{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:45:22Z","timestamp":1780472722811,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.jchromb.2016.06.011","type":"journal-article","created":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T17:20:21Z","timestamp":1465320021000},"page":"120-129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":61,"special_numbering":"C","title":["Validated methods for determination of neurotransmitters and metabolites in rodent brain tissue and extracellular fluid by reversed phase UHPLC\u2013MS\/MS"],"prefix":"10.1016","volume":"1028","author":[{"given":"Marianne Skov-Skov","family":"Bergh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger Lise","family":"Bogen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Lundanes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5se Marit Leere","family":"\u00d8iestad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2016.06.011_bib0005","series-title":"Neuroscience: Exploring the Brain","author":"Bear","year":"2007"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0010","series-title":"Basic Neurochemistry: Molecular, Cellular and Medical Aspects","author":"Siegel","year":"1999"},{"issue":"14","key":"10.1016\/j.jchromb.2016.06.011_bib0015","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.jchromb.2016.06.011_bib0020","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.neubiorev.2005.04.016","article-title":"The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse?","volume":"30","author":"Pierce","year":"2006","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0025","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/clinchem\/37.10.1854","article-title":"Advances in catecholamine and metabolite measurements for diagnosis of pheochromocytoma","volume":"37","author":"Rosano","year":"1991","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0030","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ab.2009.09.015","article-title":"Determination of dansylated monoamine and amino acid neurotransmitters and their metabolites in human plasma by liquid chromatography\u2013electrospray ionization tandem mass spectrometry","volume":"396","author":"Cai","year":"2010","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0035","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jchromb.2015.02.029","article-title":"In vivo study on the neurotransmitters and their metabolites change in depressive disorder rat plasma by ultra high performance liquid chromatography coupled to tandem mass spectrometry","volume":"988","author":"Zhao","year":"2015","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0040","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.talanta.2011.12.048","article-title":"Quantification of monoamine neurotransmitters and melatonin in sea lamprey brain tissues by high performance liquid chromatography\u2013electrospray ionization tandem mass spectrometry","volume":"89","author":"Wang","year":"2012","journal-title":"Talanta"},{"issue":"1","key":"10.1016\/j.jchromb.2016.06.011_bib0045","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.clinbiochem.2010.08.008","article-title":"Recent advances of liquid chromatography\u2013(tandem) mass spectrometry in clinical and forensic toxicology","volume":"44","author":"Peters","year":"2011","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0050","series-title":"Beginners Guide to UPLC: Ultra-Performance Liquid Chromatography","author":"Grumbach","year":"2009"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0055","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.talanta.2013.03.082","article-title":"Quantitative determination of neurotransmitters, metabolites and derivates in microdialysates by UHPLC\u2013tandem mass spectrometry","volume":"114","author":"Santos-Fandila","year":"2013","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0060","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jneumeth.2011.03.023","article-title":"Development and validation of an ultra-high performance liquid chromatography\u2013tandem mass-spectrometry (UHPLC\u2013MS\/MS) method for the simultaneous determination of neurotransmitters in rat brain samples","volume":"198","author":"Gonz\u00e1lez","year":"2011","journal-title":"J. Neurosci. Methods"},{"issue":"1-2","key":"10.1016\/j.jchromb.2016.06.011_bib0065","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.aca.2010.04.051","article-title":"Simultaneous determination of plasma epinephrine and norepinephrine using an integrated strategy of a fully automated protein precipitation technique, reductive ethylation labeling and UPLC\u2013MS\/MS","volume":"670","author":"Ji","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0070","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.talanta.2013.10.027","article-title":"Liquid chromatography\u2013tandem mass spectrometry method for determination of panel of neurotransmitters in cerebrospinal fluid from the rat model for tauopathy","volume":"119","author":"Kovac","year":"2014","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0075","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.jpba.2013.09.022","article-title":"Determination of monoamine and amino acid neurotransmitters and their metabolites in rat brain samples by UFLC\u2013MS\/MS for the study of the sedative-hypnotic effects observed during treatment with S. chinensis","volume":"88","author":"Wei","year":"2014","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"11\u201312","key":"10.1016\/j.jchromb.2016.06.011_bib0080","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jchromb.2011.02.011","article-title":"The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography\u2013electrospray tandem mass spectrometry","volume":"879","author":"Zhu","year":"2011","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0085","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jchromb.2015.05.017","article-title":"Simultaneous determination of amino acid and monoamine neurotransmitters in PC12 cells and rats models of Parkinson\u2019s disease using a sensitizing derivatization reagent by UHPLC\u2013MS\/MS","volume":"995\u2013996","author":"Zhao","year":"2015","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0090","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aca.2013.02.004","article-title":"Microdialysate analysis of monoamine neurotransmitters\u2014a versatile and sensitive LC\u2013MS\/MS method","volume":"771","author":"Greco","year":"2013","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0095","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jchromb.2004.03.069","article-title":"Determination of serotonin, noradrenaline, dopamine and their metabolites in rat brain extracts and microdialysis samples by column liquid chromatography with fluorescence detection following derivatization with benzylamine and 1,2-diphenylethylenediamine","volume":"807","author":"Yoshitake","year":"2004","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0100","doi-asserted-by":"crossref","first-page":"3382","DOI":"10.1016\/j.chroma.2011.02.006","article-title":"Monitoring of dopamine and its metabolites in brain microdialysates: method combining freeze-drying with liquid chromatography\u2013tandem mass spectrometry","volume":"1218","author":"Syslov\u00e1","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0105","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.vascn.2015.06.002","article-title":"Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry","volume":"74","author":"Gott\u00e5s","year":"2015","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0110","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1021\/ac020361s","article-title":"Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC\u2013MS\/MS","volume":"75","author":"Matuszewski","year":"2003","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0115","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.chroma.2014.04.020","article-title":"Evaluation of 13C- and 2H-labeled internal standards for the determination of amphetamines in biological samples, by reversed-phase ultra-high performance liquid chromatography\u2013tandem mass spectrometry","volume":"1344","author":"Berg","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0120","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.neuint.2009.02.006","article-title":"The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals","volume":"55","author":"Bogen","year":"2009","journal-title":"Neurochem. Int."},{"issue":"1","key":"10.1016\/j.jchromb.2016.06.011_bib0125","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-5793(81)80441-3","article-title":"High-sensitivity amino acid analysis: measurement of amino acid neurotransmitter in mouse brain","volume":"132","author":"Chang","year":"1981","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jchromb.2016.06.011_bib0130","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.neuro.2015.08.004","article-title":"Comparative pharmacological evaluation of the cathinone derivatives, mephedrone and methedrone, in mice","volume":"50","author":"Pail","year":"2015","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0135","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/0028-3908(90)90038-S","article-title":"A new and highly sensitive method for measuring 3-methoxytyramine using HPLC with electrochemical detection. Studies with drugs which alter dopamine metabolism in the brain","volume":"29","author":"Heal","year":"1990","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jchromb.2016.06.011_bib0140","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jchromb.2015.05.014","article-title":"Measurement of catecholamines in rat and mini-pig plasma and urine by liquid chromatography\u2013tandem mass spectrometry coupled with solid phase extraction","volume":"997","author":"He","year":"2015","journal-title":"J. Chromatogr. B"},{"issue":"3","key":"10.1016\/j.jchromb.2016.06.011_bib0145","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1046\/j.1471-4159.1994.63030972.x","volume":"63","author":"Karoum","year":"1994","journal-title":"J. Neurochem."},{"issue":"4","key":"10.1016\/j.jchromb.2016.06.011_bib0150","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1111\/j.1476-5381.1994.tb17152.x","article-title":"Regional effects of amphetamine: cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain","volume":"113","author":"Karoum","year":"1994","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.jchromb.2016.06.011_bib0155","first-page":"163","article-title":"Dopamine release in vivo from nigrostriatal, mesolimbic, and mesocortical neurons: utility of 3-methoxytyramine measurements","volume":"40","author":"Wood","year":"1988","journal-title":"Pharmacol. Rev."},{"issue":"10","key":"10.1016\/j.jchromb.2016.06.011_bib0160","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.trac.2008.09.002","article-title":"Quantitative determination of endogenous compounds in biological samples using chromatographic techniques","volume":"27","author":"van de Merbel","year":"2008","journal-title":"TrAC Trends Anal. Chem."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023216303877?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023216303877?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T20:42:03Z","timestamp":1600720923000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023216303877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":32,"alternative-id":["S1570023216303877"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2016.06.011","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Validated methods for determination of neurotransmitters and metabolites in rodent brain tissue and extracellular fluid by reversed phase UHPLC\u2013MS\/MS","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2016.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}