{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T03:21:40Z","timestamp":1776223300802,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:00:00Z","timestamp":1656374400000},"content-version":"vor","delay-in-days":392,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.jcin.2021.04.003","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T14:17:26Z","timestamp":1622038646000},"page":"1308-1319","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["In-Stent CTO Percutaneous Coronary\u00a0Intervention"],"prefix":"10.1016","volume":"14","author":[{"given":"Evangelia","family":"Vemmou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre S.","family":"Quadros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph A.","family":"Dens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidal Abi","family":"Rafeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierfrancesco","family":"Agostoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaldoon","family":"Alaswad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Avran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karlyse C.","family":"Belli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Carlino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James W.","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"El-Guindy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farouc A.","family":"Jaffer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitri","family":"Karmpaliotis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaikirshan J.","family":"Khatri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dmitrii","family":"Khelimskii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Knaapen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"La Manna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleg","family":"Krestyaninov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Lamelas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soledad","family":"Ojeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucio","family":"Padilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Piccaro de Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Rinfret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Spratt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Tanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilias","family":"Nikolakopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Karacsonyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bavana V.","family":"Rangan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouil S.","family":"Brilakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Azzalini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2021.04.003_bib1","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/j.amjcard.2005.01.098","article-title":"Success, safety, and mechanisms of failure of percutaneous coronary intervention for occlusive non-drug-eluting in-stent restenosis versus native artery total occlusion","volume":"95","author":"Abbas","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib2","first-page":"646","article-title":"The efficacy of \u201chybrid\u201d percutaneous coronary intervention in chronic total occlusions caused by in-stent restenosis: insights from a US multicenter registry","volume":"84","author":"Christopoulos","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2021.04.003_bib3","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1016\/j.jcin.2020.05.003","article-title":"Outcomes of percutaneous coronary intervention for in-stent chronic total occlusions: insights from the PROGRESS-CTO registry","volume":"13","author":"Vemmou","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib4","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.jcin.2017.01.047","article-title":"Procedural and long-term outcomes of percutaneous coronary intervention for in-stent chronic total occlusion","volume":"10","author":"Azzalini","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib5","doi-asserted-by":"crossref","first-page":"e219","DOI":"10.4244\/EIJ-D-16-00764","volume":"13","author":"de la Torre Hernandez","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2021.04.003_bib6","doi-asserted-by":"crossref","first-page":"e472","DOI":"10.4244\/EIJ-D-19-00650","article-title":"Clinical outcomes after percutaneous coronary intervention for in-stent chronic total occlusion","volume":"16","author":"Yoon","year":"2020","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2021.04.003_bib7","first-page":"E34","article-title":"In-stent chronic total occlusion angioplasty in the LATAM-CTO registry","volume":"97","author":"Lamelas","year":"2021","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2021.04.003_bib8","series-title":"Manual of Chronic Total Occlusion Interventions","first-page":"289","article-title":"Chapter 9\u2014complex lesion subsets","author":"Brilakis","year":"2018"},{"key":"10.1016\/j.jcin.2021.04.003_bib9","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.jacc.2012.08.001","article-title":"Third universal definition of myocardial infarction","volume":"60","author":"Thygesen","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jcin.2010.09.024","article-title":"Predicting successful guidewire crossing through chronic total occlusion of native coronary lesions within 30\u00a0minutes: the J-CTO (Multicenter CTO Registry in Japan) score as a difficulty grading and time assessment tool","volume":"4","author":"Morino","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcin.2015.09.022","article-title":"Development and validation of a novel scoring system for predicting technical success of chronic total occlusion percutaneous coronary interventions: the PROGRESS CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) score","volume":"9","author":"Christopoulos","year":"2016","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib12","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.jacc.2020.08.002","article-title":"Trends and outcomes of restenosis after coronary stent implantation in the United States","volume":"76","author":"Moussa","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib13","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.carrev.2010.08.002","article-title":"Contemporary outcomes of percutaneous intervention in chronic total coronary occlusions due to in-stent restenosis","volume":"12","author":"Abdel-Karim","year":"2011","journal-title":"Cardiovasc Revasc Med"},{"issue":"suppl D","key":"10.1016\/j.jcin.2021.04.003_bib14","first-page":"D79","article-title":"Management of total restenotic occlusions","volume":"5","author":"Werner","year":"2009","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2021.04.003_bib15","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/s00392-019-01550-7","article-title":"A\u00a0comparison of procedural success rate and long-term clinical outcomes between in-stent restenosis chronic total occlusion and de novo chronic total occlusion using multicenter registry data","volume":"109","author":"Lee","year":"2020","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib16","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1161\/CIRCULATIONAHA.119.039797","article-title":"Guiding principles for chronic total occlusion percutaneous coronary intervention","volume":"140","author":"Brilakis","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2021.04.003_bib17","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1016\/j.jcin.2020.04.052","article-title":"Long-term outcomes of coronary stenting with and without use of intravascular ultrasound","volume":"13","author":"Mentias","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib18","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.115.002592","article-title":"Clinical impact of intravascular ultrasound-guided chronic total occlusion intervention with zotarolimus-eluting versus biolimus-eluting stent implantation: randomized study","volume":"8","author":"Kim","year":"2015","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2021.04.003_bib19","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ahj.2019.12.008","article-title":"Impact of Intravascular Ultrasound on Outcomes Following Percutaneous Coronary Intervention in Complex Lesions (iOPEN Complex)","volume":"221","author":"Shlofmitz","year":"2020","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2021.04.003_bib20","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1016\/j.jcin.2016.06.057","article-title":"Utility of intravascular ultrasound in percutaneous revascularization of chronic total occlusions: an overview","volume":"9","author":"Galassi","year":"2016","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib21","first-page":"116","article-title":"The impact of age and sex on in-hospital outcomes of chronic total occlusion percutaneous coronary\u00a0intervention","volume":"29","author":"Karatasakis","year":"2017","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib22","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.007338","article-title":"In-hospital outcomes of chronic total occlusion percutaneous coronary interventions in patients with prior coronary artery bypass graft surgery","volume":"12","author":"Tajti","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2021.04.003_bib23","first-page":"310","article-title":"Long-term outcomes of percutaneous coronary intervention for chronic total occlusion in patients who have undergone coronary artery bypass grafting vs those who have not","volume":"34","author":"Azzalini","year":"2018","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.jcin.2021.04.003_bib24","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.jcin.2018.02.036","article-title":"The hybrid approach to chronic total occlusion percutaneous coronary intervention: update from the PROGRESS CTO registry","volume":"11","author":"Tajti","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcin.2021.04.003_bib25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1136\/heartjnl-2017-311986","article-title":"Predictors of successful chronic total occlusion percutaneous coronary interventions: a systematic review and meta-analysis","volume":"104","author":"Wang","year":"2018","journal-title":"Heart"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879821006774?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879821006774?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T18:13:53Z","timestamp":1761848033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879821006774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S1936879821006774"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2021.04.003","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In-Stent CTO Percutaneous Coronary\u00a0Intervention","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2021.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}