{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:18:13Z","timestamp":1761607093764,"version":"build-2065373602"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2020YFS0523"],"award-info":[{"award-number":["2020YFS0523"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jchromb.2023.123926","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T15:30:23Z","timestamp":1699457423000},"page":"123926","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Uncovering quality markers of Yiqi-Tongluo capsule against myocardial ischemia and optimization of its extraction process"],"prefix":"10.1016","volume":"1230","author":[{"given":"Meiyan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runchun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2023.123926_b0005","first-page":"620","article-title":"Research progress of symptom groups in patients with coronary heart disease","author":"Ma","year":"2022","journal-title":"Chin. Evid. Based Nurs."},{"key":"10.1016\/j.jchromb.2023.123926_b0010","series-title":"Study on preparation, quality control and anti-myocardial ischemia effect of Danhong core component dripping pill","first-page":"001973","author":"Wang","year":"2022"},{"key":"10.1016\/j.jchromb.2023.123926_b0015","article-title":"Clinical efficacy of Yiqi Tongluo Capsule combined with conventional western drugs in the treatment of myocardial ischemia","author":"Zhang","year":"2022","journal-title":"Sciencepaper Online."},{"key":"10.1016\/j.jchromb.2023.123926_b0020","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.794528","article-title":"An integrated approach based on network analysis combined with experimental verification reveals PI3K\/Akt\/Nrf2 signaling is an important way for the anti-myocardial ischemia activity of Yi-Qi-Tong-Luo Capsule","volume":"13","author":"Duan","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0025","first-page":"2128","article-title":"Effects of Yiqi Tongluo Granules on primary cortical neurons cell viability, toxicity and mitochondrial membrane potential","volume":"60","author":"Xue","year":"2019","journal-title":"J. Trad. Chin. Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0030","first-page":"117","article-title":"Therapy for cardiovascular disease by Astagaloside IV","volume":"30","author":"Liu","year":"2013","journal-title":"Infor Trad Chin Med."},{"issue":"24","key":"10.1016\/j.jchromb.2023.123926_b0035","first-page":"4612","article-title":"Astragaloside IV attenuates myocardial apoptosis induced by ischemia-reperfusion in rats","volume":"20","author":"Zeng","year":"2020","journal-title":"Progress in Modern Biomedicine"},{"key":"10.1016\/j.jchromb.2023.123926_b0040","first-page":"43","article-title":"Protective effect of calycosin in Astragalus membranaceus at different doses on nerve cells after cerebral ischemia-reperfusion in rats","volume":"37","author":"Zhang","year":"2022","journal-title":"J Hebei TCM Pharm."},{"key":"10.1016\/j.jchromb.2023.123926_b0045","first-page":"341","article-title":"Protective effect of calycosin on myocardial ischemia-reperfusion injury in rats","volume":"34","author":"Li","year":"2017","journal-title":"Tianjin J Trad Chin Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0050","first-page":"128","article-title":"Research progress on chemical constituents and pharmacological effects of Ligusticum chuanxiong Hort","volume":"37","author":"Zhang","year":"2020","journal-title":"Infor Trad Chin Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0055","first-page":"772","article-title":"Pharmacological research progress of sodium ferulate in cardio-cerebral vascular disease","volume":"50","author":"Wang","year":"2019","journal-title":"Chin Trad Herbal Drugs."},{"key":"10.1016\/j.jchromb.2023.123926_b0060","first-page":"1","article-title":"Chuanxiong-pathalide A-induced preconditioning in isolated Langendorff rat hearts","volume":"06","author":"Liang","year":"2004","journal-title":"Pharmacol Clin Chine Mater Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0065","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.neulet.2012.04.003","article-title":"DL-3-N-butylphthalide protects rat bone marrow stem cells against hydrogen peroxide-induced cell death through antioxidation and activation of PI3K-Akt pathway","volume":"516","author":"Sun","year":"2012","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jchromb.2023.123926_b0070","first-page":"1776","article-title":"Protective effect of ligustilide on myocardial injury induced by doxorubicin","volume":"32","author":"Sun","year":"2021","journal-title":"Trad Chin Drug Res Clin Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0075","article-title":"Levistilide A promotes expansion of human umbilical cord blood hematopoietic stem cells by enhancing antioxidant activity","volume":"13","author":"He","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.coph.2021.11.009","article-title":"Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis","volume":"62","author":"Peng","year":"2022","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0085","first-page":"47","article-title":"Research progress of paeoniflorin","volume":"40","author":"Che","year":"2021","journal-title":"J Trad Chin Veter Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0090","first-page":"926","article-title":"Protection against myocardial ischemia \/reperfusion injury in rats by pretreatment with paeoniflorin","volume":"18","author":"Liu","year":"2015","journal-title":"Chin Pharm."},{"key":"10.1016\/j.jchromb.2023.123926_b0095","first-page":"5229","article-title":"Research ideas and progress on screening and identification of pharmacodynamic substance of Chinese materia medica","volume":"22","author":"Bi","year":"2018","journal-title":"Chin Trad Herbal Drugs."},{"key":"10.1016\/j.jchromb.2023.123926_b0100","doi-asserted-by":"crossref","first-page":"1166178","DOI":"10.3389\/fphar.2023.1166178","article-title":"Radical oxygen species: an important breakthrough point for botanical drugs to regulate oxidative stress and treat the disorder of glycolipid metabolism","volume":"14","author":"Luo","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0105","first-page":"1443","article-title":"A new concept on quality marker of Chinese materia medica: Quality control for Chinese medicinal products","volume":"47","author":"Liu","year":"2016","journal-title":"Chin Trad Herbal Drugs."},{"key":"10.1016\/j.jchromb.2023.123926_b0110","first-page":"1","article-title":"Research progress in chemical constituents and pharmacological effects of pogostemon cablin and predictive analysis of Q-Marker","author":"Li","year":"2023","journal-title":"Chin. Pharm. J."},{"key":"10.1016\/j.jchromb.2023.123926_b0115","first-page":"1","article-title":"Predictive analysis of Quality Marker (Q-Marker) of classic whitening compound Sanbai Decoction, Mod","author":"Xiao","year":"2023","journal-title":"Chin. Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0120","first-page":"1","article-title":"Research progress of Shegan Mahuang decoction and predictive analysis on Q-markers","author":"Li","year":"2023","journal-title":"Chin J Chin Mater Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0125","article-title":"Research progress and development trend of serum medicinal chemistry of traditional Chinese medicine","author":"Wang","year":"2006","journal-title":"Chin J Chin Mater Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0130","first-page":"142","article-title":"Chemical profiling of Dagaoliangjiang (Alpinia galangal L.) alcohol extract and blood components of rat s with gastric ulcer with cold Syndrome after oral administration based on HOLC-Q-TOF\/MS","volume":"40","author":"Yin","year":"2022","journal-title":"Chin Arch Trad Chin Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0135","first-page":"418","article-title":"Effects of gut microbiota on five absorbed components of Berberis kansuensis in rat serum by HPLC-QqQ-MS","volume":"45","author":"Du","year":"2020","journal-title":"Chin J Chin Mater Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0140","first-page":"352","article-title":"Analysis on migrating constituents absorbed into blood of mice after ig administration of Resina Draconis","volume":"40","author":"Chen","year":"2009","journal-title":"Chin Trad Herbal Drugs."},{"key":"10.1016\/j.jchromb.2023.123926_b0145","first-page":"530","article-title":"Role of Mongolian Amomum Tsaoko four flavor soup against H9c2 myocardial cells damage induced by isoprenaline","volume":"32","author":"Shu","year":"2017","journal-title":"J Inner Mongolia Univ National."},{"key":"10.1016\/j.jchromb.2023.123926_b0150","first-page":"2015","article-title":"Protective effect of notopterol on isoproterenol induced H9c2 cell injury","volume":"37","author":"Wang","year":"2021","journal-title":"Chin J Clin Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123926_b0155","first-page":"730","article-title":"Mechanism of Astragaloside IV alleviating hypertrophic Injury of H9c2 cells induced by isoproterenol","author":"Lu","year":"2023","journal-title":"J Chin Med Mater."},{"key":"10.1016\/j.jchromb.2023.123926_b0160","doi-asserted-by":"crossref","first-page":"9265016","DOI":"10.1155\/2021\/9265016","article-title":"SFRP2 improves mitochondrial dynamics and mitochondrial biogenesis, oxidative stress, and apoptosis in diabetic cardiomyopathy","volume":"2021","author":"Ma","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.jchromb.2023.123926_b0165","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.3390\/molecules26185485","article-title":"Optimization of taxol extraction process using response surface methodology and investigation of temporal and spatial distribution of taxol in taxus mairei","volume":"26","author":"Li","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.jchromb.2023.123926_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153525","article-title":"A multi-strategy platform for quality control and Q-markers screen of Chaiqin chengqi decoction","volume":"85","author":"Liang","year":"2021","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jchromb.2023.123926_b0175","doi-asserted-by":"crossref","first-page":"e23015","DOI":"10.53388\/TMRIM202307015","article-title":"Traditional Chinese medicine: Eastern natural remedy for management of lipid metabolic disorders","volume":"7","author":"Peng","year":"2023","journal-title":"TMR Integr Med."},{"key":"10.1016\/j.jchromb.2023.123926_b0180","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.apsb.2017.04.012","article-title":"Approaches to establish Q-markers for the quality standards of traditional Chinese medicines","volume":"7","author":"Yang","year":"2017","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.jchromb.2023.123926_b0185","first-page":"39","article-title":"Main research methods of pharmacodynamic substance basis of traditional Chinese medicine","volume":"12","author":"Zhao","year":"2022","journal-title":"Chin Med Pharm."},{"issue":"12","key":"10.1016\/j.jchromb.2023.123926_b0190","doi-asserted-by":"crossref","first-page":"20808","DOI":"10.3390\/molecules191220808","article-title":"Optimization of ultrasonic-assisted extraction of cordycepin from Cordyceps militaris using orthogonal experimental design","volume":"19","author":"Wang","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.jchromb.2023.123926_b0195","first-page":"481","article-title":"Present situation and thinking of Chinese traditional compound medicine research","volume":"06","author":"He","year":"2001","journal-title":"Progr Chem Ry."},{"year":"2015","author":"Ao","series-title":"Pharmacology studies on Zao Ling An Shen compound","key":"10.1016\/j.jchromb.2023.123926_b0200"},{"issue":"05","key":"10.1016\/j.jchromb.2023.123926_b0205","first-page":"611","article-title":"Application of fingerprint technology on traditional Chinese medicine in Chinese pharmacopoeia (2015 Edition) volume I","volume":"33","author":"Zhu","year":"2016","journal-title":"Chin J Mod Appl Pharm."},{"key":"10.1016\/j.jchromb.2023.123926_b0210","first-page":"23","article-title":"Application of TCM fingerprint similarity software in the teaching of \u201cPharmaceutical Analysis\u201d","volume":"01","author":"Zhou","year":"2020","journal-title":"Teach Fore Region"},{"key":"10.1016\/j.jchromb.2023.123926_b0215","first-page":"33","article-title":"Fingerprint technology of traditional Chinese medicine","author":"Shi","year":"2004","journal-title":"Univ. Chem."},{"key":"10.1016\/j.jchromb.2023.123926_b0220","first-page":"1","article-title":"Evaluation on the correlation of material of Yangxue Liniao Granules based on high performance liquid chromatography fingerprint","author":"Xie","year":"2023","journal-title":"Chin J Hosp Pharm."},{"key":"10.1016\/j.jchromb.2023.123926_b0225","first-page":"298","article-title":"Establishment of fingerprint and determination of differential components of Sophora flavescens","volume":"34","author":"Dong","year":"2023","journal-title":"Chin Pharm."},{"key":"10.1016\/j.jchromb.2023.123926_b0230","first-page":"51","article-title":"Study on fingerprint of Chinese herbal compound Yiguanjian by high performance liquid chromatography","volume":"20","author":"Zhao","year":"2018","journal-title":"J Liaoning Univ TCM."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223003367?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223003367?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:11:39Z","timestamp":1761606699000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023223003367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":46,"alternative-id":["S1570023223003367"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123926","relation":{},"ISSN":["1570-0232"],"issn-type":[{"type":"print","value":"1570-0232"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uncovering quality markers of Yiqi-Tongluo capsule against myocardial ischemia and optimization of its extraction process","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123926","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"123926"}}