{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:22:16Z","timestamp":1757571736307,"version":"3.40.5"},"reference-count":31,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"am","delay-in-days":354,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","canadianjournalofophthalmology.ca","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.jcjo.2024.05.015","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T20:19:18Z","timestamp":1718828358000},"page":"e73-e82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Stratified choroidal vascular structure in treatment-na\u00efve diabetic retinopathy"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3782-6748","authenticated-orcid":false,"given":"Hiroaki","family":"Endo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3426-1674","authenticated-orcid":false,"given":"Satoru","family":"Kase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shozo","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Sakoguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiji","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Katsuta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Kase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjo.2024.05.015_bib0001","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1016\/j.ophtha.2018.04.007","article-title":"Guidelines on diabetic eye care: The International Council of Ophthalmology Recommendations for Screening, Follow-up, Referral, and Treatment Based on Resource Settings","volume":"125","author":"Wong","year":"2018","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0002","doi-asserted-by":"crossref","first-page":"364","DOI":"10.4093\/dmj.2018.0182","article-title":"Pathophysiology of diabetic retinopathy: the old and the new","volume":"42","author":"Kusuhara","year":"2018","journal-title":"Diabetes Metab J"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0003","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.survophthal.2018.03.003","article-title":"Assessment of flow dynamics in retinal and choroidal microcirculation","volume":"63","author":"Wei","year":"2018","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0004","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.visres.2017.04.003","article-title":"The pathology associated with diabetic retinopathy","volume":"139","author":"Lechner","year":"2017","journal-title":"Vision Res"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0005","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0161-6420(85)34013-7","article-title":"Diabetic choroidopathy. Light and electron microscopic observations of seven cases","volume":"92","author":"Hidayat","year":"1985","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0006","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.visres.2017.04.011","article-title":"Diabetic choroidopathy","volume":"139","author":"Lutty","year":"2017","journal-title":"Vision Res"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0007","doi-asserted-by":"crossref","first-page":"158","DOI":"10.5301\/ejo.5000676","article-title":"Choroidal thickness in diabetic retinopathy in relation to long-term systemic treatments for diabetes mellitus","volume":"26","author":"Kase","year":"2016","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0008","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1111\/ceo.13299","article-title":"Alteration of layer thickness in the choroid of diabetic patients","volume":"46","author":"Endo","year":"2018","journal-title":"Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0009","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00417-019-04295-1","article-title":"Relationship between choroidal structure and duration of diabetes","volume":"257","author":"Endo","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0010","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/bjophthalmol-2019-314273","article-title":"Alteration of choroidal vascular structure in diabetic retinopathy","volume":"104","author":"Kase","year":"2020","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0011","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ajo.2020.05.036","article-title":"Choroidal thickness in diabetic patients without diabetic retinopathy: a meta-analysis","volume":"218","author":"Endo","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0012","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1007\/s00417-021-05292-z","article-title":"Choroidal vascular structures in diabetic patients: a meta-analysis","volume":"259","author":"Kase","year":"2021","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0013","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s10384-018-0631-4","article-title":"Kago-Eye2 software for semi-automated segmentation of subfoveal choroid of optical coherence tomographic images","volume":"63","author":"Sonoda","year":"2019","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0014","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/S0161-6420(03)00475-5","article-title":"Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales","volume":"110","author":"Wilkinson","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0015","first-page":"3799","article-title":"High-resolution histologic analysis of the human choroidal vasculature","volume":"35","author":"McLeod","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0016","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/aos.13210","article-title":"Viewing the choroid: where we stand, challenges and contradictions in diabetic retinopathy and diabetic macular oedema","volume":"95","author":"Campos","year":"2017","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0017","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","article-title":"The multifunctional choroid","volume":"29","author":"Nickla","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0018","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1167\/iovs.61.3.50","article-title":"Microvascular changes in the choriocapillaris of diabetic patients without retinopathy investigated by swept-source oct angiography","volume":"61","author":"Dai","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0019","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40942-020-00209-0","article-title":"Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept-source optical coherence tomography angiography","volume":"6","author":"Gendelman","year":"2020","journal-title":"Int J Retina Vitreous"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0020","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1001\/archopht.116.5.589","article-title":"Choriocapillaris degeneration and related pathologic changes in human diabetic eyes","volume":"116","author":"Cao","year":"1998","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0021","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1136\/bjo.2003.035345","article-title":"Alteration of choroidal circulation in the foveal region in patients with type 2 diabetes","volume":"88","author":"Nagaoka","year":"2004","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0022","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1023\/B:INTE.0000031744.93778.60","article-title":"Foveolar choroidal hemodynamics in proliferative diabetic retinopathy","volume":"25","author":"Schocket","year":"2004","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0023","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1755-3768.1989.tb07080.x","article-title":"Blood flow in the human eye","volume":"191","author":"Langham","year":"1989","journal-title":"Acta Ophthalmol Suppl"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0024","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1600-0420.1997.tb00626.x","article-title":"Pulsatile ocular blood flow in untreated diabetic retinopathy","volume":"75","author":"MacKinnon","year":"1997","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0025","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1034\/j.1600-0420.1999.770507.x","article-title":"Pulsatile ocular blood flow in diabetic retinopathy","volume":"77","author":"Geyer","year":"1999","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0026","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1038\/s41598-023-29216-5","article-title":"Qualitative and quantitative evaluation of diabetic choroidopathy using ultra-widefield indocyanine green angiography","volume":"13","author":"Choi","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0027","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1056\/NEJM199412013312203","article-title":"Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders","volume":"331","author":"Aiello","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0028","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1167\/iovs.18-26381","article-title":"New insights on choroidal vascularity: a comprehensive topographic approach","volume":"60","author":"Goud","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0029","doi-asserted-by":"crossref","first-page":"132","DOI":"10.21873\/invivo.12684","article-title":"Downregulation of alphaB-crystallin in retinal pigment epithelial cells exposed to diabetes-related stimuli in vivo and in vitro","volume":"36","author":"Wu","year":"2022","journal-title":"In Vivo"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0030","doi-asserted-by":"crossref","first-page":"7510","DOI":"10.1167\/iovs.12-10311","article-title":"Automated segmentation of the choroid from clinical SD-OCT","volume":"53","author":"Zhang","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jcjo.2024.05.015_bib0031","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1364\/BOE.385113","article-title":"Automated morphometric measurement of the retinal pigment epithelium complex and choriocapillaris using swept source OCT","volume":"6","author":"Zhou","year":"2020","journal-title":"Biomed Opt Express"}],"container-title":["Canadian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418224001583?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418224001583?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T16:00:31Z","timestamp":1747238431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008418224001583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0008418224001583"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjo.2024.05.015","relation":{},"ISSN":["0008-4182"],"issn-type":[{"type":"print","value":"0008-4182"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stratified choroidal vascular structure in treatment-na\u00efve diabetic retinopathy","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjo.2024.05.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}