{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:23:00Z","timestamp":1787930580612,"version":"build-2784847793"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Heart Failure"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jchf.2026.103290","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:43:59Z","timestamp":1787928239000},"page":"103290","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Significance of Low Alanine Aminotransferase in Transthyretin Amyloid Cardiomyopathy"],"prefix":"10.1016","author":[{"given":"Chern Hsiang","family":"Choy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tunde","family":"Ogunsakin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanat","family":"Baig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Pinney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5074-2078","authenticated-orcid":false,"given":"Marianna","family":"Fontana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian D.","family":"Gillmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5687-2535","authenticated-orcid":false,"given":"Richard P.","family":"Steeds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William E.","family":"Moody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6 Pt 1","key":"10.1016\/j.jchf.2026.103290_bib1","article-title":"Cardiac amyloidosis in older adults with a focus on frailty: JACC: Advances expert consensus","volume":"4","author":"Bart","year":"2025","journal-title":"JACC Adv"},{"issue":"3","key":"10.1016\/j.jchf.2026.103290_bib2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jaccao.2025.01.018","article-title":"Clinical phenotype and prognostic significance of frailty in transthyretin cardiac amyloidosis","volume":"7","author":"Fumagalli","year":"2025","journal-title":"JACC CardioOncol"},{"issue":"10","key":"10.1016\/j.jchf.2026.103290_bib3","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.3390\/jcm9103185","article-title":"Low ALT levels associated with poor outcomes in 8700 hospitalized heart failure patients","volume":"9","author":"Segev","year":"2020","journal-title":"J Clin Med"},{"issue":"4","key":"10.1016\/j.jchf.2026.103290_bib4","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.jcin.2025.12.001","article-title":"Prognostic value of low alanine aminotransferase in patients undergoing transcatheter aortic valve replacement","volume":"19","author":"Itelman","year":"2026","journal-title":"JACC Cardiovasc Interv"},{"issue":"6","key":"10.1016\/j.jchf.2026.103290_bib5","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.008105","article-title":"Prevalence and prognostic significance of frailty among patients with transthyretin amyloidosis cardiomyopathy","volume":"14","author":"Fine","year":"2021","journal-title":"Circ Heart Fail"}],"container-title":["JACC: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926003914?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213177926003914?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:44:00Z","timestamp":1787928240000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213177926003914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":5,"alternative-id":["S2213177926003914"],"URL":"https:\/\/doi.org\/10.1016\/j.jchf.2026.103290","relation":{},"ISSN":["2213-1779"],"issn-type":[{"value":"2213-1779","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Significance of Low Alanine Aminotransferase in Transthyretin Amyloid Cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"JACC: Heart Failure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchf.2026.103290","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"103290"}}