{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:46:18Z","timestamp":1792687578528,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100015718","name":"M\u00fcnchner Zentrum f\u00fcr Gesundheitswissenschaften, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01GI0826"],"award-info":[{"award-number":["01GI0826"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.jchromb.2010.11.016","type":"journal-article","created":{"date-parts":[[2010,11,22]],"date-time":"2010-11-22T04:11:39Z","timestamp":1290399099000},"page":"83-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Aqueous normal phase chromatography improves quantification and qualification of homocysteine, cysteine and methionine by liquid chromatography\u2013tandem mass spectrometry"],"prefix":"10.1016","volume":"879","author":[{"given":"Christian","family":"Hellmuth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Koletzko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Peissner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2010.11.016_bib0005","first-page":"480","volume":"25","author":"Pesek","year":"2007","journal-title":"LC\u2013GC N. Am."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0010","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.chroma.2008.07.077","volume":"1204","author":"Pesek","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2010.11.016_bib0015","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1002\/jssc.200900270","volume":"32","author":"Pesek","year":"2009","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0020","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1002\/jssc.200900648","volume":"33","author":"Matyska","year":"2010","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0025","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1002\/jssc.200900568","volume":"32","author":"Pesek","year":"2009","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0065-2571(98)00008-9","volume":"39","author":"House","year":"1999","journal-title":"Adv. Enzyme Regul."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0035","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1146\/annurev.med.49.1.31","volume":"49","author":"Refsum","year":"1998","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0040","doi-asserted-by":"crossref","unstructured":"Homocysteine Studies Collaboration, JAMA 288 (2002) 2015.","DOI":"10.1001\/jama.288.16.2015"},{"key":"10.1016\/j.jchromb.2010.11.016_bib0045","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.metabol.2004.06.003","volume":"53","author":"Hoffer","year":"2004","journal-title":"Metabolism"},{"key":"10.1016\/j.jchromb.2010.11.016_bib0050","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.1016\/j.jchromb.2009.05.002","volume":"877","author":"Rafii","year":"2009","journal-title":"J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci."},{"issue":"Suppl. 9","key":"10.1016\/j.jchromb.2010.11.016_bib0055","first-page":"155","volume":"59","author":"Jakubowski","year":"2008","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0060","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s00018-003-3204-7","volume":"61","author":"Jakubowski","year":"2004","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0065","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/00002480-199901000-00021","volume":"45","author":"House","year":"1999","journal-title":"ASAIO J."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0070","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1016\/j.jchromb.2009.07.024","volume":"877","author":"Tomaiuolo","year":"2009","journal-title":"J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0075","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1046\/j.1365-2362.2001.00857.x","volume":"31","author":"Tallova","year":"2001","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0080","doi-asserted-by":"crossref","first-page":"1726S","DOI":"10.1093\/jn\/136.6.1726S","volume":"136","author":"Selhub","year":"2006","journal-title":"J. Nutr."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0085","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/clinchem\/46.9.1506","volume":"46","author":"Liu","year":"2000","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0090","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0039-9140(03)00173-5","volume":"60","author":"Nekrassova","year":"2003","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2010.11.016_bib0095","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1373\/clinchem.2005.053835","volume":"51","author":"Windelberg","year":"2005","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0100","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1093\/clinchem\/39.9.1764","volume":"39","author":"Ueland","year":"1993","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0105","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ab.2010.04.034","volume":"405","author":"Sikora","year":"2010","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0110","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/clinchem\/45.9.1517","volume":"45","author":"Magera","year":"1999","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0115","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/bmc.735","volume":"21","author":"Huang","year":"2007","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0120","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.clinbiochem.2005.11.009","volume":"39","author":"Kuhn","year":"2006","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0125","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1258\/000456306778904605","volume":"43","author":"Weaving","year":"2006","journal-title":"Ann. Clin. Biochem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0130","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ab.2007.07.026","volume":"371","author":"Rafii","year":"2007","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0135","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00216-008-1953-8","volume":"391","author":"Hempen","year":"2008","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0140","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jchromb.2008.06.003","volume":"870","author":"Li","year":"2008","journal-title":"J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0145","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.clinbiochem.2004.11.007","volume":"38","author":"Taylor","year":"2005","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0150","doi-asserted-by":"crossref","first-page":"D521","DOI":"10.1093\/nar\/gkl923","volume":"35","author":"Wishart","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0155","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/jms.1777","volume":"45","author":"Horai","year":"2010","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0160","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1002\/jssc.200900171","volume":"32","author":"Callahan","year":"2009","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jchromb.2010.11.016_bib0165","series-title":"Practical HPLC Method Development","author":"Snyder","year":"1997"}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023210007154?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023210007154?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:52:37Z","timestamp":1761605557000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023210007154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S1570023210007154"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2010.11.016","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aqueous normal phase chromatography improves quantification and qualification of homocysteine, cysteine and methionine by liquid chromatography\u2013tandem mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2010.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}