{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:28:50Z","timestamp":1792276130332,"version":"4.4.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":378,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.jcin.2024.07.016","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T18:25:11Z","timestamp":1726683911000},"page":"2216-2225","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Failed Thrombus Aspiration and Reduced Myocardial Perfusion in Patients With STEMI and Large Thrombus Burden"],"prefix":"10.1016","volume":"17","author":[{"given":"Ho Sung","family":"Jeon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young In","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0342-6360","authenticated-orcid":false,"given":"Jung-Hee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1461-5597","authenticated-orcid":false,"given":"Young Jun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Woo","family":"Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6206-1704","authenticated-orcid":false,"given":"Jun-Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Jin","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Soo","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jang-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Su","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Min","family":"Ko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Gyun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2024.07.016_bib1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2024.07.016_bib2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/MCA.0000000000000197","article-title":"The impact of initial and residual thrombus burden on the no-reflow phenomenon in patients with ST-segment elevation myocardial infarction","volume":"26","author":"Ahn","year":"2015","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.jcin.2024.07.016_bib3","doi-asserted-by":"crossref","first-page":"490","DOI":"10.4070\/kcj.2016.46.4.490","article-title":"Long-term clinical outcomes of transient and persistent no reflow phenomena following percutaneous coronary intervention in patients with acute myocardial infarction","volume":"46","author":"Kim","year":"2016","journal-title":"Korean Circ J"},{"key":"10.1016\/j.jcin.2024.07.016_bib4","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.jacc.2007.04.059","article-title":"Angiographic stent thrombosis after routine use of drug-eluting stents in ST-segment elevation myocardial infarction: the importance of thrombus burden","volume":"50","author":"Sianos","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2024.07.016_bib5","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/j.jacc.2018.07.047","article-title":"Thrombus aspiration in patients with high thrombus burden in the TOTAL trial","volume":"72","author":"Jolly","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2024.07.016_bib6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa0706416","article-title":"Thrombus aspiration during primary percutaneous coronary intervention","volume":"358","author":"Svilaas","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2024.07.016_bib7","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1016\/S0140-6736(08)60833-8","article-title":"Cardiac death and reinfarction after 1 year in the Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Myocardial Infarction Study (TAPAS): a 1-year follow-up study","volume":"371","author":"Vlaar","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.jcin.2024.07.016_bib8","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1056\/NEJMoa1308789","article-title":"Thrombus aspiration during ST-segment elevation myocardial infarction","volume":"369","author":"Frobert","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2024.07.016_bib9","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1056\/NEJMoa1415098","article-title":"Randomized trial of primary PCI with or without routine manual thrombectomy","volume":"372","author":"Jolly","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcin.2024.07.016_bib10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1001\/jamacardio.2018.4472","article-title":"Association of physician variation in use of manual aspiration thrombectomy with outcomes following primary percutaneous coronary intervention for ST-elevation myocardial infarction: the National Cardiovascular Data Registry CathPCI Registry","volume":"4","author":"Secemsky","year":"2019","journal-title":"JAMA Cardiol"},{"issue":"14","key":"10.1016\/j.jcin.2024.07.016_bib11","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","article-title":"2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"42","author":"Collet","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2024.07.016_bib12","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1161\/01.CIR.76.1.142","article-title":"Thrombolysis In Myocardial Infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge","volume":"76","author":"Chesebro","year":"1987","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2024.07.016_bib13","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1161\/01.CIR.0000065221.06430.ED","article-title":"Angiographic assessment of reperfusion in acute myocardial infarction by myocardial blush grade","volume":"107","author":"Henriques","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2024.07.016_bib14","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1161\/01.CIR.103.21.2550","article-title":"Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy","volume":"103","author":"Gibson","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2024.07.016_bib15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jcin.2012.11.011","article-title":"Relationship of thrombus characteristics to the incidence of angiographically visible distal embolization in patients with ST-segment elevation myocardial infarction treated with thrombus aspiration","volume":"6","author":"Yunoki","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2024.07.016_bib16","doi-asserted-by":"crossref","first-page":"760","DOI":"10.4244\/EIJV6I6A129","article-title":"Operator dependence of outcome after primary percutaneous coronary intervention","volume":"6","author":"Vlaar","year":"2011","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2024.07.016_bib17","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1093\/eurheartj\/ehv176","article-title":"Culprit lesion thrombus burden after manual thrombectomy or percutaneous coronary intervention-alone in ST-segment elevation myocardial infarction: the optical coherence tomography sub-study of the TOTAL (Thrombectomy Versus PCI Alone) trial","volume":"36","author":"Bhindi","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2024.07.016_bib18","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/j.jcin.2016.06.050","article-title":"Does residual thrombus after aspiration thrombectomy affect the outcome of primary PCI in patients with ST-segment elevation myocardial infarction? An optical coherence tomography study","volume":"9","author":"Higuma","year":"2016","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2024.07.016_bib19","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.jacc.2010.09.077","article-title":"Composition of coronary thrombus in acute myocardial infarction","volume":"57","author":"Silvain","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2024.07.016_bib20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ahj.2018.05.019","article-title":"Impact of total ischemic time on manual thrombus aspiration benefit during primary percutaneous coronary intervention","volume":"204","author":"Hugelshofer","year":"2018","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2024.07.016_bib21","first-page":"428","article-title":"Manual thrombus aspiration during primary percutaneous coronary intervention: impact of total ischemic time","volume":"69","author":"Sim","year":"2017","journal-title":"J\u00a0Cardiol"},{"key":"10.1016\/j.jcin.2024.07.016_bib22","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.3505","article-title":"Association of thrombus aspiration with time and mortality among patients with ST-segment elevation myocardial infarction: a post hoc analysis of the randomized TOTAL trial","volume":"4","author":"Moxham","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jcin.2024.07.016_bib23","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3349\/ymj.2014.55.3.606","article-title":"Efficacy of combination treatment with intracoronary abciximab and aspiration thrombectomy on myocardial perfusion in patients with ST-segment elevation myocardial infarction undergoing primary coronary stenting","volume":"55","author":"Ahn","year":"2014","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.jcin.2024.07.016_bib24","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1001\/jama.2012.421","article-title":"Intracoronary abciximab and aspiration thrombectomy in patients with large anterior myocardial infarction: the INFUSE-AMI randomized trial","volume":"307","author":"Stone","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jcin.2024.07.016_bib25","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/CIRCULATIONAHA.116.025371","article-title":"Thrombus aspiration in ST-segment-elevation myocardial infarction: an individual patient meta-analysis: Thrombectomy Trialists Collaboration","volume":"135","author":"Jolly","year":"2017","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jcin.2024.07.016_bib26","doi-asserted-by":"crossref","first-page":"e394","DOI":"10.4244\/EIJ-D-23-00112","article-title":"No-reflow after primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: an angiographic core laboratory analysis of the TOTAL trial","volume":"19","author":"d\u2019Entremont","year":"2023","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2024.07.016_bib27","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.122.012433","article-title":"Sustained mechanical aspiration thrombectomy for high thrombus burden coronary vessel occlusion: the multicenter CHEETAH study","volume":"16","author":"Mathews","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2024.07.016_bib28","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jcin.2022.09.050","article-title":"EnVast mechanical thrombectomy after thrombus aspiration failure in a STEMI with a massive thrombotic burden","volume":"16","author":"Bongiovanni","year":"2023","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2024.07.016_bib29","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4244\/EIJ-D-21-00741","article-title":"A\u00a0prospective, first-in-human use of the NeVa mechanical thrombectomy device for patients with acute coronary syndromes","volume":"18","author":"Spirito","year":"2022","journal-title":"EuroIntervention"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879824009804?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879824009804?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T19:40:20Z","timestamp":1760643620000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879824009804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":29,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S1936879824009804"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2024.07.016","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Failed Thrombus Aspiration and Reduced Myocardial Perfusion in Patients With STEMI and Large Thrombus Burden","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2024.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}