{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T08:10:46Z","timestamp":1791879046139,"version":"4.3.4"},"reference-count":37,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Interventions"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jcin.2026.08.007","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:27:20Z","timestamp":1791833240000},"page":"2571-2585","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Frequency and Prognosis of Alternative Definitions of Occlusion Myocardial Infarction Across the Whole Spectrum of Acute Coronary Syndromes"],"prefix":"10.1016","volume":"19","author":[{"given":"Andrea","family":"Milzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Zito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Landi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Frigoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5552-6382","authenticated-orcid":false,"given":"Giuseppe","family":"And\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Boccuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5150-188X","authenticated-orcid":false,"given":"Gianluca","family":"Campo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Frazzetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Covani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Maria","family":"De La Torre Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dik","family":"Heg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Sardella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnoud WJ.","family":"Vant\u2019Hof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinando","family":"Varbella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Vranckx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Valgimigli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"38","key":"10.1016\/j.jcin.2026.08.007_bib1","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.jcin.2026.08.007_bib3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1161\/CIRCULATIONAHA.121.055827","article-title":"Of occlusions, inclusions, and exclusions: time to reclassify infarctions?","volume":"144","author":"Sankardas","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jcin.2026.08.007_bib4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jelectrocard.2021.02.001","article-title":"STEMI: a transitional fossil in MI classification?","volume":"65","author":"Aslanger","year":"2021","journal-title":"J Electrocardiol"},{"issue":"11","key":"10.1016\/j.jcin.2026.08.007_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2024.101314","article-title":"From ST-Segment elevation MI to occlusion MI: the new paradigm shift in acute myocardial infarction","volume":"3","author":"McLaren","year":"2024","journal-title":"JACC Adv"},{"key":"10.1016\/j.jcin.2026.08.007_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2024.131980","article-title":"ST elevation is a poor surrogate for acute coronary occlusion. Let\u2019s replace STEMI with occlusion MI (OMI)","volume":"407","author":"Smith","year":"2024","journal-title":"Int J Cardiol"},{"issue":"41","key":"10.1016\/j.jcin.2026.08.007_bib7","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1093\/eurheartj\/ehx418","article-title":"Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis","volume":"38","author":"Khan","year":"2017","journal-title":"Eur Heart J"},{"issue":"supplement_2","key":"10.1016\/j.jcin.2026.08.007_bib8","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehad655.1536","article-title":"Poor prognosis of total culprit artery occlusion in patients presenting with NSTEMI","volume":"44","author":"Herman","year":"2023","journal-title":"Eur Heart J"},{"issue":"9986","key":"10.1016\/j.jcin.2026.08.007_bib9","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/S0140-6736(15)60292-6","article-title":"Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial","volume":"385","author":"Valgimigli","year":"2015","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.jcin.2026.08.007_bib10","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1056\/NEJMoa1507854","article-title":"Bivalirudin or unfractionated heparin in acute coronary syndromes","volume":"373","author":"Valgimigli","year":"2015","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.jcin.2026.08.007_bib11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/ehjdh\/ztad074","article-title":"International evaluation of an artificial intelligence\u2013powered electrocardiogram model detecting acute coronary occlusion myocardial infarction","volume":"5","author":"Herman","year":"2023","journal-title":"Eur Heart J Digit Health"},{"issue":"1","key":"10.1016\/j.jcin.2026.08.007_bib12","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/s12872-021-02099-y","article-title":"Impact of acute total occlusion of the culprit artery on outcome in NSTEMI based on the results of a large national registry","volume":"21","author":"Terlecki","year":"2021","journal-title":"BMC Cardiovasc Disord"},{"issue":"7","key":"10.1016\/j.jcin.2026.08.007_bib13","article-title":"Prevalence and predictors of occlusive myocardial infarction in patients presenting with Non-ST-Elevation acute coronary syndrome in duhok, Iraq: a cross-sectional study","volume":"16","author":"Mohammad","year":"2024","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.jcin.2026.08.007_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/eurheartj\/ehp376","article-title":"Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials","volume":"31","author":"Valgimigli","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcin.2026.08.007_bib15","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.amjcard.2021.06.043","article-title":"Totally occluded culprit coronary artery in patients with non-ST-elevation myocardial infarction undergoing percutaneous coronary intervention","volume":"156","author":"Fernando","year":"2021","journal-title":"Am J Cardiol"},{"issue":"4","key":"10.1016\/j.jcin.2026.08.007_bib16","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.hlc.2025.02.102","article-title":"National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: comprehensive Australian clinical guideline for diagnosing and managing acute coronary syndromes 2025","volume":"34","author":"Brieger","year":"2025","journal-title":"Heart Lung Circ"},{"key":"10.1016\/j.jcin.2026.08.007_bib17","article-title":"Impact of guidelines-directed very high-risk criteria in the identification and management of occlusion myocardial infarction in patients with NSTE-ACS","author":"Milzi","year":"2026","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.jcin.2026.08.007_bib18","article-title":"Accuracy of OMI ECG findings versus STEMI criteria for diagnosis of acute coronary occlusion myocardial infarction","volume":"33","author":"Pendell Meyers","year":"2021","journal-title":"Int J Cardiol Heart Vasc"},{"issue":"4","key":"10.1016\/j.jcin.2026.08.007_bib19","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.annemergmed.2024.11.019","article-title":"ECG patterns of occlusion myocardial infarction: a narrative review","volume":"85","author":"Ricci","year":"2025","journal-title":"Ann Emerg Med"},{"issue":"7","key":"10.1016\/j.jcin.2026.08.007_bib20","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1038\/s41591-023-02396-3","article-title":"Machine learning for ECG diagnosis and risk stratification of occlusion myocardial infarction","volume":"29","author":"Al-Zaiti","year":"2023","journal-title":"Nat Med"},{"issue":"3","key":"10.1016\/j.jcin.2026.08.007_bib21","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1536\/ihj.53.160","article-title":"Impact of total occlusion of an infarct-related artery on long-term mortality in acute non-ST-elevation myocardial infarction patients who underwent early percutaneous coronary intervention","volume":"53","author":"Kim","year":"2012","journal-title":"Int Heart J"},{"issue":"4","key":"10.1016\/j.jcin.2026.08.007_bib22","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.ahj.2009.01.004","article-title":"Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non-ST-elevation acute coronary syndromes undergoing diagnostic angiography","volume":"157","author":"Wang","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcin.2026.08.007_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6647626","article-title":"Acute occlusion of the infarct-related artery as a predictor of very long-term mortality in patients with acute myocardial infarction","volume":"2021","author":"Kos","year":"2021","journal-title":"Cardiol Res Pract"},{"issue":"5","key":"10.1016\/j.jcin.2026.08.007_bib24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00392-010-0269-9","article-title":"Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy","volume":"100","author":"Bahrmann","year":"2011","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jcin.2026.08.007_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2023.131569","article-title":"Comparison of diagnostic accuracy of current left bundle branch block and ventricular pacing ECG criteria for detection of occlusion myocardial infarction","volume":"395","author":"Lindow","year":"2024","journal-title":"Int J Cardiol"},{"issue":"1","key":"10.1016\/j.jcin.2026.08.007_bib26","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/joic.12078","article-title":"Impact of occluded culprit arteries on long-term clinical outcome in patients with non-ST-elevation myocardial infarction: 48-month follow-up results in the COREA-AMI registry","volume":"27","author":"Shin","year":"2014","journal-title":"J Interv Cardiol"},{"issue":"4","key":"10.1016\/j.jcin.2026.08.007_bib27","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.amjcard.2014.11.023","article-title":"Incidence and impact of totally occluded culprit coronary arteries in patients presenting with non-ST-segment elevation myocardial infarction","volume":"115","author":"Warren","year":"2015","journal-title":"Am J Cardiol"},{"issue":"11","key":"10.1016\/j.jcin.2026.08.007_bib28","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.3390\/medicina57111196","article-title":"Total occlusion of the infarct-related artery in Non-ST-Elevation myocardial infarction (NSTEMI)-how can we identify these patients?","volume":"57","author":"Morawska","year":"2021","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.jcin.2026.08.007_bib29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.amjcard.2022.11.013","article-title":"Clinical significance of culprit vessel occlusion in patients with non-ST-elevation myocardial infarction who underwent percutaneous coronary intervention","volume":"188","author":"Popovic","year":"2023","journal-title":"Am J Cardiol"},{"issue":"2","key":"10.1016\/j.jcin.2026.08.007_bib30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/clc.23755","article-title":"Using latent class analysis to identify clinical features of patients with occlusive myocardial infarction: preangiogram prediction remains difficult","volume":"45","author":"Knoery","year":"2022","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jcin.2026.08.007_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2025.1560369","article-title":"Identification of NSTE-ACS patients with totally occluded infarct-related artery: the role of the SAVE risk score in improved risk stratification","volume":"12","author":"Sun","year":"2025","journal-title":"Front Cardiovasc Med"},{"issue":"5","key":"10.1016\/j.jcin.2026.08.007_bib32","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1093\/ehjqcco\/qcae003","article-title":"Acute coronary occlusion with vs. without ST elevation: impact on procedural outcomes and long-term all-cause mortality","volume":"10","author":"Abusharekh","year":"2024","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"10.1016\/j.jcin.2026.08.007_bib33","author":"Riek"},{"issue":"17","key":"10.1016\/j.jcin.2026.08.007_bib34","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.3390\/jcm13175201","article-title":"OMI\/NOMI: time for a new classification of acute myocardial infarction","volume":"13","author":"Kola","year":"2024","journal-title":"J Clin Med"},{"issue":"2","key":"10.1016\/j.jcin.2026.08.007_bib35","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/ehjdh\/ztae002","article-title":"Detection of acute coronary occlusion with a novel mobile electrocardiogram device: a pilot study","volume":"5","author":"Zepeda-Echavarria","year":"2024","journal-title":"Eur Heart J Digit Health"},{"key":"10.1016\/j.jcin.2026.08.007_bib36","article-title":"DIagnostic accuracy oF electrocardiogram for acute coronary OCClUsion resuLTing in myocardial infarction (DIFOCCULT study)","volume":"30","author":"Aslanger","year":"2020","journal-title":"Int J Cardiol Heart Vasc"},{"key":"10.1016\/j.jcin.2026.08.007_bib37","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jelectrocard.2023.12.011","article-title":"Why do we keep missing left circumflex artery myocardial infarctions?","volume":"83","author":"Geffin","year":"2024","journal-title":"J Electrocardiol"},{"issue":"3","key":"10.1016\/j.jcin.2026.08.007_bib38","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1080\/10903127.2024.2399218","article-title":"Artificial intelligence driven prehospital ECG interpretation for the reduction of false positive emergent cardiac catheterization lab activations: a retrospective cohort study","volume":"29","author":"Baker","year":"2025","journal-title":"Prehosp Emerg Care"}],"container-title":["JACC: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826023174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936879826023174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:27:32Z","timestamp":1791833252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936879826023174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":37,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S1936879826023174"],"URL":"https:\/\/doi.org\/10.1016\/j.jcin.2026.08.007","relation":{},"ISSN":["1936-8798"],"issn-type":[{"value":"1936-8798","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequency and Prognosis of Alternative Definitions of Occlusion Myocardial Infarction Across the Whole Spectrum of Acute Coronary Syndromes","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Interventions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcin.2026.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}