{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T13:13:09Z","timestamp":1784207589468,"version":"3.55.0"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["canadianjournalofophthalmology.ca","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jcjo.2026.06.004","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:18:31Z","timestamp":1784204311000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of eyelid colobomas associated with FREM1-related disorder (Manitoba oculotrichoanal syndrome)"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2276-6464","authenticated-orcid":false,"given":"Michael T.","family":"Kryshtalskyj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4921-5830","authenticated-orcid":false,"given":"Antonio","family":"Florido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5290-5130","authenticated-orcid":false,"given":"Carson D.","family":"Schell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin D.","family":"Hyrcza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4861-7651","authenticated-orcid":false,"given":"Peter J.","family":"Dolman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0348-5069","authenticated-orcid":false,"given":"Lisa","family":"Lagrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3098-1172","authenticated-orcid":false,"given":"Hyunjae N.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4980-9982","authenticated-orcid":false,"given":"Karim G.","family":"Punja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcjo.2026.06.004_bib0001","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s12887-021-02506-5","article-title":"Facial cleft? The first case of Manitoba-oculo-tricho-anal syndrome with novel mutations in China: a case report","volume":"21","author":"Gu","year":"2021","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.jcjo.2026.06.004_bib0002","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/ajmg.a.31446","article-title":"Manitoba oculotrichoanal (MOTA) syndrome: report of eight new cases","volume":"143A","author":"Li","year":"2007","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.jcjo.2026.06.004_bib0003","first-page":"325","article-title":"Clinical and histological features and outcomes of upper eyelid colobomas in the Saudi population","volume":"39","author":"Al Essa","year":"2020","journal-title":"Orbit Amst Neth"},{"key":"10.1016\/j.jcjo.2026.06.004_bib0004","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ophtha.2012.07.079","article-title":"Internal cantholysis for repair of moderate and large full-thickness eyelid defects","volume":"120","author":"Perry","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jcjo.2026.06.004_bib0005","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.1177\/11206721221085400","article-title":"Pillar tarsoconjunctival flap: an alternative approach for the management of refractory corneal ulcer","volume":"32","author":"Zamorano-Martin","year":"2022","journal-title":"Eur J Ophthalmol"}],"container-title":["Canadian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418226002231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008418226002231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:18:32Z","timestamp":1784204312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008418226002231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":5,"alternative-id":["S0008418226002231"],"URL":"https:\/\/doi.org\/10.1016\/j.jcjo.2026.06.004","relation":{},"ISSN":["0008-4182"],"issn-type":[{"value":"0008-4182","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of eyelid colobomas associated with FREM1-related disorder (Manitoba oculotrichoanal syndrome)","name":"articletitle","label":"Article Title"},{"value":"Canadian Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcjo.2026.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}