{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:57:55Z","timestamp":1790668675996,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jcin.2026.06.018","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:27:55Z","timestamp":1790623675000},"page":"2501-2511","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Performance and Reproducibility of the LIRA Method for TAVR in Bicuspid Anatomy"],"prefix":"10.1016","volume":"19","author":[{"given":"Barbara","family":"Bellini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Romano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianmarco","family":"Iannopollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Gorla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Moccetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"De Felice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5767-7416","authenticated-orcid":false,"given":"Andrea","family":"Buono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0895-440X","authenticated-orcid":false,"given":"Mauro","family":"Massussi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greca","family":"Zanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1565-9986","authenticated-orcid":false,"given":"Rene Hameau","family":"Davanzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celeste","family":"Manzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Cattaneo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4427-3404","authenticated-orcid":false,"given":"Gianluca","family":"Ricchetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciro","family":"Vella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Napoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca Angelo","family":"Ferri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7944-9756","authenticated-orcid":false,"given":"Marco Bruno","family":"Ancona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Adamo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Toggweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bedogni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eustachio","family":"Agricola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9732-9459","authenticated-orcid":false,"given":"Matteo","family":"Montorfano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2026.06.018_bib1","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1001\/jama.2021.13346","article-title":"Association between transcatheter aortic valve replacement for bicuspid vs tricuspid aortic stenosis and mortality or stroke among patients at low surgical risk","volume":"326","author":"Makkar","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.jcin.2026.06.018_bib2","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/j.jcin.2020.03.022","article-title":"Transcatheter aortic valve replacement in bicuspid versus tricuspid aortic valves from the STS\/ACC TVT registry","volume":"13","author":"Forrest","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.06.018_bib3","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1161\/CIRCULATIONAHA.119.040333","article-title":"Outcomes of transcatheter aortic valve replacement in patients with bicuspid aortic valve disease: a report from the Society of Thoracic Surgeons\/American College of Cardiology Transcatheter Valve Therapy Registry","volume":"141","author":"Halim","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2026.06.018_bib4","doi-asserted-by":"crossref","first-page":"3804","DOI":"10.1093\/eurheartj\/ehae331","article-title":"Transcatheter aortic valve implantation in low-risk tricuspid or bicuspid aortic stenosis: the NOTION-2 trial","volume":"45","author":"J\u00f8rgensen","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2026.06.018_bib5","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.007107","article-title":"Bicuspid aortic valve anatomy and relationship with devices: the BAVARD multicenter registry","volume":"12","author":"Tchetche","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.06.018_bib6","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.ijcard.2020.05.076","article-title":"Supra-annular sizing of transcatheter aortic valve prostheses in raphe-type bicuspid aortic valve disease: the LIRA method","volume":"317","author":"Iannopollo","year":"2020","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jcin.2026.06.018_bib7","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.jcct.2020.01.007","article-title":"Bicuspid aortic valve sizing for transcatheter aortic valve implantation: development and validation of an algorithm based on multislice computed tomography","volume":"14","author":"Petronio","year":"2020","journal-title":"J Cardiovasc Comput Tomogr"},{"issue":"Suppl","key":"10.1016\/j.jcin.2026.06.018_bib8","doi-asserted-by":"crossref","first-page":"S149","DOI":"10.1016\/j.carrev.2022.08.025","article-title":"Transcatheter aortic valve replacement for bicuspid aortic stenosis with a severely calcified raphe using an undersized SAPIEN 3 valve: sizing by the circle method and pressure-regulated deployment","volume":"53","author":"Tobe","year":"2023","journal-title":"Cardiovasc Revasc Med"},{"key":"10.1016\/j.jcin.2026.06.018_bib9","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/j.jcin.2025.05.043","article-title":"Redefining valve sizing for transcatheter aortic valve replacement using a validated multiplanar approach","volume":"18","author":"Yao","year":"2025","journal-title":"JACC Cardiovasc"},{"key":"10.1016\/j.jcin.2026.06.018_bib10","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.jcin.2019.02.051","article-title":"Understanding the interaction between transcatheter aortic valve prostheses and supra-annular structures from post-implant stent geometry","volume":"12","author":"Xiong","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.06.018_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.4244\/EIJ-D-19-00951","article-title":"A novel supra-annular plane to predict TAVI prosthesis anchoring in raphe-type bicuspid aortic valve disease: the LIRA plane","volume":"16","author":"Iannopollo","year":"2020","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2026.06.018_bib12","first-page":"831","article-title":"Supra-annular prosthesis anchoring in bicuspid aortic valve: evidence in large annuli exceeding the device sizing chart range","volume":"41","author":"Bellini","year":"2025","journal-title":"Can J Cardiol"},{"issue":"Suppl C","key":"10.1016\/j.jcin.2026.06.018_bib13","doi-asserted-by":"crossref","first-page":"C233","DOI":"10.1093\/eurheartj\/suac014","article-title":"Update on supra-annular sizing of transcatheter aortic valve prostheses in raphe-type bicuspid aortic valve disease according to the LIRA method","volume":"24","author":"Iannopollo","year":"2022","journal-title":"Eur Heart J Suppl"},{"key":"10.1016\/j.jcin.2026.06.018_bib14","first-page":"831","article-title":"Clinical outcomes of patients with bicuspid aortic valve undergoing a targeted transcatheter aortic valve replacement approach: the LIRA method","volume":"41","author":"Bellini","year":"2025","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.jcin.2026.06.018_bib15","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.jtcvs.2007.01.039","article-title":"A classification system for the bicuspid aortic valve from 304 surgical specimens","volume":"133","author":"Sievers","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jcin.2026.06.018_bib16","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1093\/eurheartj\/ehaa799","article-title":"Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research","volume":"42","author":"G\u00e9n\u00e9reux","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2026.06.018_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/ehjci\/jeaf195","article-title":"Stent frame deformation of self-expanding transcatheter heart valves in bicuspid aortic stenosis and impact on valve performance","volume":"26","author":"Tirado-Conte","year":"2025","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcin.2026.06.018_bib18","doi-asserted-by":"crossref","first-page":"502","DOI":"10.4244\/EIJ-D-23-00021","article-title":"Transcatheter aortic valve implantation with the Evolut platform for bicuspid aortic valve stenosis: the international, multicenter, prospective BIVOLUT-X registry","volume":"19","author":"Tch\u00e9tch\u00e9","year":"2023","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcin.2026.06.018_bib19","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1161\/CIRCULATIONAHA.124.069323","article-title":"Transcatheter aortic valve replacement with balloon-versus self-expanding bioprostheses for the treatment of bicuspid aortic valve stenosis","volume":"152","author":"Giacoppo","year":"2025","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2026.06.018_bib20","first-page":"press","article-title":"Balloon-expandable versus self-expanding valves for transcatheter treatment of Sievers type 1 bicuspid aortic stenosis","volume":"17in","author":"Buono","year":"2024","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.06.018_bib21","first-page":"146","article-title":"Incidence, predictors, and outcomes of subclinical valve thrombosis after transcatheter aortic valve replacement in bicuspid aortic valve stenosis","volume":"210","author":"Qiao","year":"2025","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2026.06.018_bib22","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.jcin.2025.03.028","article-title":"Long-term outcomes of patients requiring pacemaker implantation after transcatheter aortic valve replacement: the SwissTAVI registry","volume":"18","author":"Badertscher","year":"2025","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.06.018_bib23","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.amjcard.2023.10.018","article-title":"Impact of pacemaker implantation after transcatheter aortic valve replacement on long-term survival in patients with bicuspid aortic valve","volume":"210","author":"De Felice","year":"2025","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2026.06.018_bib24","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.amjcard.2025.09.042","article-title":"Predictors of permanent pacemaker implantation in patients with raphe-type bicuspid aortic valve stenosis undergoing TAVR","volume":"258","author":"Mangieri","year":"2025","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2026.06.018_bib25","first-page":"3265","article-title":"The NavigIIster: transcatheter aortic valve implantation with the Navitor platform in bicuspid anatomy","volume":"106","author":"Oliva","year":"2025","journal-title":"Catheter Cardiovasc Interv"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826019734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826019734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:28:01Z","timestamp":1790623681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879826019734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":25,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1936879826019734"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2026.06.018","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical Performance and Reproducibility of the LIRA Method for TAVR in Bicuspid Anatomy","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2026.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}