{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:50:22Z","timestamp":1790891422479,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"24","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"vor","delay-in-days":388,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.jcin.2019.09.046","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T16:37:09Z","timestamp":1576514229000},"page":"2488-2495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":141,"title":["Compassionate Use of the PASCAL Transcatheter Valve Repair System for Severe Tricuspid Regurgitation"],"prefix":"10.1016","volume":"12","author":[{"given":"Neil P.","family":"Fam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph Stephan","family":"von Bardeleben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Nabauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Ruf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim A.","family":"Connelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Thiele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Lurz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Nickenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhil","family":"Narang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles J.","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Hausleiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2019.09.046_bib1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jacc.2003.09.036","article-title":"Impact of tricuspid regurgitation on long-term survival","volume":"43","author":"Nath","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jcmg.2018.06.014","article-title":"Burden of tricuspid regurgitation in patients diagnosed in the community setting","volume":"12","author":"Toplisky","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcin.2019.09.046_bib3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/eurheartj\/ehv627","article-title":"One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry","volume":"37","author":"Puls","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2019.09.046_bib4","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/eurheartj\/ehy641","article-title":"Tricuspid regurgitation is associated with increased mortality independent of pulmonary pressures and right heart failure: a systematic review and meta-analysis","volume":"40","author":"Wang","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2019.09.046_bib5","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ehjci\/jet105","article-title":"Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcin.2019.09.046_bib6","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1016\/j.jacc.2014.02.537","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib7","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2019.09.046_bib8","article-title":"Contemporary trends in the use and outcomes of surgical treatment of tricuspid regurgitation","volume":"6","author":"Alqahtani","year":"2017","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jcin.2019.09.046_bib9","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1016\/j.jacc.2017.10.039","article-title":"National trends and outcomes in isolated tricuspid valve surgery","volume":"70","author":"Zack","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib10","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.jacc.2019.04.028","article-title":"Surgery does not improve survival in patients with isolated severe tricuspid regurgitation","volume":"74","author":"Axtell","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.jacc.2009.03.077","article-title":"Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge Repair Study) cohort","volume":"54","author":"Feldman","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib12","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jacc.2013.04.030","article-title":"4-Year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation","volume":"62","author":"Mauri","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib13","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1093\/eurjhf\/hfr029","article-title":"MitraClip\u00ae therapy in patients with end-stage systolic heart failure","volume":"13","author":"Franzen","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2019.09.046_bib14","first-page":"137","article-title":"Percutaneous edge-to-edge repair of the mitral valve in patients with degenerative versus functional mitral regurgitation","volume":"84","author":"Braun","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2019.09.046_bib15","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00059-013-3857-4","article-title":"[Interventional mitral valve repair with the MitraClip\u00ae procedure. Patient selection criteria]","volume":"38","author":"Braun","year":"2013","journal-title":"Herz"},{"key":"10.1016\/j.jcin.2019.09.046_bib16","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/joic.12193","article-title":"Long-term outcome of patients with severe biventricular heart failure and severe mitral regurgitation after percutaneous edge-to-edge mitral valve repair","volume":"28","author":"Orban","year":"2015","journal-title":"J\u00a0Interv Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib17","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1056\/NEJMoa1806640","article-title":"Transcatheter mitral-valve repair in patients with heart failure","volume":"379","author":"Stone","year":"2018","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2019.09.046_bib18","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1093\/eurheartj\/ehv710","article-title":"Transcatheter treatment of severe tricuspid regurgitation with the MitraClip system","volume":"37","author":"Hammerstingl","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2019.09.046_bib19","doi-asserted-by":"crossref","first-page":"e413","DOI":"10.4244\/EIJ-D-18-00186","article-title":"One-year results of transcatheter treatment of severe tricuspid regurgitation using the edge-to-edge repair technique","volume":"14","author":"Braun","year":"2018","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2019.09.046_bib20","doi-asserted-by":"crossref","first-page":"645","DOI":"10.4244\/EIJ-D-17-01136","article-title":"Patient selection, echocardiographic screening and treatment strategies for interventional tricuspid repair using the edge-to-edge repair technique","volume":"14","author":"Hausleiter","year":"2018","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2019.09.046_bib21","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1161\/CIRCULATIONAHA.116.024848","article-title":"Transcatheter treatment of severe tricuspid regurgitation with the edge-to-edge MitraClip technique","volume":"135","author":"Nickenig","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2019.09.046_bib22","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/ejhf.1147","article-title":"Six-month outcome after transcatheter edge-to-edge repair of severe tricuspid regurgitation in patients with heart failure","volume":"20","author":"Orban","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jcin.2019.09.046_bib23","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.jcin.2018.05.002","article-title":"Predictors of procedural and clinical outcomes in patients with symptomatic tricuspid regurgitation undergoing transcatheter edge-to-edge repair","volume":"11","author":"Besler","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib24","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0140-6736(17)31600-8","article-title":"Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study","volume":"390","author":"Praz","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.jcin.2019.09.046_bib25","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.jcin.2019.04.034","article-title":"Transcatheter valve repair for patients with mitral regurgitation: 30-day results of the CLASP study","volume":"12","author":"Lim","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib26","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jcin.2017.12.004","article-title":"Transcatheter tricuspid valve repair with the PASCAL system","volume":"11","author":"Fam","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib27","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.jcin.2019.09.046_bib28","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","article-title":"Recommendations for evaluation of the severity\u00a0of\u00a0native valvular regurgitation with two-dimensional and Doppler echocardiography","volume":"16","author":"Zoghbi","year":"2003","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcin.2019.09.046_bib29","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1093\/ehjci\/jex139","article-title":"The need for a new tricuspid regurgitation grading scheme","volume":"18","author":"Hahn","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcin.2019.09.046_bib30","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.jcin.2017.08.011","article-title":"The international multicenter TriValve registry: which patients are undergoing transcatheter tricuspid repair?","volume":"10","author":"Taramasso","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib31","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcin.2018.10.022","article-title":"Outcomes after current transcatheter tricuspid valve intervention: mid-term results from the international TriValve registry","volume":"12","author":"Taramasso","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib32","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/j.jcin.2019.04.019","article-title":"1-Year outcomes after edge-to-edge valve repair for symptomatic tricuspid regurgitation: results from the TriValve registry","volume":"12","author":"Hausleiter","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib33","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.jcin.2018.11.028","article-title":"Acute and short-term results of transcatheter edge-to-edge repair for severe tricuspid regurgitation using the MitraClip XTR system","volume":"12","author":"Braun","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2019.09.046_bib34","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/HCO.0000000000000607","article-title":"Transcatheter tricuspid valve intervention: a practical algorithm for patient selection","volume":"34","author":"Ho","year":"2019","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib35","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.jacc.2017.09.015","article-title":"Outcomes with transcatheter mitral valve repair in the United States: an STS\/ACC TVT registry report","volume":"70","author":"Sorajja","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2019.09.046_bib36","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/j.jacc.2017.01.054","article-title":"Early feasibility study of a transcatheter tricuspid annuloplasty: SCOUT trial 30-day results","volume":"69","author":"Hahn","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879819320606?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879819320606?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:10:34Z","timestamp":1761847834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879819320606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":36,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S1936879819320606"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2019.09.046","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Compassionate Use of the PASCAL Transcatheter Valve Repair System for Severe Tricuspid Regurgitation","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2019.09.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}