{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T22:17:14Z","timestamp":1774563434199,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.jchromb.2022.123204","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T17:00:24Z","timestamp":1646240424000},"page":"123204","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Development and validation of a novel evaporation setup-assisted TLC method with fluorescence detection for determination of flibanserin in pharmaceutical and biological samples"],"prefix":"10.1016","volume":"1195","author":[{"given":"Noha M.","family":"Hosny","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Abdelkarim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed I.","family":"Gadallah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba","family":"Salah Mousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jchromb.2022.123204_b0005","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1056\/NEJMp1513686","article-title":"FDA approval of flibanserin\u2014treating hypoactive sexual desire disorder","volume":"374","author":"Joffe","year":"2016","journal-title":"New England Journal of Medicine."},{"issue":"1","key":"10.1016\/j.jchromb.2022.123204_b0010","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1743-6109.2010.02032.x","article-title":"Multifunctional pharmacology of flibanserin: possible mechanism of therapeutic action in hypoactive sexual desire disorder","volume":"8","author":"Stahl","year":"2011","journal-title":"The journal of sexual medicine."},{"issue":"8","key":"10.1016\/j.jchromb.2022.123204_b0015","doi-asserted-by":"crossref","DOI":"10.1002\/bmc.4545","article-title":"Development and validation of liquid chromatography\u2013electrospray\u2013tandem mass spectrometry method for determination of flibanserin in human plasma: Application to pharmacokinetic study on healthy female volunteers","volume":"33","author":"Sultan","year":"2019","journal-title":"Biomed. Chromatogr."},{"issue":"14","key":"10.1016\/j.jchromb.2022.123204_b0020","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.4155\/bio-2018-0065","article-title":"A validated UPLC\u2013MS\/MS method for flibanserin in plasma and its pharmacokinetic interaction with bosentan in rats","volume":"10","author":"Iqbal","year":"2018","journal-title":"Bioanalysis."},{"issue":"5","key":"10.1016\/j.jchromb.2022.123204_b0025","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1039\/D0NJ05548D","article-title":"Insights into flibanserin oxidative stress degradation pathway: in silico\u2013in vitro toxicity assessment of its degradates","volume":"45","author":"El-Behairy","year":"2021","journal-title":"New J. Chem."},{"issue":"6","key":"10.1016\/j.jchromb.2022.123204_b0030","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/jat\/bkaa009","article-title":"Mass spectrometry-based rapid quantitative bioanalysis of flibanserin: pharmacokinetic and brain tissue distribution study in female rats","volume":"44","author":"Sharma","year":"2020","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jchromb.2022.123204_b0035","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jpba.2014.01.021","article-title":"Determination of flibanserin and tadalafil in supplements for women sexual desire enhancement using high-performance liquid chromatography with tandem mass spectrometer, diode array detector and charged aerosol detector","volume":"94","author":"Poplawska","year":"2014","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jchromb.2022.123204_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106281","article-title":"A mechanistic explanation on degradation behavior of flibanserin for identification and characterization of its potential degradants using LC-DAD\/ESI\/APCI-Q-TOF-MS\/MS","volume":"167","author":"Sharma","year":"2021","journal-title":"Microchem. J."},{"key":"10.1016\/j.jchromb.2022.123204_b0045","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1039\/9781839160783-00330","article-title":"A Novel LC-ESI-MS\/MS Method for the Quantification of Flibanserin in Bulk and Pharmaceutical Formulations","volume":"355","author":"Kowmudi","year":"2019","journal-title":"Conference on Drug Design and Discovery Technologies, RSC."},{"issue":"1","key":"10.1016\/j.jchromb.2022.123204_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13065-019-0620-9","article-title":"A rapid and sensitive UPLC-MS\/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study","volume":"13","author":"He","year":"2019","journal-title":"BMC chemistry."},{"issue":"4","key":"10.1016\/j.jchromb.2022.123204_b0055","first-page":"501","article-title":"Reverse Phase High Performance Liquid Chromatography Method Development and Validation for Estimation of Flibanserin in Bulk and Dosage Form","volume":"11","author":"Manjaramkar","year":"2020","journal-title":"Journal of Pharmaceutical Quality Assurance"},{"key":"10.1016\/j.jchromb.2022.123204_b0060","article-title":"Amalgamation of stress degradation and metabolite profiling in rat urine and feces for characterization of oxidative metabolites of flibanserin using UHPLC-Q-TOF-MS\/MS","volume":"1139","author":"Sharma","year":"2020","journal-title":"H\/D exchange and NMR technique, Journal of Chromatography B."},{"issue":"4","key":"10.1016\/j.jchromb.2022.123204_b0065","doi-asserted-by":"crossref","first-page":"40","DOI":"10.53879\/id.57.04.12147","article-title":"Article Details New Stability Indicating Method for Estimation of Purity of Flibanserin Active Pharmaceutical Ingredient","volume":"57","author":"Yik-Ling","year":"2020","journal-title":"Indian Drugs"},{"issue":"7","key":"10.1016\/j.jchromb.2022.123204_b0070","first-page":"783","article-title":"Detection of Avanafil and Flibanserin in Health Food by HPLC-MS\/MS, Herald of","volume":"36","author":"Yuanyang","year":"2017","journal-title":"Medicine"},{"key":"10.1016\/j.jchromb.2022.123204_b0075","unstructured":"H. Tian, H. Wang, Determination of Content and Related Substances of Flibanserin by HPLC-DAD, China Pharmacist. 20(10) (2017) 1777-1780. http:\/\/wprim.whocc.org.cn\/admin\/article\/articleDetail?WPRIMID=658131&articleId=658131."},{"issue":"23","key":"10.1016\/j.jchromb.2022.123204_b0080","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1039\/D0AY00741B","article-title":"Surface-enhanced Raman spectroscopy for rapid identification and quantification of Flibanserin in different kinds of wine","volume":"12","author":"Bao","year":"2020","journal-title":"Anal. Methods"},{"key":"10.1016\/j.jchromb.2022.123204_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2019.127042","article-title":"Four solid forms of flibanserin: Insight into the crystal structures, properties, stability, and solid-state transition","volume":"1199","author":"Qi","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.jchromb.2022.123204_b0090","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jpba.2011.08.027","article-title":"Isolation and structural elucidation of flibanserin as an adulterant in a health supplement used for female sexual performance enhancement","volume":"57","author":"Low","year":"2012","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"21","key":"10.1016\/j.jchromb.2022.123204_b0095","doi-asserted-by":"crossref","first-page":"4932","DOI":"10.3390\/molecules25214932","article-title":"Development and Greenness Evaluation of Spectrofluorometric Methods for Flibanserin Determination in Dosage Form and Human Urine Samples","volume":"25","author":"Ahmed","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.jchromb.2022.123204_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2019.117491","article-title":"Determination of flibanserin in the presence of confirmed degradation products by a third derivative emission spectrofluorometric method: Application to pharmaceutical formulation","volume":"225","author":"Ahmed","year":"2020","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"issue":"5","key":"10.1016\/j.jchromb.2022.123204_b0105","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1007\/s10812-020-01097-w","article-title":"Univariate and Chemometrics-Assisted Spectrophotometric Methods for Determination of Flibanserin in a Recently Released Dosage Form","volume":"87","author":"Ahmed","year":"2020","journal-title":"J. Appl. Spectrosc."},{"key":"10.1016\/j.jchromb.2022.123204_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106020","article-title":"A novel design and facile synthesis of nature inspired poly (dopamine-Cr3+) nanocubes decorated reduced graphene oxide for electrochemical sensing of flibanserin","volume":"164","author":"Mahnashi","year":"2021","journal-title":"Microchem. J."},{"key":"10.1016\/j.jchromb.2022.123204_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.105960","article-title":"A rapid and sensitive stability-indicating green RP-HPTLC method for the quantitation of flibanserin compared to green NP-HPTLC method: Validation studies and greenness assessment","volume":"164","author":"Foudah","year":"2021","journal-title":"Microchem. J."},{"issue":"2","key":"10.1016\/j.jchromb.2022.123204_b0120","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/prs.11566","article-title":"An experimental investigation of evaporation rates for different volatile organic compounds","volume":"32","author":"Heymes","year":"2013","journal-title":"Process Saf. Prog."},{"key":"10.1016\/j.jchromb.2022.123204_b0125","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.talanta.2017.08.051","article-title":"Innovative thin-layer chromatographic method combined with fluorescence detection for specific determination of Febuxostat: Application in biological fluids","volume":"176","author":"Mohamed","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2022.123204_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106131","article-title":"Innovative TLC-densitometric method with fluorescent detection for simultaneous determination of ternary anti-diabetic mixture in pharmaceutical formulations and human plasma","volume":"165","author":"Abbas","year":"2021","journal-title":"Microchem. J."},{"issue":"3","key":"10.1016\/j.jchromb.2022.123204_b0135","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0160-4120(80)90123-3","article-title":"Evaporation of solutes from water","volume":"3","author":"Chiou","year":"1980","journal-title":"Environ. Int."},{"issue":"6","key":"10.1016\/j.jchromb.2022.123204_b0140","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1007\/s10895-015-1656-4","article-title":"Determination of Some Non-sedating Antihistamines via Their Native Fluorescence and Derivation of Some Quantitative Fluorescence Intensity-Structure Relationships","volume":"25","author":"El-Kommos","year":"2015","journal-title":"Journal of fluorescence."},{"key":"10.1016\/j.jchromb.2022.123204_b0145","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.microc.2019.03.022","article-title":"Facile micelle-enhanced spectrofluorimetric method for picogram level determination of febuxostat; application in tablets and in real human plasma","volume":"147","author":"Atia","year":"2019","journal-title":"Microchem. J."},{"key":"10.1016\/j.jchromb.2022.123204_b0150","doi-asserted-by":"crossref","unstructured":"S.AE.R. Hussein, H.M.A. El-Wadood, M.A.E.W. Abdallah, A.A.E.H. Khorshed, HPTLC with fluorescence densitometry for simultaneous determination of some angiotensin II receptor blockers in tablets and plasma, Journal of AOAC International. 98(2) (2015) 354-360. https:\/\/doi.org\/10.5740\/jaoacint.14-179.","DOI":"10.5740\/jaoacint.14-179"},{"key":"10.1016\/j.jchromb.2022.123204_b0155","unstructured":"ICH Harmonised Tripartite Guideline: Validation of Analytical Procedures: Text and Methodology, Q2 (R1) Geneva, 2005, http:\/\/www.ich.org (accessed 12 Feburary 2021)."},{"key":"10.1016\/j.jchromb.2022.123204_b0160","unstructured":"Guideline on Bioanalytical Method Validation, London, United Kingdom, July 2011, https:\/\/www.ema.europa.eu\/en\/documents\/scientific-guideline\/guideline-bioanalytical-method-validation_en.pdf (accessed 26 September 2021)."}],"updated-by":[{"DOI":"10.1016\/j.jchromb.2022.123479","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000}}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023222001088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023222001088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T09:05:33Z","timestamp":1700298333000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023222001088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":32,"alternative-id":["S1570023222001088"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2022.123204","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jchromb.2022.123479","asserted-by":"object"}]},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and validation of a novel evaporation setup-assisted TLC method with fluorescence detection for determination of flibanserin in pharmaceutical and biological samples","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2022.123204","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"123204"}}