{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T20:52:44Z","timestamp":1780519964980,"version":"3.54.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chromatography B"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jchromb.2025.124538","type":"journal-article","created":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T10:15:32Z","timestamp":1740305732000},"page":"124538","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Serum untargeted metabolomics combined with mouse models reveals potential mechanisms of ChengShu QingChu decoction for the treatment of vitiligo"],"prefix":"10.1016","volume":"1256","author":[{"given":"Xiangran","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abudureyimu","family":"Alimujiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengqiu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuerxun","family":"Wufuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julaiti","family":"Abuduwayiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shixia","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jchromb.2025.124538_bb0005","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s12016-021-08868-z","article-title":"Clinical features, Immunopathogenesis, and therapeutic strategies in vitiligo","volume":"61","author":"Wang","year":"2021","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0010","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1146\/annurev-immunol-100919-023531","article-title":"Vitiligo: mechanisms of pathogenesis and treatment","volume":"38","author":"Frisoli","year":"2020","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s12016-017-8622-7","article-title":"Vitiligo: focus on clinical aspects, Immunopathogenesis, and therapy","volume":"54","author":"Boniface","year":"2018","journal-title":"Clin. Rev. Allergy Immunol."},{"issue":"7844","key":"10.1016\/j.jchromb.2025.124538_bb0020","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/s41586-020-03053-2","article-title":"A genetic history of the pre-contact Caribbean","volume":"590","author":"Fernandes","year":"2021","journal-title":"Nature"},{"issue":"9988","key":"10.1016\/j.jchromb.2025.124538_bb0025","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0140-6736(14)60763-7","article-title":"Vitiligo","volume":"386","author":"Ezzedine","year":"2015","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.jchromb.2025.124538_bb0030","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.det.2016.11.007","article-title":"Medical and maintenance treatments for vitiligo","volume":"35","author":"Passeron","year":"2017","journal-title":"Dermatol. Clin."},{"issue":"4","key":"10.1016\/j.jchromb.2025.124538_bb0035","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2310\/7750.2013.12053","article-title":"Low-dose oral mini-pulse dexamethasone therapy in progressive unstable vitiligo","volume":"17","author":"Kanwar","year":"2013","journal-title":"J. Cutan. Med. Surg."},{"key":"10.1016\/j.jchromb.2025.124538_bb0040","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1365-2133.1976.tb02268.x","article-title":"The treatment of vitiligo with topical corticosteroids. Light and electronmicroscopic studies","volume":"12","author":"Bleehen","year":"1976","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.jchromb.2025.124538_bb0045","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.det.2016.11.008","article-title":"Phototherapy and combination therapies for vitiligo","volume":"35","author":"Esmat","year":"2017","journal-title":"Dermatol. Clin."},{"issue":"4","key":"10.1016\/j.jchromb.2025.124538_bb0050","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1038\/jid.2014.527","article-title":"Maintenance therapy of adult vitiligo with 0.1% tacrolimus ointment: a randomized, double blind, placebo-controlled study","volume":"135","author":"Cavali\u00e9","year":"2015","journal-title":"J. Invest. Dermatol."},{"issue":"10","key":"10.1016\/j.jchromb.2025.124538_bb0055","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3390\/biom9100512","article-title":"HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-\u03baB signaling pathways","volume":"9","author":"Xie","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.jchromb.2025.124538_bb0060","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1472-6882-11-21","article-title":"Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial","volume":"11","author":"Szczurko","year":"2011","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.jchromb.2025.124538_bb0065","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ctim.2016.02.009","article-title":"Oral Chinese herbal medicine in combination with phototherapy for vitiligo: a systematic review and meta-analysis of randomized controlled trials","volume":"26","author":"Chen","year":"2016","journal-title":"Complement. Ther. Med."},{"issue":"2","key":"10.1016\/j.jchromb.2025.124538_bb0070","doi-asserted-by":"crossref","first-page":"301","DOI":"10.4314\/ajtcam.v11i2.13","article-title":"An assessment of traditional Uighur medicine in current Xinjiang region (China)","volume":"11","author":"Ma","year":"2014","journal-title":"African J. Traditi. Complement. Altern. Med."},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0075","first-page":"1056","article-title":"Syndrome differentiation of 1051 patients with vitiligo in Uygur medicine","volume":"24","author":"Wufuer","year":"2010","journal-title":"Chin. J. Dermatovenerology"},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0080","first-page":"203","article-title":"Vitiligo syndrome classification and Uygur medicine medical law analysis","volume":"21","author":"Erken","year":"2015","journal-title":"Chin. J. Exp. Tradit. Med. Formulae"},{"key":"10.1016\/j.jchromb.2025.124538_bb0085","first-page":"61","article-title":"Vitiligo Uygur medicine guidelines","volume":"8","author":"Wufuer","year":"2008","journal-title":"J. Med. Pharm. Chin. Minorities"},{"issue":"03","key":"10.1016\/j.jchromb.2025.124538_bb0090","first-page":"161","article-title":"Therapeutic efficacy of Uygur medical ChengShu and QingChu decoction in the treatment of 166 cases of progressive vitiligo.Pharmacology and clinics of Chinese materia","volume":"28","author":"Wufuer","year":"2012","journal-title":"Medica"},{"issue":"01","key":"10.1016\/j.jchromb.2025.124538_bb0095","first-page":"80","article-title":"Therapeutic effect observation of 273 cases of vitiligo treated with ChengShu and QingChu decoction of Uygur medicine.The","volume":"26","author":"Wufuer","year":"2012","journal-title":"Chin. J. Dermatovenereology"},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0100","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1080\/004982599238047","article-title":"\u2018Metabonomics\u2019: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data","volume":"29","author":"Nicholson","year":"1999","journal-title":"Xenobiotica; Fate Foreign Compd. Biol. Syst."},{"key":"10.1016\/j.jchromb.2025.124538_bb0105","article-title":"Uncovering the mechanisms of Zhubi decoction against rheumatoid arthritis through an integrated study of network pharmacology, metabolomics, and intestinal flora","volume":"336","author":"Jing","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0110","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/ng1109","article-title":"Bioinformatics in the post-sequence era","volume":"33","author":"Kanehisa","year":"2003","journal-title":"Nat. Genet."},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25115880","article-title":"Bioinformatics analysis and validation of potential markers associated with prediction and prognosis of gastric cancer","volume":"25","author":"Matsuoka","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.jchromb.2025.124538_bb0120","first-page":"105","article-title":"Committee of the Chinese society of integrative medicine (CSIM).Consensus on the diagnosis and treatment of vitiligo X","volume":"54","author":"Pigmentation Disease Group of the Skin and Venereal Disease","year":"2021","journal-title":"Chin. J. Dermatol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0125","doi-asserted-by":"crossref","first-page":"D521","DOI":"10.1093\/nar\/gkl923","article-title":"HMDB: the human metabolome database","volume":"3","author":"Wishart","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jchromb.2025.124538_bb0130","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/978-1-0716-0239-3_9","article-title":"METLIN: a tandem mass spectral library of standards","volume":"2104","author":"Burke","year":"2020","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0135","doi-asserted-by":"crossref","first-page":"D527","DOI":"10.1093\/nar\/gkl838","article-title":"LMSD: LIPID MAPS structure database","volume":"35","author":"Sud","year":"2007","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.jchromb.2025.124538_bb0140","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1021\/acs.jproteome.5b00354","article-title":"Analysis of the human adult urinary metabolome variations with age,body mass index,and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses","volume":"14","author":"Th\u00e9venot","year":"2015","journal-title":"J. Proteome Res."},{"issue":"6","key":"10.1016\/j.jchromb.2025.124538_bb0145","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/nprot.2011.319","article-title":"Web-based inference of biological patterns,functions and pathways from metabolomic data using METABOANALYST","volume":"6","author":"Xia","year":"2011","journal-title":"Nat. Protoc."},{"issue":"1","key":"10.1016\/j.jchromb.2025.124538_bb0150","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Ogata","year":"2000","journal-title":"Nucleic Acids Res."},{"issue":"14","key":"10.1016\/j.jchromb.2025.124538_bb0155","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1093\/bioinformatics\/btm254","article-title":"GEOquery: a bridge between the gene expression omnibus (GEO) and BioConductor","volume":"23","author":"Davis","year":"2007","journal-title":"Bioinformatics"},{"issue":"7","key":"10.1016\/j.jchromb.2025.124538_bb0160","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.jchromb.2025.124538_bb0165","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1093\/ecco-jcc\/jjad049","article-title":"Serum immune profiling in Paediatric Crohn\u2019s disease demonstrates stronger immune modulation with first-line infliximab than conventional therapy and pre-treatment profiles predict clinical response to both treatments","volume":"17","author":"Jongsma","year":"2023","journal-title":"J. Crohns Colitis"},{"issue":"7","key":"10.1016\/j.jchromb.2025.124538_bb0170","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.3390\/nu15071694","article-title":"Integration of metabolomics and transcriptomics to reveal the metabolic characteristics of exercise-improved bone mass","volume":"15","author":"Hou","year":"2023","journal-title":"Nutrients"},{"issue":"D1","key":"10.1016\/j.jchromb.2025.124538_bb0175","doi-asserted-by":"crossref","first-page":"D638","DOI":"10.1093\/nar\/gkac1000","article-title":"The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest","volume":"51","author":"Szklarczyk","year":"2023","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.jchromb.2025.124538_bb0180","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat. Commun."},{"issue":"13","key":"10.1016\/j.jchromb.2025.124538_bb0185","article-title":"A novel immune-related gene signature to identify the tumor microenvironment and Prognose disease among patients with Oral squamous cell carcinoma patients using ssGSEA: a bioinformatics and biological validation study","volume":"6","author":"Chen","year":"2022","journal-title":"Front. Immunol."},{"issue":"7","key":"10.1016\/j.jchromb.2025.124538_bb0190","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/exd.12184","article-title":"A mouse model of vitiligo induced by monobenzone","volume":"22","author":"Zhu","year":"2013","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.jchromb.2025.124538_bb0195","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.711080","article-title":"Editorial: immunology of vitiligo","volume":"12","author":"Seneschal","year":"2021","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.jchromb.2025.124538_bb0200","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.cell.2017.04.004","article-title":"Metabolic instruction of immunity","volume":"169","author":"Buck","year":"2017","journal-title":"Cell"},{"issue":"9","key":"10.1016\/j.jchromb.2025.124538_bb0205","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/nri.2016.70","article-title":"A guide to immunometabolism for immunologists","volume":"16","author":"O\u2019Neill","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"7644","key":"10.1016\/j.jchromb.2025.124538_bb0210","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/nature21379","article-title":"Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism","volume":"543","author":"Pan","year":"2017","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jchromb.2025.124538_bb0215","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1161\/01.RES.87.1.52","article-title":"Lysophosphatidylcholine activates p38 and p42\/44 mitogen-activated protein kinases in monocytic THP-1 cells,but only p38 activation is involved in its stimulated chemotaxis","volume":"87","author":"Jing","year":"2000","journal-title":"Circ. Res."},{"issue":"8","key":"10.1016\/j.jchromb.2025.124538_bb0220","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1073\/pnas.85.8.2805","article-title":"Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis","volume":"85","author":"Quinn","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.jchromb.2025.124538_bb0225","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1073\/pnas.2536801100","article-title":"T cell chemotaxis to lysophosphatidylcholine through the G2A receptor","volume":"101","author":"Radu","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"9","key":"10.1016\/j.jchromb.2025.124538_bb0230","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1002\/eji.200526129","article-title":"Human resting CD16-,CD16+ and IL-2-,IL-12-,IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine,lysophosphatidylcholine and platelet-activating factor","volume":"35","author":"Jin","year":"2005","journal-title":"Eur. J. Immunol."},{"issue":"4","key":"10.1016\/j.jchromb.2025.124538_bb0235","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.jid.2021.09.015","article-title":"Vitiligo skin T cells are prone to produce type 1 and type 2 cytokines to induce melanocyte dysfunction and epidermal inflammatory response through Jak signaling","volume":"142","author":"Martins","year":"2022","journal-title":"J. Invest. Dermatol."},{"issue":"10","key":"10.1016\/j.jchromb.2025.124538_bb0240","doi-asserted-by":"crossref","first-page":"4651","DOI":"10.1111\/jocd.14922","article-title":"Differentiating active from stable vitiligo: the role of dermoscopic findings and their relation to CXCL10","volume":"21","author":"Ibrahim","year":"2022","journal-title":"J. Cosmet. Dermatol."},{"issue":"8","key":"10.1016\/j.jchromb.2025.124538_bb0245","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1111\/jocd.13908","article-title":"Elevated serum level of interleukin-15 in vitiligo patients and its correlation with disease severity but not activity","volume":"20","author":"Atwa","year":"2021","journal-title":"J. Cosmet. Dermatol."},{"issue":"31","key":"10.1016\/j.jchromb.2025.124538_bb0250","doi-asserted-by":"crossref","first-page":"49259","DOI":"10.18632\/oncotarget.10272","article-title":"Concerted action of IFN-\u03b1 and IFN-\u03bb induces local NK cell immunity and halts cancer growth","volume":"7","author":"Lasfar","year":"2016","journal-title":"Oncotarget"},{"issue":"10","key":"10.1016\/j.jchromb.2025.124538_bb0255","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.it.2022.08.004","article-title":"Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy","volume":"43","author":"Ma","year":"2022","journal-title":"Trends Immunol."},{"issue":"7891","key":"10.1016\/j.jchromb.2025.124538_bb0260","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/s41586-021-04221-8","article-title":"Anatomically distinct fibroblast subsets determine skin autoimmune patterns","volume":"601","author":"Xu","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.jchromb.2025.124538_bb0265","article-title":"The arachidonic acid metabolism mechanism based on UPLC-MS\/MS metabolomics in recurrent spontaneous abortion rats","volume":"12","author":"Li","year":"2021","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0270","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1158\/1541-7786.MCR-10-0002","article-title":"Multiple roles of protein kinase a in arachidonic acid-mediated Ca2+ entry and tumor-derived human endothelial cell migration","volume":"8","author":"Pla","year":"2010","journal-title":"Mol. Cancer Res."},{"issue":"5","key":"10.1016\/j.jchromb.2025.124538_bb0275","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4161\/chan.4.5.13226","article-title":"The N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid","volume":"4","author":"Thompson","year":"2010","journal-title":"Channels (Austin,Tex)"},{"issue":"9","key":"10.1016\/j.jchromb.2025.124538_bb0280","doi-asserted-by":"crossref","first-page":"6494","DOI":"10.1074\/jbc.M608966200","article-title":"Novel mechanism of activation of NADPH oxidase 5. Calcium sensitization via phosphorylation","volume":"282","author":"Jagnandan","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.jchromb.2025.124538_bb0285","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.2337\/diabetes.49.11.1939","article-title":"High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells","volume":"49","author":"Inoguchi","year":"2000","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.jchromb.2025.124538_bb0290","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jaci.2016.10.013","article-title":"Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes","volume":"140","author":"Li","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.jchromb.2025.124538_bb0295","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/1523-1747.ep12477126","article-title":"Human melanocytes as a target tissue for hormones: in vitro studies with 1 alpha-25, dihydroxyvitamin D3,alpha-melanocyte stimulating hormone,and beta-estradiol","volume":"91","author":"Ranson","year":"1988","journal-title":"J. Invest. Dermatol."},{"issue":"10244","key":"10.1016\/j.jchromb.2025.124538_bb0300","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0140-6736(20)30609-7","article-title":"Ruxolitinib cream for treatment of vitiligo: a randomised,controlled,phase 2 trial","volume":"396","author":"Rosmarin","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.jchromb.2025.124538_bb0305","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.790125","article-title":"Janus kinase inhibitors in the treatment of vitiligo: a review","volume":"12","author":"Qi","year":"2021","journal-title":"Front. Immunol."}],"container-title":["Journal of Chromatography B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157002322500090X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157002322500090X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T22:11:58Z","timestamp":1762553518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S157002322500090X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":61,"alternative-id":["S157002322500090X"],"URL":"https:\/\/doi.org\/10.1016\/j.jchromb.2025.124538","relation":{},"ISSN":["1570-0232"],"issn-type":[{"value":"1570-0232","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum untargeted metabolomics combined with mouse models reveals potential mechanisms of ChengShu QingChu decoction for the treatment of vitiligo","name":"articletitle","label":"Article Title"},{"value":"Journal of Chromatography B","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchromb.2025.124538","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"124538"}}