{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:01:13Z","timestamp":1761606073642,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2017R1D1A3B03033910"],"award-info":[{"award-number":["2017R1D1A3B03033910"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002507","name":"Kangwon National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002507","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.jchromb.2018.08.025","type":"journal-article","created":{"date-parts":[[2018,8,25]],"date-time":"2018-08-25T02:08:41Z","timestamp":1535162921000},"page":"154-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["A rapid and sensitive liquid chromatography\/tandem mass spectrometry assay for simultaneous quantitation of disopyramide and its major metabolite, mono-isopropyl-disopyramide, in rat plasma and its application to a pharmacokinetic study"],"prefix":"10.1016","volume":"1096","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9788-0398","authenticated-orcid":false,"given":"Quynh Khoa","family":"Pham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyewon","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5937-2146","authenticated-orcid":false,"given":"Sung-Hoon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2018.08.025_bb0005","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0163-7258(80)90017-0","volume":"9","author":"Dreifus","year":"1980","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0010","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/oxfordjournals.eurheartj.a062243","volume":"8","author":"Rizos","year":"1987","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0015","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1365-2125.1978.tb04605.x","volume":"6","author":"Bryson","year":"1978","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0020","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/BF01059032","volume":"10","author":"Karim","year":"1982","journal-title":"J. Pharmacokinet. Biopharm."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0025","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1365-2125.1982.tb04955.x","volume":"14","author":"Bredesen","year":"1982","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0030","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2125.1987.tb03007.x","volume":"23","author":"Pedersen","year":"1987","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0035","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0014-2999(78)90313-8","volume":"49","author":"Grant","year":"1978","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0040","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1248\/bpb.20.1310","volume":"20","author":"Yoshiyama","year":"1997","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0045","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1021\/js980256r","volume":"88","author":"Hanada","year":"1999","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0050","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1536\/ihj.52.393","volume":"52","author":"Watanabe","year":"2011","journal-title":"Int. Heart J."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0055","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1046\/j.1365-2125.1999.00073.x","volume":"48","author":"Kenworthy","year":"1999","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0060","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0140-6736(02)11203-7","volume":"360","author":"Nebert","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.jchromb.2018.08.025_bb0065","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s40005-017-0376-y","volume":"48","author":"Jonsson-Schmunk","year":"2018","journal-title":"J. Pharm. Investig."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0070","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s40005-017-0315-y","volume":"48","author":"Kim","year":"2018","journal-title":"J. Pharm. Investig."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0075","doi-asserted-by":"crossref","first-page":"623","DOI":"10.3109\/00365518609083723","volume":"46","author":"Angelo","year":"1986","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0080","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0378-4347(00)00255-3","volume":"744","author":"Bortocan","year":"2000","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0085","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0378-4347(00)84425-4","volume":"274","author":"Charette","year":"1983","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0090","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0378-4347(92)80055-U","volume":"574","author":"Del Cont Bernard","year":"1992","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0095","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0378-4347(91)80501-3","volume":"572","author":"Mayer","year":"1991","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0100","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1002\/jps.2600681033","volume":"68","author":"Nygard","year":"1979","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0105","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0378-4347(00)83841-4","volume":"529","author":"Takahashi","year":"1990","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0110","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0021-9673(01)81057-8","volume":"106","author":"Hutsell","year":"1975","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2018.08.025_bb0115","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0378-4347(00)84102-X","volume":"307","author":"Kapil","year":"1984","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0120","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0378-4347(00)81556-X","volume":"164","author":"Aitio","year":"1979","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0125","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0160-5402(83)90069-4","volume":"9","author":"Brien","year":"1983","journal-title":"J. Pharmacol. Methods"},{"key":"10.1016\/j.jchromb.2018.08.025_bb0130","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S0378-4347(00)81123-8","volume":"424","author":"Le Corre","year":"1988","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0135","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2165\/00003088-200241080-00001","volume":"41","author":"Mehvar","year":"2002","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0140","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1046\/j.1365-2125.2003.01909.x","volume":"56","author":"Nakagawa","year":"2003","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jchromb.2018.08.025_bb0145","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3999\/jscpt.41.35","volume":"41","author":"Harada","year":"2009","journal-title":"Jpn. J. Clin. Pharmacol. Ther."},{"author":"US Food and Drug Administration","key":"10.1016\/j.jchromb.2018.08.025_bb0150"},{"author":"US Food and Drug Administration","key":"10.1016\/j.jchromb.2018.08.025_bb0155"},{"key":"10.1016\/j.jchromb.2018.08.025_bb0160","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10337-010-1869-2","volume":"73","author":"Kollipara","year":"2011","journal-title":"Chromatographia"}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023218309048?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023218309048?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:57:10Z","timestamp":1761605830000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023218309048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":32,"alternative-id":["S1570023218309048"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2018.08.025","relation":{},"ISSN":["1570-0232"],"issn-type":[{"type":"print","value":"1570-0232"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A rapid and sensitive liquid chromatography\/tandem mass spectrometry assay for simultaneous quantitation of disopyramide and its major metabolite, mono-isopropyl-disopyramide, in rat plasma and its application to a pharmacokinetic study","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2018.08.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}