{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T21:53:42Z","timestamp":1789077222990,"version":"build-2803163510"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Anesthesia"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jclinane.2025.112062","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T21:58:22Z","timestamp":1762207102000},"page":"112062","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Efficacy and safety of intravenous iron supplementation for perioperative iron deficiency anemia: a systematic review and network meta-analysis of randomized controlled trials"],"prefix":"10.1016","volume":"108","author":[{"given":"Qingxia","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhicong","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fudong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjun","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jclinane.2025.112062_bb0005","doi-asserted-by":"crossref","first-page":"e713","DOI":"10.1016\/S2352-3026(23)00160-6","article-title":"Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990\u20132021: findings from the Global Burden of Disease Study 2021","volume":"10","year":"2023","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0010","doi-asserted-by":"crossref","first-page":"7242","DOI":"10.3748\/wjg.v26.i45.7242","article-title":"Diagnosis and treatment of iron-deficiency anemia in gastrointestinal bleeding: a systematic review","volume":"26","author":"Cotter","year":"2020","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0015","first-page":"252","article-title":"Multidisciplinary expert's consensus on the management of perioperative iron deficiency anemia in patients accepting general surgery","volume":"58","author":"Chinese Surgical Society, Editorial Board of Chinese Journal of Surgery","year":"2020","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"10.1016\/j.jclinane.2025.112062_bb0020","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/ALN.0000000000003870","article-title":"Anemia: perioperative risk and treatment opportunity","volume":"135","author":"Hare","year":"2021","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2025.112062_bb0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jss.2019.08.023","article-title":"The effect of perioperative intravenous iron on hemoglobin in surgical patients: a meta-analysis","volume":"246","author":"Koo","year":"2020","journal-title":"J Surg Res"},{"key":"10.1016\/j.jclinane.2025.112062_bb0030","article-title":"Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials","volume":"347","author":"Litton","year":"2013","journal-title":"BMJ (Clin Res Ed)"},{"key":"10.1016\/j.jclinane.2025.112062_bb0035","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1213\/ANE.0000000000002591","article-title":"Intravenous Iron for treatment of Anemia in the 3 perisurgical phases: a review and analysis of the current literature","volume":"126","author":"Peters","year":"2018","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0040","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1097\/ALN.0000000000005111","article-title":"Diagnosis and treatment of perioperative Anemia: a Society for Perioperative Assessment and Quality Improvement Collaborative Review","volume":"141","author":"Kumar","year":"2024","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2025.112062_bb0045","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/SLA.0000000000005721","article-title":"Recommendations from the international consensus conference on Anemia Management in Surgical Patients (ICCAMS)","volume":"277","author":"Shander","year":"2023","journal-title":"Ann Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0050","series-title":"Guideline for Management of Anaemia in the perioperative pathway","year":"2022"},{"key":"10.1016\/j.jclinane.2025.112062_bb0055","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/bjh.19440","article-title":"Identification and management of preoperative anaemia in adults: a British Society for Haematology guideline update","volume":"205","author":"Hands","year":"2024","journal-title":"Br J Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0060","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/EJA.0000000000001803","article-title":"Management of severe peri-operative bleeding: guidelines from the European Society of Anaesthesiology and Intensive Care: second update 2022","volume":"40","author":"Kietaibl","year":"2023","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0065","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1111\/anae.14358","article-title":"An international consensus statement on the management of postoperative anaemia after major surgical procedures","volume":"73","author":"Mu\u00f1oz","year":"2018","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jclinane.2025.112062_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.633","article-title":"Perioperative intravenous iron to treat patients with fractured hip surgery: a systematic review and meta-analysis","volume":"5","author":"Sinclair","year":"2022","journal-title":"Health Sci Rep"},{"key":"10.1016\/j.jclinane.2025.112062_bb0075","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1007\/s12325-021-01628-7","article-title":"Preoperative anemia treatment with intravenous iron therapy in patients undergoing abdominal surgery: a systematic review","volume":"38","author":"Moon","year":"2021","journal-title":"Adv Ther"},{"key":"10.1016\/j.jclinane.2025.112062_bb0080","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jclinepi.2010.03.016","article-title":"Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial","volume":"64","author":"Salanti","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0085","first-page":"557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ (Clin Res Ed)"},{"key":"10.1016\/j.jclinane.2025.112062_bb0090","series-title":"Cochrane handbook for systematic reviews ofInterventions","author":"Higgins","year":"2019"},{"key":"10.1016\/j.jclinane.2025.112062_bb0095","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.jclinepi.2003.12.001","article-title":"Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors","volume":"57","author":"Schmid","year":"2004","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0100","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/sim.1187","article-title":"How should meta-regression analyses be undertaken and interpreted?","volume":"21","author":"Thompson","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0105","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.d4002","article-title":"Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials","volume":"343","author":"Sterne","year":"2011","journal-title":"BMJ (Clin Res Ed)"},{"key":"10.1016\/j.jclinane.2025.112062_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta25110","article-title":"Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT","volume":"25","author":"Richards","year":"2021","journal-title":"Health Technol Assess"},{"key":"10.1016\/j.jclinane.2025.112062_bb0115","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1111\/jog.13893","article-title":"Comparative efficacy and safety of intravenous ferric carboxymaltose and iron sucrose for the treatment of preoperative anemia in patients with menorrhagia: an open-label, multicenter, randomized study","volume":"45","author":"Lee","year":"2019","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.jclinane.2025.112062_bb0120","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1001\/jama.2017.5703","article-title":"Effect of intravenous ferric Carboxymaltose on hemoglobin response among patients with acute Isovolemic Anemia following gastrectomy: the FAIRY randomized clinical trial","volume":"217","author":"Kim","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.jclinane.2025.112062_bb0125","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/ageing\/afaa107","article-title":"Effect of intravenous iron on functional outcomes in hip fracture: a randomised controlled trial","volume":"50","author":"Bielza","year":"2021","journal-title":"Age Ageing"},{"key":"10.1016\/j.jclinane.2025.112062_bb0130","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.3390\/jcm12051737","article-title":"Effect of preoperative Administration of Intravenous Ferric Carboxymaltose in patients with Iron deficiency Anemia after off-pump coronary artery bypass grafting: a randomized controlled trial","volume":"12","author":"Kim","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0135","article-title":"Effects of ferric carboxymaltose on hemoglobin level after cardiac surgery: a randomized controlled trial","volume":"42","author":"Houry","year":"2023","journal-title":"Anaesth Crit Care Pain Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0140","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.3390\/jcm10071457","article-title":"Efficacy and safety of intravenous ferric Carboxymaltose in patients with postoperative Anemia following same-day bilateral Total knee arthroplasty: a randomized controlled trial","volume":"10","author":"Kim","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0145","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/EJA.0000000000001389","article-title":"Efficacy of intra-operative administration of iron isomaltoside for preventing postoperative anaemia after total knee arthroplasty: a randomised controlled trial","volume":"38","author":"Yoo","year":"2021","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0150","doi-asserted-by":"crossref","first-page":"e250","DOI":"10.1016\/S2352-3026(22)00402-1","article-title":"Ferric carboxymaltose infusion versus oral iron supplementation for preoperative iron deficiency anaemia in patients with colorectal cancer (FIT): a multicentre, open-label, randomised, controlled trial","volume":"10","author":"Talboom","year":"2023","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0155","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1111\/trf.13624","article-title":"Ferric carboxymaltose with or without erythropoietin in anemic patients with hip fracture: a randomized clinical trial","volume":"56","author":"Bernabeu-Wittel","year":"2016","journal-title":"Transfusion"},{"key":"10.1016\/j.jclinane.2025.112062_bb0160","doi-asserted-by":"crossref","first-page":"e747","DOI":"10.1016\/S2352-3026(23)00163-1","article-title":"Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial): a multicentre, 2\u00d72 factorial, randomised, double-blind, controlled trial","volume":"10","author":"Lasocki","year":"2023","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0165","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.3390\/jcm11092357","article-title":"Intravenous ferric Carboxymaltose improves response to postoperative Anemia following total knee arthroplasty: a prospective randomized controlled trial in Asian cohort","volume":"11","author":"Choi","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0170","doi-asserted-by":"crossref","first-page":"e415","DOI":"10.1016\/S2352-3026(16)30078-3","article-title":"Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial","volume":"3","author":"Khalafallah","year":"2016","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0175","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.bja.2023.09.007","article-title":"Intravenous iron administration before cardiac surgery reduces red blood cell transfusion in patients without anaemia","volume":"131","author":"Friedman","year":"2023","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2025.112062_bb0180","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/icvts\/ivy226","article-title":"Intravenous iron does not effectively correct preoperative anaemia in cardiac surgery: a pilot randomized controlled trial","volume":"28","author":"Padmanabhan","year":"2019","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0185","first-page":"1494","volume":"14","author":"Akshata","year":"2023","journal-title":"J Cardiovasc Dis Res"},{"key":"10.1016\/j.jclinane.2025.112062_bb0190","doi-asserted-by":"crossref","first-page":"141","DOI":"10.4103\/aca.aca_209_20","article-title":"Intravenous iron supplementation treats anemia and reduces blood transfusion requirements in patients undergoing coronary artery bypass grafting-a prospective randomized trial","volume":"25","author":"Shokri","year":"2022","journal-title":"Ann Card Anaesth"},{"key":"10.1016\/j.jclinane.2025.112062_bb0195","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1053\/j.jvca.2019.01.063","article-title":"Intravenous iron versus placebo in the Management of Postoperative Functional Iron Deficiency Anemia in patients undergoing cardiac valvular surgery: a prospective, single-blinded, randomized controlled trial","volume":"33","author":"Xu","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.jclinane.2025.112062_bb0200","article-title":"IRON NOF trial: IV iron for anaemic patients with femoral fracture","volume":"12","author":"O\u2019Loughlin","year":"2023","journal-title":"BJA Open"},{"key":"10.1016\/j.jclinane.2025.112062_bb0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0270640","article-title":"Perioperative changes in haemoglobin and ferritin concentrations from preoperative intravenous iron isomaltoside for iron deficiency anaemia in patients with colorectal cancer: a pilot randomised controlled trial","volume":"17","author":"Fung","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.jclinane.2025.112062_bb0210","article-title":"Preoperative single-dose intravenous Iron formulation to reduce postsurgical complications in patients undergoing major abdominal surgery: a randomized control trial feasibility study (PIRCAS trial pilot)","volume":"13","author":"Thin","year":"2021","journal-title":"Cureus"},{"key":"10.1016\/j.jclinane.2025.112062_bb0215","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/bjs.6688","article-title":"Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery","volume":"96","author":"Edwards","year":"2009","journal-title":"Br J Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0220","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/bjs.10328","article-title":"Randomized clinical trial of preoperative oral versus intravenous iron in anaemic patients with colorectal cancer","volume":"104","author":"Keeler","year":"2017","journal-title":"Br J Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0225","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1111\/anae.14659","article-title":"The impact of pre-operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer-associated anaemia (IVICA) trial","volume":"74","author":"Keeler","year":"2019","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jclinane.2025.112062_bb0230","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1093\/bja\/aeu092","article-title":"Randomized trial comparing ferric carboxymaltose vs oral ferrous glycine sulphate for postoperative anaemia after total knee arthroplasty","volume":"113","author":"Bisbe","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2025.112062_bb0235","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1537-2995.2010.02769.x","article-title":"Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial","volume":"51","author":"Serrano-Trenas","year":"2011","journal-title":"Transfusion"},{"key":"10.1016\/j.jclinane.2025.112062_bb0240","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000210062","article-title":"Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study","volume":"121","author":"Kim","year":"2009","journal-title":"Acta Haematol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0245","first-page":"310","article-title":"Single-dose intravenous ferric carboxymaltose infusion versus multiple fractionated doses of intravenous iron sucrose in the treatment of post-operative anaemia in colorectal cancer patients: a randomised controlled trial","volume":"20","author":"Laso-Morales","year":"2022","journal-title":"Blood Transfus"},{"key":"10.1016\/j.jclinane.2025.112062_bb0250","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.3390\/jcm8101674","article-title":"The effect of intraoperative ferric carboxymaltose in joint arthroplasty patients: a randomized trial","volume":"8","author":"Kim","year":"2019","journal-title":"J Clin Med"},{"key":"10.1016\/j.jclinane.2025.112062_bb0255","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/icvts\/ivs344","article-title":"The effect of intravenous and oral iron administration on perioperative anaemia and transfusion requirements in patients undergoing elective cardiac surgery: a randomized clinical trial","volume":"15","author":"Garrido-Mart\u00edn","year":"2012","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0260","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1093\/ageing\/afz049","article-title":"The effect of intravenous iron on erythropoiesis in older people with hip fracture","volume":"48","author":"Moppett","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.jclinane.2025.112062_bb0265","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/SLA.0000000000001646","article-title":"The important role for intravenous Iron in perioperative patient blood Management in Major Abdominal Surgery: a randomized controlled trial","volume":"264","author":"Froessler","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0270","doi-asserted-by":"crossref","first-page":"15853","DOI":"10.1038\/s41598-020-72827-5","article-title":"A randomised trial evaluating the effect of intraoperative iron administration","volume":"10","author":"Lee","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.jclinane.2025.112062_bb0275","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/vox.12278","volume":"109","author":"Johansson","year":"2015","journal-title":"Vox Sang"},{"key":"10.1016\/j.jclinane.2025.112062_bb0280","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/ejhf.2557","article-title":"Intravenous iron supplement for iron deficiency in patients with severe aortic stenosis scheduled for transcatheter aortic valve implantation: results of the IIISAS randomised trial","volume":"24","author":"Kvaslerud","year":"2022","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jclinane.2025.112062_bb0285","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.3390\/ijms22031008","article-title":"Iron therapy in chronic kidney disease: days of future past","volume":"22","author":"Lee","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jclinane.2025.112062_bb0290","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jrp.2013.05.009","article-title":"At what sample size do correlations stabilize?","volume":"47","author":"Felix","year":"2013","journal-title":"J Res Pers"},{"key":"10.1016\/j.jclinane.2025.112062_bb0295","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/anae.13773","article-title":"International consensus statement on the peri-operative management of anaemia and iron deficiency","volume":"72","author":"Mu\u00f1oz","year":"2017","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jclinane.2025.112062_bb0300","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S1010-7940(01)01099-5","article-title":"Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update","volume":"21","author":"Paparella","year":"2002","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0305","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/nri3863","article-title":"Iron homeostasis in host defence and inflammation","volume":"15","author":"Ganz","year":"2015","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0310","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/ALN.0000000000000463","article-title":"Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management*","volume":"122","author":"American Society of Anesthesiologists Task Force on Perioperative Blood Management","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2025.112062_bb0315","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1097\/EJA.0000000000000630","article-title":"Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology: first update 2016","volume":"34","author":"Kozek-Langenecker","year":"2017","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0320","first-page":"261","article-title":"Peri-operative blood transfusion in elective major surgery: incidence, indications and outcome - an observational multicentre study","volume":"18","author":"Unal","year":"2020","journal-title":"Blood Transfus"},{"key":"10.1016\/j.jclinane.2025.112062_bb0325","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1046\/j.1525-139x.2000.00104.x","article-title":"The comparative safety of intravenous iron dextran, iron saccharate, and sodium ferric gluconate","volume":"13","author":"Fishbane","year":"2000","journal-title":"Semin Dial"},{"key":"10.1016\/j.jclinane.2025.112062_bb0330","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s10534-015-9845-9","article-title":"Physico-chemical properties of the new generation IV iron preparations ferumoxytol, iron isomaltoside 1000 and ferric carboxymaltose","volume":"28","author":"Neiser","year":"2015","journal-title":"Biometals"},{"key":"10.1016\/j.jclinane.2025.112062_bb0335","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s11096-023-01548-2","article-title":"A systematic literature review and meta-analysis of the incidence of serious or severe hypersensitivity reactions after administration of ferric derisomaltose or ferric carboxymaltose","volume":"45","author":"Kennedy","year":"2023","journal-title":"Int J Clin Pharm"},{"key":"10.1016\/j.jclinane.2025.112062_bb0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijsu.2022.106759","article-title":"Incidence, patterns and risk factors for readmission following knee arthroplasty in China: a national retrospective cohort study","volume":"104","author":"Long","year":"2022","journal-title":"Int J Surg"},{"key":"10.1016\/j.jclinane.2025.112062_bb0345","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12871-025-02898-2","article-title":"Outcome and complications in postcardiotomy cardiogenic shock treated with extracorporeal life support - a systematic review and meta-analysis","volume":"25","author":"Kienlein","year":"2025","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.jclinane.2025.112062_bb0350","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/j.1537-2995.2006.00859.x","article-title":"Perioperative intravenous iron, with or without erythropoietin, plus restrictive transfusion protocol reduce the need for allogeneic blood after knee replacement surgery","volume":"46","author":"Cuenca","year":"2006","journal-title":"Transfusion"},{"key":"10.1016\/j.jclinane.2025.112062_bb0355","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.tmrv.2013.09.001","article-title":"Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review","volume":"27","author":"Lin","year":"2013","journal-title":"Transfus Med Rev"}],"container-title":["Journal of Clinical Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095281802500323X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095281802500323X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T20:23:30Z","timestamp":1768854210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095281802500323X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":71,"alternative-id":["S095281802500323X"],"URL":"https:\/\/doi.org\/10.1016\/j.jclinane.2025.112062","relation":{},"ISSN":["0952-8180"],"issn-type":[{"value":"0952-8180","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of intravenous iron supplementation for perioperative iron deficiency anemia: a systematic review and network meta-analysis of randomized controlled trials","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jclinane.2025.112062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112062"}}