{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:17:31Z","timestamp":1784290651011,"version":"3.55.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["\/ NCATS 1UL1TR001425"],"award-info":[{"award-number":["\/ NCATS 1UL1TR001425"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Anesthesia"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.jclinane.2020.110027","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:44:05Z","timestamp":1600994645000},"page":"110027","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Sugammadex versus neostigmine for routine reversal of rocuronium block in adult patients: A cost analysis"],"prefix":"10.1016","volume":"67","author":[{"given":"William E.","family":"Hurford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Welge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H.","family":"Eckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jclinane.2020.110027_bb0005","first-page":"112","volume":"58","year":"2016","journal-title":"Med Lett Drugs Ther"},{"key":"10.1016\/j.jclinane.2020.110027_bb0010","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.jval.2013.02.002","article-title":"Consolidated health economic evaluation reporting standards (CHEERS)\u2014explanation and elaboration: a report of the ISPOR health economic evaluation publication guidelines good reporting practices task force","volume":"16","author":"Husereau","year":"2013","journal-title":"Value Health"},{"key":"10.1016\/j.jclinane.2020.110027_bb0015","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2147\/CEOR.S100921","article-title":"Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center","volume":"8","author":"Carron","year":"2016","journal-title":"Clinicoecon Outcomes Res"},{"key":"10.1016\/j.jclinane.2020.110027_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta14390","article-title":"Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment","volume":"14","author":"Chambers","year":"2010","journal-title":"Health Technol Assess"},{"key":"10.1016\/j.jclinane.2020.110027_bb0025","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1093\/bja\/aeq269","article-title":"Sugammadex compared with neostigmine\/glycopyrrolate for routine reversal of neuromuscular block: a systematic review and economic evaluation","volume":"105","author":"Paton","year":"2010","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0030","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/HCM.0000000000000214","article-title":"Contributors to operating room underutilization and implications for hospital administrators","volume":"37","author":"Tankard","year":"2018","journal-title":"Health Care Manag (Frederick)"},{"key":"10.1016\/j.jclinane.2020.110027_bb0035","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jclinane.2010.02.003","article-title":"What does one minute of operating room time cost?","volume":"22","author":"Macario","year":"2010","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0040","doi-asserted-by":"crossref","DOI":"10.1001\/jamasurg.2017.6233","article-title":"Understanding costs of care in the operating room","volume":"153","author":"Childers","year":"2018","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0045","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1097\/01.CCM.0000164543.14619.00","article-title":"Daily cost of an intensive care unit day: the contribution of mechanical ventilation","volume":"33","author":"Dasta","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jclinane.2020.110027_bb0050","doi-asserted-by":"crossref","first-page":"106241","DOI":"10.1016\/j.dib.2020.106241","article-title":"Data and meta-analysis for choosing sugammadex or neostigmine for routine reversal of rocuronium block in adult patients","volume":"32","author":"Hurford","year":"2020","journal-title":"Data Brief"},{"key":"10.1016\/j.jclinane.2020.110027_bb0055","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s12630-011-9660-x","article-title":"A time-motion economic analysis of postoperative nausea and vomiting in ambulatory surgery","volume":"59","author":"Parra-Sanchez","year":"2012","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0060","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1213\/01.ane.0000248224.42707.48","article-title":"Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine","volume":"104","author":"Sacan","year":"2007","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0065","first-page":"917","article-title":"Comparison of the cost-effectiveness of sugammadex and neostigmine during general anaesthesia for laparoscopic cholecystectomy","volume":"103","author":"Grintescu","year":"2009","journal-title":"BJA: Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0070","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1097\/EJA.0b013e32833d56b7","article-title":"Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial","volume":"27","author":"Blobner","year":"2010","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0075","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1097\/ALN.0b013e3181f4182a","article-title":"Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block","volume":"113","author":"Schaller","year":"2010","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0080","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/s00540-011-1209-1","article-title":"Intraoperative reversal of neuromuscular block with sugammadex or neostigmine during extreme lateral interbody fusion, a novel technique for spine surgery","volume":"25","author":"Adamus","year":"2011","journal-title":"J Anesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0085","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1213\/ANE.0b013e3181fdf889","article-title":"The duration of residual neuromuscular block after administration of neostigmine or sugammadex at two visible twitches during train-of-four monitoring","volume":"112","author":"Illman","year":"2011","journal-title":"Anesth Analg"},{"issue":"140","key":"10.1016\/j.jclinane.2020.110027_bb0090","article-title":"Residual neuromuscular blockade at extubation: a randomized comparison of sugammadex and neostigmine reversal of rocuronium-induced blockade in patients undergoing abdominal surgery","volume":"2","author":"Sabo","year":"2011","journal-title":"J Anesth Clinic Res"},{"key":"10.1016\/j.jclinane.2020.110027_bb0095","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/bja\/aer330","article-title":"Randomized comparison of sugammadex and neostigmine for reversal of rocuronium-induced muscle relaxation in morbidly obese undergoing general anaesthesia","volume":"108","author":"Gaszynski","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0100","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.egja.2011.12.007","article-title":"Improved recovery profiles in sinonasal surgery: Sugammadex: does it have a role?","volume":"28","author":"Mekawy","year":"2012","journal-title":"Egypt J. Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0105","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1007\/s11695-013-0926-y","article-title":"Sugammadex allows fast-track bariatric surgery","volume":"23","author":"Carron","year":"2013","journal-title":"Obes Surg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0110","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00003643-201306001-00441","article-title":"Clinical and cost-effectiveness of sugammadex versus neostigmine reversal of rocuronium-induced neuromuscular block in super obese patients undergoing open laparotomy for bariatric surgery. A randomized controlled trial: 9AP1-7","volume":"30","author":"Georgiou","year":"2013","journal-title":"Eur J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0115","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/ALN.0b013e318297ce95","article-title":"Reversal of neuromuscular blockade with sugammadex at the reappearance of four twitches to train-of-four stimulation","volume":"119","author":"Pongracz","year":"2013","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0120","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4097\/kjae.2013.65.6.501","article-title":"Sugammadex versus neostigmine reversal of moderate rocuronium-induced neuromuscular blockade in Korean patients","volume":"65","author":"Woo","year":"2013","journal-title":"Korean J Anesthesiol"},{"issue":"53","key":"10.1016\/j.jclinane.2020.110027_bb0125","article-title":"Rocuronium blockade reversal with sugammadex vs. neostigmine: randomized study in Chinese and Caucasian subjects","volume":"14","author":"Wu","year":"2014","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0130","doi-asserted-by":"crossref","first-page":"547","DOI":"10.4097\/kjae.2015.68.6.547","article-title":"The combination of sugammadex and neostigmine can reduce the dosage of sugammadex during recovery from the moderate neuromuscular blockade","volume":"68","author":"Cheong","year":"2015","journal-title":"Korean J Anesthesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0135","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00003643-201206001-00081","article-title":"Comparison of sugammadex and neostigmine for reversal of rocuronium-induced muscle relaxation in short term elective surgery: 1AP8-2","volume":"29","author":"Koc","year":"2012","journal-title":"Eur J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0140","doi-asserted-by":"crossref","first-page":"387","DOI":"10.5152\/TJAR.2015.35682","article-title":"Comparison of sugammadex versus neostigmine costs and respiratory complications in patients with obstructive sleep apnoea","volume":"43","author":"Unal","year":"2015","journal-title":"Turk J Anaesthesiol Reanim"},{"key":"10.1016\/j.jclinane.2020.110027_bb0145","first-page":"1219","article-title":"Intraocular pressure changes associated with tracheal extubation: comparison of sugammadex with conventional reversal of neuromuscular blockade","volume":"65","author":"Yagan","year":"2015","journal-title":"J Pak Med Assoc"},{"key":"10.1016\/j.jclinane.2020.110027_bb0150","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2147\/CEOR.S109951","article-title":"The use of sugammadex for bariatric surgery: analysis of recovery time from neuromuscular blockade and possible economic impact","volume":"8","author":"De Robertis","year":"2016","journal-title":"Clinicoecon Outcomes Res"},{"key":"10.1016\/j.jclinane.2020.110027_bb0155","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/bja\/aev437","article-title":"Sugammadex and neostigmine dose-finding study for reversal of residual neuromuscular block at a train-of-four ratio of 0.2 (SUNDRO20)","volume":"116","author":"Kaufhold","year":"2016","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0160","first-page":"22","article-title":"Efficacy and safety of sugammadex in reversing nmb (rocuronium) in adults","volume":"10","author":"El Sherbeny","year":"2017","journal-title":"New York Sci J"},{"key":"10.1016\/j.jclinane.2020.110027_bb0165","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1097\/00000542-200604000-00009","article-title":"Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study","volume":"104","author":"Sorgenfrei","year":"2006","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0170","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1097\/01.anes.0000265152.78943.74","article-title":"Early reversal of profound rocuronium-induced neuromuscular blockade by sugammadex in a randomized multicenter study: efficacy, safety, and pharmacokinetics","volume":"106","author":"Sparr","year":"2007","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0175","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1093\/bja\/aeq226","article-title":"Sugammadex rapidly reverses moderate rocuronium- or vecuronium-induced neuromuscular block during sevoflurane anaesthesia: a dose-response relationship","volume":"105","author":"Puhringer","year":"2010","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0180","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/ALN.0000000000000424","article-title":"Effect of reversal of neuromuscular blockade with sugammadex versus usual care on bleeding risk in a randomized study of surgical patients","volume":"121","author":"Rahe-Meyer","year":"2014","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0185","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/ALN.0b013e31818a3fee","article-title":"Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine","volume":"109","author":"Jones","year":"2008","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0195","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/SLE.0000000000000049","article-title":"Sugammadex reduces postoperative pain after laparoscopic bariatric surgery: a randomized trial","volume":"24","author":"Castro","year":"2014","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"10.1016\/j.jclinane.2020.110027_bb0200","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/bja\/aev104","article-title":"Effects of sugammadex on incidence of postoperative residual neuromuscular blockade: a randomized, controlled study","volume":"115","author":"Brueckmann","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0205","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jclinane.2014.08.010","article-title":"Comparison of sugammadex and conventional reversal on postoperative nausea and vomiting: a randomized, blinded trial","volume":"27","author":"Koyuncu","year":"2015","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0210","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/anae.14174","article-title":"Recovery characteristics of patients receiving either sugammadex or neostigmine and glycopyrrolate for reversal of neuromuscular block: a randomised controlled trial","volume":"73","author":"Paech","year":"2018","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jclinane.2020.110027_bb0215","first-page":"735","article-title":"Prospective study of residual neuromuscular block and postoperative respiratory complications in patients reversed with neostigmine versus sugammadex","volume":"82","author":"Martinez-Ubieto","year":"2016","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0220","doi-asserted-by":"crossref","first-page":"248","DOI":"10.23736\/S0375-9393.16.11489-0","article-title":"The effect of routine availability of sugammadex on postoperative respiratory complications: a historical cohort study","volume":"83","author":"Olesnicky","year":"2017","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0225","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/ALN.0000000000001893","article-title":"Neostigmine administration after spontaneous recovery to a train-of-four ratio of 0.9 to 1.0: a randomized controlled trial of the effect on neuromuscular and clinical recovery","volume":"128","author":"Murphy","year":"2018","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2020.110027_bb0230","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12871-016-0281-3","article-title":"A discrete event simulation model of clinical and operating room efficiency outcomes of sugammadex versus neostigmine for neuromuscular block reversal in Canada","volume":"16","author":"Insinga","year":"2016","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.jclinane.2020.110027_bb0235","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1213\/ANE.0000000000004028","article-title":"The effects of postoperative residual neuromuscular blockade on hospital costs and intensive care unit admission: a population-based cohort study","volume":"128","author":"Grabitz","year":"2019","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0240","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1093\/bja\/aeq270","article-title":"Sugammadex for reversal of neuromuscular block after rapid sequence intubation: a systematic review and economic assessment","volume":"105","author":"Chambers","year":"2010","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0245","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1213\/01.ane.0000266495.79050.b0","article-title":"An observational study of surgeons' sequencing of cases and its impact on postanesthesia care unit and holding area staffing requirements at hospitals","volume":"105","author":"Marcon","year":"2007","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0250","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1213\/ANE.0000000000000773","article-title":"Anesthesia workload nationally during regular workdays and weekends","volume":"121","author":"Dexter","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0255","article-title":"Throughout the United States, pediatric patients undergoing ambulatory surgery enter the operating room and are discharged earlier in the day than are adults","volume":"16","author":"Dexter","year":"2019","journal-title":"Perioper Care Oper Room Manag"},{"key":"10.1016\/j.jclinane.2020.110027_bb0260","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1213\/ANE.0b013e3182a44d86","article-title":"Increased mean time from end of surgery to operating room exit in a historical cohort of cases with prolonged time to extubation","volume":"117","author":"Dexter","year":"2013","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2020.110027_bb0265","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1007\/s12630-013-0025-5","article-title":"Cohort study of cases with prolonged tracheal extubation times to examine the relationship with duration of workday","volume":"60","author":"Epstein","year":"2013","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0270","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jclinane.2017.03.004","article-title":"Role of sugammadex in accelerating postoperative discharge: a meta-analysis","volume":"39","author":"Carron","year":"2017","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2020.110027_bb0275","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S2213-2600(18)30294-7","article-title":"Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study","volume":"7","author":"Kirmeier","year":"2019","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jclinane.2020.110027_bb0280","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1097\/ALN.0000000000003256","article-title":"Sugammadex versus neostigmine for reversal of neuromuscular blockade and postoperative pulmonary complications (STRONGER): a multicenter matched cohort analysis","volume":"132","author":"Kheterpal","year":"2020","journal-title":"Anesthesiology"}],"container-title":["Journal of Clinical Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818020311508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818020311508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:17:22Z","timestamp":1760606242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952818020311508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":55,"alternative-id":["S0952818020311508"],"URL":"https:\/\/doi.org\/10.1016\/j.jclinane.2020.110027","relation":{},"ISSN":["0952-8180"],"issn-type":[{"value":"0952-8180","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sugammadex versus neostigmine for routine reversal of rocuronium block in adult patients: A cost analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jclinane.2020.110027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110027"}}