{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T19:05:58Z","timestamp":1776452758334,"version":"3.51.2"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,25]],"date-time":"2023-12-25T00:00:00Z","timestamp":1703462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.jchromb.2023.123988","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T21:54:01Z","timestamp":1703800441000},"page":"123988","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Extraction and analysis of moxidectin in wombat plasma and faeces"],"prefix":"10.1016","volume":"1233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6328-9388","authenticated-orcid":false,"given":"Gregory S.","family":"Doran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Wynan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ray","family":"Wynan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Ralph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley J.","family":"Stannard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchromb.2023.123988_b0005","unstructured":"S.D.Z.W. Alliance, Wombats (Vombatus and Lasiorhinus spp.) fact sheet, http:\/\/ielc.libguides.com\/sdzg\/factsheets\/wombats, San Diego Zoo, California, USA, 2015."},{"key":"10.1016\/j.jchromb.2023.123988_b0010","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s13071-017-2234-1","article-title":"A review of Sarcoptes scabiei: past, present and future","volume":"10","author":"Arlian","year":"2017","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.jchromb.2023.123988_b0015","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.944578","article-title":"Pathophysiological and pharmaceutical considerations for enhancing the control of Sarcoptes scabiei in wombats through improved transdermal drug delivery","volume":"9","author":"Bains","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.jchromb.2023.123988_b0020","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7589\/0090-3558-39.1.179","article-title":"Clinical response of captive common wombats (Vombatus ursinus) infected with Sarcoptes scabiei var. wombati","volume":"39","author":"Skerratt","year":"2003","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.jchromb.2023.123988_b0025","doi-asserted-by":"crossref","first-page":"643","DOI":"10.7589\/0090-3558-47.3.643","article-title":"Pharmacokinetics of moxidectin in the southern hairy-nosed wombat (Lasiorhinus latifrons)","volume":"47","author":"Death","year":"2011","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.jchromb.2023.123988_b0030","doi-asserted-by":"crossref","first-page":"312","DOI":"10.7589\/2012-10-256","article-title":"Effects and treatment of sarcoptic mange in southern hairy-nosed wombats (Lasiorhinus latifrons)","volume":"49","author":"Ruykys","year":"2013","journal-title":"J. Wildl. Dis."},{"key":"10.1016\/j.jchromb.2023.123988_b0035","unstructured":"APVMA, Permit to allow supply and minor use of a registered agvet chemical - Product for control of sarcoptic mange in wombats, in: A.P.a.V.M. Authority (Ed.), Armidale, NSW, Australia, 2023, pp. 1\u20135."},{"key":"10.1016\/j.jchromb.2023.123988_b0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005030","article-title":"Preclinical study of single-dose moxidectin, a new oral treatment for scabies: efficacy, safety, and pharmacokinetics compared to two-dose ivermectin in a porcine model","volume":"10","author":"Bernigaud","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jchromb.2023.123988_b0045","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1093\/oxfordjournals.epirev.a036033","article-title":"Epidemiology of scabies","volume":"11","author":"Green","year":"1989","journal-title":"Epidemiol. Rev."},{"key":"10.1016\/j.jchromb.2023.123988_b0050","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1053\/tvjl.2000.0521","article-title":"Faecal excretion profile of moxidectin and ivermectin after oral administration in horses","volume":"161","author":"Perez","year":"2001","journal-title":"Vet. J."},{"key":"10.1016\/j.jchromb.2023.123988_b0055","first-page":"437","article-title":"Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans","volume":"138","author":"Bassissi","year":"2004","journal-title":"Comp. Biochem. Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.jchromb.2023.123988_b0060","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1258\/la.2009.009053","article-title":"Plasma dispositions of ivermectin, doramectin and moxidectin following subcutaneous administration in rabbits","volume":"44","author":"Gokbulut","year":"2010","journal-title":"Lab. Anim"},{"key":"10.1016\/j.jchromb.2023.123988_b0065","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0731-7085(02)00120-6","article-title":"Liquid chromatographic assay of moxidectin in human plasma for application to pharmacokinetic studies","volume":"29","author":"Chen","year":"2002","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jchromb.2023.123988_b0070","doi-asserted-by":"crossref","DOI":"10.1002\/bmc.4389","article-title":"Bioanalytical method development and validation of moxidectin in plasma by LC\u2013MS\/MS: application to in vitro metabolism","volume":"33","author":"Chhonker","year":"2019","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jchromb.2023.123988_b0075","first-page":"250","article-title":"Determination of moxidectin in serum by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study in lambs","volume":"28","author":"Baptista","year":"2017","journal-title":"J. Braz. Chem. Soc."},{"key":"10.1016\/j.jchromb.2023.123988_b0080","first-page":"545","article-title":"Plasma profile study of moxidectin in a cow and its suckling calf","volume":"27","author":"Alvinerie","year":"1996","journal-title":"Vet. Res."},{"key":"10.1016\/j.jchromb.2023.123988_b0085","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1638\/2016-0077R.1","article-title":"Pilot study: Pharmacokinetics of oral and topical moxidectin in the reticulated giraffe (Giraffa camelopardalis)","volume":"48","author":"West","year":"2017","journal-title":"J. Zoo Wildl. Med."},{"key":"10.1016\/j.jchromb.2023.123988_b0090","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27030998","article-title":"Development and validation of a reliable UHPLC-MS\/MS method for simultaneous quantification of macrocyclic lactones in bovine plasma","volume":"27","author":"Zeleke","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.jchromb.2023.123988_b0095","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1177\/104063870201400404","article-title":"Isolation and multiresidue detection of macrolide endectocides present in animal matrices","volume":"14","author":"Rudik","year":"2002","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1016\/j.jchromb.2023.123988_b0100","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jchromb.2006.11.014","article-title":"Positive and negative electrospray LC-MS-MS methods for quantitation of the antiparasitic endectocide drugs, abamectin, doramectin, emamectin, eprinomectin, ivermectin, moxidectin and selamectin in milk","volume":"850","author":"Durden","year":"2007","journal-title":"J. Chromatogr. B Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.jchromb.2023.123988_b0105","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.4155\/bio-2018-0110","article-title":"A sensitive and selective LC\u2013MS\/MS method for quantitation of ivermectin in human, mouse and monkey plasma: clinical validation","volume":"10","author":"Chhonker","year":"2018","journal-title":"Bioanalysis"},{"key":"10.1016\/j.jchromb.2023.123988_b0110","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1039\/c1ay05236e","article-title":"Gas chromatography-mass spectrometric determination of ivermectin following trimethylsilylation with application to residue analysis in biological meat tissue samples","volume":"3","author":"Sanbonsuge","year":"2011","journal-title":"Anal. Methods"},{"key":"10.1016\/j.jchromb.2023.123988_b0115","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-4347(95)00294-5","article-title":"Determination of moxidectin in plasma by high-performance liquid chromatography with automated solid-phase extraction and fluorescence detection","volume":"674","author":"Alvinerie","year":"1995","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.jchromb.2023.123988_b0120","first-page":"180","article-title":"Rapid analysis of moxidectin in plasma","volume":"73","author":"Hughes","year":"2013","journal-title":"Proc. N. Z. Soc. Anim. Prod."},{"key":"10.1016\/j.jchromb.2023.123988_b0125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.1365-2885.1997.00825.x","article-title":"Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle","volume":"20","author":"Lanusse","year":"1997","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2023.123988_b0130","series-title":"Lipoproteins as Carriers of Pharmacological Agents","first-page":"156","article-title":"G. W., Lipoproteins and microemulsions as as carriers of therpeutic and chemical agents","author":"Florence","year":"1991"},{"key":"10.1016\/j.jchromb.2023.123988_b0135","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1365-2885.2005.00674.x","article-title":"Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents","volume":"28","author":"Lifschitz","year":"2005","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2023.123988_b0140","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ijpddr.2012.04.001","article-title":"Moxidectin and the avermectins: consanguinity but not identity","volume":"2","author":"Prichard","year":"2012","journal-title":"Int. J. Parasitol. Drugs Drug Resist."},{"key":"10.1016\/j.jchromb.2023.123988_b0145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.smallrumres.2019.02.015","article-title":"Faecal excretion of moxidectin in lambs and its persistence in different environmental conditions","volume":"174","author":"Hentz","year":"2019","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.jchromb.2023.123988_b0150","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.vetpar.2007.05.002","article-title":"Pharmacokinetics assessment of moxidectin long-acting formulation in cattle","volume":"147","author":"Dupuy","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jchromb.2023.123988_b0155","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1046\/j.1365-2885.2002.00435.x","article-title":"Does the rate of fat deposition influence the pharmacokinetic disposition of subcutaneously administered moxidectin and ivermectin in pigs?","volume":"25","author":"Craven","year":"2002","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.jchromb.2023.123988_b0160","unstructured":"I.a.E. State of NSW and Department of Planning, Guidelines for the treatment and care of rescued wombats, 2021, pp. 40."},{"key":"10.1016\/j.jchromb.2023.123988_b0165","unstructured":"F.D.A. Health, Environmental Assessment - Cydectin moxidectin 0.5% Pour-On for Cattle, New Jersey, US, 1997."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223003987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570023223003987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T23:12:29Z","timestamp":1761606749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570023223003987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":33,"alternative-id":["S1570023223003987"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123988","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extraction and analysis of moxidectin in wombat plasma and faeces","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2023.123988","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"123988"}}