{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T11:43:36Z","timestamp":1792928616874,"version":"4.5.0"},"reference-count":75,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jchf.2025.102614","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T01:05:41Z","timestamp":1755824741000},"page":"102614","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Contemporary Antibody-Mediated Rejection in Heart Transplantation"],"prefix":"10.1016","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6932-2188","authenticated-orcid":false,"given":"Aditya","family":"Mehta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0493-1326","authenticated-orcid":false,"given":"Ersilia M.","family":"DeFilippis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7362-0513","authenticated-orcid":false,"given":"Josef","family":"Stehlik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette M.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon A.","family":"Kobashigawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8175-168X","authenticated-orcid":false,"given":"Palak","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib1","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.healun.2020.07.010","article-title":"The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 37th Adult Heart Transplantation Report\u20142020; focus on deceased donor characteristics","volume":"39","author":"Khush","year":"2020","journal-title":"J Heart Lung Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib2","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1097\/TP.0b013e318186d734","article-title":"Late onset antibody-mediated rejection and endothelial localization of vascular endothelial growth factor are associated with development of cardiac allograft vasculopathy","volume":"86","author":"Bayliss","year":"2008","journal-title":"Transplantation"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib3","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.jchf.2022.08.005","article-title":"Safety of right and left ventricular endomyocardial biopsy in heart transplantation and cardiomyopathy patients","volume":"10","author":"Bermpeis","year":"2022","journal-title":"JACC Heart Fail"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib4","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.healun.2024.10.006","article-title":"Pathologist interrater reliability and clinical implications of elevated donor-derived cell-free DNA beyond heart transplant rejection, on behalf of the GRAfT investigators","volume":"44","author":"Mehta","year":"2025","journal-title":"J Heart Lung Transplant"},{"issue":"18","key":"10.1016\/j.jchf.2025.102614_bib5","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1161\/CIR.0000000000000093","article-title":"Antibody-mediated rejection in cardiac transplantation: emerging knowledge in diagnosis and management. A scientific statement from the American Heart Association: Endorsed by the International Society for Heart and Lung Transplantation","volume":"131","author":"Colvin","year":"2015","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib6","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.healun.2013.08.011","article-title":"The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation","volume":"32","author":"Berry","year":"2013","journal-title":"J Heart Lung Transplant"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib7","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.healun.2016.10.016","article-title":"Donor-specific anti-HLA antibodies with antibody-mediated rejection and long-term outcomes following heart transplantation","volume":"36","author":"Clerkin","year":"2017","journal-title":"J Heart Lung Transplant"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib8","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.healun.2015.03.002","article-title":"Late antibody-mediated rejection after heart transplantation: mortality, graft function, and fulminant cardiac allograft vasculopathy","volume":"34","author":"Coutance","year":"2015","journal-title":"J Heart Lung Transplant"},{"issue":"3","key":"10.1016\/j.jchf.2025.102614_bib9","first-page":"191","article-title":"Acute vascular rejection involving the major coronary arteries of a cardiac allograft","volume":"7","author":"Yowell","year":"1988","journal-title":"J Heart Transplant"},{"issue":"11","key":"10.1016\/j.jchf.2025.102614_bib10","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.healun.2005.03.019","article-title":"Revision of the 1990 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Heart Rejection","volume":"24","author":"Stewart","year":"2005","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib11","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.healun.2005.09.003","article-title":"Acute antibody-mediated rejection of cardiac transplants","volume":"25","author":"Reed","year":"2006","journal-title":"J Heart Lung Transplant"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ajt.2023.10.004","article-title":"Report of the 2022 Banff Heart Concurrent: focus on non-human leukocyte antigen antibodies in rejection and the pathology of \u201cmixed\u201d rejection","volume":"24","author":"Fedrigo","year":"2024","journal-title":"Am J Transplant"},{"issue":"3","key":"10.1016\/j.jchf.2025.102614_bib13","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.healun.2010.11.003","article-title":"Report from a consensus conference on antibody-mediated rejection in heart transplantation","volume":"30","author":"Kobashigawa","year":"2011","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.jchf.2025.102614_bib14","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/236720","article-title":"The natural history of biopsy-negative rejection after heart transplantation","volume":"2013","author":"Tang","year":"2013","journal-title":"J Transplant"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib15","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/j.ajt.2024.03.031","article-title":"Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival","volume":"24","author":"Halloran","year":"2024","journal-title":"Am J Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib16","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.124.011592","article-title":"Redefining cardiac antibody-mediated rejection with donor-specific antibodies and graft dysfunction","volume":"17","author":"Goldberg","year":"2024","journal-title":"Circ Heart Fail"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib17","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/01.tp.0000180564.14050.49","article-title":"The presence of HLA-directed antibodies after heart transplantation is associated with poor allograft outcome","volume":"80","author":"Tambur","year":"2005","journal-title":"Transplantation"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib18","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/TP.0000000000000757","article-title":"The role of natural killer cells in humoral rejection","volume":"99","author":"Resch","year":"2015","journal-title":"Transplantation"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib19","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.humimm.2020.04.003","article-title":"HLA-DQ mismatches stimulate de novo donor specific antibodies in heart transplant recipients","volume":"81","author":"Zhang","year":"2020","journal-title":"Hum Immunol"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib20","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1111\/tri.13324","article-title":"Donor specific HLA antibodies & allograft injury: mechanisms, methods of detection, manifestations and management","volume":"31","author":"McCaughan","year":"2018","journal-title":"Transpl Int"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib21","doi-asserted-by":"crossref","first-page":"S329","DOI":"10.1016\/j.ajt.2025.01.024","article-title":"OPTN\/SRTR 2023 Annual Data Report: Heart","volume":"25","author":"Colvin","year":"2025","journal-title":"Am J Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib22","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000000598","article-title":"Sensitization in heart transplantation: emerging knowledge: a scientific statement from the American Heart Association","volume":"139","author":"Colvin","year":"2019","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib23","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.healun.2025.02.1690","article-title":"Summary of the International Society for Heart and Lung Transplantation consensus conference on emerging understanding of antibodies and antibody-mediated rejection in heart transplantation","volume":"44","author":"Kobashigawa","year":"2025","journal-title":"J Heart Lung Transplant"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib24","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.healun.2022.10.015","article-title":"The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients","volume":"42","author":"Velleca","year":"2023","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1016\/j.jchf.2025.102614_bib25","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ajt.2022.11.009","article-title":"Sensitization in Transplantation: Assessment of Risk 2022 Working Group Meeting Report","volume":"23","author":"Tambur","year":"2023","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib26","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14914","article-title":"Donor specific antibodies association with survival and adverse events after heart transplantation: a single center retrospective study between 2006 and 2021","volume":"37","author":"Akhtar","year":"2023","journal-title":"Clin Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib27","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14483","article-title":"The effects of donor-specific antibody characteristics on cardiac allograft vasculopathy","volume":"35","author":"Wang","year":"2021","journal-title":"Clin Transplant"},{"issue":"9","key":"10.1016\/j.jchf.2025.102614_bib28","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1111\/ajt.15871","article-title":"Profiling non-HLA antibody responses in antibody-mediated rejection following heart transplantation","volume":"20","author":"See","year":"2020","journal-title":"Am J Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib29","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1097\/TP.0000000000003551","article-title":"A comprehensive overview of the clinical relevance and treatment options for antibody-mediated rejection associated with non-HLA antibodies","volume":"105","author":"Kardol-Hoefnagel","year":"2021","journal-title":"Transplantation"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib30","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1111\/ajt.15863","article-title":"Discovery of non-HLA antibodies associated with cardiac allograft rejection and development and validation of a non-HLA antigen multiplex panel: from bench to bedside","volume":"20","author":"Butler","year":"2020","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib31","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1161\/CIRCULATIONAHA.123.062847","article-title":"Selection and interpretation of molecular diagnostics in heart transplantation","volume":"148","author":"Goldberg","year":"2023","journal-title":"Circulation"},{"issue":"241","key":"10.1016\/j.jchf.2025.102614_bib32","doi-asserted-by":"crossref","first-page":"241ra77","DOI":"10.1126\/scitranslmed.3007803","article-title":"Circulating cell-free DNA enables noninvasive diagnosis of heart transplant rejection","volume":"6","author":"De Vlaminck","year":"2014","journal-title":"Sci Transl Med"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib33","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1111\/ajt.15339","article-title":"Noninvasive detection of graft injury after heart transplant using donor-derived cell-free DNA: a prospective multicenter study","volume":"19","author":"Khush","year":"2019","journal-title":"Am J Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib34","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.healun.2022.04.002","article-title":"A novel donor-derived cell-free DNA assay for the detection of acute rejection in heart transplantation","volume":"41","author":"Kim","year":"2022","journal-title":"J Heart Lung Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib35","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1161\/CIRCULATIONAHA.120.049098","article-title":"Cell-free DNA to detect heart allograft acute rejection","volume":"143","author":"Agbor-Enoh","year":"2021","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jchf.2025.102614_bib36","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14295","article-title":"Identification of cell-free DNA methylation patterns unique to the human left ventricle as a potential indicator of acute cellular rejection","volume":"35","author":"Pattar","year":"2021","journal-title":"Clin Transplant"},{"issue":"11","key":"10.1016\/j.jchf.2025.102614_bib37","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.healun.2017.05.029","article-title":"Building a tissue-based molecular diagnostic system in heart transplant rejection: the heart Molecular Microscope Diagnostic (MMDx) System","volume":"36","author":"Halloran","year":"2017","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib38","first-page":"III66","article-title":"Diastolic dysfunction during acute cardiac allograft rejection","volume":"81","author":"Amende","year":"1990","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib39","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.cardfail.2014.02.006","article-title":"Left ventricular longitudinal strain by speckle-tracking echocardiography is associated with treatment-requiring cardiac allograft rejection","volume":"20","author":"Sera","year":"2014","journal-title":"J Card Fail"},{"issue":"6","key":"10.1016\/j.jchf.2025.102614_bib40","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.7863\/ultra.15.07013","article-title":"Three-dimensional speckle-tracking echocardiographic monitoring of acute rejection in heart transplant recipients","volume":"35","author":"Du","year":"2016","journal-title":"J Ultrasound Med"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib41","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s10554-024-03297-3","article-title":"Speckle-tracking echocardiography of left and right ventricle and acute cellular rejection in orthotropic heart transplantation: a systematic review and meta-analysis","volume":"41","author":"Xourgia","year":"2025","journal-title":"Int J Cardiovasc Imaging"},{"issue":"11","key":"10.1016\/j.jchf.2025.102614_bib42","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1093\/ehjci\/jeab212","article-title":"Speckle-tracking-based global longitudinal and circumferential strain detect early signs of antibody-mediated rejection in heart transplant patients","volume":"23","author":"Ciarka","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib43","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1111\/echo.14544","article-title":"Myocardial deformation and acute cellular rejection after heart transplantation: impact of inter-vendor variability in diagnostic effectiveness","volume":"36","author":"Ruiz-Ortiz","year":"2019","journal-title":"Echocardiography"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib44","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.healun.2014.12.020","article-title":"Correlation of cardiovascular magnetic resonance imaging findings and endomyocardial biopsy results in patients undergoing screening for heart transplant rejection","volume":"34","author":"Butler","year":"2015","journal-title":"J Heart Lung Transplant"},{"issue":"25","key":"10.1016\/j.jchf.2025.102614_bib45","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1161\/CIRCULATIONAHA.121.057006","article-title":"Cardiovascular magnetic resonance for rejection surveillance after cardiac transplantation","volume":"145","author":"Anthony","year":"2022","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib46","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13704","article-title":"Quantitative myocardial tissue characterization by cardiac magnetic resonance in heart transplant patients with suspected cardiac rejection","volume":"33","author":"Miller","year":"2019","journal-title":"Clin Transplant"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib47","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1007\/s12350-021-02742-3","article-title":"Prognostic value of myocardial flow reserve obtained by 82-rubidium positron emission tomography in long-term follow-up after heart transplantation","volume":"29","author":"Nelson","year":"2022","journal-title":"J Nucl Cardiol"},{"issue":"1","key":"10.1016\/j.jchf.2025.102614_bib48","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/01.CIR.90.1.204","article-title":"Myocardial blood flow at rest and during pharmacological vasodilation in cardiac transplants during and after successful treatment of rejection","volume":"90","author":"Chan","year":"1994","journal-title":"Circulation"},{"issue":"1, pt 1","key":"10.1016\/j.jchf.2025.102614_bib49","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jcmg.2018.08.025","article-title":"Serial assessment of coronary flow reserve by rubidium-82 positron emission tomography predicts mortality in heart transplant recipients","volume":"13","author":"Feher","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"issue":"3","key":"10.1016\/j.jchf.2025.102614_bib50","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.healun.2018.12.009","article-title":"International Society of Heart and Lung Transplantation position statement on the role of right heart catheterization in the management of heart transplant recipients","volume":"38","author":"Lim","year":"2019","journal-title":"J Heart Lung Transplant"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib51","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jacc.2015.04.078","article-title":"Pediatric heart transplant recipients and cardiac allograft vasculopathy","volume":"66","author":"Eisen","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib52","doi-asserted-by":"crossref","first-page":"3692","DOI":"10.1016\/j.transproceed.2006.10.060","article-title":"Effect of plasmapheresis for acute humoral rejection after heart transplantation","volume":"38","author":"Wang","year":"2006","journal-title":"Transplant Proc"},{"issue":"8","key":"10.1016\/j.jchf.2025.102614_bib53","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.healun.2023.03.005","article-title":"European multicenter study on the real-world use and clinical impact of extracorporeal photopheresis after heart transplantation","volume":"42","author":"Barten","year":"2023","journal-title":"J Heart Lung Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib54","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13871","article-title":"Induction immunosuppression strategies and long-term outcomes after heart transplantation","volume":"34","author":"Nozohoor","year":"2020","journal-title":"Clin Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib55","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14454","article-title":"Eculizumab for antibody-mediated rejection in heart transplantation: a case-control study","volume":"35","author":"Kittleson","year":"2021","journal-title":"Clin Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib56","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1111\/ajt.16420","article-title":"Complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients","volume":"21","author":"Patel","year":"2021","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib57","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/S0003-4975(02)03824-9","article-title":"Treatment of humoral rejection with rituximab","volume":"74","author":"Garrett","year":"2002","journal-title":"Ann Thorac Surg"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib58","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.healun.2007.01.027","article-title":"Successful management of antibody-mediated cardiac allograft rejection with combined immunoadsorption and anti-CD20 monoclonal antibody treatment: case report and literature review","volume":"26","author":"Kaczmarek","year":"2007","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib59","doi-asserted-by":"crossref","first-page":"147","DOI":"10.7182\/pit2015934","article-title":"Bortezomib-containing regimen for primary treatment of early antibody-mediated cardiac allograft rejection: a case report","volume":"25","author":"Gazdic","year":"2015","journal-title":"Prog Transplant"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.healun.2014.01.112","article-title":"Carfilzomib for refractory antibody mediated rejection and allosensitization in heart transplantation","volume":"33","author":"Sacha","year":"2014","journal-title":"J Heart Lung Transplant"},{"issue":"3","key":"10.1016\/j.jchf.2025.102614_bib61","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/TP.0b013e31823f7eea","article-title":"Rapid reduction in donor-specific anti-human leukocyte antigen antibodies and reversal of antibody-mediated rejection with bortezomib in pediatric heart transplant patients","volume":"93","author":"Morrow","year":"2012","journal-title":"Transplantation"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib62","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.15132","article-title":"Reduction of HLA donor specific antibodies in heart transplant patients treated with proteasome inhibitors for antibody mediated rejection","volume":"37","author":"Horn","year":"2023","journal-title":"Clin Transplant"},{"issue":"7","key":"10.1016\/j.jchf.2025.102614_bib63","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.healun.2021.03.001","article-title":"Impact of carfilzomib-based desensitization on heart transplantation of sensitized candidates","volume":"40","author":"Sriwattanakomen","year":"2021","journal-title":"J Heart Lung Transplant"},{"issue":"4","key":"10.1016\/j.jchf.2025.102614_bib64","doi-asserted-by":"crossref","first-page":"S123","DOI":"10.1016\/j.healun.2016.01.339","article-title":"Durability of bortezomib for treatment of antibody mediated rejection in cardiac transplantation","volume":"35","author":"Cochrane","year":"2016","journal-title":"J Heart Lung Transplant"},{"issue":"12","key":"10.1016\/j.jchf.2025.102614_bib65","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1016\/j.ajt.2023.06.018","article-title":"Daratumumab for antibody-mediated rejection: is it time to target the real culprit?","volume":"23","author":"de Nattes","year":"2023","journal-title":"Am J Transplant"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib66","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa2400763","article-title":"A randomized phase 2 trial of felzartamab in antibody-mediated rejection","volume":"391","author":"Mayer","year":"2024","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib67","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/TP.0000000000004784","article-title":"Feasibility of interleukin-6 receptor blockade in cardiac antibody-mediated rejection","volume":"108","author":"Pottebaum","year":"2024","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.jchf.2025.102614_bib68","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2217\/imt.13.163","article-title":"Immunosuppression following heart transplantation: prospects and challenges","volume":"6","author":"Chang","year":"2014","journal-title":"Immunotherapy"},{"issue":"3","key":"10.1016\/j.jchf.2025.102614_bib69","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.15251","article-title":"Utility of a fusion protein T-cell co-stimulation blocker belatacept in heart transplant recipients: real world experience from a high volume center","volume":"38","author":"Oren","year":"2024","journal-title":"Clin Transplant"},{"issue":"13","key":"10.1016\/j.jchf.2025.102614_bib70","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.3390\/jcm11133731","article-title":"De novo complement-binding anti-HLA antibodies in heart transplanted patients is associated with severe cardiac allograft vasculopathy and poor long-term survival","volume":"11","author":"Baudry","year":"2022","journal-title":"J Clin Med"},{"issue":"9","key":"10.1016\/j.jchf.2025.102614_bib71","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1097\/TP.0000000000004986","article-title":"Comparing plasma donor-derived cell-free DNA to gene expression in endomyocardial biopsies in the Trifecta-Heart study","volume":"108","author":"Halloran","year":"2024","journal-title":"Transplantation"},{"issue":"10","key":"10.1016\/j.jchf.2025.102614_bib72","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.healun.2022.06.019","article-title":"Circulating microRNAs in cellular and antibody-mediated heart transplant rejection","volume":"41","author":"Shah","year":"2022","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1016\/j.jchf.2025.102614_bib73","doi-asserted-by":"crossref","first-page":"15","DOI":"10.36628\/ijhf.2020.0034","article-title":"Heart transplant immunosuppression strategies at Cedars-Sinai Medical Center","volume":"3","author":"Chang","year":"2021","journal-title":"Int J Heart Fail"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib74","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1056\/NEJMoa1612567","article-title":"IgG endopeptidase in highly sensitized patients undergoing transplantation","volume":"377","author":"Jordan","year":"2017","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.jchf.2025.102614_bib75","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2215\/CJN.12031017","article-title":"Immunoglobulin G-degrading enzyme of Streptococcus pyogenes (IdeS), desensitization, and the kidney allocation system: complementary approaches to increase transplantation in highly HLA sensitized patients","volume":"13","author":"Huang","year":"2018","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925005426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925005426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:07:49Z","timestamp":1790129269000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177925005426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":75,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S2213177925005426"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102614","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contemporary Antibody-Mediated Rejection in Heart Transplantation","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102614","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"102614"}}