{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:06:57Z","timestamp":1792091217946,"version":"4.4.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["canadianjournalofdiabetes.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Diabetes"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.jcjd.2022.08.004","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T08:46:52Z","timestamp":1661244412000},"page":"73-77","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A Comprehensive Therapeutic Patient Education May Improve Wound Healing and Reduce Ulcer Recurrence and Mortality in Persons With Type 2 Diabetes"],"prefix":"10.1016","volume":"47","author":[{"given":"Adriana","family":"Coppola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Montalcini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Gallotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8518-5547","authenticated-orcid":false,"given":"Anna","family":"Ferrulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Pujia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Luzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9974-0735","authenticated-orcid":false,"given":"Carmine","family":"Gazzaruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjd.2022.08.004_bib1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s12020-020-02431-0","article-title":"Predictors of healing, ulcer recurrence and persistence, amputation and mortality in type 2 diabetic patients with diabetic foot: A ten-year retrospective cohort study","volume":"71","author":"Gazzaruso","year":"2021","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib2","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1056\/NEJMra1615439","article-title":"Diabetic foot ulcers and their recurrence","volume":"376","author":"Armstrong","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcjd.2022.08.004_bib3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.2337\/dc17-1836","article-title":"Current challenges and opportunities in the prevention and management of diabetic foot ulcers","volume":"41","author":"Jeffcoate","year":"2018","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2022.08.004_bib4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s12020-015-0775-7","article-title":"The role of patient education in the prevention and management of type 2 diabetes: An overview","volume":"53","author":"Coppola","year":"2016","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib5","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/dme.13340","article-title":"Effectiveness of group-based self-management education for individuals with Type 2 diabetes: A systematic review with meta-analyses and meta-regression","volume":"34","author":"Odgers-Jewell","year":"2017","journal-title":"Diabet Med"},{"key":"10.1016\/j.jcjd.2022.08.004_bib6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s12020-016-0947-0","article-title":"Structured therapeutic education in diabetes: Is it time to re-write the chapter on the prevention of diabetic complications?","volume":"53","author":"Gazzaruso","year":"2016","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib7","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S2213-8587(17)30239-5","article-title":"Diabetes structured self-management education programmes: A narrative review and current innovations","volume":"6","author":"Chatterjee","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.jcjd.2022.08.004_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.3105","article-title":"Motivational interviewing to improve adherence behaviours for the prevention of diabetic foot ulceration","volume":"35","author":"Binning","year":"2019","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.jcjd.2022.08.004_bib9","first-page":"CD001488","article-title":"Patient education for preventing diabetic foot ulceration","volume":"2014","author":"Dorresteijn","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jcjd.2022.08.004_bib10","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.2337\/diacare.28.5.1019","article-title":"Amputation prevention initiative in South India: Positive impact of foot care education","volume":"28","author":"Viswanathan","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2022.08.004_bib11","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1007\/s00125-008-1110-0","article-title":"Education for secondary prevention of foot ulcers in people with diabetes: A randomised controlled trial","volume":"51","author":"Lincoln","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.jcjd.2022.08.004_bib12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.foot.2017.12.004","article-title":"Risk factors for diabetic foot ulcer recurrence: A prospective 2-year follow-up study in Egypt","volume":"35","author":"Khalifa","year":"2018","journal-title":"Foot (Edinb)"},{"key":"10.1016\/j.jcjd.2022.08.004_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2018.e00614","article-title":"A\u00a0systematic review and meta-analysis of patient education in preventing and reducing the incidence or recurrence of adult diabetes foot ulcers (DFU)","volume":"4","author":"Adiewere","year":"2018","journal-title":"Heliyon"},{"key":"10.1016\/j.jcjd.2022.08.004_bib14","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1089\/dia.2014.0004","article-title":"Effect of intensive nursing education on the prevention of diabetic foot ulceration among patients with high-risk diabetic foot: A follow-up analysis","volume":"16","author":"Ren","year":"2014","journal-title":"Diabetes Technol Ther"},{"key":"10.1016\/j.jcjd.2022.08.004_bib15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2020-001657","article-title":"Service user and community clinician design of a partially virtual diabetic service improves access to care and education and reduces amputation incidence","volume":"9","author":"Watt","year":"2021","journal-title":"BMJ Open Diabetes Res Care"},{"key":"10.1016\/j.jcjd.2022.08.004_bib16","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1177\/1534734620934578","article-title":"Impact of diabetes foot care education on amputation rate in the University of Abuja Teaching Hospital, Nigeria","volume":"21","author":"Anumah","year":"2020","journal-title":"Int J Low Extrem Wounds"},{"key":"10.1016\/j.jcjd.2022.08.004_bib17","doi-asserted-by":"crossref","first-page":"923","DOI":"10.2147\/VHRM.S13569","article-title":"Impact of a diabetic foot care education program on lower limb amputation rate","volume":"6","author":"Al-Wahbi","year":"2010","journal-title":"Vasc Health Risk Manag"},{"issue":"Suppl. 1","key":"10.1016\/j.jcjd.2022.08.004_bib18","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/dmrr.2237","article-title":"Patient education for preventing diabetic foot ulceration","volume":"28","author":"Dorresteijn","year":"2012","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.jcjd.2022.08.004_bib19","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s12020-017-1427-x","article-title":"Role of structured individual patient education in the prevention of vascular complications in newly diagnosed type 2 diabetes: the INdividual Therapeutic Education in Newly Diagnosed type 2 diabetes (INTEND) randomized controlled trial","volume":"60","author":"Coppola","year":"2018","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s11739-011-0527-5","article-title":"Screening for asymptomatic coronary artery disease can reduce cardiovascular mortality in type 2 diabetic patients","volume":"7","author":"Gazzaruso","year":"2012","journal-title":"Intern Emerg Med"},{"key":"10.1016\/j.jcjd.2022.08.004_bib21","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s12020-011-9544-4","article-title":"Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus","volume":"41","author":"Gazzaruso","year":"2012","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib22","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1016\/j.jacc.2007.10.069","article-title":"Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with asymptomatic coronary artery disease angiographically proven. A potential protective role for statins and 5-phosphodiesterase inhibitors","volume":"51","author":"Gazzaruso","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcjd.2022.08.004_bib23","first-page":"1","article-title":"Silent coronary artery disease in type 2 diabetes mellitus: The role of Lipoprotein(a), homocysteine and apo(a) polymorphism","volume":"22","author":"Gazzaruso","year":"2002","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.jcjd.2022.08.004_bib24","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.2337\/dc12-1401","article-title":"Transcutaneous oxygen tension as a potential predictor of cardiovascular events in type 2 diabetes: Comparison with ankle-brachial index","volume":"36","author":"Gazzaruso","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jcjd.2022.08.004_bib25","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.amjcard.2005.07.133","article-title":"Association of the metabolic syndrome and insulin resistance with silent myocardial ischemia in patients with type 2 diabetes mellitus","volume":"97","author":"Gazzaruso","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcjd.2022.08.004_bib26","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifugate","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin Chem"},{"key":"10.1016\/j.jcjd.2022.08.004_bib27","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000180580","article-title":"Prediction of creatinine clearance from serum creatinine","volume":"16","author":"Cockcroft","year":"1976","journal-title":"Nephron"},{"key":"10.1016\/j.jcjd.2022.08.004_bib28","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1161\/01.CIR.0000133278.81226.C9","article-title":"Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients","volume":"110","author":"Gazzaruso","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jcjd.2022.08.004_bib29","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s12020-018-1714-1","article-title":"People with diabetes do not learn and recall their diabetes foot education: A cohort study","volume":"62","author":"Yuncken","year":"2018","journal-title":"Endocrine"},{"key":"10.1016\/j.jcjd.2022.08.004_bib30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jcjd.2021.04.011","article-title":"Patient, support-person and health-care provider perspectives on foot self-management for adults with type 1 and type 2 diabetes: Personal challenges","volume":"46","author":"Stevens","year":"2022","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2022.08.004_bib31","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jcjd.2020.09.004","article-title":"Outcomes of diabetic foot ulcers in a tertiary referral interdisciplinary clinic: A retrospective Canadian study","volume":"45","author":"Fournier","year":"2021","journal-title":"Can J Diabetes"},{"key":"10.1016\/j.jcjd.2022.08.004_bib32","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1111\/dme.14326","article-title":"Effectiveness of psychosocial interventions for the prevention and treatment of foot ulcers in people with diabetes: A systematic review","volume":"37","author":"Norman","year":"2020","journal-title":"Diabet Med"}],"container-title":["Canadian Journal of Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1499267122002441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1499267122002441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:38:50Z","timestamp":1761493130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1499267122002441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S1499267122002441"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjd.2022.08.004","relation":{},"ISSN":["1499-2671"],"issn-type":[{"value":"1499-2671","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Comprehensive Therapeutic Patient Education May Improve Wound Healing and Reduce Ulcer Recurrence and Mortality in Persons With Type 2 Diabetes","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Diabetes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjd.2022.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Canadian Diabetes Association.","name":"copyright","label":"Copyright"}]}}