{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:42:00Z","timestamp":1789926120853,"version":"4.0.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Anesthesia"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.jclinane.2011.02.003","type":"journal-article","created":{"date-parts":[[2011,7,9]],"date-time":"2011-07-09T06:04:20Z","timestamp":1310191460000},"page":"418-426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Perioperative management of von Willebrand disease: a review for the anesthesiologist"],"prefix":"10.1016","volume":"23","author":[{"given":"Michael A.","family":"Mazzeffi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc E.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jclinane.2011.02.003_bb0005","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1182\/blood.V69.2.454.454","article-title":"Epidemiological investigation of the prevalence of von Willebrand's disease","volume":"69","author":"Rodeghiero","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0010","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/(SICI)1096-8652(199812)59:4<288::AID-AJH4>3.0.CO;2-I","article-title":"Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators","volume":"59","author":"Soucie","year":"1998","journal-title":"Am J Hematol"},{"issue":"4706","key":"10.1016\/j.jclinane.2011.02.003_bb0015","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1126\/science.3874428","article-title":"Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization","volume":"228","author":"Ginsburg","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0020","first-page":"224","article-title":"Biosynthesis of human von Willebrand factor","volume":"18","author":"Verweij","year":"1998","journal-title":"Haemostasis"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0025","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1073\/pnas.71.5.1906","article-title":"Synthesis of von Willebrand factor by cultured human endothelial cells","volume":"71","author":"Jaffe","year":"1974","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0030","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1172\/JCI108846","article-title":"Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes","volume":"60","author":"Nachman","year":"1977","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0035","first-page":"637","article-title":"Binding of human von Willebrand factor to collagen and to collagen-stimulated platelets","volume":"109","author":"Pietu","year":"1987","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0040","doi-asserted-by":"crossref","first-page":"21948","DOI":"10.1016\/S0021-9258(18)54729-3","article-title":"The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII","volume":"266","author":"Wise","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0045","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1056\/NEJMra040403","article-title":"Treatment of von Willebrand's Disease","volume":"351","author":"Mannucci","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0050","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1172\/JCI115123","article-title":"The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain","volume":"87","author":"Cooney","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0055","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0950-3536(98)80051-6","article-title":"Aquired von Willebrand disease","volume":"11","author":"van Genderen","year":"1998","journal-title":"Baillieres Clin Haematol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0060","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1056\/NEJMoa022831","article-title":"Acquired von Willebrand syndrome in aortic stenosis","volume":"349","author":"Vincentelli","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0065","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1001\/archinte.1995.00430130095010","article-title":"Usefulness of patient interview in bleeding disorders","volume":"155","author":"Sr\u00e1mek","year":"1995","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0070","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1111\/j.1538-7836.2005.01663.x","article-title":"The discriminant power of bleeding history for diagnosis of type I von Willebrand disease: an international, multi-center study","volume":"3","author":"Rodeghiero","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0075","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1111\/j.1538-7836.2008.03182.x","article-title":"Generation and validation of the Condensed MCMDM-1VWD Bleeding Questionnaire for von Willebrand disease","volume":"6","author":"Bowman","year":"2008","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0080","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s005990050046","article-title":"Laboratory diagnosis of von Willebrand disease","volume":"28","author":"Veyradier","year":"1998","journal-title":"Int J Clin Lab Res"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0085","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1055\/s-0037-1614626","article-title":"Evaluation of the PFA-100 system in the diagnosis and therapeutic monitoring of patients with von Willebrand disease","volume":"82","author":"Cattaneo","year":"1999","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0090","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1182\/blood.V91.4.1325","article-title":"Screening for von Willebrand Disease with a new analyzer using high shear stress: a study of 60 cases","volume":"91","author":"Fressinaud","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0095","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/(SICI)1096-8652(199911)62:3<165::AID-AJH6>3.0.CO;2-C","article-title":"Use of a novel platelet function analyzer (PFA-100) with high sensitivity to disturbances in von Willebrand factor to screen for von Willebrand's disease and other disorders","volume":"62","author":"Favaloro","year":"1999","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0100","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/00001721-200206000-00011","article-title":"Rational Use of the PFA-100 device for screening of platelet function disorders and von Willebrand disease","volume":"13","author":"Buyukasik","year":"2002","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0105","series-title":"The diagnosis, evaluation and management of von Willebrand Disease. Clinical practice guidelines: Hemophilia and von Willebrand's disease","year":"2007"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0110","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1055\/s-2006-947863","article-title":"Laboratory tests for measurement of von Willebrand's factor show poor agreement among different centers: results from the United Kingdom National External Quality Assessment Scheme for Blood Coagulation","volume":"32","author":"Kitchen","year":"2006","journal-title":"Semin Thromb Hemost"},{"issue":"8017","key":"10.1016\/j.jclinane.2011.02.003_bb0115","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(77)91197-7","article-title":"Capitanio A. 1-Deamino-8-D-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands' diseases","volume":"1","author":"Mannucci","year":"1977","journal-title":"Lancet"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0120","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1172\/JCI9516","article-title":"Vasopressin induced von Willebrand's factor secretion from endothelial cells involves V2 receptors and cAMP","volume":"106","author":"Kaufmann","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0125","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1056\/NEJM198804073181403","article-title":"Hemodynamic and coagulation responses to 1-desamino[8-D-arginine] vasopressin in patients with congenital nephrogenic diabetes insipidus","volume":"318","author":"Bichet","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0130","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1182\/blood-2003-06-2072","article-title":"Biologic response to desmopressin in patients with severe type I and type II von Willebrand disease: results of a multicenter European study","volume":"103","author":"Federici","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0135","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1182\/blood-2007-08-109231","article-title":"Response to desmopressin is influenced by the genotype and phenotype in Type I von Willebrand disease (VWD): results from the European study MCMDM-1VWD","volume":"111","author":"Castaman","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0140","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1365-2141.1992.tb04598.x","article-title":"Patterns of development of tachyphylaxis in patients with haemophilia and von Willebrand disease after repeated doses of desmopressin (DDAVP)","volume":"82","author":"Mannuci","year":"1992","journal-title":"Br J Haemotol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0145","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0049-3848(88)90316-7","article-title":"Clinical Evaluation of subcutaneously administered DDAVP","volume":"49","author":"Ghirardini","year":"1988","journal-title":"Thromb Res"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0150","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2257.1984.tb00548.x","article-title":"Evaluation of the effectiveness of DDAVP in surgery and in bleeding episodes in haemophilia and von Willebrand's disease. A study on 43 patients","volume":"6","author":"Mariana","year":"1984","journal-title":"Clin Lab Haematol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0155","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0030-4220(06)80099-X","article-title":"Evaluation of desmopressin for dental extractions in patients with hemostatic disorders","volume":"77","author":"Saulnier","year":"1994","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0160","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1365-2516.2000.00370.x","article-title":"Optimising local therapy during surgery in patients with von Willebrand disease: effective results from a retrospective analysis of 63 cases","volume":"6","author":"Federici","year":"2000","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0165","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1046\/j.1365-2516.2001.00500.x","article-title":"High-dose DDAVP intranasal spray (Stimate) for the prevention and treatment of bleeding in patients with mild haemophilia A, mild or moderate type I von Willebrand disease and symptomatic carriers of haemophilia A","volume":"7","author":"Leissinger","year":"2001","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0170","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1002\/ajh.1058","article-title":"Retrospective review of the management of elective surgery with desmopressin and clotting factor concentrates in patients with von Willebrand's disease","volume":"66","author":"Nitu-Whalley","year":"2001","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0175","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1046\/j.1365-2516.2002.00589.x","article-title":"Efficacy of desmopressin as surgical prophylaxis in patients with acquired von Willebrand disease undergoing thyroid surgery","volume":"8","author":"Franchini","year":"2002","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0180","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jpeds.2009.01.051","article-title":"Incidence of bleeding complications in pediatric patients with type I von Willebrand disease undergoing adenotonsillar procedures","volume":"155","author":"Witmer","year":"2009","journal-title":"J Pediatr"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0185","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/ajh.2830310310","article-title":"Hyponatremia and seizures in young children given DDAVP","volume":"31","author":"Smith","year":"1989","journal-title":"Am J Haematol"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0190","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1056\/NEJM198801143180215","article-title":"Myocardial infarction in a patient with hemophilia treated with DDAVP","volume":"318","author":"Bond","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0195","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/ajh.2830280115","article-title":"Thrombosis following desmopressin for uremic bleeding","volume":"28","author":"Byrnes","year":"1988","journal-title":"Am J Hematol"},{"issue":"Suppl 2","key":"10.1016\/j.jclinane.2011.02.003_bb0200","first-page":"s33","article-title":"Surgical prophylaxis in von Willebrand's disease: a difficult balance to manage","volume":"6","author":"Franchini","year":"2008","journal-title":"Blood Transfus"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0205","first-page":"117","article-title":"Evidence-based recommendations on the treatment of von Willebrand disease in Italy","volume":"7","author":"Mannucci","year":"2009","journal-title":"Blood Transfus"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0210","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1111\/j.1538-7836.2007.02588.x","article-title":"von Willebrand factor\/factor VIII concentrate (Haemate P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery","volume":"5","author":"Lethagen","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0215","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1182\/blood.V99.2.450","article-title":"Treatment of von Willebrand disease with a high purity factor VIII\/von Willebrand factor concentrate: a prospective multicenter study","volume":"99","author":"Mannucci","year":"2002","journal-title":"Blood"},{"issue":"Suppl 1","key":"10.1016\/j.jclinane.2011.02.003_bb0220","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1097\/01.mbc.0000167658.85143.49","article-title":"Management of von Willebrand disease with factor VIII\/von Willebrand factor concentrates: results from current studies and surveys","volume":"16","author":"Federici","year":"2005","journal-title":"Blood Coagul Fibrinolysis"},{"issue":"Suppl 3","key":"10.1016\/j.jclinane.2011.02.003_bb0225","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1365-2516.1998.0040s3033.x","article-title":"Pharmakokinetics, efficacy and safety of Humate-P in von Willebrand disease","volume":"4","author":"Dobrkovska","year":"1998","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0230","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/s-0037-1612977","article-title":"Association of Hemophilia Clinic Directors of Canada. Efficacy and safety of the factor VIII\/von Willebrand factor concentrate, haemate-P\/humate-P: ristocetin cofactor unit dosing in patients with von Willebrand disease","volume":"87","author":"Lillicrap","year":"2002","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0235","first-page":"1279","article-title":"Efficacy and safety of factor VIII\/von Willebrand's factor concentrate (Haemate-P) in preventing bleeding during surgery or invasive procedures in patients with von Willebrand disease","volume":"88","author":"Franchini","year":"2003","journal-title":"Haematologica"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0240","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/00001721-200406000-00006","article-title":"Bleeding prophylaxis for major surgery in patients with type 2 won Willebrand disease with an intermediate purity factor VIII-Von Willebrand factor concentrate (Haemate-P)","volume":"15","author":"Michiels","year":"2004","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0245","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1046\/j.1351-8216.2003.00809.x","article-title":"Successful treatment for patients with von Willebrand disease undergoing urgent surgery using factor VIII\/VWF concentrate (Humate-P)","volume":"10","author":"Thompson","year":"2004","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0250","doi-asserted-by":"crossref","first-page":"944","DOI":"10.3324\/haematol.11124","article-title":"Clinical use of Haemate P in inherited von Willebrand's disease: a cohort study on 100 Italian patients","volume":"92","author":"Federici","year":"2007","journal-title":"Haematologica"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0255","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2516.2007.01616.x","article-title":"Efficacy of factor VIII\/von Willebrand factor concentrate Alphanate in preventing excessive bleeding during surgery in subjects with von Willebrand disease","volume":"14","author":"Rivard","year":"2008","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0260","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1365-2516.2009.02088.x","article-title":"Efficacy and safety of highly purified, doubly virus-inactivated VWF\/VIII concentrates in inherited von Willebrand's disease: results of an Italian cohort study on 120 patients characterized by bleeding severity score","volume":"16","author":"Federici","year":"2010","journal-title":"Haemophilia"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0265","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1600-0609.1984.tb02777.x","article-title":"Non Factor VIII related constituents in concentrates","volume":"41","author":"Allain","year":"1984","journal-title":"Scand J Haematol Suppl"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0270","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1182\/blood.V30.3.375.375","article-title":"Correction of the hemostatic defects in von Willebrand's disease","volume":"30","author":"Perkins","year":"1967","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0275","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1056\/NEJM199807233390407","article-title":"Hemostatic Drugs","volume":"339","author":"Mannucci","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0280","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1182\/blood.V77.9.1901.1901","article-title":"Hemostatic effect of normal platelet transfusion in severe von Willebrand disease patients","volume":"77","author":"Castillo","year":"1991","journal-title":"Blood"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0285","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1537-2995.1987.27387235627.x","article-title":"The efficacy of intensive plasma exchange in acquired von Willebrand's disease","volume":"27","author":"Silberstein","year":"1987","journal-title":"Transfusion"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0290","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1136\/pgmj.70.830.916","article-title":"High-dose intravenous gammaglobulin therapy for acquired von Willebrand disease","volume":"70","author":"Van Genderen","year":"1994","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.jclinane.2011.02.003_bb0295","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1177\/107602969900500302","article-title":"Acquired von Willebrand disease in monoclonal gammapathies: effectiveness of high-dose intravenous gamma globulin","volume":"5","author":"Michiels","year":"1999","journal-title":"Clin Appl Thromb Hemost"}],"container-title":["Journal of Clinical Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818011002121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818011002121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T08:59:34Z","timestamp":1760605174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952818011002121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S0952818011002121"],"URL":"https:\/\/doi.org\/10.1016\/j.jclinane.2011.02.003","relation":{},"ISSN":["0952-8180"],"issn-type":[{"value":"0952-8180","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perioperative management of von Willebrand disease: a review for the anesthesiologist","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jclinane.2011.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}