{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:33:52Z","timestamp":1786991632979,"version":"build-2736575974"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":599,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.jcin.2011.09.013","type":"journal-article","created":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T11:23:15Z","timestamp":1326108195000},"page":"105-111","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Percutaneous Edge-to-Edge Mitral Valve Repair in High-Surgical-Risk Patients"],"prefix":"10.1016","volume":"5","author":[{"given":"Ben J.L.","family":"Van den Branden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Swaans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn C.","family":"Post","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benno J.W.M.","family":"Rensing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank D.","family":"Eefting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wybren","family":"Jaarsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan A.S.","family":"Van der Heyden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2011.09.013_bib1","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0140-6736(09)60692-9","article-title":"Mitral regurgitation","volume":"373","author":"Enriquez-Sarano","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jcin.2011.09.013_bib2","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/eurjhf\/hfp051","article-title":"Long-term prognosis of medically treated patients with functional mitral regurgitation and left ventricular dysfunction","volume":"11","author":"Agricola","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2011.09.013_bib3","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jacc.2008.02.084","article-title":"The current therapy for mitral regurgitation","volume":"52","author":"Carabello","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib4","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2006.05.021","volume":"48","author":"Bonow","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib5","first-page":"230","article-title":"Guidelines on the management of valvular heart disease: the Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology","volume":"28","author":"Vahanian","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib6","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1093\/eurheartj\/ehm001","article-title":"What are the characteristics of patients with severe, symptomatic, mitral regurgitation who are denied surgery?","volume":"28","author":"Mirabel","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib7","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1161\/01.CIR.91.4.1022","article-title":"Valve repair improves the outcome of surgery for mitral regurgitation","volume":"91","author":"Enriquez-Sarano","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2011.09.013_bib8","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.athoracsur.2004.04.003","article-title":"Selecting patients with mitral regurgitation and left ventricular dysfunction for isolated mitral valve surgery","volume":"78","author":"Haan","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jcin.2011.09.013_bib9","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1161\/01.CIR.99.3.400","article-title":"Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation: rationale for optimizing surgical indications","volume":"99","author":"Tribouilloy","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2011.09.013_bib10","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1067\/mtc.2001.117277","article-title":"The double-orifice technique in mitral valve repair: a simple solution for complex problems","volume":"122","author":"Alfieri","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jcin.2011.09.013_bib11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.jacc.2009.03.077","article-title":"Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort","volume":"54","author":"Feldman","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib12","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/eurheartj\/ehq050","article-title":"Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction","volume":"31","author":"Franzen","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib13","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/eurheartj\/ehq051","article-title":"Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting","volume":"31","author":"Tamburino","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib14","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/BF03091811","article-title":"Percutaneous mitral valve repair using the edge-to-edge technique in a high-risk population","volume":"18","author":"Van den Branden","year":"2010","journal-title":"Neth Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib15","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1093\/ejechocard\/jep101","article-title":"Three-dimensional transoesophageal echocardiography in a patient undergoing percutaneous mitral valve repair using the edge-to-edge clip technique","volume":"10","author":"Swaans","year":"2009","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.jcin.2011.09.013_bib16","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","article-title":"Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography","volume":"16","author":"Zoghbi","year":"2003","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.jcin.2011.09.013_bib17","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.amjcard.2007.06.066","article-title":"Quantitative assessment of severity of mitral regurgitation by serial echocardiography in a multicenter clinical trial of percutaneous mitral valve repair","volume":"100","author":"Foster","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib18","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/S0002-9149(02)03301-5","article-title":"Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure","volume":"91","author":"Trichon","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib19","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1093\/eurheartj\/ehq411","article-title":"Ischaemic mitral regurgitation: pathophysiology, outcomes and the conundrum of treatment","volume":"31","author":"Pi\u00e9rard","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2011.09.013_bib20","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.jacc.2007.02.043","article-title":"Impact of mitral valve annuloplasty combined with revascularization in patients with functional ischemic mitral regurgitation","volume":"49","author":"Mihaljevic","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib21","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1055\/s-2008-1038420","article-title":"Early and late results of restrictive mitral valve annuloplasty in 121 patients with cardiomyopathy and chronic mitral regurgitation","volume":"56","author":"Geidel","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jcin.2011.09.013_bib22","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.athoracsur.2003.12.035","article-title":"Multivariable prediction of in-hospital mortality associated with aortic and mitral valve surgery in Northern New England","volume":"77","author":"Nowicki","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jcin.2011.09.013_bib23","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jacc.2009.08.059","article-title":"Mitral valve surgery in advanced heart failure","volume":"55","author":"Di Salvo","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib24","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S0735-1097(96)00281-1","article-title":"Left ventricular function after valve repair for chronic mitral regurgitation: predictive value of preoperative assessment of contractile reserve by exercise echocardiography","volume":"28","author":"Leung","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib25","first-page":"340","article-title":"The prognostic value of stress tests in chronic heart failure","volume":"14","author":"Piechota","year":"2007","journal-title":"Cardiol J"},{"key":"10.1016\/j.jcin.2011.09.013_bib26","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1009355","article-title":"Percutaneous repair or surgery for mitral regurgitation","volume":"364","author":"Feldman","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2011.09.013_bib27","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1093\/eurjhf\/hfr029","article-title":"MitraClip\u00ae therapy in patients with end-stage systolic heart failure","volume":"13","author":"Franzen","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2011.09.013_bib28","first-page":"181","article-title":"Surgical isolated edge-to-edge mitral valve repair without annuloplasty: clinical proof of the principle for an endovascular approach","volume":"2","author":"Maisano","year":"2006","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2011.09.013_bib29","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.athoracsur.2004.03.022","article-title":"Repair of ischemic mitral regurgitation does not increase mortality or improve long-term survival in patients undergoing coronary artery revascularization: a propensity analysis","volume":"78","author":"Diodato","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jcin.2011.09.013_bib30","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jacc.2004.09.073","article-title":"Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction","volume":"45","author":"Wu","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib31","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.jacc.2009.03.079","article-title":"Failure of guideline adherence for intervention in patients with severe mitral regurgitation","volume":"54","author":"Bach","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2011.09.013_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcin.2010.09.023","article-title":"Percutaneous transcatheter mitral valve repair: a classification of the technology","volume":"4","author":"Chiam","year":"2011","journal-title":"J Am Coll Cardiol Intv"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879811007886?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879811007886?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:58:02Z","timestamp":1761847082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879811007886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S1936879811007886"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2011.09.013","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Percutaneous Edge-to-Edge Mitral Valve Repair in High-Surgical-Risk Patients","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2011.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}