{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:35:19Z","timestamp":1767339319055,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.jchromb.2020.122248","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T20:39:14Z","timestamp":1592253554000},"page":"122248","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure"],"prefix":"10.1016","volume":"1152","author":[{"given":"Jin-Ming","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Run","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian-Nan","family":"Di","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao-Wei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2020.122248_b0005","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envpol.2015.08.044","article-title":"Prenatal nonylphenol exposure, oxidative and nitrative stress, and birth outcomes: A cohort study in Taiwan","volume":"207","author":"Wang","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jchromb.2020.122248_b0010","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cbi.2014.07.010","article-title":"Recovery from developmental nonylphenol exposure is possible for female rats","volume":"221","author":"Chang","year":"2014","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jchromb.2020.122248_b0015","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.chemosphere.2009.04.054","article-title":"Association between nonylphenol exposure and development of secondary sexual characteristics","volume":"76","author":"Chen","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.jchromb.2020.122248_b0020","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.scitotenv.2017.07.092","article-title":"Concurrent exposures to nonylphenol, bisphenol A, phthalates, and organophosphate pesticides on birth outcomes: A cohort study in Taipei, Taiwan","volume":"607-608","author":"Huang","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jchromb.2020.122248_b0025","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1080\/09593330.2013.848939","article-title":"Fate of nonylphenol ethoxylate (NPEO) and its inhibitory impact on the biodegradation of acetate under aerobic conditions","volume":"35","author":"Ekdal","year":"2014","journal-title":"Environ. Technol."},{"key":"10.1016\/j.jchromb.2020.122248_b0030","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.envint.2008.01.004","article-title":"Nonylphenol in the environment: A critical review on occurrence, fate, toxicity and treatment in wastewaters","volume":"34","author":"Soares","year":"2008","journal-title":"Environ. Int."},{"issue":"2015","key":"10.1016\/j.jchromb.2020.122248_b0035","first-page":"320","article-title":"Bisphenol A and nonylphenol in foodstuffs: Chinese dietary exposure from the 2007 total diet study and infant health risk from formulas","volume":"167","author":"Niu","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.jchromb.2020.122248_b0040","doi-asserted-by":"crossref","first-page":"571","DOI":"10.2116\/bunsekikagaku.48.571","article-title":"Concentration of bisphenol A and nonylphenol by solid-phase extraction and direct analysis by LC MS","volume":"48","author":"Yonekubo","year":"1999","journal-title":"Bunseki Kagaku"},{"key":"10.1016\/j.jchromb.2020.122248_b0045","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.envint.2007.04.008","article-title":"Daily intake of 4-nonylphenol in Taiwanese","volume":"33","author":"Lu","year":"2007","journal-title":"Environ. Int."},{"issue":"2","key":"10.1016\/j.jchromb.2020.122248_b0050","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s00216-005-0181-8","article-title":"Estrogen-active nonylphenols from an isomer-specific viewpoint: a systematic numbering system and future trends","volume":"384","author":"Guenther","year":"2005","journal-title":"Anal. Bioanal. Chem."},{"issue":"3","key":"10.1016\/j.jchromb.2020.122248_b0055","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/fsn3.404","article-title":"Migration of nonylphenol and plasticizers from polyvinyl chloride stretch film into food simulants, rapeseed oil, and foods","volume":"5","author":"Kawamura","year":"2017","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.jchromb.2020.122248_b0060","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.chroma.2017.12.011","article-title":"Determination of of household and industrial chemicals, personal care products and hormones in leafy and root vegetables by liquid chromatography-tandem mass spectrometry","volume":"1533","author":"Aparicio","year":"2018","journal-title":"J. Chromatogr. A"},{"issue":"8","key":"10.1016\/j.jchromb.2020.122248_b0065","doi-asserted-by":"crossref","first-page":"5711","DOI":"10.1007\/s11356-014-3974-5","article-title":"Bisphenol A, nonylphenols, benzophenones, and benzotriazoles in soils, groundwater, surface water, sediments, and food: a review","volume":"22","author":"Careghini","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"1-3","key":"10.1016\/j.jchromb.2020.122248_b0070","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.tox.2012.06.017","article-title":"In utero and neonate exposure to nonylphenol develops hyperadrenalism and metabolic syndrome later in life. I. First generation rats (F1)","volume":"301","author":"Chang","year":"2012","journal-title":"Toxicology"},{"issue":"11","key":"10.1016\/j.jchromb.2020.122248_b0075","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.chemosphere.2010.11.065","article-title":"Endocrine disrupting nonyl- and octylphenol in infant food in Germany: Considerable daily intake of nonylphenol for babies","volume":"82","author":"Raecker","year":"2011","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.jchromb.2020.122248_b0080","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1039\/b211323f","article-title":"Dietary exposure to xenoestrogens in New Zealand","volume":"5","author":"Thomson","year":"2003","journal-title":"J. Environ. Monitor."},{"key":"10.1016\/j.jchromb.2020.122248_b0085","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.taap.2018.04.007","article-title":"Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats","volume":"348","author":"Di","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jchromb.2020.122248_b0090","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.etap.2017.02.024","article-title":"Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems","volume":"51","author":"Sifakis","year":"2017","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"7","key":"10.1016\/j.jchromb.2020.122248_b0095","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.tiv.2015.04.022","article-title":"4-Nonylphenol reduces cell viability and induces apoptosis and ER-stress in a human epithelial intestinal cell line","volume":"29","author":"Lepretti","year":"2015","journal-title":"Toxicol. In Vitro"},{"issue":"3","key":"10.1016\/j.jchromb.2020.122248_b0100","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.taap.2012.02.016","article-title":"Potential hazards to embryo implantation: A human endometrial in vitro model to identify unwanted antigestagenic actions of chemicals","volume":"260","author":"Fischer","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"11","key":"10.1016\/j.jchromb.2020.122248_b0105","doi-asserted-by":"crossref","first-page":"e79838","DOI":"10.1371\/journal.pone.0079838","article-title":"Measurement of Phenolic Environmental Estrogens in Women with Uterine Leiomyoma","volume":"8","author":"Shen","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jchromb.2020.122248_b0110","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ijgo.2015.04.051","article-title":"Prevalence, morbidity, and current medical management of uterine leiomyomas","volume":"131","author":"Drayer","year":"2015","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.jchromb.2020.122248_b0115","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/AOG.0000000000001160","article-title":"Association between patient characteristics and treatment procedure among patients with uterine leiomyomas","volume":"127","author":"Borah","year":"2016","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.jchromb.2020.122248_b0120","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1055\/s-0030-1251477","article-title":"New directions in the epidemiology of uterine fibroids","volume":"28","author":"Laughlin","year":"2010","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.jchromb.2020.122248_b0125","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jsgi.2005.12.001","article-title":"Luteinizing hormone in premenopausal women may stimulate uterine leiomyomata development","volume":"13","author":"Baird","year":"2006","journal-title":"J. Soc. Gynecol. Invest."},{"key":"10.1016\/j.jchromb.2020.122248_b0130","doi-asserted-by":"crossref","first-page":"379","DOI":"10.12717\/DR.2018.22.4.379","article-title":"Chronic low-dose nonylphenol or di-(2-ethylhexyl) phthalate has a different estrogen-like response in mouse uterus","volume":"22","author":"Kim","year":"2018","journal-title":"Dev. Reprod."},{"key":"10.1016\/j.jchromb.2020.122248_b0135","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jchromb.2013.08.032","article-title":"Measurement of phenolic environmental estrogens in human urine samples by HPLC-MS\/MS and primary discussion the possible linkage with uterine leiomyoma","volume":"938","author":"Zhou","year":"2013","journal-title":"J. Chromatogr. B Analyt. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jchromb.2020.122248_b0140","first-page":"40","article-title":"A study on bisphenol a, nonylphenol, and octylphenol in human urine amples detected by SPE-UPLC-MS","volume":"24","author":"Xiao","year":"2011","journal-title":"Biomed. Environ. Sci."},{"issue":"8","key":"10.1016\/j.jchromb.2020.122248_b0145","doi-asserted-by":"crossref","first-page":"932","DOI":"10.3390\/ijerph14080932","article-title":"Urinary levels of 4-nonylphenol and 4-t-octylphenol in a representative sample of the korean adult population","volume":"14","author":"Park","year":"2017","journal-title":"IJERPH"},{"key":"10.1016\/j.jchromb.2020.122248_b0150","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/aje\/kwt250","article-title":"Prenatal diethylstilbestrol exposure and risk of uterine leiomyomata in the Nurses' Health Study II","volume":"179","author":"Mahalingaiah","year":"2014","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.jchromb.2020.122248_b0155","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/mc.20308","article-title":"Developmental exposure to diethylstilbestrol alters uterine gene expression that may be associated with uterine neoplasia later in life","volume":"46","author":"Newbold","year":"2007","journal-title":"Mol. Carcinog."},{"key":"10.1016\/j.jchromb.2020.122248_b0160","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1289\/ehp.1103620","article-title":"Early-life exposures and early-onset uterine leiomyomata in black women in the sister study","volume":"120","author":"D'Aloisio","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.jchromb.2020.122248_b0165","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.envres.2014.06.028","article-title":"Bisphenol A, benzophenone-type ultraviolet filters, and phthalates in relation to uterine leiomyoma","volume":"137","author":"Pollack","year":"2015","journal-title":"Environ. Res."},{"issue":"211","key":"10.1016\/j.jchromb.2020.122248_b0170","first-page":"e211","article-title":"The estimated annual cost of uterine leiomyomata in the United States","volume":"206","author":"Cardozo","year":"2012","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.jchromb.2020.122248_b0175","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1071\/RD10339","article-title":"Enhancement of lipid metabolism with L-carnitine during in vitro maturation improves nuclear maturation and cleavage ability of follicular porcine oocytes","volume":"23","author":"Somfai","year":"2011","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.jchromb.2020.122248_b0180","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1093\/humrep\/deu201","article-title":"L-carnitine supplementation during vitrification of mouse germinal vesicle stage-oocytes and their subsequent in vitro maturation improves meiotic spindle configuration and mitochondrial distribution in metaphase II oocytes","volume":"29","author":"Moawad","year":"2014","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.jchromb.2020.122248_b0185","first-page":"77","article-title":"Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality","volume":"10","author":"Aliabadi","year":"2012","journal-title":"Iran. J. Reprod. Med."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023220302063?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023220302063?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:01:20Z","timestamp":1761606080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023220302063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":37,"alternative-id":["S1570023220302063"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2020.122248","relation":{},"ISSN":["1570-0232"],"issn-type":[{"type":"print","value":"1570-0232"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2020.122248","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"122248"}}