{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T11:18:14Z","timestamp":1770895094273,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.jchromb.2008.04.041","type":"journal-article","created":{"date-parts":[[2008,5,9]],"date-time":"2008-05-09T10:03:25Z","timestamp":1210327405000},"page":"8-16","source":"Crossref","is-referenced-by-count":54,"title":["Validated LC\u2013MS\/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine"],"prefix":"10.1016","volume":"870","author":[{"given":"Marc","family":"De Meulder","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart M.M.","family":"Remmerie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc L.A.","family":"Sips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Boom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin W.J.","family":"Hooijschuur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nico C.","family":"van de Merbel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip M.M.B.L.","family":"Timmerman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2008.04.041_bib1","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/clpt.1993.146","volume":"54","author":"Huang","year":"1993","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2008.04.041_bib2","first-page":"1134","volume":"21","author":"Mannens","year":"1994","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jchromb.2008.04.041_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF02245439","volume":"114","author":"Megens","year":"1994","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.jchromb.2008.04.041_bib4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02245606","volume":"124","author":"Schotte","year":"1996","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.jchromb.2008.04.041_bib5","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.schres.2006.09.012","volume":"90","author":"Kane","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.jchromb.2008.04.041_bib6","first-page":"241","volume":"vol. 20","author":"Woestenborghs","year":"1990"},{"key":"10.1016\/j.jchromb.2008.04.041_bib7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0378-4347(92)80556-6","volume":"583","author":"Woestenborghs","year":"1992","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.jchromb.2008.04.041_bib8","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0378-4347(00)00323-6","volume":"746","author":"Avenoso","year":"2000","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2008.04.041_bib9","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/1096-9888(200006)35:6<718::AID-JMS999>3.0.CO;2-O","volume":"35","author":"Aravagiri","year":"2000","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.jchromb.2008.04.041_bib10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1365\/s10337-005-0506-y","volume":"61","author":"Zhang","year":"2005","journal-title":"Chromatographia"},{"key":"10.1016\/j.jchromb.2008.04.041_bib11","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S1570-0232(02)00715-8","volume":"783","author":"Remmerie","year":"2003","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2008.04.041_bib12","first-page":"1263","volume":"29","author":"Yasui-Furukori","year":"2001","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jchromb.2008.04.041_bib13","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1177\/0091270002239819","volume":"43","author":"Yasui-Furukori","year":"2003","journal-title":"J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2008.04.041_bib14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jchromb.2007.02.007","volume":"852","author":"\u010cabovska","year":"2007","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2008.04.041_bib15","unstructured":"Guidance for Industry, Bioanalytical Method Validation, U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, May 2001."},{"key":"10.1016\/j.jchromb.2008.04.041_bib16","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1023\/A:1007669411738","volume":"17","author":"Shah","year":"2000","journal-title":"Pharm. Res."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157002320800281X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157002320800281X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T22:57:18Z","timestamp":1546037838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S157002320800281X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S157002320800281X"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2008.04.041","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}