{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T22:42:54Z","timestamp":1764628974617,"version":"3.46.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100012424","name":"University of California San Diego School of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012424","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["canadianjournalofophthalmology.ca","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jcjo.2025.04.011","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T22:08:03Z","timestamp":1749161283000},"page":"e800-e806","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of neurotrophic keratopathy on quality of life: a utility analysis"],"prefix":"10.1016","volume":"60","author":[{"given":"Suzan","family":"Sargsyan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7917-5633","authenticated-orcid":false,"given":"Sammie E.","family":"Fung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9245-244X","authenticated-orcid":false,"given":"Tonya S.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn S.","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2558-5733","authenticated-orcid":false,"given":"Brian M.","family":"Fung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6239-1965","authenticated-orcid":false,"given":"Erik","family":"Groessl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Ozzello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby S.","family":"Korn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don O.","family":"Kikkawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie A.","family":"Afshari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine Y.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjo.2025.04.011_bib0001","series-title":"CME Monograph","article-title":"An evidence-based approach to the diagnosis and treatment of neurotrophic keratopathy","author":"Akpek","year":"2019"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0002","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1097\/ICO.0000000000002974","article-title":"Edge: Topical Recombinant Nerve Growth Factor for the Treatment of Neurotrophic Keratopathy-Biologicals as a Novel Therapy for Neurotrophic Keratopathy","volume":"41","author":"Hamrah","year":"2022","journal-title":"Cornea"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0003","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.exer.2013.08.011","article-title":"The role of corneal afferent neurons in regulating tears under normal and dry eye conditions","volume":"117","author":"Meng","year":"2013","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0004","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2147\/EB.S117261","article-title":"Neurotrophic keratitis: current challenges and future prospects","volume":"10","author":"Versura","year":"2018","journal-title":"Eye Brain"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jtos.2021.02.010","article-title":"Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes","volume":"20","author":"Liu","year":"2021","journal-title":"Ocul Surf"},{"year":"2003","series-title":"Making choices in health: WHO guide to cost-effectiveness analysis","key":"10.1016\/j.jcjo.2025.04.011_bib0006"},{"year":"1996","series-title":"Applications of utility theory in the economic evaluation of health care. [Toepassingen van Nutstheorie in de Economische Evaluatie van Gezondheidszorg]","author":"Bleichrodt","key":"10.1016\/j.jcjo.2025.04.011_bib0007"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0008","first-page":"645","article-title":"Technology growth and expenditure growth in health care","volume":"50","author":"Chandra","year":"2012","journal-title":"Natl Bur Econ Res Bull Aging Health"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0009","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1001\/jama.1989.03430200123038","article-title":"Clinical economics: A guide to the economic analysis of clinical practices","volume":"262","author":"Eisenberg","year":"1989","journal-title":"JAMA"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0010","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/PRS.0b013e3181904d3a","article-title":"Corneal neurotization: a novel solution to neurotrophic keratopathy","volume":"123","author":"Terzis","year":"2009","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0011","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1016\/j.ophtha.2013.04.030","article-title":"Cataract surgery cost utility revisited in 2012: a new economic paradigm","volume":"120","author":"Brown","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0012","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/01.ijg.0000185434.08051.82","article-title":"Utility values in Singapore Chinese adults with primary open-angle and primary angle-closure glaucoma","volume":"14","author":"Saw","year":"2005","journal-title":"J Glaucoma"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0013","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0002-9394(99)00146-4","article-title":"Utility values and diabetic retinopathy","volume":"128","author":"Brown","year":"1999","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0014","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1001\/archopht.118.1.47","article-title":"Utility values and age-related macular degeneration","volume":"118","author":"Brown","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0015","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s11136-012-0270-z","article-title":"Measuring the impact of cataract surgery on generic and vision-specific quality of life","volume":"22","author":"Groessl","year":"2013","journal-title":"Qual Life Res"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0016","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jclinepi.2010.04.010","article-title":"Five preference-based indexes in cataract and heart failure patients were not equally responsive to change","volume":"64","author":"Kaplan","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0017","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1056\/NEJMp1612619","article-title":"Cost-effectiveness analysis 2.0","volume":"376","author":"Neumann","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0018","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.ophtha.2007.06.008","article-title":"The impact of anchor point on utilities for 5 common ophthalmic diseases","volume":"115","author":"Lee","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0019","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1037\/0278-6133.1.1.61","article-title":"Health-related quality of life measurement for evaluation research and policy analysis","volume":"1","author":"Kaplan","year":"1982","journal-title":"Health Psychol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0020","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.jclinepi.2004.03.012","article-title":"New ICD-10 version of the Charlson comorbidity index predicted in-hospital mortality","volume":"57","author":"Sundararajan","year":"2004","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0021","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/archopht.119.7.1050","article-title":"Development of the 25-item National Eye Institute Visual Function Questionnaire","volume":"119","author":"Mangione","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0022","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/S0161-6420(03)00462-7","article-title":"Utility assessment among patients with dry eye disease","volume":"110","author":"Schiffman","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0023","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/lary.28216","article-title":"The health utility of mild and severe dysphonia","volume":"130","author":"DeVore","year":"2020","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0024","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jhsa.2014.08.048","article-title":"The utility of hand transplantation in hand amputee patients","volume":"40","author":"Alolabi","year":"2015","journal-title":"J Hand Surg Am"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0025","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1017\/S0266462300008461","article-title":"Utilities and quality-adjusted life years","volume":"5","author":"Torrance","year":"1989","journal-title":"Int J Technol Assess Health Care"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0026","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s41687-020-00192-y","article-title":"Development of the neurotrophic keratopathy questionnaire: qualitative research","volume":"4","author":"Murray","year":"2020","journal-title":"J Patient Rep Outcomes"},{"author":"Graham","key":"10.1016\/j.jcjo.2025.04.011_bib0027"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0028","first-page":"473","article-title":"Vision and quality-of-life","volume":"97","author":"Brown","year":"1999","journal-title":"Trans Am Ophthalmol Soc"},{"year":"1996","series-title":"Cost-effectiveness in health and medicine","author":"Gold","key":"10.1016\/j.jcjo.2025.04.011_bib0029"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0030","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1177\/0272989X9501500212","article-title":"Explaining distortions in utility elicitation through the rank-dependent model for risky choices","volume":"15","author":"Wakker","year":"1995","journal-title":"Med Decis Making"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0031","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.3111\/13696998.2013.839946","article-title":"A systematic literature review of utility weights in wet age-related macular degeneration","volume":"16","author":"Pearson","year":"2013","journal-title":"J Med Econ"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0032","first-page":"118","article-title":"A utility maximization model for evaluation of health care programs","volume":"7","author":"Torrance","year":"1972","journal-title":"Health Serv Res"},{"key":"10.1016\/j.jcjo.2025.04.011_bib0033","unstructured":"Neurotrophic keratitis. OXERVATETM (cenegermin-bkbj). https:\/\/oxervate-approved.com\/. Accessed August 5, 2025."},{"key":"10.1016\/j.jcjo.2025.04.011_bib0034","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/IOP.0000000000001583","article-title":"Corneal neurotization: a review of pathophysiology and outcomes","volume":"36","author":"Park","year":"2020","journal-title":"Ophthalmic Plast Reconstr Surg"}],"container-title":["Canadian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418225001589?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418225001589?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T22:40:43Z","timestamp":1764628843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008418225001589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0008418225001589"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjo.2025.04.011","relation":{},"ISSN":["0008-4182"],"issn-type":[{"type":"print","value":"0008-4182"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of neurotrophic keratopathy on quality of life: a utility analysis","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjo.2025.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}