{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:49:49Z","timestamp":1791834589145,"version":"4.3.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jcin.2026.07.032","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:27:20Z","timestamp":1791833240000},"page":"2539-2551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Coronary Occlusions in NSTEMI Undergoing Percutaneous Coronary Intervention"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6990-4521","authenticated-orcid":false,"given":"Riyad Yazan","family":"Kherallah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Zaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazan","family":"Assaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel Chen","family":"Marks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4334-8133","authenticated-orcid":false,"given":"Neal S.","family":"Kleiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirza Umair","family":"Khalid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Mascarenhas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"Kayani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yochai","family":"Birnbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Wojdyla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh V.","family":"Swaminathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali A.","family":"Denktas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcin.2026.07.032_bib1","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/01.RES.87.10.837","article-title":"Molecular basis of electrocardiographic ST-segment elevation","volume":"87","author":"Li","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.jcin.2026.07.032_bib2","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.jacc.2008.12.014","volume":"53","author":"Rautaharju","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2026.07.032_bib3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(94)91161-4","volume":"343","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.jcin.2026.07.032_bib4","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1056\/NEJM198010163031601","article-title":"Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction","volume":"303","author":"DeWood","year":"1980","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2026.07.032_bib5","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.jacc.2024.11.009","article-title":"2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI guideline for the management of patients with acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"85","author":"Rao","year":"2025","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcin.2026.07.032_bib6","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1056\/NEJM199602223340801","article-title":"Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators","volume":"334","author":"Sgarbossa","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2026.07.032_bib7","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.022866","article-title":"Ischemic ST-segment depression maximal in V1-V4 (versus V5-V6) of any amplitude is specific for occlusion myocardial infarction (versus nonocclusive ischemia)","volume":"10","author":"Meyers","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jcin.2026.07.032_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2024.101314","article-title":"From ST-segment elevation MI to occlusion MI: the new paradigm shift in acute myocardial infarction","volume":"3","author":"McLaren","year":"2024","journal-title":"JACC Adv"},{"key":"10.1016\/j.jcin.2026.07.032_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2024.131889","article-title":"Systematic review and meta-analysis of diagnostic test accuracy of ST-segment elevation for acute coronary occlusion","volume":"402","author":"de Alencar Neto","year":"2024","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jcin.2026.07.032_bib10","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1093\/eurheartj\/ehx418","article-title":"Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis","volume":"38","author":"Khan","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2026.07.032_bib11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13054-018-1944-x","article-title":"Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded \u201cculprit\u201d artery - a systemic review and meta-analysis","volume":"22","author":"Hung","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.jcin.2026.07.032_bib12","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.amjcard.2014.11.023","article-title":"Incidence and impact of totally occluded culprit coronary arteries in patients presenting with non-ST-segment elevation myocardial infarction","volume":"115","author":"Warren","year":"2015","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcin.2026.07.032_bib13","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s12872-021-02099-y","article-title":"Impact of acute total occlusion of the culprit artery on outcome in NSTEMI based on the results of a large national registry","volume":"21","author":"Terlecki","year":"2021","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.jcin.2026.07.032_bib14","article-title":"Accuracy of OMI ECG findings versus STEMI criteria for diagnosis of acute coronary occlusion myocardial infarction","volume":"33","author":"Pendell Meyers","year":"2021","journal-title":"Int J Cardiol Heart Vasc"},{"key":"10.1016\/j.jcin.2026.07.032_bib15","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000268","article-title":"Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms","volume":"2","author":"McCabe","year":"2013","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jcin.2026.07.032_bib16","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ijcard.2019.07.043","article-title":"Prospective, real-world evidence showing the gap between ST elevation myocardial infarction (STEMI) and occlusion MI (OMI)","volume":"293","author":"Meyers","year":"2019","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jcin.2026.07.032_bib17","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1161\/01.CIR.56.5.786","article-title":"The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs","volume":"56","author":"Reimer","year":"1977","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2026.07.032_bib18","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.012429","article-title":"Time-dependent myocardial necrosis in patients with ST-segment-elevation myocardial infarction without angiographic collateral flow visualized by cardiac magnetic resonance imaging: results from the multicenter STEMI-SCAR project","volume":"8","author":"Greulich","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jcin.2026.07.032_bib19","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1161\/CIRCULATIONAHA.118.037152","article-title":"Early versus standard care invasive examination and treatment of patients with non-ST-segment elevation acute coronary syndrome","volume":"138","author":"Kofoed","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2026.07.032_bib20","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jcin.2015.11.018","article-title":"Immediate versus delayed invasive intervention for non-STEMI patients: the RIDDLE-NSTEMI study","volume":"9","author":"Milosevic","year":"2016","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.07.032_bib21","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jcin.2020.01.231","article-title":"Optimal timing of intervention in NSTE-ACS without pre-treatment: the EARLY randomized trial","volume":"13","author":"Lemesle","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.07.032_bib22","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1056\/NEJMoa0807986","article-title":"Early versus delayed invasive intervention in acute coronary syndromes","volume":"360","author":"Mehta","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcin.2026.07.032_bib23","first-page":"403","article-title":"Failure of standard contemporary ST-elevation myocardial infarction electrocardiogram criteria to reliably identify acute occlusion of the left anterior descending coronary artery","volume":"14","author":"Meyers","year":"2025","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.jcin.2026.07.032_bib24","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jcin.2025.10.018","article-title":"AI-enabled ECG analysis improves diagnostic accuracy and reduces false STEMI activations: a multicenter U.S. registry","volume":"19","author":"Herman","year":"2026","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcin.2026.07.032_bib25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/ehjdh\/ztad074","article-title":"International evaluation of an artificial intelligence-powered electrocardiogram model detecting acute coronary occlusion myocardial infarction","volume":"5","author":"Herman","year":"2024","journal-title":"Eur Heart J Digit Health"},{"key":"10.1016\/j.jcin.2026.07.032_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2026.102663","article-title":"AI-enhanced electrocardiogram for detection of occlusive myocardial infarction in high-risk non-ST-segment elevation acute coronary syndrome","volume":"5","author":"Carvalho","year":"2026","journal-title":"JACC Adv"},{"key":"10.1016\/j.jcin.2026.07.032_bib27","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1056\/NEJMoa066139","article-title":"Coronary intervention for persistent occlusion after myocardial infarction","volume":"355","author":"Hochman","year":"2006","journal-title":"N Engl J Med"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826023162?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826023162?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:27:56Z","timestamp":1791833276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879826023162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":27,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S1936879826023162"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2026.07.032","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute Coronary Occlusions in NSTEMI Undergoing Percutaneous Coronary Intervention","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2026.07.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 the American College of Cardiology Foundation. Published by Elsevier. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}