{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:11:56Z","timestamp":1778623916957,"version":"3.51.4"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003443","name":"Ministry of Education and Science of the Russian Federation","doi-asserted-by":"publisher","award":["075-15-2020-926"],"award-info":[{"award-number":["075-15-2020-926"]}],"id":[{"id":"10.13039\/501100003443","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007052","name":"Universit\u00e0 degli Studi di Verona","doi-asserted-by":"publisher","award":["CUPB36J17000000003"],"award-info":[{"award-number":["CUPB36J17000000003"]}],"id":[{"id":"10.13039\/501100007052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.jchromb.2021.122942","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T11:20:05Z","timestamp":1631877605000},"page":"122942","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A novel high-throughput liquid chromatography assay for Carbohydrate-Deficient transferrin (CDT) based on flow-modulated isocratic elution and terbium-induced fluorescence"],"prefix":"10.1016","volume":"1182","author":[{"given":"Giacomo","family":"Musile","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elio","family":"Franco De Palo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romolo","family":"Marco Dorizzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kseniia","family":"Shestakova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Appolonova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Tagliaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jchromb.2021.122942_b0005","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/jssc.201700914","article-title":"Monitoring of transferrin isoforms in biological samples by capillary electrophoresis","volume":"41","author":"Caslavska","year":"2018","journal-title":"J. Sep. Sci."},{"issue":"5","key":"10.1016\/j.jchromb.2021.122942_b0010","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1530-0277.1986.tb05138.x","article-title":"Micro Anion Exchange Chromatography of Carbohydrate-Deficient Transferrin in Serum in Relation to Alcohol Consumption (Swedish Patent8400587\u20135)","volume":"10","author":"Stibler","year":"1986","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.jchromb.2021.122942_b0015","first-page":"55","article-title":"Biomarkers for the Identification of Alcohol Use\/Abuse: A Critical Review","volume":"23","author":"Bortolotti","year":"2011","journal-title":"Forensic Sci Rev."},{"key":"10.1016\/j.jchromb.2021.122942_b0020","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jpba.2017.09.006","article-title":"Analytical and diagnostic aspects of carbohydrate deficient transferrin (CDT): A critical review over years 2007\u20132017","volume":"147","author":"Bortolotti","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jchromb.2021.122942_b0025","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1373\/clinchem.2014.221531","article-title":"Harmonization of measurement results of the alcohol biomarker carbohydrate-deficient transferrin by use of the toolbox of technical procedures of the international Consortium for harmonization of Clinical Laboratory results","volume":"7","author":"Weykamp","year":"2014","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2021.122942_b0030","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.forsciint.2014.03.014","article-title":"New insights in carbohydrate-deficient transferrin analysis with capillary electrophoresis-mass spectrometry","volume":"243","author":"Kohler","year":"2014","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jchromb.2021.122942_b0035","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1373\/clinchem.2017.285452","article-title":"Detection and Quantification of Carbohydrate-Deficient Transferrin by MALDI-Compatible Protein Chips Prepared by Ambient Ion Soft Landing","volume":"64","author":"Darebna","year":"2018","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2021.122942_b0040","unstructured":"E.F. De Palo, F. Tagliaro, D. Sorio, F. Bortolotti, Analytical method for the identification of at least one glycoform of the transferrin protein, WO 2015\/135900 A1, 2015."},{"issue":"5","key":"10.1016\/j.jchromb.2021.122942_b0045","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1007\/s00216-016-0069-9","article-title":"Fluorescent adduct formation with terbium: a novel strategy for transferrin glycoform identification in human body fluids and carbohydrate-deficient transferrin HPLC method validation","volume":"409","author":"Sorio","year":"2017","journal-title":"Anal. Bioanal. Chem."},{"issue":"28","key":"10.1016\/j.jchromb.2021.122942_b0050","doi-asserted-by":"crossref","first-page":"6605","DOI":"10.1007\/s00216-017-0616-z","article-title":"Terbium chelation, a specific fluorescent tagging of human transferrin. Optimization of conditions in view of its application to the HPLC analysis of carbohydrate-deficient transferrin (CDT)","volume":"409","author":"Nicotra","year":"2017","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jchromb.2021.122942_b0055","unstructured":"Bioanalytical method validation. https:\/\/www.fda.gov\/ downloads\/Drugs\/Guidance\/ucm070107.pdf (Accessed 09 July 2018), (n.d.)."},{"issue":"10","key":"10.1016\/j.jchromb.2021.122942_b0060","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1093\/clinchem\/39.10.2115","article-title":"Carbohydrate-deficient transferrin quantified by HPLC to determine heavy consumption of alcohol","volume":"39","author":"Jeppsson","year":"1993","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2021.122942_b0065","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.cca.2019.06.003","article-title":"A novel low-cost approach for the semi-quantitative analysis of carbohydrate-deficient transferrin (CDT) based on fluorescence resonance energy transfer (FRET)","volume":"495","author":"Musile","year":"2019","journal-title":"Clin. Chim. Acta."},{"key":"10.1016\/j.jchromb.2021.122942_b0070","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1373\/clinchem.2003.023341","article-title":"Improved HPLC Method for Carbohydrate-deficient Transferrin in Serum","volume":"49","author":"Helander","year":"2003","journal-title":"Clin. Chem."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023221004232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023221004232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:19:49Z","timestamp":1778620789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023221004232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":14,"alternative-id":["S1570023221004232"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2021.122942","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel high-throughput liquid chromatography assay for Carbohydrate-Deficient transferrin (CDT) based on flow-modulated isocratic elution and terbium-induced fluorescence","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2021.122942","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"122942"}}