{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:17:01Z","timestamp":1773155821052,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":417,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100008897","name":"Janssen Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.jcin.2012.03.022","type":"journal-article","created":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T12:37:32Z","timestamp":1342615052000},"page":"718-727","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":111,"title":["Drug-Eluting Stent for Left Main Coronary Artery Disease"],"prefix":"10.1016","volume":"5","author":[{"given":"Alaide","family":"Chieffo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Meliga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinobu","family":"Onuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piera","family":"Capranzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Valgimigli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanda","family":"Jegere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj R.","family":"Makkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor F.","family":"Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Hak","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawel E.","family":"Buszman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarun","family":"Chakravarty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imad","family":"Sheiban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Naber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronan","family":"Margey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arvind","family":"Agnihotri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Marra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Capodanno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin B.","family":"Leon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey W.","family":"Moses","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Fajadet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Lefevre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Claude","family":"Morice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrejs","family":"Erglis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Tamburino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio","family":"Alfieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick W.","family":"Serruys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2012.03.022_bib1","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1016\/j.jacc.2009.10.015","volume":"54","author":"Kushner","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib2","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1161\/01.CIR.0000155256.88940.F8","article-title":"Early and mid-term results of drug-eluting stent implantation in unprotected left main","volume":"111","author":"Chieffo","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2012.03.022_bib3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.ahj.2004.03.011","article-title":"Rapamycin-eluting stents for the treatment of unprotected left main coronary disease","volume":"148","author":"de Lezo","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2012.03.022_bib4","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.amjcard.2007.10.052","article-title":"Effectiveness of drug-eluting stent implantation for patients with unprotected left main coronary artery stenosis","volume":"101","author":"Kim","year":"2008","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib5","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.jacc.2005.09.072","article-title":"Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug-eluting stents for unprotected left main coronary artery disease","volume":"47","author":"Lee","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib6","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.amjcard.2008.07.030","article-title":"Two-year clinical outcome with drug-eluting stents versus bare-metal stents in a real-world registry of unprotected left main coronary artery stenosis from the Italian Society of Invasive Cardiology","volume":"102","author":"Palmerini","year":"2008","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jacc.2004.10.039","article-title":"Sirolimus-eluting stent implantation for unprotected left main coronary artery stenosis: comparison with bare metal stent implantation","volume":"45","author":"Park","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib8","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.jacc.2005.12.015","article-title":"Serial angiographic follow-up of sirolimus-eluting stents for unprotected left main coronary artery revascularization","volume":"47","author":"Price","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib9","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.amjcard.2007.03.041","article-title":"Long-term clinical and angiographic outcomes of treatment of unprotected left main coronary artery stenosis with sirolimus-eluting stents","volume":"100","author":"Sheiban","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib10","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.jacc.2005.09.040","article-title":"Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis","volume":"47","author":"Valgimigli","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.amjcard.2007.08.054","article-title":"Comparison of percutaneous versus surgical revascularization of severe unprotected left main coronary stenosis in matched patients","volume":"101","author":"Brener","year":"2008","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib12","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jacc.2007.09.054","article-title":"Acute and late outcomes of unprotected left main stenting in comparison with surgical revascularization","volume":"51","author":"Buszman","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib13","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.jcin.2010.03.014","article-title":"5-year outcomes following percutaneous coronary intervention with drug-eluting stent implantation versus coronary artery bypass graft for unprotected left main coronary artery lesions the Milan experience","volume":"3","author":"Chieffo","year":"2010","journal-title":"J Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2012.03.022_bib14","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1016\/j.jacc.2008.03.020","article-title":"Longest available clinical outcomes after drug-eluting stent implantation for unprotected left main coronary artery disease: the DELFT (drug eluting stent for LeFT main) registry","volume":"51","author":"Meliga","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib15","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/j.jacc.2010.03.097","volume":"56","author":"Park","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jacc.2010.04.004","volume":"56","author":"Park","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib17","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/eurheartj\/ehp052","article-title":"Are drug-eluting stents superior to bare-metal stents in patients with unprotected non-bifurcational left main disease?","volume":"30","author":"Tamburino","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2012.03.022_bib18","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.amjcard.2008.08.059","article-title":"Comparison of drug-eluting stents and bare-metal stents for the treatment of unprotected left main coronary artery disease in acute coronary syndromes","volume":"103","author":"Tamburino","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib19","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1056\/NEJMoa0804626","article-title":"Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease","volume":"360","author":"Serruys","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2012.03.022_bib20","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.jacc.2009.07.007","article-title":"Early and long-term results of unprotected left main coronary artery stenting: the LE MANS (Left Main Coronary Artery Stenting) registry","volume":"54","author":"Buszman","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib21","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: a case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2012.03.022_bib22","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1161\/CIRCULATIONAHA.105.595694","article-title":"Percutaneous treatment with drug-eluting stent implantation versus bypass surgery for unprotected left main stenosis: a single-center experience","volume":"113","author":"Chieffo","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2012.03.022_bib23","first-page":"219","article-title":"The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease","volume":"1","author":"Sianos","year":"2005","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2012.03.022_bib24","first-page":"356","article-title":"Sirolimus-eluting stents vs bare metal stents for the treatment of unprotected left main coronary artery stenosis","volume":"2","author":"Sheiban","year":"2006","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2012.03.022_bib25","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1056\/NEJMoa1100452","article-title":"Randomized trial of stents versus bypass surgery for left main coronary artery disease","volume":"364","author":"Park","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2012.03.022_bib26","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jacc.2010.09.038","article-title":"Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis","volume":"57","author":"Boudriot","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2012.03.022_bib27","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1056\/NEJMoa0801441","article-title":"Stents versus coronary-artery bypass grafting for left main coronary artery disease","volume":"358","author":"Seung","year":"2008","journal-title":"N Engl J Med"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879812004268?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879812004268?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:58:03Z","timestamp":1761847083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879812004268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1936879812004268"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2012.03.022","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drug-Eluting Stent for Left Main Coronary Artery Disease","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2012.03.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}