{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:48:52Z","timestamp":1768589332136,"version":"3.49.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","canadianjournalofophthalmology.ca","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.jcjo.2024.04.011","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T05:50:16Z","timestamp":1716875416000},"page":"e515-e524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Wolfram-silicone implants as effective radiation shielding for ocular brachytherapy: dosimetric features and in vivo animal study on biocompatibility"],"prefix":"10.1016","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8675-7001","authenticated-orcid":false,"given":"Ekaterina A.","family":"Sokolenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0736-8946","authenticated-orcid":false,"given":"Dirk","family":"Fl\u00fchs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0068-2934","authenticated-orcid":false,"given":"Fotis","family":"Lalos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miltiadis","family":"Fiorentzis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9811-2849","authenticated-orcid":false,"given":"Migle","family":"Lindziute","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justine","family":"Gemmecke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Utta","family":"Berchner-Pfannschmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Hendgen-Cotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos E.","family":"Bechrakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodora","family":"Tsimpaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Dubicanac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Wi\u00dfmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gero","family":"Hilken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjo.2024.04.011_bib0001","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41572-020-0158-0","article-title":"Uveal melanoma","volume":"6","author":"Jager","year":"2020","journal-title":"Nat Rev Dis Primer"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0002","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.31557\/APJCP.2022.23.5.1791","article-title":"Global incidence and trend of uveal melanoma from 1943\u20132015: a meta-analysis","volume":"23","author":"Naseripoor","year":"2022","journal-title":"Asian Pac J Cancer Prev"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0003","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1016\/j.ophtha.2007.01.032","article-title":"Incidence of uveal melanoma in Europe","volume":"114","author":"Virgili","year":"2007","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0004","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1001\/jamaophthalmol.2019.2546","article-title":"Survival of young patients with posterior uveal melanoma","volume":"137","author":"Al-Jamal","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0005","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1001\/archopht.119.5.670","article-title":"Assessment of metastatic disease status at death in 435 patients with large choroidal melanoma in the Collaborative Ocular Melanoma Study (COMS): COMS report no. 15","volume":"119","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0006","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1001\/archopht.123.12.1639","article-title":"Development of metastatic disease after enrollment in the COMS trials for treatment of choroidal melanoma: Collaborative Ocular Melanoma Study Group report no. 26","volume":"123","author":"Diener-West","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0007","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/eye.2016.275","article-title":"Uveal melanoma: relatively rare but deadly cancer","volume":"31","author":"Kaliki","year":"2017","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0008","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1097\/ICU.0000000000000761","article-title":"Radiation therapy for uveal melanoma: a review of treatment methods available in 2021","volume":"32","author":"Reichstein","year":"2021","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0009","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.ajo.2003.12.032","article-title":"Survival, anatomic, and functional long-term results in choroidal and ciliary body melanoma after ruthenium brachytherapy (15 years\u2019 experience with beta-rays)","volume":"137","author":"Rouberol","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0010","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/S0161-6420(02)01273-3","article-title":"Iodine 125 plaque brachytherapy versus transscleral tumor resection in the treatment of large uveal melanomas","volume":"109","author":"Bechrakis","year":"2002","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0011","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/PL00007880","article-title":"Long-term follow-up of Ru-106\/Rh-106 brachytherapy for posterior uveal melanoma","volume":"238","author":"Lommatzsch","year":"2000","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0012","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000455872","article-title":"Iodine-125 brachytherapy for uveal melanoma: a systematic review of radiation dose","volume":"3","author":"Echegaray","year":"2017","journal-title":"Ocul Oncol Pathol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0013","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1167\/iovs.04-0066","article-title":"Effect of radiation dose on ocular complications after iodine brachytherapy for large uveal melanoma: empirical data and simulation of collimating plaques","volume":"45","author":"Puusaari","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0014","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1002\/mp.13341","article-title":"A comparison of the shielding effectiveness of silicone oil vitreous substitutes when used with palladium-103 and iodine-125 eye plaques","volume":"46","author":"Yang","year":"2019","journal-title":"Med Phys"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0015","first-page":"e5270","article-title":"Silicone oil and iodine-125 brachytherapy for uveal melanoma in high-risk patients","volume":"11","author":"Lyons","year":"2019","journal-title":"Cureus"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0016","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ijrobp.2014.02.021","article-title":"Iodine 125 brachytherapy with vitrectomy and silicone oil in the treatment of uveal melanoma: 1-to-1 matched case-control series","volume":"89","author":"McCannel","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0017","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1007\/s00417-016-3485-9","article-title":"23-mm iodine-125 plaque for uveal melanoma: benefit of vitrectomy and silicone oil on visual acuity","volume":"254","author":"McCannel","year":"2016","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0018","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/eye.2012.158","article-title":"The effects of intraocular silicone oil placement prior to iodine 125 brachytherapy for uveal melanoma: a clinical case series","volume":"26","author":"Ahuja","year":"2012","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0019","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/archophthalmol.2010.117","article-title":"Attenuation of iodine 125 radiation with vitreous substitutes in the treatment of uveal melanoma","volume":"128","author":"Oliver","year":"2010","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0020","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.brachy.2019.05.013","article-title":"Delivered dose changes in COMS plaque-based ocular brachytherapy arising from vitrectomy with silicone oil replacement","volume":"18","author":"Morrison","year":"2019","journal-title":"Brachytherapy"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0021","series-title":"Medical Physics","first-page":"E240","article-title":"GafChromic film dosimetry for evaluation of intraocular shielding materials in I-125 eye plaque brachytherapy","author":"Oare","year":"2022"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0022","series-title":"Medical Physics","first-page":"E241","article-title":"Dose distribution with a high-Z intraocular shield-ferrofluid system: an I-125 eye plaque brachytherapy Monte Carlo study\u202c","author":"Oare","year":"2022"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0023","doi-asserted-by":"crossref","DOI":"10.1071\/PH610443","article-title":"Gamma-radiation absorption coefficients of various materials allowing for bremsstrahlung and other secondary radiations","volume":"14","author":"Allison","year":"1961","journal-title":"Aust J Phys"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0024","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/jbm.820090610","article-title":"Reaction associated with a silicone rubber gel: an experimental study","volume":"9","author":"Rigdon","year":"1975","journal-title":"J Biomed Mater Res"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0025","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1177\/088532828800300405","article-title":"RTV silicone adhesives for medical devices","volume":"3","author":"Winn","year":"1989","journal-title":"J Biomater Appl"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0026","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3109\/10408444.2014.1003422","article-title":"An update to the toxicological profile for water-soluble and sparingly soluble tungsten substances","volume":"45","author":"Lemus","year":"2015","journal-title":"Crit Rev Toxicol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0027","series-title":"Scintillation Dosimetry","article-title":"2D and 3D scintillation dosimetry for brachytherapy","author":"Fl\u00fchs","year":"2016"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0028","series-title":"Entwicklung eines Binuklidapplikators f\u00fcr die Brachytherapie von Augentumoren und Untersuchungen zur Dosimetrie von Augenapplikatoren (in German)","author":"Ebenau","year":"2017"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0029","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1118\/1.597736","article-title":"Direct reading measurement of absorbed dose with plastic scintillators: the general concept and applications to ophthalmic plaque dosimetry","volume":"23","author":"Fl\u00fchs","year":"1996","journal-title":"Med Phys"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1159\/000381720","article-title":"Polyethylene naphthalate scintillator: a novel detector for the dosimetry of radioactive ophthalmic applicators","volume":"2","author":"Fl\u00fchs","year":"2015","journal-title":"Ocul Oncol Pathol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0031","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000477409","article-title":"Inhomogeneous surface dose distributions of 106Ru eye plaques","volume":"4","author":"Eichmann","year":"2017","journal-title":"Ocul Oncol Pathol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0032","doi-asserted-by":"crossref","first-page":"4634","DOI":"10.1118\/1.3218762","article-title":"Development of a high precision dosimetry system for the measurement of surface dose rate distribution for eye applicators","volume":"36","author":"Eichmann","year":"2009","journal-title":"Med Phys"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0033","doi-asserted-by":"crossref","first-page":"N421","DOI":"10.1088\/0031-9155\/57\/22\/N421","article-title":"Development of a high-precision xyz-measuring table for the determination of the 3D dose rate distributions of brachytherapy sources","volume":"57","author":"Eichmann","year":"2012","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0034","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1159\/000479558","article-title":"Dose distributions and treatment margins in ocular brachytherapy with 106Ru eye plaques","volume":"4","author":"St\u00f6ckel","year":"2018","journal-title":"Ocul Oncol Pathol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0035","unstructured":"Pa\u00df C. Messtechnische Untersuchung zum Absorptionsverhalten von Wolfram-Silikon-Gemischen bei niederenergetischer Photonenstrahlung im Bulbus unter Augenapplikator-Brachytherapie (Master's thesis, Westf\u00e4lische Hochschule Gelsenkirchen, 2020) (in German)."},{"key":"10.1016\/j.jcjo.2024.04.011_bib0036","unstructured":"Marlog N. Numerische Simulation zum Absorptionsverhalten von Metall-Silikon-Gemischen im Bulbus in der Augenapplikator-Brachytherapie (Master's thesis, Westf\u00e4lische Hochschule Gelsenkirchen, 2020)(in German)."},{"key":"10.1016\/j.jcjo.2024.04.011_bib0037","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0002-9394(14)77826-2","article-title":"Experimental epiretinal membranes induced by intravitreal carbon particles","volume":"96","author":"Algvere","year":"1983","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.04.011_bib0038","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1001\/archopht.1995.01100030115033","article-title":"Epiretinal membrane formation: light and electron microscopic study in an experimental rabbit model","volume":"113","author":"Kono","year":"1995","journal-title":"Arch Ophthalmol"}],"container-title":["Canadian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418224001248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418224001248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T17:51:24Z","timestamp":1726595484000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008418224001248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S0008418224001248"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjo.2024.04.011","relation":{},"ISSN":["0008-4182"],"issn-type":[{"value":"0008-4182","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Wolfram-silicone implants as effective radiation shielding for ocular brachytherapy: dosimetric features and in vivo animal study on biocompatibility","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjo.2024.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of Canadian Ophthalmological Society.","name":"copyright","label":"Copyright"}]}}