{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:52:09Z","timestamp":1792093929797,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,6,1]],"date-time":"2027-06-01T00:00:00Z","timestamp":1811808000000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"NHLBI","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jchf.2026.102947","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T21:17:51Z","timestamp":1770844671000},"page":"102947","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Progression From Exercise-Induced to Resting Left Atrial Hypertension in HFpEF"],"prefix":"10.1016","volume":"14","author":[{"given":"Atsushi","family":"Tada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jwan A.","family":"Naser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichi","family":"Doi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonari","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuro","family":"Ibe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Kazui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh N.V.","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret M.","family":"Redfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry A.","family":"Borlaug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchf.2026.102947_bib1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/s41569-020-0363-2","article-title":"Evaluation and management of heart failure with preserved ejection fraction","volume":"17","author":"Borlaug","year":"2020","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib2","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1161\/CIRCRESAHA.119.313572","article-title":"Heart failure with preserved ejection fraction in perspective","volume":"124","author":"Pfeffer","year":"2019","journal-title":"Circ Res"},{"key":"10.1016\/j.jchf.2026.102947_bib3","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ejhf.1741","article-title":"How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)","volume":"22","author":"Pieske","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib4","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1161\/CIRCHEARTFAILURE.109.930701","article-title":"Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction","volume":"3","author":"Borlaug","year":"2010","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/ejhf.2747","article-title":"Central haemodynamic abnormalities and outcome in patients with unexplained dyspnoea","volume":"25","author":"Omote","year":"2023","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib6","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.117.004750","article-title":"Pulmonary capillary wedge pressure patterns during exercise predict exercise capacity and incident heart failure","volume":"11","author":"Eisman","year":"2018","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jacc.2019.10.048","article-title":"Exercise pulmonary hypertension predicts clinical outcomes in patients with dyspnea on effort","volume":"75","author":"Ho","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib8","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.jchf.2023.01.030","article-title":"Exercise-induced left atrial hypertension in heart failure with preserved ejection fraction","volume":"11","author":"Litwin","year":"2023","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib9","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/eurheartj\/ehy809","article-title":"Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction","volume":"40","author":"Obokata","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2026.102947_bib10","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.jacc.2020.07.009","article-title":"Atrial dysfunction in patients with heart failure with preserved ejection fraction and atrial fibrillation","volume":"76","author":"Reddy","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.jchf.2026.102947_bib12","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.1464","article-title":"Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction","volume":"21","author":"Reddy","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib13","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/ehjci\/jey042","article-title":"Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI\/ASE\/Industry Task Force to Standardize Deformation Imaging","volume":"19","author":"Badano","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jchf.2026.102947_bib14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cardfail.2017.11.005","article-title":"Right heart dysfunction in heart failure with preserved ejection fraction: the impact of atrial fibrillation","volume":"24","author":"Gorter","year":"2018","journal-title":"J Card Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib15","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.cardfail.2020.12.016","article-title":"Impact of right atrial remodeling in heart failure with preserved ejection fraction","volume":"27","author":"Ikoma","year":"2021","journal-title":"J Card Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib16","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1093\/eurheartj\/ehw241","article-title":"Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction","volume":"37","author":"Borlaug","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jchf.2026.102947_bib17","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1161\/CIRCULATIONAHA.116.026807","article-title":"Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction","volume":"136","author":"Obokata","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib18","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1001\/jamacardio.2024.3767","article-title":"Prevalence of HFpEF in isolated severe secondary tricuspid regurgitation","volume":"10","author":"Naser","year":"2025","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib19","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.jcmg.2024.05.019","article-title":"Prevalence, incidence, and outcomes of diastolic dysfunction in isolated tricuspid regurgitation: perhaps not really \u201cisolated\u201d?","volume":"17","author":"Naser","year":"2024","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jchf.2026.102947_bib20","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1161\/CIRCULATIONAHA.122.059486","article-title":"Latent pulmonary vascular disease may alter the response to therapeutic atrial shunt device in heart failure","volume":"145","author":"Borlaug","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib21","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1161\/CIRCULATIONAHA.121.058592","article-title":"Longitudinal evolution of cardiac dysfunction in heart failure and preserved ejection fraction with normal natriuretic peptide levels","volume":"146","author":"Sorimachi","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib22","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1001\/jamacardio.2024.1914","article-title":"Dapagliflozin and right ventricular-pulmonary vascular interaction in heart failure with preserved ejection fraction: a secondary analysis of a randomized clinical trial","volume":"9","author":"Reddy","year":"2024","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib23","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1161\/CIRCULATIONAHA.124.068788","article-title":"Dapagliflozin enhances arterial and venous compliance during exercise in heart failure with preserved ejection fraction: insights from the CAMEO-DAPA trial","volume":"150","author":"Tada","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib24","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1161\/CIRCULATIONAHA.119.044183","article-title":"Effect of dapagliflozin on atrial fibrillation in patients with type 2 diabetes mellitus: insights from the DECLARE-TIMI 58 trial","volume":"141","author":"Zelniker","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib25","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1161\/CIRCULATIONAHA.120.050991","article-title":"Ablation versus drug therapy for atrial fibrillation in heart failure: results from the CABANA trial","volume":"143","author":"Packer","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jchf.2026.102947_bib26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.amjcard.2020.09.035","article-title":"Catheter ablation for atrial fibrillation in patients with concurrent heart failure","volume":"137","author":"Arora","year":"2020","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jchf.2026.102947_bib27","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jchf.2023.01.008","article-title":"Atrial fibrillation ablation for heart failure with preserved ejection fraction: a randomized controlled trial","volume":"11","author":"Chieng","year":"2023","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.jchf.2026.102947_bib28","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/ejhf.3373","article-title":"Catheter-based ablation to improve outcomes in patients with atrial fibrillation and heart failure with preserved ejection fraction: Rationale and design of the CABA-HFPEF-DZHK27 trial","volume":"26","author":"Parwani","year":"2024","journal-title":"Eur J Heart Fail"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926000466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926000466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:43:35Z","timestamp":1792093415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177926000466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2213177926000466"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2026.102947","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Progression From Exercise-Induced to Resting Left Atrial Hypertension in HFpEF","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2026.102947","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}],"article-number":"102947"}}