{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T23:31:20Z","timestamp":1794439880215,"version":"4.9.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jchf.2026.103062","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:04:35Z","timestamp":1777662275000},"page":"103062","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fluid Management of Acute Heart Failure With the Reprieve System"],"prefix":"10.1016","volume":"14","author":[{"given":"James E.","family":"Udelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Javaheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marat","family":"Fudim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0190-2228","authenticated-orcid":false,"given":"Kevin","family":"Damman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9977-7722","authenticated-orcid":false,"given":"Jan","family":"Biegus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aasim","family":"Afzal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alpesh N.","family":"Amin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Bensimhon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason J.","family":"Bischof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene S.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8376-8709","authenticated-orcid":false,"given":"Robert L.","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2199-4078","authenticated-orcid":false,"given":"Simon A.","family":"Mahler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Ponikowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veena","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Ivey-Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Testani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.jchf.2026.103062_bib1","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.jacc.2019.08.001","article-title":"2019 ACC expert consensus decision pathway on risk assessment, management, and clinical trajectory of patients hospitalized with heart failure: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"74","author":"Hollenberg","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.jchf.2026.103062_bib2","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1002\/ejhf.1492","article-title":"Acute heart failure congestion and perfusion status\u2014impact of the clinical classification on in-hospital and long-term outcomes; insights from the ESC-EORP-HFA Heart Failure Long-Term Registry","volume":"21","author":"Chioncel","year":"2019","journal-title":"Eur J Heart Fail"},{"issue":"8","key":"10.1016\/j.jchf.2026.103062_bib3","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.jchf.2024.04.002","article-title":"Contemporary decongestion strategies in patients hospitalized for heart failure: a national community-based cohort study","volume":"12","author":"Zheng","year":"2024","journal-title":"JACC Heart Fail"},{"issue":"11","key":"10.1016\/j.jchf.2026.103062_bib4","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.jchf.2020.05.013","article-title":"In-hospital therapy for heart failure with reduced ejection fraction in the United States","volume":"8","author":"Greene","year":"2020","journal-title":"JACC Heart Fail"},{"issue":"12","key":"10.1016\/j.jchf.2026.103062_bib5","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1038\/s41569-025-01152-z","article-title":"Decongestion in heart failure: medical and device therapies","volume":"22","author":"Cox","year":"2025","journal-title":"Nat Rev Cardiol"},{"issue":"7","key":"10.1016\/j.jchf.2026.103062_bib6","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.cardfail.2025.02.002","article-title":"Reprieve System for the treatment of patients with acute decompensated heart failure","volume":"31","author":"Ivey-Miranda","year":"2025","journal-title":"J Card Fail"},{"issue":"11","key":"10.1016\/j.jchf.2026.103062_bib7","doi-asserted-by":"crossref","first-page":"e1163","DOI":"10.1097\/CCM.0000000000005174","article-title":"Simultaneous use of hypertonic saline and IV furosemide for fluid overload: a systematic review and meta-analysis","volume":"49","author":"Liu","year":"2021","journal-title":"Crit Care Med"},{"issue":"3","key":"10.1016\/j.jchf.2026.103062_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jchf.2019.10.012","article-title":"Real world use of hypertonic saline in refractory acute decompensated heart failure: a U.S. center\u2019s experience","volume":"8","author":"Griffin","year":"2020","journal-title":"JACC Heart Fail"},{"issue":"11","key":"10.1016\/j.jchf.2026.103062_bib9","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1002\/ejhf.3708","article-title":"Sodium chloride versus glucose solute as a volume replacement therapy for more effective decongestion in acute heart failure (SOLVRED-AHF): a prospective, randomized, mechanistic study","volume":"27","author":"Biegus","year":"2025","journal-title":"Eur J Heart Fail"},{"issue":"8","key":"10.1016\/j.jchf.2026.103062_bib10","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003180","article-title":"Hypochloremia and diuretic resistance in heart failure: mechanistic insights","volume":"9","author":"Hanberg","year":"2016","journal-title":"Circ Heart Fail"},{"issue":"8","key":"10.1016\/j.jchf.2026.103062_bib11","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003109","article-title":"Hypochloremia, diuretic resistance, and outcome in patients with acute heart failure","volume":"9","author":"Ter Maaten","year":"2016","journal-title":"Circ Heart Fail"},{"issue":"6","key":"10.1016\/j.jchf.2026.103062_bib12","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1038\/ki.1996.255","article-title":"Whys and wherefores of juxtaglomerular apparatus function","volume":"49","author":"Briggs","year":"1996","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.jchf.2026.103062_bib13","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/sj.ki.5001634","article-title":"WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron","volume":"70","author":"Subramanya","year":"2006","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.jchf.2026.103062_bib14","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1681\/ASN.2010080827","article-title":"The WNK kinase network regulating sodium, potassium, and blood pressure","volume":"22","author":"Hoorn","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"5","key":"10.1016\/j.jchf.2026.103062_bib15","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/eurheartj\/ehac689","article-title":"Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial","volume":"44","author":"Trulls","year":"2023","journal-title":"Eur Heart J"},{"issue":"13","key":"10.1016\/j.jchf.2026.103062_bib16","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1056\/NEJMoa2203094","article-title":"Acetazolamide in acute decompensated heart failure with volume overload","volume":"387","author":"Mullens","year":"2022","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jchf.2026.103062_bib17","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMoa1005419","article-title":"Diuretic strategies in patients with acute decompensated heart failure","volume":"364","author":"Felker","year":"2011","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.jchf.2026.103062_bib18","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1038\/s41591-023-02532-z","article-title":"Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial","volume":"29","author":"Ter Maaten","year":"2023","journal-title":"Nat Med"},{"issue":"36","key":"10.1016\/j.jchf.2026.103062_bib19","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.jchf.2026.103062_bib21","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/ki.1984.153","article-title":"Bumetanide and furosemide in heart failure","volume":"26","author":"Brater","year":"1984","journal-title":"Kidney Int"},{"issue":"1","key":"10.1016\/j.jchf.2026.103062_bib22","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1681\/ASN.0000000000000481","article-title":"Mechanistic differences between torsemide and furosemide","volume":"36","author":"Rao","year":"2024","journal-title":"J Am Soc Nephrol"},{"issue":"19","key":"10.1016\/j.jchf.2026.103062_bib23","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa2102953","article-title":"New creatinine- and cystatin C-based equations to estimate GFR without race","volume":"385","author":"Inker","year":"2021","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.jchf.2026.103062_bib24","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1681\/ASN.2016111178","article-title":"Compensatory distal reabsorption drives diuretic resistance in human heart failure","volume":"28","author":"Rao","year":"2017","journal-title":"J Am Soc Nephrol"},{"issue":"10367","key":"10.1016\/j.jchf.2026.103062_bib25","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/S0140-6736(22)02076-1","article-title":"Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial","volume":"400","author":"Mebazaa","year":"2022","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jchf.2026.103062_bib26","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jchf.2024.08.004","article-title":"Inpatient use of guideline-directed medical therapy during heart failure hospitalizations among community-based health systems","volume":"13","author":"Zheng","year":"2025","journal-title":"JACC Heart Fail"},{"issue":"12","key":"10.1016\/j.jchf.2026.103062_bib27","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1002\/ejhf.3074","article-title":"Early changes in renal function during rapid up-titration of guideline-directed medical therapy following an admission for acute heart failure","volume":"25","author":"Ter Maaten","year":"2023","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"10.1016\/j.jchf.2026.103062_bib28","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.004675","article-title":"Initiation, continuation, or withdrawal of angiotensin-converting enzyme inhibitors\/angiotensin receptor blockers and outcomes in patients hospitalized with heart failure with reduced ejection fraction","volume":"6","author":"Gilstrap","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"19","key":"10.1016\/j.jchf.2026.103062_bib29","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1161\/CIRCULATIONAHA.117.030112","article-title":"Worsening renal function in patients with acute heart failure undergoing aggressive diuresis is not associated with tubular injury","volume":"137","author":"Ahmad","year":"2018","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jchf.2026.103062_bib30","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/ejhf.1697","article-title":"Evaluation of kidney function throughout the heart failure trajectory\u2014a position statement from the Heart Failure Association of the European Society of Cardiology","volume":"22","author":"Mullens","year":"2020","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"10.1016\/j.jchf.2026.103062_bib31","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/CIRCHEARTFAILURE.113.000895","article-title":"Loop diuretic efficiency: a metric of diuretic responsiveness with prognostic importance in acute decompensated heart failure","volume":"7","author":"Testani","year":"2014","journal-title":"Circ Heart Fail"},{"issue":"3","key":"10.1016\/j.jchf.2026.103062_bib32","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/ejhf.3131","article-title":"Sodium loading in ambulatory patients with heart failure with reduced ejection fraction: mechanistic insights into sodium handling","volume":"26","author":"Dauw","year":"2024","journal-title":"Eur J Heart Fail"},{"issue":"5","key":"10.1016\/j.jchf.2026.103062_bib33","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jchf.2019.01.007","article-title":"Natriuretic response is highly variable and associated with 6-month survival: insights from the ROSE-AHF trial","volume":"7","author":"Hodson","year":"2019","journal-title":"JACC Heart Fail"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926001617?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926001617?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:41:36Z","timestamp":1785782496000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177926001617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2213177926001617"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2026.103062","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fluid Management of Acute Heart Failure With the Reprieve System","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2026.103062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"103062"}}