{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T08:08:13Z","timestamp":1791878893976,"version":"4.3.4"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jchf.2025.102769","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T15:22:25Z","timestamp":1763652145000},"page":"102769","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Hemocompatibility Outcomes With Pharmacological Therapy Following LVAD Implantation"],"prefix":"10.1016","volume":"14","author":[{"given":"Jason N.","family":"Katz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean M.","family":"Connors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis D.","family":"Pagani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich P.","family":"Jorde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Finn","family":"Gustafsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2301-3587","authenticated-orcid":false,"given":"Nir","family":"Uriel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Netuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirnela","family":"Byku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anelechi","family":"Anyanwu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Keebler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sriram","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig H.","family":"Selzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Alexis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasir","family":"Sulemanjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavan","family":"Atluri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"D\u2019Allesandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney","family":"Porter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei San","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8683-7044","authenticated-orcid":false,"given":"Mandeep R.","family":"Mehra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"17","key":"10.1016\/j.jchf.2025.102769_bib1","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJMoa1900486","article-title":"A fully magnetically levitated left ventricular assist device","volume":"380","author":"Mehra","year":"2019","journal-title":"N Engl J Med"},{"issue":"22","key":"10.1016\/j.jchf.2025.102769_bib2","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1001\/jama.2023.23204","article-title":"Aspirin and hemocompatibility events with a left ventricular assist device in advanced heart failure: the ARIES-HM3 randomized clinical trial","volume":"330","author":"Mehra","year":"2023","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.jchf.2025.102769_bib3","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1161\/CIRCULATIONAHA.124.070228","article-title":"Rapid and intensive guideline-directed medical therapy for heart failure: 5 core principles","volume":"150","author":"Greene","year":"2024","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.jchf.2025.102769_bib4","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1002\/ejhf.2275","article-title":"Aspirin and left ventricular assist devices: rationale and design for the international randomized, placebo-controlled, non-inferiority ARIES HM3 trial","volume":"23","author":"Mehra","year":"2021","journal-title":"Eur J Heart Fail"},{"issue":"17","key":"10.1016\/j.jchf.2025.102769_bib5","doi-asserted-by":"crossref","first-page":"e263","DOI":"10.1016\/j.jacc.2021.12.012","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"79","author":"Heidenreich","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jchf.2025.102769_bib6","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.healun.2016.12.016","article-title":"Angiotensin II antagonism is associated with reduced risk for gastrointestinal bleeding caused by arteriovenous malformations in patients with left ventricular assist devices","volume":"36","author":"Houston","year":"2017","journal-title":"J Heart Lung Transplant"},{"issue":"14","key":"10.1016\/j.jchf.2025.102769_bib7","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.jacc.2019.01.051","article-title":"Effect of angiotensin II inhibitors on gastrointestinal bleeding in patients with left ventricular assist devices","volume":"73","author":"Converse","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.jchf.2025.102769_bib8","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1016\/j.healun.2021.08.015","article-title":"Impact of renin-angiotensin-aldosterone system inhibition on morbidity and mortality during long-term continuous-flow left ventricular assist device support: an IMACS report","volume":"40","author":"Brinkley","year":"2021","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1016\/j.jchf.2025.102769_bib9","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1161\/CIRCULATIONAHA.115.019692","article-title":"Elevated angiopoietin-2 level in patients with continuous-flow left ventricular assist devices leads to altered angiogenesis and is associated with higher nonsurgical bleeding","volume":"134","author":"Tabit","year":"2016","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jchf.2025.102769_bib10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2165\/00002018-200124030-00002","article-title":"Interaction between aspirin and ACE inhibitors in patients with heart failure","volume":"24","author":"Mah\u00e9","year":"2001","journal-title":"Drug Saf"},{"issue":"8","key":"10.1016\/j.jchf.2025.102769_bib11","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.118.004899","article-title":"Digoxin is associated with a decreased incidence of angiodysplasia-related gastrointestinal bleeding in patients with continuous-flow left ventricular assist devices","volume":"11","author":"Vukelic","year":"2018","journal-title":"Circ Heart Fail"},{"issue":"20","key":"10.1016\/j.jchf.2025.102769_bib12","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.3390\/jcm11205988","article-title":"Post-implant phosphodiesterase-5 inhibitors in patients with left ventricular assist device: a systematic review and meta-analysis","volume":"11","author":"Xanthopoulos","year":"2022","journal-title":"J Clin Med"},{"issue":"14","key":"10.1016\/j.jchf.2025.102769_bib13","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.jacc.2023.07.019","article-title":"Durable mechanical circulatory support: JACC scientific statement","volume":"82","author":"Tedford","year":"2023","journal-title":"J Am Coll Cardiol"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925006997?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177925006997?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T06:02:30Z","timestamp":1773900150000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177925006997"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2213177925006997"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102769","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemocompatibility Outcomes With Pharmacological Therapy Following LVAD Implantation","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2025.102769","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"102769"}}