{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:05:14Z","timestamp":1792091114131,"version":"4.4.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T00:00:00Z","timestamp":1525737600000},"content-version":"vor","delay-in-days":372,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.jcin.2016.12.280","type":"journal-article","created":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T14:16:02Z","timestamp":1493648162000},"page":"931-939","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":193,"title":["Elevated Mitral Valve Pressure Gradient After MitraClip Implantation Deteriorates Long-Term Outcome in Patients With Severe Mitral Regurgitation and Severe\u00a0Heart Failure"],"prefix":"10.1016","volume":"10","author":[{"given":"Michael","family":"Neuss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Isotani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Pilz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Sch\u00f6pp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Butter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2016.12.280_bib1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ahj.2010.04.009","article-title":"The EVEREST II trial: design and rationale for a randomized study of the evalve MitraClip system compared with mitral valve surgery for mitral regurgitation","volume":"160","author":"Mauri","year":"2010","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2016.12.280_bib2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jacc.2013.04.030","article-title":"4-year results of randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation","volume":"62","author":"Mauri","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2016.12.280_bib3","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00392-013-0614-x","article-title":"Percutaneous interventional mitral regurgitation treatment using the Mitra-Clip system","volume":"103","author":"Boekstegers","year":"2014","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jcin.2016.12.280_bib4","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/eurheartj\/ehq050","article-title":"Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction","volume":"31","author":"Franzen","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2016.12.280_bib5","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/eurheartj\/ehq051","article-title":"Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting","volume":"31","author":"Tamburino","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2016.12.280_bib6","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1016\/j.jacc.2011.07.047","article-title":"Echocardiographic and clinical outcomes of MitraClip therapy in patients not amenable to surgery","volume":"58","author":"Rudolph","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2016.12.280_bib7","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.jacc.2013.02.094","article-title":"Percutaneous mitral valve interventions in the real world: early and 1-year results from the ACCESS-EU, a prospective, multicenter, nonrandomized post-approval study of the MitraClip therapy in Europe","volume":"62","author":"Maisano","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2016.12.280_bib8","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/eurjhf\/hft046","article-title":"One year clinical efficacy and reverse cardiac remodeling and reduced ejection fraction after MitraClip implantation","volume":"15","author":"Pleger","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2016.12.280_bib9","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1093\/eurjhf\/hfs214","article-title":"Patient selection criteria and midterm clinical outcome\u00a0for MitraClip therapy in patients with severe mitral regurgitation and severe congestive heart failure","volume":"15","author":"Neuss","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2016.12.280_bib10","doi-asserted-by":"crossref","first-page":"e000056","DOI":"10.1136\/openhrt-2014-000056","article-title":"Two-year outcomes after percutaneous mitral valve repair with the MitraClip system: durability of the procedure and predictors of outcome","volume":"1","author":"Toggweiler","year":"2014","journal-title":"Open Heart"},{"key":"10.1016\/j.jcin.2016.12.280_bib11","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","article-title":"Recommendations for evaluation of the\u00a0severity of native valvular regurgitation with two-dimensional and Doppler echocardiography","volume":"16","author":"Zoghbi","year":"2003","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcin.2016.12.280_bib12","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.amjcard.2007.06.066","article-title":"Quantitative assessment of severity of mitral regurgitation by serial echocardiography in a\u00a0multicenter clinical trial of percutaneous mitral valve repair","volume":"100","author":"Foster","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2016.12.280_bib13","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1161\/CIRCIMAGING.113.000620","article-title":"Assessment of mitral valve area during percutaneous mitral valve repair using the MitraClip system: comparison of different echocardiographic methods","volume":"6","author":"Biaggi","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jcin.2016.12.280_bib14","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1093\/eurjhf\/hfs079","article-title":"MitraClip therapy in daily clinical practice: initial results from the German transcatheter mitral valve interventions (TRAMI) registry","volume":"14","author":"Baldus","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2016.12.280_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.echo.2013.09.007","article-title":"Mitral inflow patterns after MitraClip implantation at rest and during exercise","volume":"27","author":"Boelage-van Dijk","year":"2014","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcin.2016.12.280_bib16","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.echo.2014.06.001","article-title":"Percutaneous mitral valve repair preserves right ventricular function","volume":"27","author":"Van Riel","year":"2014","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcin.2016.12.280_bib17","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1177\/0218492315598240","article-title":"Intermediate outcomes of rheumatic mitral stenosis post-balloon mitral valvotomy","volume":"23","author":"Sharma","year":"2015","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"10.1016\/j.jcin.2016.12.280_bib18","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/j.jtcvs.2013.08.011","article-title":"Clinical evaluation of functional mitral stenosis after mitral valve repair for degenerative disease: potential affect on surgical strategy","volume":"146","author":"Measana","year":"2013","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jcin.2016.12.280_bib19","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1177\/0218492315576282","article-title":"Mitral valve repair for rheumatic mitral regurgitation: mid-term results","volume":"23","author":"Waikittipong","year":"2015","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"10.1016\/j.jcin.2016.12.280_bib20","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.jacc.2014.11.037","article-title":"Mitral valve area during exercise after restrictive mitral valve annuloplasty: importance of diastolic anterior leaflet tethering","volume":"65","author":"Bertrand","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879817301450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879817301450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:05:24Z","timestamp":1761847524000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879817301450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S1936879817301450"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2016.12.280","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevated Mitral Valve Pressure Gradient After MitraClip Implantation Deteriorates Long-Term Outcome in Patients With Severe Mitral Regurgitation and Severe\u00a0Heart Failure","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2016.12.280","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}