{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:02:37Z","timestamp":1790614957923,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T00:00:00Z","timestamp":1547424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministry of Economy and Competitiveness","doi-asserted-by":"publisher","award":["AGL2013-49500-EXP"],"award-info":[{"award-number":["AGL2013-49500-EXP"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministry of Economy and Competitiveness","doi-asserted-by":"publisher","award":["AGL2016-77105-R"],"award-info":[{"award-number":["AGL2016-77105-R"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Union"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.jchromb.2019.01.002","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T02:34:19Z","timestamp":1546482859000},"page":"11-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Dual liquid-liquid extraction followed by LC-MS\/MS method for the simultaneous quantification of melatonin, cortisol, triiodothyronine, thyroxine and testosterone levels in serum: Applications to a photoperiod study in rats"],"prefix":"10.1016","volume":"1108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1589-4556","authenticated-orcid":false,"given":"Cristina","family":"Domenech-Coca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Marin\u00e9-Casad\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Caimari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Llu\u00eds","family":"Arola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep Maria","family":"del Bas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2838-2402","authenticated-orcid":false,"given":"Cinta","family":"Blad\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"Rodriguez-Naranjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2019.01.002_bb0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.plefa.2014.09.005","article-title":"Prostaglandins and n-3 polyunsaturated fatty acids in the regulation of the hypothalamic\u2013pituitary axis","volume":"91","author":"Shewchuk","year":"2014","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0010","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00360-010-0498-2","article-title":"Endocrine mechanisms of seasonal adaptation in small mammals: from early results to present understanding","volume":"180","author":"Scherbarth","year":"2010","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0015","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.pharmthera.2013.01.005","article-title":"Biological rhythms and melatonin in mood disorders and their treatments","volume":"138","author":"Lanfumey","year":"2013","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0020","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1517\/13543784.2012.711314","article-title":"Role of melatonin in mood disorders and the antidepressant effects of agomelatine","volume":"21","author":"Srinivasan","year":"2012","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0025","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1152\/physrev.00030.2013","article-title":"Thyroid hormone regulation of metabolism","volume":"94","author":"Mullur","year":"2014","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0030","doi-asserted-by":"crossref","first-page":"R131","DOI":"10.1530\/JME-17-0308","article-title":"Molecular regulation of follicle-stimulating hormone synthesis, secretion and action","volume":"60","author":"Das","year":"2018","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0035","article-title":"The endocrine system an overview","volume":"22","author":"Hiller-Sturmh\u00f6fel","year":"1998"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0040","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1080\/15321819.2017.1331169","article-title":"Preparation and development of solid phase radioimmunoassay system for determination of cortisol","volume":"38","author":"Sallam","year":"2017","journal-title":"J. Immunoass. Immunochem."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0045","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/bmc.1691","article-title":"Determination of thyroid hormones and their metabolites in tissue using SPE UPLC-tandem MS","volume":"26","author":"Ackermans","year":"2012","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0050","article-title":"Comparison of commercial ELISA assays for quantification of corticosterone in serum","volume":"7","author":"Marie Kinn","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0055","doi-asserted-by":"crossref","first-page":"739","DOI":"10.21873\/invivo.10989","article-title":"Applicability of commercially available ELISA kits for the quantification of faecal immunoreactive corticosterone metabolites in mice","volume":"30","author":"Abelson","year":"2016","journal-title":"In Vivo"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0060","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1021\/ac1026995","article-title":"Determination of six thyroid hormones in the brain and thyroid gland using isotope-dilution liquid chromatography\/tandem mass spectrometry","volume":"83","author":"Kunisue","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0065","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1016\/j.jchromb.2011.07.005","article-title":"Development and evaluation of a liquid chromatography tandem mass spectrometry method for simultaneous determination of salivary melatonin, cortisol and testosterone","volume":"879","author":"Jensen","year":"2011","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0070","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.cca.2015.10.004","article-title":"Salivary cortisol and cortisone by LC\u2013MS\/MS: validation, reference intervals and diagnostic accuracy in Cushing's syndrome","volume":"451 (","author":"Antonelli","year":"2015","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0075","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1080\/19440049.2011.653989","article-title":"Development of an LC-MS\/MS method to quantify sex hormones in bovine milk and influence of pregnancy in their levels","volume":"29","author":"Regal","year":"2012","journal-title":"Food Addit. Contam. Part A."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0080","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0378-4347(98)00182-0","article-title":"High-performance liquid chromatographic analysis of melatonin in human plasma and rabbit serum with on-line column enrichment","volume":"712","author":"Bechgaard","year":"1998","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0085","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1515\/cclm-2012-0276","article-title":"Target analyte quantification by isotope dilution LC-MS\/MS directly referring to internal standard concentrations \u2013 validation for serum cortisol measurement","volume":"51","author":"Maier","year":"2013","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0090","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.chroma.2014.04.032","article-title":"Validated ultra high performance liquid chromatography-tandem mass spectrometry method for quantitative analysis of total and free thyroid hormones in bovine serum","volume":"1345","author":"Kiebooms","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0095","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.steroids.2009.11.004","article-title":"Validation of a total testosterone assay using high-turbulence liquid chromatography tandem mass spectrometry: total and free testosterone reference ranges","volume":"75","author":"Salameh","year":"2010","journal-title":"Steroids"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0100","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12471","article-title":"Environmental and hormonal regulation of epigenetic enzymes in the hypothalamus","volume":"29","author":"Stevenson","year":"2017","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090253","article-title":"Effect of exercise on photoperiod-regulated hypothalamic gene expression and peripheral hormones in the seasonal dwarf hamster Phodopus sungorus","volume":"9","author":"Petri","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0110","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1242\/jeb.159517","article-title":"Melatonin attenuates phenotypic flexibility of energy metabolism in a photoresponsive mammal, the Siberian hamster","volume":"220","author":"Boraty\u0144ski","year":"2017","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0115","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00360-011-0630-y","article-title":"The regulation of food intake in mammalian hibernators: a review","volume":"182","author":"Florant","year":"2012","journal-title":"J. Comp. Physiol. B Biochem. Syst. Environ. Physiol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0120","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.yfrne.2010.12.003","article-title":"Influence of photoperiod on hormones, behavior, and immune function","volume":"32","author":"Walton","year":"2011","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0125","series-title":"Bioanalytical Method Validation","article-title":"Guidance for industry","author":"Food and Drug Administration","year":"2013"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0130","first-page":"1689","article-title":"Pharmacotherapy: a pathophysiologic approach","volume":"53","author":"Fallis","year":"2013","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0135","series-title":"Append. F Guidel. Stand. Method Perform. Requir","author":"Association of analytical communities (AOAC), Official methods of analysis (OMA)","year":"2012"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jim.2010.03.018","article-title":"Development and validation of a high throughput direct radioimmunoassay for the quantitative determination of serum and plasma melatonin (N-acetyl-5-methoxytryptamine) in mice","volume":"358","author":"Welp","year":"2010","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0145","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/jms.2051","article-title":"Quantitation of melatonin and n-acetylserotonin in human plasma by nanoflow LC-MS\/MS and electrospray LC-MS\/MS","volume":"47","author":"Carter","year":"2012","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0150","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1373\/clinchem.2015.243576","article-title":"Candidate reference measurement procedure for the quantification of total serum cortisol with LC-MS\/MS","volume":"62","author":"Hawley","year":"2016","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0155","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.clinbiochem.2010.07.020","article-title":"Thyroid hormone testing by tandem mass spectrometry","volume":"44","author":"Soldin","year":"2011","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0160","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.cca.2012.10.026","article-title":"Implementation of liquid chromatography\/mass spectrometry into the clinical laboratory","volume":"420","author":"Wu","year":"2013","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0165","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.beem.2013.06.007","article-title":"Principles and pitfalls of free hormone measurements","volume":"27","author":"Faix","year":"2013","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0170","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1007\/s00216-010-3705-9","article-title":"Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry","volume":"397","author":"Wang","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0175","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.steroids.2015.10.011","article-title":"Determination of endocrine disruptors and endogenic androgens and estrogens in rat serum by high-performance liquid chromatography-tandem mass spectrometry","volume":"104","author":"Tournier","year":"2015","journal-title":"Steroids"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0180","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0269-7491(01)00340-2","article-title":"Interaction between cadmium exposure and infection with the intestinal parasite Moniliformis moniliformis (Acanthocephala) on the stress hormone levels in rats","volume":"119","author":"Sures","year":"2002","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0185","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/tox.22509","article-title":"Evaluation of hypothalamus-pituitary-thyroid axis function by chronic perchlorate exposure in male rats","volume":"33","author":"Serrano-Nascimento","year":"2018","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0190","doi-asserted-by":"crossref","DOI":"10.1111\/and.12761","article-title":"Quantitative changes in testicular structure and function in rat exposed to mobile phone radiation","volume":"49","author":"\u00c7etkin","year":"2017","journal-title":"Andrologia"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0195","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neulet.2012.01.040","article-title":"Melatonin modulates cytoskeletal organization in the rat brain hippocampus","volume":"511","author":"Jim\u00e9nez-Rubio","year":"2012","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jchromb.2019.01.002_bb0200","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1740-3391-4-6","article-title":"Spontaneous internal desynchronization of locomotor activity and body temperature rhythms from plasma melatonin rhythm in rats exposed to constant dim light","volume":"4","author":"Aguzzi","year":"2006","journal-title":"J. Circadian Rhythms"},{"key":"10.1016\/j.jchromb.2019.01.002_bb0205","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3906\/biy-1506-77","article-title":"Effects of photoperiod variations and alpha-lipoic acid treatment on n cortisol, and oxidative stress levels in the blood of rats","volume":"39","author":"\u00c7EV\u0130K","year":"2015","journal-title":"Turk. J. Biol."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023218307086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023218307086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:45:30Z","timestamp":1565225130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023218307086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":41,"alternative-id":["S1570023218307086"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2019.01.002","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual liquid-liquid extraction followed by LC-MS\/MS method for the simultaneous quantification of melatonin, cortisol, triiodothyronine, thyroxine and testosterone levels in serum: Applications to a photoperiod study in rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2019.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}