{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:04:10Z","timestamp":1787583850449,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jchromb.2023.123826","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T04:26:20Z","timestamp":1689567980000},"page":"123826","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["HiSorb sorptive extraction for determining salivary short chain fatty acids and hydroxy acids in heart failure patients"],"prefix":"10.1016","volume":"1228","author":[{"given":"Alessio","family":"Lenzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Biagini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Ghimenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico M.","family":"Vivaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Salvo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Di Francesco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1822-7399","authenticated-orcid":false,"given":"Tommaso","family":"Lomonaco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2023.123826_b0005","author":"Aparicio","year":"2021","journal-title":"Heart disease and stroke statistics-2021 update a report from the american heart association"},{"issue":"2021","key":"10.1016\/j.jchromb.2023.123826_b0010","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jchromb.2023.123826_b0015","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.119.006472","article-title":"Risk factors for heart failure: 20-year population-based trends by sex, socioeconomic status, and ethnicity","author":"Lawson","year":"2020","journal-title":"Circ. Hear. Fail."},{"key":"10.1016\/j.jchromb.2023.123826_b0020","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/ejhf.566","article-title":"European society of cardiology heart failure follow-up outcomes and differences across regions","volume":"18","author":"Crespo-Leiro","year":"2016","journal-title":"ESC Hear. Fail."},{"key":"10.1016\/j.jchromb.2023.123826_b0025","first-page":"63","article-title":"Economic burden of hospitalizations of Medicare beneficiaries with heart failure, Risk Manag. Healthc","volume":"10","author":"Kilgore","year":"2017","journal-title":"Policy"},{"key":"10.1016\/j.jchromb.2023.123826_b0030","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1373\/clinchem.2016.263749","article-title":"Specificity of B-type natriuretic peptide assays: Cross-reactivity with different BNP, NT-proBNP, and proBNP peptides","volume":"63","author":"Saenger","year":"2017","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0035","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/ejhf.1792","article-title":"Gut dysbiosis and heart failure: navigating the universe within","volume":"22","author":"Madan","year":"2020","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.jchromb.2023.123826_b0040","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/0022034518805739","article-title":"The oral microbiota is modified by systemic diseases","volume":"98","author":"Graves","year":"2019","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.jchromb.2023.123826_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms21144895","article-title":"Effects of short-chain fatty acids on human oral epithelial cells and the potential impact on periodontal disease: A systematic review of in vitro studies","volume":"21","author":"Magrin","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jchromb.2023.123826_b0050","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1600-0765.2007.01048.x","article-title":"The effect of butyric acid on adhesion molecule expression by human gingival epithelial cells","volume":"43","author":"Takigawa","year":"2008","journal-title":"J. Periodontal Res."},{"key":"10.1016\/j.jchromb.2023.123826_b0055","doi-asserted-by":"crossref","DOI":"10.1080\/20002297.2019.1617014","article-title":"Determining bacterial and host contributions to the human salivary metabolome","volume":"11","author":"Gardner","year":"2019","journal-title":"J. Oral Microbiol."},{"key":"10.1016\/j.jchromb.2023.123826_b0060","article-title":"Lactate physiology in health and disease, Contin. Educ. Anaesthesia, Crit. Care","author":"Phypers","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.jchromb.2023.123826_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115781","article-title":"Saliva sampling: Methods and devices. An overview, TrAC -","volume":"124","author":"Bellagambi","year":"2020","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0070","doi-asserted-by":"crossref","first-page":"4466","DOI":"10.1128\/JVI.03326-13","article-title":"Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote kaposi\u2019s sarcoma-associated herpesvirus replication","volume":"88","author":"Yu","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.jchromb.2023.123826_b0075","unstructured":"F. Orata, Derivatization Reactions and Reagents for Gas Chromatography Analysis, in: 2007."},{"key":"10.1016\/j.jchromb.2023.123826_b0080","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jiec.2019.12.001","article-title":"Chemical derivatization-based LC\u2013MS\/MS method for quantitation of gut microbial short-chain fatty acids","volume":"83","author":"Song","year":"2020","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2022.115148","article-title":"A sensitive and accurate GC\u2013MS method for analyzing microbial metabolites short chain fatty acids and their hydroxylated derivatives in newborn fecal samples","volume":"223","author":"Xia","year":"2023","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jchromb.2023.123826_b0090","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.talanta.2018.12.049","article-title":"A sensitive GC\/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples","volume":"196","author":"Zhang","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2023.123826_b0095","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jchromb.2016.08.015","article-title":"Pentafluorobenzyl bromide \u2014 A versatile derivatization agent in chromatography and mass spectrometry: I. analysis of inorganic anions and organophosphates","volume":"1043","author":"Tsikas","year":"2017","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jchromb.2023.123826_b0100","unstructured":"Markes International Ltd, HiSorb sorptive extraction: brochure, (n.d.)."},{"key":"10.1016\/j.jchromb.2023.123826_b0105","unstructured":"Markes International Ltd, Introducing HiSorb Sorptive Extraction, (2016)."},{"key":"10.1016\/j.jchromb.2023.123826_b0110","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0014-3057(78)90084-8","article-title":"The thermal degradation of polysiloxanes-I. Poly(dimethylsiloxane)","volume":"14","author":"Grassie","year":"1978","journal-title":"Eur. Polym. J."},{"key":"10.1016\/j.jchromb.2023.123826_b0115","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1021\/ac9606362","article-title":"Derivatization\/Solid-Phase Microextraction: New approach to polar analytes","volume":"69","author":"Pan","year":"1997","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0120","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1351\/pac200274050835","article-title":"Harmonized guidelines for single-laboratory validation of methods of analysis (IUPAC Technical Report)","volume":"74","author":"Thompson","year":"2002","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0125","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/6572381","article-title":"A review of selected studies that determine the physical and chemical properties of saliva in the field of dental treatment","volume":"2018","author":"Kubala","year":"2018","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.jchromb.2023.123826_b0130","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1021\/es970526s","article-title":"Analysis of airborne carboxylic acids and phenols as their pentafluorobenzyl derivatives: Gas chromatography\/ion trap mass spectrometry with a novel chemical ionization reagent, PFBOH","volume":"32","author":"Chien","year":"1998","journal-title":"Environ. Sci. Tech."},{"key":"10.1016\/j.jchromb.2023.123826_b0135","doi-asserted-by":"crossref","DOI":"10.1366\/0003702914335193","article-title":"Selective determination of pentafluorobenzyl ester derivatives of carboxylic acids by GC using microwave plasma and mass selective detection","author":"Brill","year":"1991","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.jchromb.2023.123826_b0140","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.talanta.2014.07.022","article-title":"Stir bar sorptive extraction: Recent applications, limitations and future trends","volume":"130","author":"Camino-S\u00e1nchez","year":"2014","journal-title":"Talanta"},{"key":"10.1016\/j.jchromb.2023.123826_b0145","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ab.2017.03.007","article-title":"Analysis of short-chain fatty acids in human feces: A scoping review","volume":"526","author":"Primec","year":"2017","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.jchromb.2023.123826_b0150","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0021-9673(02)01870-8","article-title":"Determination of stale-flavor carbonyl compounds in beer by stir bar sorptive extraction with in-situ derivatization and thermal desorption-gas chromatography-mass spectrometry","volume":"986","author":"Ochiai","year":"2003","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2023.123826_b0155","doi-asserted-by":"crossref","DOI":"10.1088\/1752-7163\/aad202","article-title":"Determination of carbonyl compounds in exhaled breath by on-sorbent derivatization coupled with thermal desorption and gas chromatography-tandem mass spectrometry","volume":"12","author":"Lomonaco","year":"2018","journal-title":"J. Breath Res."},{"key":"10.1016\/j.jchromb.2023.123826_b0160","doi-asserted-by":"crossref","DOI":"10.3390\/ijms151119562","article-title":"Competing intramolecular vs. Intermolecular hydrogen bonds in solution","author":"Nagy","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jchromb.2023.123826_b0165","doi-asserted-by":"crossref","unstructured":"J.H. Na Hyun Park, Min-Sun Kim, Wonwoong Lee, Myoung Eun Lee, In situ extraction and derivatization method for rapid analysis of short-chain fatty acids in rat fecal sample by gas chromatography tandem mass spectrometry, (2017). https:\/\/doi.org\/10.1039\/C7AY00168A.","DOI":"10.1039\/C7AY00168A"},{"key":"10.1016\/j.jchromb.2023.123826_b0170","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1007\/s11306-013-0500-6","article-title":"A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids","volume":"9","author":"Zheng","year":"2013","journal-title":"Metabolomics"},{"key":"10.1016\/j.jchromb.2023.123826_b0175","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.foodchem.2011.04.022","article-title":"Development of a headspace solid-phase microextraction gas chromatography \u2013 mass spectrometric method for the determination of short-chain fatty acids from intestinal fermentation","volume":"129","author":"Bianchi","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.jchromb.2023.123826_b0180","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.cca.2022.05.005","article-title":"GC-MS analysis of short chain fatty acids and branched chain amino acids in urine and faeces samples from newborns and lactating mothers","volume":"532","author":"Ramos-Garcia","year":"2022","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jchromb.2023.123826_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2022.462958","article-title":"Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces","volume":"1669","author":"Zhu","year":"2022","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jchromb.2023.123826_b0190","doi-asserted-by":"crossref","DOI":"10.3390\/metabo12020170","article-title":"A gas chromatography mass spectrometry-based method for the quantification of short chain fatty acids","volume":"12","author":"Rohde","year":"2022","journal-title":"Metabolites"},{"key":"10.1016\/j.jchromb.2023.123826_b0195","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1029\/GL017i013p02361","article-title":"A photochemical origin of acetic acid in the troposphere","volume":"17","author":"Madronich","year":"1990","journal-title":"Geophys. Res. Lett."},{"key":"10.1016\/j.jchromb.2023.123826_b0200","first-page":"ZC34","article-title":"Salivary lactate dehydrogenase (LDH)- A novel technique in oral cancer detection and diagnosis","volume":"10","author":"Lokesh","year":"2016","journal-title":"J. Clin. Diag Res."},{"key":"10.1016\/j.jchromb.2023.123826_b0205","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.microc.2017.02.032","article-title":"The effect of sampling procedures on the urate and lactate concentration in oral fluid","volume":"136","author":"Lomonaco","year":"2018","journal-title":"Microchem. J."},{"key":"10.1016\/j.jchromb.2023.123826_b0210","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.pharmthera.2004.04.004","article-title":"Implications of the natriuretic peptide system in the pathogenesis of heart failure: Diagnostic and therapeutic importance","volume":"102","author":"Abassi","year":"2004","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2023.123826_b0215","doi-asserted-by":"crossref","DOI":"10.1186\/s13568-021-01200-0","article-title":"Effects of altitude on human oral microbes","volume":"11","author":"Liu","year":"2021","journal-title":"AMB Express"},{"key":"10.1016\/j.jchromb.2023.123826_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/life13010182","article-title":"The oral microbiota in valvular heart disease: current knowledge and future directions","volume":"13","author":"Neculae","year":"2023","journal-title":"Life."},{"key":"10.1016\/j.jchromb.2023.123826_b0225","first-page":"1","article-title":"The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights","volume":"13","author":"Li","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jchromb.2023.123826_b0230","doi-asserted-by":"crossref","first-page":"483","DOI":"10.4330\/wjc.v7.i8.483","article-title":"Clinical significance of lactate in acute cardiac patients","volume":"7","author":"Lazzeri","year":"2015","journal-title":"World J. Cardiol."},{"key":"10.1016\/j.jchromb.2023.123826_b0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-64112-2","article-title":"Salivary lactate and 8-isoprostaglandin F2\u03b1 as potential non-invasive biomarkers for monitoring heart failure: a pilot study","volume":"10","author":"Ghimenti","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jchromb.2023.123826_b0240","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1152\/japplphysiol.00255.2005","article-title":"Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion","volume":"100","author":"Okere","year":"2006","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.jchromb.2023.123826_b0245","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1161\/CIRCULATIONAHA.120.052671","article-title":"Short-chain fatty acids outpace ketone oxidation in the failing heart","volume":"143","author":"Carley","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jchromb.2023.123826_b0250","first-page":"1","article-title":"Cardiac complications of propionic and other inherited organic acidemias","volume":"7","author":"Park","year":"2020","journal-title":"Front. Cardi. Med."},{"key":"10.1016\/j.jchromb.2023.123826_b0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femspd\/ftaa024","article-title":"Oral bacteria affect the gut microbiome and intestinal immunity","volume":"78","author":"Kobayashi","year":"2020","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.jchromb.2023.123826_b0260","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1042\/CS20171090","article-title":"Gut microbiota in cardiovascular disease and heart failure","volume":"132","author":"Kitai","year":"2018","journal-title":"Clin. Sci."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223002362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223002362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:12:18Z","timestamp":1761606738000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023223002362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":52,"alternative-id":["S1570023223002362"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123826","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HiSorb sorptive extraction for determining salivary short chain fatty acids and hydroxy acids in heart failure patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123826","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"123826"}}