{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:40:08Z","timestamp":1793785208805,"version":"4.6.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jchf.2025.102531","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T22:06:38Z","timestamp":1751666798000},"page":"102531","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Mineralocorticoid Receptor Antagonists in Myocardial Infarction Patients"],"prefix":"10.1016","volume":"13","author":[{"given":"Marc-Andr\u00e9","family":"d\u2019Entremont","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zain","family":"Cheema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertram","family":"Pitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasko","family":"Kedev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Hein","family":"Cornel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9414-0885","authenticated-orcid":false,"given":"Goran","family":"Stankovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6677-6229","authenticated-orcid":false,"given":"Robert","family":"Storey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Bossard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Chauhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Montalescot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzin","family":"Beygui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7456-1570","authenticated-orcid":false,"given":"Faiez","family":"Zannad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjit","family":"Jolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchf.2025.102531_bib1","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes: developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC)","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib2","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","article-title":"Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction","volume":"348","author":"Pitt","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jchf.2025.102531_bib3","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1093\/eurheartj\/ehu164","article-title":"Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: the Randomized Double-Blind Reminder Study","volume":"35","author":"Montalescot","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib4","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1016\/j.jacc.2016.02.033","article-title":"Early aldosterone blockade in acute myocardial infarction: the ALBATROSS randomized clinical trial","volume":"67","author":"Beygui","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2025.102531_bib5","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ahj.2017.09.010","article-title":"Mineralocorticoid receptor antagonists in patients with acute myocardial infarction\u2014a systematic review and meta-analysis of randomized trials","volume":"195","author":"Bossard","year":"2018","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib6","article-title":"PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.jchf.2025.102531_bib7","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.jchf.2025.102531_bib8","doi-asserted-by":"crossref","first-page":"4861","DOI":"10.1002\/sim.6301","article-title":"The Peto odds ratio viewed as a new effect measure","volume":"33","author":"Brockhaus","year":"2014","journal-title":"Stat Med"},{"key":"10.1016\/j.jchf.2025.102531_bib9","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.jchf.2025.102531_bib10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1067\/mhj.2001.111258","article-title":"Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction","volume":"141","author":"Modena","year":"2001","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib11","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ahj.2005.03.032","article-title":"Effects of canrenoate plus angiotensin-converting enzyme inhibitors versus angiotensin-converting enzyme inhibitors alone on systolic and diastolic function in patients with acute anterior myocardial infarction","volume":"150","author":"Di Pasquale","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib12","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1080\/00365510902802278","article-title":"Effects of aldosterone blockade on left ventricular function and clinical status during acute myocardial infarction","volume":"69","author":"Uzunhasan","year":"2009","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.jchf.2025.102531_bib13","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.ahj.2009.04.001","article-title":"Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect?","volume":"157","author":"Weir","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib14","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1097\/MCA.0b013e32833fd243","article-title":"The effects of spironolactone on atrial remodeling in patients with preserved left ventricular function after an acute myocardial infarction: a randomized follow-up study","volume":"21","author":"Kayrak","year":"2010","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.jchf.2025.102531_bib15","doi-asserted-by":"crossref","first-page":"48","DOI":"10.5847\/wjem.j.issn.1920-8642.2013.01.009","article-title":"Effect of spironolactone on cardiac remodeling after acute myocardial infarction","volume":"4","author":"Wu","year":"2013","journal-title":"World J Emerg Med"},{"key":"10.1016\/j.jchf.2025.102531_bib16","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ahj.2019.02.005","article-title":"Mineralocorticoid receptor antagonist pre-treatment and early post-treatment to minimize reperfusion injury after ST-elevation myocardial infarction: the MINIMIZE STEMI trial","volume":"211","author":"Bulluck","year":"2019","journal-title":"Am Heart J"},{"key":"10.1016\/j.jchf.2025.102531_bib17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ahj.2024.06.007","article-title":"Design and rationale of the CLEAR SYNERGY (OASIS 9) trial: A 2x2 factorial randomized controlled trial of colchicine versus placebo and spironolactone vs placebo in patients with myocardial infarction","volume":"275","author":"d'Entremont","year":"2024","journal-title":"Am Heart J"},{"issue":"7","key":"10.1016\/j.jchf.2025.102531_bib18","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1056\/NEJMoa2405923","article-title":"Routine spironolactone in acute myocardial infarction","volume":"392","author":"Jolly","year":"2025","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jchf.2025.102531_bib19","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa2104508","article-title":"Angiotensin receptor\u2013neprilysin inhibition in acute myocardial infarction","volume":"385","author":"Pfeffer","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jchf.2025.102531_bib20","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1056\/NEJMoa2314051","article-title":"Empagliflozin after acute myocardial infarction","volume":"390","author":"Butler","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jchf.2025.102531_bib21","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1161\/CIR.0b013e31826890b0","article-title":"Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models","volume":"126","author":"Morrow","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2025.102531_bib22","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.019167","article-title":"Predictors of the use of mineralocorticoid receptor antagonists in patients with left ventricular dysfunction post\u2013ST-segment elevation myocardial infarction","volume":"10","author":"Wong","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jchf.2025.102531_bib23","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1056\/NEJMoa2407107","article-title":"Finerenone in heart failure with mildly reduced or preserved ejection fraction","volume":"391","author":"Solomon","year":"2024","journal-title":"N Engl J Med"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925004585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925004585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T03:38:07Z","timestamp":1788233887000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177925004585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S2213177925004585"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102531","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mineralocorticoid Receptor Antagonists in Myocardial Infarction Patients","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102531","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}],"article-number":"102531"}}