{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:00:03Z","timestamp":1791554403366,"version":"4.3.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T00:00:00Z","timestamp":1599523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["canadianjournalofdiabetes.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Diabetes"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jcjd.2020.08.104","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T12:51:10Z","timestamp":1599051070000},"page":"236-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Conversations and Reactions Around Severe Hypoglycemia Study: Results of Hypoglycemia Experiences in Canadian Adults With Insulin-Treated Diabetes and Their Caregivers"],"prefix":"10.1016","volume":"45","author":[{"given":"Donna","family":"Mojdami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth D.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7590-7844","authenticated-orcid":false,"given":"Erik","family":"Spaepen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Syring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9mi","family":"Rabasa-Lhoret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubin","family":"Punthakee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Snoek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5417-9291","authenticated-orcid":false,"given":"Mark","family":"Peyrot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjd.2020.08.104_bib2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1152\/physrev.00045.2011","article-title":"Mechanisms of diabetic complications","volume":"93","author":"Forbes","year":"2013","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jcjd.2020.08.104_bib4","first-page":"1","article-title":"Assessment of the impact of fear of hypoglycemic episodes on glycemic and hypoglycemia management","volume":"29","author":"Leiter","year":"2005","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib5","doi-asserted-by":"crossref","first-page":"617","DOI":"10.2337\/diacare.10.5.617","article-title":"Fear of hypoglycemia: Quantification, validation, and utilization","volume":"10","author":"Cox","year":"1987","journal-title":"Diabetes Care"},{"issue":"Suppl","key":"10.1016\/j.jcjd.2020.08.104_bib6","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1016\/j.jcjd.2017.10.010","article-title":"Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada: Hypoglycemia","volume":"42","author":"Yale","year":"2018","journal-title":"Can J Diabetes"},{"issue":"Suppl","key":"10.1016\/j.jcjd.2020.08.104_bib7","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.jcjd.2016.08.033","article-title":"A\u00a0population-based study on incidence and associated risk factors for hypoglycemia in Canada: The InHYPO-DM Study","volume":"40","author":"Harris","year":"2016","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib8","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/pdi.138","article-title":"Glucagon administration---Underevaluated and undertaught","volume":"18","author":"Harris","year":"2001","journal-title":"Pract Diabetes Int"},{"key":"10.1016\/j.jcjd.2020.08.104_bib9","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1007\/s13300-019-00687-y","article-title":"Family members: The forgotten players in the diabetes care team (the TALK-HYPO Study)","volume":"10","author":"Ratzki-Leewing","year":"2019","journal-title":"Diabetes Ther"},{"key":"10.1016\/j.jcjd.2020.08.104_bib10","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jcjd.2013.09.001","article-title":"The effect of hypoglycemia on health-related quality of life: Canadian results from a multinational time trade-off survey","volume":"38","author":"Harris","year":"2014","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib11","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/dme.14067","article-title":"Impact of severe hypoglycaemia on psychological outcomes in adults with Type 2 diabetes: A systematic review","volume":"36","author":"Harris","year":"2019","journal-title":"Diabet Med"},{"key":"10.1016\/j.jcjd.2020.08.104_bib12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jcjd.2017.01.007","article-title":"The Canadian hypoglycemia assessment tool program: Insights into rates and implications of hypoglycemia from an observational study","volume":"42","author":"Aronson","year":"2018","journal-title":"Can J Diabetes"},{"issue":"Suppl","key":"10.1016\/j.jcjd.2020.08.104_bib13","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1016\/j.jcjd.2016.08.034","article-title":"Emergency medical services (EMS) assist-requiring hypoglycemia in diabetes patients","volume":"40","author":"Spaic","year":"2016","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib14","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jcjd.2014.04.001","article-title":"Acute management and outcomes of patients with diabetes mellitus presenting to Canadian emergency departments with hypoglycemia","volume":"39","author":"Rowe","year":"2015","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib15","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.jcjd.2018.01.010","article-title":"Direct health-care costs and productivity costs associated with hypoglycemia in adults with type 1 and type 2 diabetes mellitus that participated in the Canadian Hypoglycemia Assessment Tool Program","volume":"42","author":"O'Reilly","year":"2018","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.24095\/hpcdp.37.2.03","article-title":"The cost of diabetes in Canada over 10 years: Applying attributable health care costs to a diabetes incidence prediction model","volume":"37","author":"Bilandzic","year":"2017","journal-title":"Health Promot Chronic Dis Prev Can"},{"key":"10.1016\/j.jcjd.2020.08.104_bib17","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2017-000503","article-title":"Real-world crude incidence of hypoglycemia in adults with diabetes: Results of the InHypo-DM Study, Canada","volume":"6","author":"Ratzki-Leewing","year":"2018","journal-title":"BMJ Open Diabetes Res Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib18","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s13300-016-0157-z","article-title":"Hypoglycemia event rates: A comparison between real-world data and randomized controlled trial populations in insulin-treated diabetes","volume":"7","author":"Elliott","year":"2016","journal-title":"Diabetes Ther"},{"key":"10.1016\/j.jcjd.2020.08.104_bib19","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/dmrr.482","article-title":"Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: Influence of risk markers and selection","volume":"20","author":"Pedersen-Bjergaard","year":"2004","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.jcjd.2020.08.104_bib20","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.2337\/diacare.28.12.2948","article-title":"Hypoglycemia in type 2 diabetes: Pathophysiology, frequency, and effects of different treatment modalities","volume":"28","author":"Zammitt","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib21","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1464-5491.1993.tb00051.x","article-title":"Frequency and morbidity of severe hypoglycemia in insulin-treated diabetic patients","volume":"10","author":"MacLeod","year":"1993","journal-title":"Diabet Med"},{"key":"10.1016\/j.jcjd.2020.08.104_bib22","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/dom.12689","article-title":"Rates and predictors of hypoglycaemia in 27 585 people from 24 countries with insulin-treated type 1 and type 2 diabetes: The global HAT study","volume":"18","author":"Khunti","year":"2016","journal-title":"Diabetes Obesity Metab"},{"key":"10.1016\/j.jcjd.2020.08.104_bib23","doi-asserted-by":"crossref","first-page":"697","DOI":"10.2337\/diacare.17.7.697","article-title":"Frequency of severe hypoglycemia in patients with type 1 diabetes with impaired awareness of hypoglycemia","volume":"17","author":"Gold","year":"1994","journal-title":"Diabetes Care"},{"issue":"Suppl","key":"10.1016\/j.jcjd.2020.08.104_bib24","first-page":"S52","article-title":"The \u201cunspoken\u201d truth: Suboptimal reporting of severe hypoglycemia in diabetes (InHypo-DM Study)","volume":"42","author":"Ratzki-Leewing","year":"2018","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib25","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jcjd.2018.08.201","article-title":"Insulin-treated diabetes and driving: Legal jeopardy and consequences of hypoglycemia","volume":"43","author":"Blumer","year":"2019","journal-title":"Can J Diabetes"},{"issue":"Suppl","key":"10.1016\/j.jcjd.2020.08.104_bib26","first-page":"S150","article-title":"Diabetes Canada 2018 Clinical practice guidelines for the prevention and management of diabetes in Canada: Diabetes and driving","volume":"42","author":"Ratzki-Leewing","year":"2018","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2020.08.104_bib27","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-005625","article-title":"'I'm not a druggie, I'm just a diabetic': A qualitative study of stigma from the perspective of adults with type 1 diabetes","volume":"4","author":"Browne","year":"2014","journal-title":"BMJ Open"},{"key":"10.1016\/j.jcjd.2020.08.104_bib28","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/dme.14205","article-title":"How has psycho-behavioural research advanced our understanding of hypoglycaemia in type 1 diabetes?","volume":"37","author":"Hendrieckx","year":"2020","journal-title":"Diabet Med"},{"issue":"22","key":"10.1016\/j.jcjd.2020.08.104_bib29","article-title":"Blood glucose awareness training and epinephrine responses to hypoglycemia during intensive treatment in type 1 diabetes","volume":"22","author":"Kinsley","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib30","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s10865-005-9026-3","article-title":"Randomized controlled clinical trial of Blood Glucose Awareness Training (BGAT III) in Switzerland and Germany","volume":"28","author":"Schachinger","year":"2005","journal-title":"J\u00a0Behav Med"},{"key":"10.1016\/j.jcjd.2020.08.104_bib31","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.2337\/dc15-0102","article-title":"interventions that restore awareness of hypoglycemia in adults with type 1 diabetes: A systematic review and meta-analysis","volume":"38","author":"Yeoh","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib32","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.2337\/dc14-0030","article-title":"Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2\u00a0\u00d7 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS)","volume":"37","author":"Little","year":"2014","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib33","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1007\/s00125-005-1905-1","article-title":"Glycaemic control and severe hypoglycaemia following training in flexible, intensive insulin therapy to enable dietary freedom in people with type 1 diabetes: A prospective implementation study","volume":"48","author":"Samann","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.jcjd.2020.08.104_bib34","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.2337\/dc11-1579","article-title":"Improved biomedical and psychological outcomes 1 year after structured education in flexible insulin therapy for people with type 1 diabetes: The U.K. DAFNE experience","volume":"35","author":"Hopkins","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2020.08.104_bib35","unstructured":"BAQSIMI Canada Product Monograph. Eli Lilly Canada Inc: Toronto, 2019."}],"updated-by":[{"DOI":"10.1016\/j.jcjd.2021.02.004","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000}}],"container-title":["Canadian Journal of Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1499267120303488?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1499267120303488?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T15:33:28Z","timestamp":1696606408000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1499267120303488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S1499267120303488"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjd.2020.08.104","relation":{},"ISSN":["1499-2671"],"issn-type":[{"value":"1499-2671","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Conversations and Reactions Around Severe Hypoglycemia Study: Results of Hypoglycemia Experiences in Canadian Adults With Insulin-Treated Diabetes and Their Caregivers","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Diabetes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjd.2020.08.104","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published on behalf of the Canadian Diabetes Association.","name":"copyright","label":"Copyright"}]}}