{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:56:19Z","timestamp":1789829779213,"version":"4.0.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T00:00:00Z","timestamp":1592956800000},"content-version":"vor","delay-in-days":389,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jcin.2019.03.012","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T14:26:16Z","timestamp":1560781576000},"page":"1140-1149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Bleeding Complications in Lower-Extremity Peripheral Vascular\u00a0Interventions"],"prefix":"10.1016","volume":"12","author":[{"given":"Bhaskar","family":"Bhardwaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin F.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Schuyler","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Safley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas T.","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert D.","family":"Aronow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit N.","family":"Vora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashashwi","family":"Pokharel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R.","family":"Attaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitriy N.","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehrin","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Salisbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2019.03.012_bib1","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1001\/jama.2013.1556","article-title":"Association between bleeding events and in-hospital mortality after percutaneous coronary intervention","volume":"309","author":"Chhatriwalla","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jcin.2019.03.012_bib2","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1016\/j.jacc.2008.12.073","article-title":"Bleeding, blood transfusion, and increased mortality after percutaneous coronary intervention: implications for contemporary practice","volume":"53","author":"Doyle","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib3","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.jcin.2009.09.002","article-title":"Prognostic impact of periprocedural bleeding and myocardial infarction after percutaneous coronary intervention in unselected patients: results from the EVENT (evaluation of drug-eluting stents and ischemic events) registry","volume":"2","author":"Lindsey","year":"2009","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.03.012_bib4","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.jacc.2007.02.027","article-title":"Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial","volume":"49","author":"Manoukian","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib5","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1001\/jama.2010.708","article-title":"Association between use of bleeding avoidance strategies and risk of periprocedural bleeding among patients undergoing percutaneous coronary intervention","volume":"303","author":"Marso","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.jcin.2019.03.012_bib6","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1161\/CIRCINTERVENTIONS.108.846741","article-title":"Bleeding in patients undergoing percutaneous coronary intervention: the development of a clinical risk algorithm from the National Cardiovascular Data Registry","volume":"2","author":"Mehta","year":"2009","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2019.03.012_bib7","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.jacc.2007.10.040","article-title":"Periprocedural bleeding and 1-year outcome after percutaneous coronary interventions: appropriateness of including bleeding as a component of a quadruple end point","volume":"51","author":"Ndrepepa","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib8","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jcin.2013.04.016","article-title":"An updated bleeding model to predict the risk of post-procedure bleeding among patients undergoing percutaneous coronary intervention: a report using an expanded bleeding definition from the National Cardiovascular Data Registry CathPCI: Registry","volume":"6","author":"Rao","year":"2013","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.03.012_bib9","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.amjcard.2005.06.056","article-title":"Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes","volume":"96","author":"Rao","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib10","doi-asserted-by":"crossref","first-page":"h1302","DOI":"10.1136\/bmj.h1302","article-title":"Precision medicine to improve use of bleeding avoidance strategies and reduce bleeding in patients undergoing percutaneous coronary intervention: prospective cohort study before and after implementation of personalized bleeding risks","volume":"350","author":"Spertus","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.jcin.2019.03.012_bib11","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.jvs.2004.09.024","article-title":"Predictors of complications after a prospective evaluation of diagnostic and therapeutic endovascular procedures","volume":"40","author":"Danetz","year":"2004","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jcin.2019.03.012_bib12","first-page":"599","article-title":"Preprocedural hemoglobin predicts mortality following peripheral vascular interventions","volume":"78","author":"Jaffery","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2019.03.012_bib13","first-page":"401","article-title":"Bivalirudin in peripheral vascular interventions: a single center experience","volume":"15","author":"Shammas","year":"2003","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib14","first-page":"242","article-title":"In-hospital complications of peripheral vascular interventions using unfractionated heparin as the primary anticoagulant","volume":"15","author":"Shammas","year":"2003","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib15","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.jcin.2009.06.015","article-title":"Comparison of safety and efficacy of bivalirudin versus unfractionated heparin in percutaneous peripheral intervention: a single-center experience","volume":"2","author":"Sheikh","year":"2009","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.03.012_bib17","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.amjcard.2010.12.009","article-title":"In-hospital major bleeding during ST-elevation and non-ST-elevation myocardial infarction care: derivation and validation of a model from the ACTION Registry(R)-GWTG","volume":"107","author":"Mathews","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jvs.2009.01.035","article-title":"National trends in lower extremity bypass surgery, endovascular interventions, and major amputations","volume":"50","author":"Goodney","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jcin.2019.03.012_bib19","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.jvs.2008.11.054","article-title":"Patterns of treatment for peripheral arterial disease in the United States: 1996-2005","volume":"49","author":"Rowe","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jcin.2019.03.012_bib20","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1161\/CIRCULATIONAHA.110.009449","article-title":"Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium","volume":"123","author":"Mehran","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2019.03.012_bib21","first-page":"35","article-title":"Association of anemia with outcomes in patients undergoing percutaneous peripheral vascular intervention: insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2 VIC)","volume":"30","author":"Ambulgekar","year":"2018","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib22","doi-asserted-by":"crossref","first-page":"e0165796","DOI":"10.1371\/journal.pone.0165796","article-title":"The association of peri-procedural blood transfusion with morbidity and mortality in patients undergoing percutaneous lower extremity vascular interventions: insights from BMC2 VIC","volume":"11","author":"Henke","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jcin.2019.03.012_bib23","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jvs.2009.03.041","article-title":"Preprocedural hemoglobin predicts outcome in peripheral vascular disease patients undergoing percutaneous transluminal angioplasty","volume":"50","author":"Toor","year":"2009","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jcin.2019.03.012_bib24","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1161\/CIRCINTERVENTIONS.114.001306","article-title":"Access site complications after peripheral vascular interventions: incidence, predictors, and outcomes","volume":"7","author":"Ortiz","year":"2014","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2019.03.012_bib25","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1016\/j.jacc.2016.11.007","article-title":"2016 AHA\/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"69","author":"Gerhard-Herman","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib26","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0735-1097(02)01745-X","article-title":"The impact of renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary interventions","volume":"39","author":"Best","year":"2002","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib27","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1016\/j.jacc.2014.03.036","article-title":"Impact of sex on morbidity and mortality rates after lower extremity interventions for peripheral arterial disease: observations from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium","volume":"63","author":"Jackson","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib28","first-page":"433","article-title":"Impact of gender on in-hospital outcomes following contemporary percutaneous intervention for peripheral arterial disease","volume":"17","author":"Kawamura","year":"2005","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib29","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.jacc.2013.03.086","article-title":"Impact of periprocedural bleeding on incidence of contrast-induced acute kidney injury in patients treated with percutaneous coronary intervention","volume":"62","author":"Ohno","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.03.012_bib30","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.jcin.2011.03.012","article-title":"Safety of contemporary percutaneous peripheral arterial interventions in the elderly insights from the BMC2 PVI (Blue Cross Blue Shield of Michigan Cardiovascular Consortium Peripheral Vascular Intervention) registry","volume":"4","author":"Plaisance","year":"2011","journal-title":"J Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.03.012_bib31","doi-asserted-by":"crossref","first-page":"e004439","DOI":"10.1161\/CIRCINTERVENTIONS.116.004439","article-title":"Longitudinal risk of adverse events in patients with acute kidney injury after percutaneous coronary intervention: insights from the National Cardiovascular Data Registry","volume":"10","author":"Valle","year":"2017","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2019.03.012_bib32","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/j.jvs.2010.05.106","article-title":"Lessons learned from the analysis of gender effect on risk factors and procedural outcomes of lower extremity arterial disease","volume":"52","author":"Vouyouka","year":"2010","journal-title":"J\u00a0Vasc Surg"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879819306843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879819306843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:09:23Z","timestamp":1761847763000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879819306843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S1936879819306843"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2019.03.012","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bleeding Complications in Lower-Extremity Peripheral Vascular\u00a0Interventions","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2019.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}