cardiovascular outcomes of patients with secondary mitral regurgitation: a systematic review and meta-analysis","volume":"2","author":"Sannino","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib9","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/ejechocard\/jeq153","article-title":"Anatomy of the mitral valve: understanding the mitral valve complex in mitral regurgitation","volume":"11","author":"McCarthy","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.jchf.2023.07.016_bib10","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1161\/CIRCULATIONAHA.107.755942","article-title":"Left ventricular response to mitral regurgitation: implications for management","volume":"118","author":"Gaasch","year":"2008","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jchf.2023.07.016_bib11","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"77","author":"Otto","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib12","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1093\/eurheartj\/ehab086","volume":"42","author":"Coats","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2023.07.016_bib13","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1016\/j.jacc.2020.02.005","article-title":"2020 focused update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"75","author":"Bonow","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib14","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ahj.2007.09.002","article-title":"Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: difference between functional mitral regurgitation and prolapse regurgitation","volume":"155","author":"Matsumura","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2023.07.016_bib15","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jacc.2008.05.028","article-title":"Effect of dynamic flow rate and orifice area on mitral regurgitant stroke volume quantification using the proximal isovelocity surface area method","volume":"52","author":"Buck","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib16","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jchf.2023.07.016_bib17","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.amjcard.2005.12.065","article-title":"Comparison of orifice area by transthoracic three-dimensional Doppler echocardiography versus proximal isovelocity surface area (PISA) method for assessment of mitral regurgitation","volume":"97","author":"Iwakura","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib18","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.amjcard.2015.10.045","article-title":"Comparative assessment of mitral regurgitation severity by transthoracic echocardiography and cardiac magnetic resonance using an integrative and quantitative approach","volume":"117","author":"Lopez-Mattei","year":"2016","journal-title":"Am J Cardiol"},{"issue":"17","key":"10.1016\/j.jchf.2023.07.016_bib19","first-page":"e263","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"79","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib20","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.jacc.2020.05.079","article-title":"Effectiveness of medical therapy for functional mitral regurgitation in heart failure with reduced ejection fraction","volume":"76","author":"Sannino","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib21","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/ehjci\/jeac068","article-title":"Guideline directed medical therapy and reduction of secondary mitral regurgitation","volume":"23","author":"Spinka","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jchf.2023.07.016_bib22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.jacc.2020.11.008","article-title":"Randomized trial of empagliflozin in nondiabetic patients with heart failure and reduced ejection fraction","volume":"77","author":"Santos-Gallego","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib23","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1002\/ehf2.12737","article-title":"Modifications of medical treatment and outcome after percutaneous correction of secondary mitral regurgitation","volume":"7","author":"Stolfo","year":"2020","journal-title":"ESC Heart Fail"},{"key":"10.1016\/j.jchf.2023.07.016_bib24","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0041-1345(01)02717-8","article-title":"Effect of carvedilol therapy on functional mitral regurgitation, ventricular remodeling, and contractility in patients with heart failure due to left ventricular systolic dysfunction","volume":"34","author":"Comin-Colet","year":"2002","journal-title":"Transplant Proc"},{"issue":"7","key":"10.1016\/j.jchf.2023.07.016_bib25","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1136\/hrt.2002.009696","article-title":"The impact of baseline left ventricular size and mitral regurgitation on reverse left ventricular remodelling in response to carvedilol: size doesn\u2019t matter","volume":"90","author":"Kotlyar","year":"2004","journal-title":"Heart"},{"key":"10.1016\/j.jchf.2023.07.016_bib26","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S1388-9842(03)00105-3","volume":"5","author":"Waagstein","year":"2003","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2023.07.016_bib27","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1136\/hrt.72.1.63","article-title":"Effect of captopril on functional mitral regurgitation in dilated heart failure: a randomised double blind placebo controlled trial","volume":"72","author":"Seneviratne","year":"1994","journal-title":"Br Heart J"},{"key":"10.1016\/j.jchf.2023.07.016_bib28","article-title":"Effects of the angiotensin-receptor neprilysin inhibitor on cardiac reverse remodeling: meta-analysis","volume":"8","author":"Wang","year":"2019","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jchf.2023.07.016_bib29","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1056\/NEJMoa1409077","article-title":"Angiotensin-neprilysin inhibition versus enalapril in heart failure","volume":"371","author":"McMurray","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib30","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1161\/CIRCULATIONAHA.118.037077","article-title":"Angiotensin receptor neprilysin inhibitor for functional mitral regurgitation","volume":"139","author":"Kang","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib31","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1161\/CIRCULATIONAHA.122.061693","article-title":"Association between sacubitril\/valsartan initiation and mitral regurgitation severity in heart failure with reduced ejection fraction: the PROVE-HF study","volume":"146","author":"Januzzi","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib32","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0735-1097(96)00288-4","article-title":"Vasoactive drugs in chronic regurgitant lesions of the mitral and aortic valves","volume":"28","author":"Levine","year":"1996","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.jchf.2023.07.016_bib33","first-page":"791","article-title":"Guideline-directed medical therapy tolerability in patients with heart failure and mitral regurgitation: the COAPT trial","volume":"11","author":"Cox","year":"2023","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2023.07.016_bib34","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jacc.2018.04.070","article-title":"Medical therapy for heart failure with reduced ejection fraction","volume":"72","author":"Greene","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib35","first-page":"806","article-title":"Optimizing background therapy for heart failure in clinical trials","volume":"11","author":"Desai","year":"2023","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2023.07.016_bib36","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0735-1097(02)02937-6","article-title":"Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure","volume":"41","author":"Breithardt","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib37","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/europace\/eur047","article-title":"Impact of cardiac resynchronization therapy on the severity of mitral regurgitation","volume":"13","author":"Di Biase","year":"2011","journal-title":"Europace"},{"key":"10.1016\/j.jchf.2023.07.016_bib38","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/eurheartj\/ehn063","article-title":"Mechanism of improvement in mitral regurgitation after cardiac resynchronization therapy","volume":"29","author":"Ypenburg","year":"2008","journal-title":"Eur Heart J"},{"issue":"22","key":"10.1016\/j.jchf.2023.07.016_bib39","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1056\/NEJMoa2300213","article-title":"Five-year follow-up after transcatheter repair of secondary mitral regurgitation","volume":"388","author":"Stone","year":"2023","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib40","first-page":"684","article-title":"prognostic importance of health status versus functional status in heart failure and secondary mitral regurgitation","volume":"9","author":"Arnold","year":"2021","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jchf.2023.07.016_bib41","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1002\/ejhf.1616","article-title":"Percutaneous repair or medical treatment for secondary mitral regurgitation: outcomes at 2 years","volume":"21","author":"Iung","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2023.07.016_bib42","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jcmg.2018.11.006","article-title":"Proportionate and disproportionate functional mitral regurgitation: a new conceptual framework that reconciles the results of the MITRA-FR and COAPT trials","volume":"12","author":"Grayburn","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jchf.2023.07.016_bib43","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.echo.2021.08.002","article-title":"Transcatheter edge-to-edge repair in proportionate versus disproportionate functional mitral regurgitation","volume":"35","author":"Ooms","year":"2022","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jchf.2023.07.016_bib44","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1001\/jamacardio.2020.7200","article-title":"Association of effective regurgitation orifice area to left ventricular end-diastolic volume ratio with transcatheter mitral valve repair outcomes: a secondary analysis of the COAPT trial","volume":"6","author":"Lindenfeld","year":"2021","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib45","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1009355","article-title":"Percutaneous repair or surgery for mitral regurgitation","volume":"364","author":"Feldman","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib46","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.jcin.2023.01.010","article-title":"Contemporary outcomes following transcatheter edge-to-edge repair: 1-year results from the EXPAND study","volume":"16","author":"Kar","year":"2023","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib47","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.jcin.2022.06.035","article-title":"Transcatheter edge-to-edge repair for atrial functional mitral regurgitation: effective therapy or elusive target?","volume":"15","author":"Alkhouli","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib48","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1016\/j.jcin.2022.06.005","article-title":"Transcatheter edge-to-edge repair for atrial secondary mitral regurgitation","volume":"15","author":"Tanaka","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib49","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.jcin.2022.07.023","article-title":"Clinical outcomes with transcatheter edge-to-edge repair in atrial functional MR from the EXPAND study","volume":"15","author":"Sodhi","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib50","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1016\/j.jcin.2022.10.028","article-title":"Mitral valve transcatheter edge-to-edge repair using MitraClip or PASCAL: a multicenter propensity score-matched comparison","volume":"15","author":"Schneider","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib51","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1016\/j.jcin.2022.10.008","article-title":"Early outcomes of 2 mitral valve transcatheter leaflet approximation devices: a propensity score-matched multicenter comparison","volume":"15","author":"Mauri","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib52","first-page":"518","article-title":"Transcatheter mitral valve repair in a high-surgical risk patient with severe degenerative mitral regurgitation using the novel DragonFly Transcatheter Repair device-first in man implantation in China","volume":"99","author":"Liu","year":"2022","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jchf.2023.07.016_bib53","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.amjcard.2021.02.022","article-title":"Reasons for screen failure for transcatheter mitral valve repair and replacement","volume":"148","author":"Forrestal","year":"2021","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib54","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.jacc.2021.08.060","article-title":"2-year outcomes of transcatheter mitral valve replacement in patients with severe symptomatic mitral regurgitation","volume":"78","author":"Muller","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib55","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jacc.2017.10.061","article-title":"Early experience with new transcatheter mitral valve replacement","volume":"71","author":"Bapat","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib56","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1016\/j.jcin.2020.06.040","article-title":"Transcatheter mitral valve replacement with the transseptal EVOQUE system","volume":"13","author":"Webb","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib57","first-page":"761","article-title":"Transcatheter mitral valve therapy with novel supra-annular AltaValve: first experience in the United States","volume":"1","author":"Goel","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Case Rep"},{"key":"10.1016\/j.jchf.2023.07.016_bib58","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/j.jcin.2017.06.046","article-title":"Transcatheter mitral valve implantation using the HighLife system","volume":"10","author":"Barbanti","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib59","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.jcin.2020.08.006","article-title":"Early experience with a novel transfemoral mitral valve implantation system in complex degenerative mitral regurgitation","volume":"13","author":"Alperi","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib60","doi-asserted-by":"crossref","first-page":"e163","DOI":"10.1016\/j.jcin.2020.05.032","article-title":"2-year follow-up after transseptal transcatheter mitral valve replacement with the Cardiovalve","volume":"13","author":"Maisano","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib61","doi-asserted-by":"crossref","unstructured":"Mangieri A, Cannata F, Cozzi O, et\u00a0al. A fully percutaneous transeptal transcatheter mitral valve replacement with a novel device. J Am Coll Cardiol Intv. Published online May 9, 2023. https:\/\/doi.org\/10.1016\/j.jcin.2023.04.040","DOI":"10.1016\/j.jcin.2023.04.040"},{"key":"10.1016\/j.jchf.2023.07.016_bib62","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/eurjhf\/hfs076","article-title":"Treatment of functional mitral regurgitation by percutaneous annuloplasty: results of the TITAN trial","volume":"14","author":"Siminiak","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2023.07.016_bib63","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2016-000411","article-title":"Coronary sinus-based percutaneous annuloplasty as treatment for functional mitral regurgitation: the TITAN II trial","volume":"3","author":"Lipiecki","year":"2016","journal-title":"Open Heart"},{"key":"10.1016\/j.jchf.2023.07.016_bib64","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.123.013045","article-title":"Transcatheter mitral valve replacement versus medical therapy for secondary mitral regurgitation: a propensity score-matched comparison","volume":"16","author":"Ludwig","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jchf.2023.07.016_bib65","doi-asserted-by":"crossref","first-page":"4540","DOI":"10.21037\/jtd.2018.07.07","article-title":"Functional mitral regurgitation: an overview for surgical management framework","volume":"10","author":"Nappi","year":"2018","journal-title":"J\u00a0Thorac Dis"},{"key":"10.1016\/j.jchf.2023.07.016_bib66","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1161\/CIRCULATIONAHA.112.143818","article-title":"Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial","volume":"126","author":"Chan","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib67","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1056\/NEJMoa1512913","article-title":"Two-year outcomes of surgical treatment of severe ischemic mitral regurgitation","volume":"374","author":"Goldstein","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib68","first-page":"524","article-title":"2021 ESC\/EACTS guidelines for the management of valvular heart disease: developed by the Task Force for the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"75","author":"Vahanian","year":"2022","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.jchf.2023.07.016_bib69","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jtcvs.2021.04.052","article-title":"2021: the American Association for Thoracic Surgery Expert Consensus Document: coronary artery bypass grafting in patients with ischemic cardiomyopathy and heart failure","volume":"162","author":"Bakaeen","year":"2021","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jchf.2023.07.016_bib70","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1053\/j.semtcvs.2019.10.007","article-title":"Left ventricular stroke work index associated with outcome after mitral valve surgery for functional regurgitation in nonischemic dilated cardiomyopathy","volume":"32","author":"Kashiyama","year":"2020","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jchf.2023.07.016_bib71","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1161\/CIRCULATIONAHA.106.649236","article-title":"Preoperative posterior leaflet angle accurately predicts outcome after restrictive mitral valve annuloplasty for ischemic mitral regurgitation","volume":"115","author":"Magne","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2023.07.016_bib72","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1056\/NEJMoa041451","article-title":"Quantitative determinants of the outcome of asymptomatic mitral regurgitation","volume":"352","author":"Enriquez-Sarano","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jchf.2023.07.016_bib73","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1016\/j.jacc.2019.09.017","article-title":"Echocardiographic outcomes after transcatheter leaflet approximation in patients with secondary mitral regurgitation: the COAPT trial","volume":"74","author":"Asch","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib74","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1016\/j.jacc.2021.10.011","article-title":"Outcomes stratified by adapted inclusion criteria after mitral edge-to-edge repair","volume":"78","author":"Koell","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib75","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/S0735-1097(00)00846-9","article-title":"Cardiogenic shock due to acute severe mitral regurgitation complicating acute myocardial infarction: a report from the SHOCK Trial Registry","volume":"36","author":"Thompson","year":"2000","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib76","first-page":"426","article-title":"Transcatheter edge-to-edge repair in patients with mitral regurgitation and cardiogenic shock: a new therapeutic target","volume":"28","author":"Jung","year":"2022","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.jchf.2023.07.016_bib77","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1016\/j.jacc.2022.09.028","article-title":"Transcatheter treatment of mitral regurgitation in cardiogenic shock","volume":"80","author":"Lurz","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib78","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/j.jacc.2022.09.006","article-title":"Transcatheter edge-to-edge mitral valve repair in patients with severe mitral regurgitation and cardiogenic shock","volume":"80","author":"Simard","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib79","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ahj.2022.08.008","article-title":"Transcatheter mitral valve repair for inotrope dependent cardiogenic shock\u2013design and rationale of the CAPITAL MINOS trial","volume":"254","author":"Parlow","year":"2022","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2023.07.016_bib80","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.healun.2020.09.005","article-title":"MitraClip in secondary mitral regurgitation as a bridge to heart transplantation: 1-year outcomes from the International MitraBridge Registry","volume":"39","author":"Godino","year":"2020","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jchf.2023.07.016_bib81","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/j.jcin.2021.06.039","article-title":"Machine learning identifies clinical parameters to predict mortality in patients undergoing transcatheter mitral valve repair","volume":"14","author":"Zweck","year":"2021","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib82","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.jacc.2021.11.041","article-title":"A\u00a0score to assess mortality after percutaneous mitral valve repair","volume":"79","author":"Raposeiras-Roubin","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib83","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1016\/j.jcin.2022.08.005","article-title":"Prediction of death or HF hospitalization in patients with severe FMR: the COAPT risk score","volume":"15","author":"Shah","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jchf.2023.07.016_bib84","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/j.jacc.2020.03.002","article-title":"Health status changes and outcomes in patients with heart failure and mitral regurgitation: COAPT trial","volume":"75","author":"Arnold","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib85","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.jacc.2022.06.009","article-title":"Management of patients with severe mitral annular calcification: JACC state-of-the-art review","volume":"80","author":"Chehab","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2023.07.016_bib86","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.4244\/EIJ-D-21-00205","article-title":"Transcatheter edge-to-edge mitral valve repair in patients with mitral annulus calcification","volume":"17","author":"Fern\u00e1ndez-Peregrina","year":"2022","journal-title":"EuroIntervention"},{"issue":"3","key":"10.1016\/j.jchf.2023.07.016_bib87","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jtcvs.2019.03.089","article-title":"Right ventricular function and residual mitral regurgitation after left ventricular assist device implantation determines the incidence of right heart failure","volume":"159","author":"Tang","year":"2020","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jchf.2023.07.016_bib88","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/j.healun.2022.03.002","article-title":"Residual mitral regurgitation in patients with left ventricular assist device support - an INTERMACS analysis","volume":"41","author":"Jain","year":"2022","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jchf.2023.07.016_bib89","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.healun.2020.03.003","article-title":"Impact of left ventricular assist device implantation on mitral regurgitation: an analysis from the MOMENTUM 3 trial","volume":"39","author":"Kanwar","year":"2020","journal-title":"J\u00a0Heart Lung Transplant"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177923004122?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177923004122?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:14:21Z","timestamp":1762607661000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177923004122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":89,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S2213177923004122"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2023.07.016","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitral Interventions in Heart\u00a0Failure","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2023.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}