{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:05:14Z","timestamp":1793156714183,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100013738","name":"Pacira Pharmaceuticals","doi-asserted-by":"crossref","award":["402-C-405"],"award-info":[{"award-number":["402-C-405"]}],"id":[{"id":"10.13039\/100013738","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100013738","name":"Pacira Pharmaceuticals","doi-asserted-by":"crossref","award":["MSE402"],"award-info":[{"award-number":["MSE402"]}],"id":[{"id":"10.13039\/100013738","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Anesthesia"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.jclinane.2018.04.013","type":"journal-article","created":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T19:31:10Z","timestamp":1525375870000},"page":"41-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Thoracic paravertebral block versus thoracic epidural analgesia for post-operative pain control in open pancreatic surgery: A randomized controlled trial"],"prefix":"10.1016","volume":"48","author":[{"given":"Jacob L.","family":"Hutchins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Grandelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Kaizer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric H.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jclinane.2018.04.013_bb0005","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1016\/S0140-6736(06)68700-X","article-title":"Persistent postsurgical pain: risk factors and prevention","volume":"367","author":"Kehlet","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0010","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/00000658-200110000-00015","article-title":"Effect of epidural anesthesia and analgesia on perioperative outcome: a randomized, controlled Veterans Affairs cooperative study","volume":"234","author":"Park","year":"2001","journal-title":"Ann Surg"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0015","doi-asserted-by":"crossref","first-page":"887","DOI":"10.2147\/JPR.S122918","article-title":"Thoracic epidural analgesia reduces myocardial injury ischemic patients undergoing major abdominal cancer surgery","volume":"10","author":"Mohamad","year":"2017","journal-title":"J Pain Res"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0020","article-title":"Epidural local anesthetics versus opioid-based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery","volume":"7","author":"Guay","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0025","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1007\/s11605-014-2604-3","article-title":"High performing whipple patients: factors associated with short length of stay after open pancreaticoduodenectomy","volume":"18","author":"Lee","year":"2014","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0030","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1007\/s00268-014-2653-5","article-title":"Enhanced recovery after surgery pathway in patients undergoing pancreaticoduodenectomy","volume":"38","author":"Braga","year":"2014","journal-title":"The World Journal of Surgery"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0035","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.amjsurg.2012.05.022","article-title":"Effect of epidural analgesia on postoperative complications following pancreaticoduodenectomy","volume":"204","author":"Amini","year":"2012","journal-title":"The American Journal of Surgery"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0040","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/S0140-6736(02)08266-1","article-title":"Epidural anesthesia and analgesia and outcome of major surgery: a randomized trial","volume":"359","author":"Rigg","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0045","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/jhbp.307","article-title":"Epidural anesthesia dysfunction is associated with postoperative complications after pancreatectomy","volume":"23","author":"Sugimoto","year":"2016","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0050","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/jso.23815","article-title":"Peri-operative epidural may not be the preferred form of analgesia in select patients undergoing pancreaticoduodenectomy","volume":"111","author":"Axelrod","year":"2015","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0055","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1097\/MPA.0b013e3181bdfc76","article-title":"For patients undergoing pancreatoduodenectomy, epidural anesthesia and analgesia improves pain but increases rates of intensive care unit admissions and alterations in analgesics","volume":"39","author":"Choi","year":"2010","journal-title":"Pancreas"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0060","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1007\/s11605-008-0467-1","article-title":"Epidural analgesia for pancreatoduodenectomy: a critical appraisal","volume":"12","author":"Pratt","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0065","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/MPA.0000000000000031","article-title":"Poor analgesic efficacy of epidural analgesia in critical care patients after pancreaticoduodenectomy","volume":"42","author":"Patel","year":"2014","journal-title":"Pancreas"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0070","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1093\/bja\/aeq378","article-title":"Bilateral thoracic paravertebral block: potential and practice","volume":"106","author":"Richardson","year":"2011","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0075","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.ijsu.2014.07.272","article-title":"Paravertebral block for video-assisted thoracoscopic surgery: analgesic effectiveness and role in fast track surgery","volume":"12","author":"Komatsu","year":"2014","journal-title":"Int J Surg"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0080","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s11748-012-0149-5","article-title":"Safety of the paravertebral block in patients ineligible for epidural block under-going pulmonary resection","volume":"60","author":"Katayama","year":"2012","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0085","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s00540-014-1947-y","article-title":"Ultrasound-guided continuous thoracic paravertebral block provides comparable analgesia and fewer episodes of hypotension than continuous epidural block after lung surgery","volume":"29","author":"Okajima","year":"2015","journal-title":"J Anesth"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0090","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/AAP.0b013e3182176f42","article-title":"Comparison of continuous thoracic epidural with paravertebral block on perioperative analgesia and hemodynamic stability in patients having open lung surgery","volume":"36","author":"Pintaric","year":"2011","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0095","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/pan.13104","article-title":"Comparison of caudal ropivacaine-morphine and paravertebral catheter for major upper abdominal surgery in infants","volume":"27","author":"Sato","year":"2017","journal-title":"Pediatric Anesthesia"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0100","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/AAP.0000000000000422","article-title":"Epidural versus paravertebral nerve block for postoperative analgesia in patients undergoing open liver resection: a randomized clinical trial","volume":"41","author":"Schreiber","year":"2016","journal-title":"Regional Anesthesia and Acute Pain"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0105","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/AAP.0b013e3181c75a8b","article-title":"In-plane ultrasound-guided thoracic paravertebral block: a preliminary report of 36 cases with confirmation of catheter position","volume":"35","author":"Renes","year":"2010","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0110","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1213\/00000539-197011000-00020","article-title":"A postanesthetic recovery score","volume":"49","author":"Aldrete","year":"1970","journal-title":"Anesth Anal"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0120","series-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2017"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0125","first-page":"1","article-title":"Paravertebral block versus thoracic epidural for patients undergoing thoracotomy (review)","volume":"2","author":"Yeung","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0130","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1213\/01.ane.0000333274.63501.ff","article-title":"A systematic review of randomized trials evaluating regional techniques for post-thoracotomy analgesia","volume":"107","author":"Joshi","year":"2008","journal-title":"Anesth Anal"},{"key":"10.1016\/j.jclinane.2018.04.013_bb0135","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1093\/bja\/ael020","article-title":"A comparison of the analgesic efficacy and side effects of paravertebral vs. epidural blockade for thoracotomy\u2014a systematic review and meta-analysis of randomized trial","volume":"96","author":"Davies","year":"2006","journal-title":"Br J Anaesth"}],"container-title":["Journal of Clinical Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818018302848?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818018302848?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:11:20Z","timestamp":1760605880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952818018302848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":26,"alternative-id":["S0952818018302848"],"URL":"https:\/\/doi.org\/10.1016\/j.jclinane.2018.04.013","relation":{},"ISSN":["0952-8180"],"issn-type":[{"value":"0952-8180","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thoracic paravertebral block versus thoracic epidural analgesia for post-operative pain control in open pancreatic surgery: A randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jclinane.2018.04.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}