{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T06:22:23Z","timestamp":1774419743521,"version":"3.50.1"},"reference-count":18,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T00:00:00Z","timestamp":1422835200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.jcin.2013.10.016","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T16:17:43Z","timestamp":1392653863000},"page":"140-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Usefulness of Baseline Activated Clotting Time\u2013Guided Heparin Administration in Reducing Bleeding Events During Transfemoral Transcatheter Aortic Valve Implantation"],"prefix":"10.1016","volume":"7","author":[{"given":"Chiara","family":"Bernelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaide","family":"Chieffo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Montorfano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Maisano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gennaro","family":"Giustino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gill Louise","family":"Buchanan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaclyn","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charis","family":"Costopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Figini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ermelinda","family":"De Meo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remo Daniel","family":"Covello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Gerli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalisa","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eustachio","family":"Agricola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Spagnolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micaela","family":"Cioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio","family":"Alfieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo Guido","family":"Camici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2013.10.016_bib1","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","article-title":"Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery","volume":"363","author":"Leon","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2013.10.016_bib2","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1056\/NEJMoa1200384","article-title":"Two-year outcomes after transcatheter or surgical aortic-valve replacement","volume":"366","author":"Kodali","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2013.10.016_bib3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jacc.2010.12.005","article-title":"Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium","volume":"57","author":"Leon","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib4","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1016\/j.jacc.2012.02.022","article-title":"Clinical outcomes after transcatheter aortic valve replacement using Valve Academic Research Consortium definitions: a weighted meta-analysis of 3,519 patients from 16 studies","volume":"59","author":"G\u00e9n\u00e9reux","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib5","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.ahj.2012.07.003","article-title":"Adverse impact of bleeding and transfusion on the outcome post-transcatheter aortic valve implantation: insights from the Pooled-RotterdAm-Milano-Toulouse In Collaboration Plus (PRAGMATIC Plus) initiative","volume":"164","author":"Tchetche","year":"2012","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2013.10.016_bib6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1056\/NEJMoa022831","article-title":"Acquired von Willebrand syndrome in aortic stenosis","volume":"349","author":"Vincentelli","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2013.10.016_bib7","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.jacc.2012.01.001","article-title":"2012 ACCF\/AATS\/SCAI\/STS expert consensus document on transcatheter aortic valve replacement","volume":"59","author":"Holmes","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib8","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3810\/pgm.2013.01.2625","article-title":"A\u00a0review of antithrombotic therapy for transcatheter aortic valve replacement","volume":"125","author":"Davis","year":"2013","journal-title":"Postgrad Med"},{"key":"10.1016\/j.jcin.2013.10.016_bib9","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.jcin.2010.09.012","article-title":"Outcomes after transcatheter aortic valve implantation with both Edwards-SAPIEN and CoreValve devices in a single center: the Milan experience","volume":"3","author":"Godino","year":"2010","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2013.10.016_bib10","doi-asserted-by":"crossref","first-page":"556","DOI":"10.4244\/EIJV7I5A91","article-title":"The role of sex on VARC outcomes following transcatheter aortic valve implantation with both Edwards SAPIEN and Medtronic CoreValve ReValving System devices: the Milan registry","volume":"7","author":"Buchanan","year":"2011","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2013.10.016_bib11","first-page":"784","article-title":"A\u00a0new technique for vascular access management in transcatheter aortic valve implantation","volume":"75","author":"Sharp","year":"2010","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2013.10.016_bib12","first-page":"156","article-title":"A\u00a0comparison of the femoral and radial crossover techniques for vascular access management in transcatheter aortic valve implantation: the Milan experience","volume":"83","author":"Curran","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2013.10.016_bib13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.amjcard.2012.09.023","article-title":"Managing patients with an indication for anticoagulant therapy after transcatheter aortic valve implantation","volume":"111","author":"Figini","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib14","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.jacc.2012.09.001","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"60","author":"Kappetein","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib15","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.jacc.2013.03.029","article-title":"Antithrombotic treatment in transcatheter aortic valve implantation: insights for cerebrovascular and bleeding events","volume":"62","author":"Rod\u00e9s-Cabau","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jacc.2011.06.074","article-title":"Optimizing transcatheter aortic valve sizing and minimizing vascular complications","volume":"59","author":"Ruiz","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2013.10.016_bib17","first-page":"70","article-title":"Safety and feasibility of bivalirudin with either Cypher and Taxus drug-eluting stent during percutaneous coronary intervention","volume":"1","author":"Chieffo","year":"2005","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2013.10.016_bib18","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1007\/s11239-013-0886-z","article-title":"Considerations in antithrombotic therapy among patients undergoing transcatheter aortic valve implantation","volume":"35","author":"Lynch","year":"2013","journal-title":"J\u00a0Thromb Thrombolysis"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879813017020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879813017020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:59:49Z","timestamp":1761847189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879813017020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S1936879813017020"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2013.10.016","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Usefulness of Baseline Activated Clotting Time\u2013Guided Heparin Administration in Reducing Bleeding Events During Transfemoral Transcatheter Aortic Valve Implantation","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2013.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}