{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:51:14Z","timestamp":1791661874492,"version":"4.3.4"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100003305","name":"ResMed Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003305","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000226","name":"Ontario Ministry of Health and Long-Term Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009663","name":"University Health Network","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Anesthesia"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.jclinane.2026.112336","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:10:04Z","timestamp":1791461404000},"page":"112336","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Difficulty climbing stairs or walking one block on the FRAIL scale is associated with adverse postoperative outcomes in older surgical patients"],"prefix":"10.1016","volume":"116","author":[{"given":"Tony","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellene","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Alhamdah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Nabipoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Butris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paras","family":"Kapoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna","family":"Saripella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sazzadul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jclinane.2026.112336_bb0005","doi-asserted-by":"crossref","DOI":"10.3389\/fragi.2025.1520842","article-title":"From frailty to resilience: exploring adaptive capacity and reserve in older adults\u2013a narrative review","volume":"6","author":"Cosarderelioglu","year":"2025","journal-title":"Front Aging"},{"key":"10.1016\/j.jclinane.2026.112336_bb0010","article-title":"Relationship between preoperative malnutrition, frailty, sarcopenia, body composition, and anthropometry in elderly patients undergoing major pancreatic and biliary surgery","volume":"10","author":"Wang","year":"2023","journal-title":"Front Nutr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s40520-025-02956-2","article-title":"Frailty as an independent risk factor for sepsis-associated delirium: a cohort study of 11,740 older adult ICU patients","volume":"37","author":"Zheng","year":"2025","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.jclinane.2026.112336_bb0020","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1213\/ANE.0000000000006272","article-title":"Association between the FRAIL scale and postoperative complications in older surgical patients: a systematic review and Meta-analysis","volume":"136","author":"Gong","year":"2023","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jclinane.2026.112336_bb0025","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.gerinurse.2024.08.013","article-title":"Prediction of postoperative mortality in older surgical patients by clinical frailty scale: a systematic review and meta-analysis","volume":"59","author":"Zhang","year":"2024","journal-title":"Geriatr Nurs"},{"key":"10.1016\/j.jclinane.2026.112336_bb0030","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12877-024-05615-9","article-title":"Application and implementation of brief geriatric assessment in primary care and community settings: a scoping review","volume":"25","author":"Lau","year":"2025","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0035","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1100\/tsw.2001.58","article-title":"Accumulation of deficits as a proxy measure of aging","volume":"1","author":"Mitnitski","year":"2001","journal-title":"ScientificWorldJournal"},{"key":"10.1016\/j.jclinane.2026.112336_bb0040","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1503\/cmaj.050051","article-title":"A global clinical measure of fitness and frailty in elderly people","volume":"173","author":"Rockwood","year":"2005","journal-title":"CMAJ"},{"key":"10.1016\/j.jclinane.2026.112336_bb0045","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF02982161","article-title":"The I.A.N.A task force on frailty assessment of older people in clinical practice","volume":"12","author":"Abellan van Kan","year":"2008","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.jclinane.2026.112336_bb0050","doi-asserted-by":"crossref","first-page":"607.e7","DOI":"10.1016\/j.jamda.2020.09.024","article-title":"A comparison of frailty assessment instruments in different clinical and social care settings: the Frailtools project","volume":"22","author":"Oviedo-Briones","year":"2021","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.jclinane.2026.112336_bb0055","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1056\/NEJMra2301292","article-title":"Frailty in older adults","volume":"391","author":"Kim","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jclinane.2026.112336_bb0060","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14061808","article-title":"Frailty in geriatrics: a critical review with content analysis of instruments, overlapping constructs, and challenges in diagnosis and prognostic precision","volume":"14","author":"Fierro-Marrero","year":"2025","journal-title":"J Clin Med"},{"key":"10.1016\/j.jclinane.2026.112336_bb0065","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12957-025-03924-w","article-title":"Analysis of frailty change trajectories and its risk factors in patients with gastrointestinal tumor surgery: a prospective observational longitudinal study","volume":"23","author":"You","year":"2025","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.jclinane.2026.112336_bb0070","article-title":"The prevalence and trajectory of frailty in older surgical patients: a longitudinal multicentre cohort study","author":"Lu","year":"2025","journal-title":"Anaesth Crit Care Pain Med"},{"key":"10.1016\/j.jclinane.2026.112336_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2025.112015","article-title":"The perioperative impact of frailty and cognitive impairment in older surgical patients: a multicentered longitudinal cohort study","volume":"107","author":"Cheuk","year":"2025","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0080","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12871-025-02994-3","article-title":"Unraveling the impact of frailty on postoperative delirium in elderly surgical patients: a systematic review and meta-analysis","volume":"25","author":"Wu","year":"2025","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.jclinane.2026.112336_bb0085","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12877-025-05716-z","article-title":"Association between frailty, as measured by the FRAIL scale, and 1-year mortality in older patients undergoing hip fracture surgery","volume":"25","author":"Xi","year":"2025","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2024.111681","article-title":"Evaluating prevalence and trajectory of functional disability in older surgical patients: an observational cohort study","volume":"99","author":"Yan","year":"2024","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2025.111940","article-title":"The utility of the ascertain dementia eight-item questionnaire (AD8) and Mini-cog in detecting cognitive impairment in older surgical patients \u2013 the detect CI study","volume":"106","author":"Yan","year":"2025","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2026.112256","article-title":"Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients","volume":"113","author":"Yan","year":"2026","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0105","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s12603-012-0084-2","article-title":"A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans","volume":"16","author":"Morley","year":"2012","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.jclinane.2026.112336_bb0110","doi-asserted-by":"crossref","DOI":"10.1177\/03000605241274553","article-title":"Preoperative frailty and postoperative complications after non-cardiac surgery: a systematic review","volume":"52","author":"Becerra-Bola\u00f1os","year":"2024","journal-title":"J Int Med Res"},{"key":"10.1016\/j.jclinane.2026.112336_bb0115","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1007\/s00595-024-02807-z","article-title":"Impact of frailty and prefrailty on the mid-term outcomes and rehabilitation course after cardiac surgery","volume":"54","author":"Honda","year":"2024","journal-title":"Surg Today"},{"key":"10.1016\/j.jclinane.2026.112336_bb0120","doi-asserted-by":"crossref","first-page":"941","DOI":"10.7326\/0003-4819-113-12-941","article-title":"Clarifying confusion: the confusion assessment method","volume":"113","author":"Inouye","year":"1990","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jclinane.2026.112336_bb0125","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1532-5415.2005.53120.x","article-title":"A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method","volume":"53","author":"Inouye","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jclinane.2026.112336_bb0130","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Ser B Stat Methodol"},{"key":"10.1016\/j.jclinane.2026.112336_bb0135","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1186\/s12877-025-05966-x","article-title":"Effects of sarcopenia on postoperative recovery in elderly patients after cardiac surgery with cardiopulmonary bypass","volume":"25","author":"Wang","year":"2025","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0140","doi-asserted-by":"crossref","first-page":"243","DOI":"10.14245\/ns.2449364.682","article-title":"Prevalence and risk factors for postoperative neurological complications in spinal deformity surgery: a systematic review and proportional Meta-analysis","volume":"22","author":"Man","year":"2025","journal-title":"Neurospine"},{"key":"10.1016\/j.jclinane.2026.112336_bb0145","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1113\/EP090156","article-title":"\u2018Fit for surgery\u2019: the relationship between cardiorespiratory fitness and postoperative outcomes","volume":"107","author":"Rose","year":"2022","journal-title":"Exp Physiol"},{"key":"10.1016\/j.jclinane.2026.112336_bb0150","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1111\/jgs.16846","article-title":"Association between patient-reported frailty and non-home discharge among older adults undergoing surgery","volume":"68","author":"Sokas","year":"2020","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jclinane.2026.112336_bb0155","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jamcollsurg.2012.06.017","article-title":"Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society","volume":"215","author":"Chow","year":"2012","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jclinane.2026.112336_bb0160","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.bja.2020.10.037","article-title":"Improving perioperative brain health: an expert consensus review of key actions for the perioperative care team","volume":"126","author":"Peden","year":"2021","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0165","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/ALN.0000000000005172","article-title":"2025 American Society of Anesthesiologists practice advisory for perioperative care of older adults scheduled for inpatient surgery","volume":"142","author":"Sieber","year":"2025","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jclinane.2026.112336_bb0170","first-page":"919","article-title":"The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure","volume":"132","author":"Guyatt","year":"1985","journal-title":"Can Med Assoc J"},{"key":"10.1016\/j.jclinane.2026.112336_bb0175","doi-asserted-by":"crossref","first-page":"566","DOI":"10.4103\/sja.sja_628_23","article-title":"Anesthesia and perioperative pain relief in the frail elderly patient","volume":"17","author":"Van Zundert","year":"2023","journal-title":"Saudi J Anaesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.archger.2025.105783","article-title":"Protein supplementation alone or combined with exercise for sarcopenia and physical frailty: a systematic review and meta-analysis of randomized controlled trials","volume":"131","author":"Yoshimura","year":"2025","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0185","doi-asserted-by":"crossref","first-page":"344","DOI":"10.2519\/jospt.2025.13075","article-title":"The effects of structured Prehabilitation on postoperative outcomes following Total hip and Total knee arthroplasty: an overview of systematic reviews and Meta-analyses of randomized controlled trials","volume":"55","author":"Keogh","year":"2025","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.jclinane.2026.112336_bb0190","doi-asserted-by":"crossref","DOI":"10.1186\/s12877-025-05768-1","article-title":"Evidence on non-pharmacological interventions for preventing or reversing physical frailty in community-dwelling older adults aged over 50 years: overview of systematic reviews","volume":"25","author":"Money","year":"2025","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.jclinane.2026.112336_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2025.111895","article-title":"Understanding preoperative concerns and attitudes towards prehabilitation in older surgical populations: a survey study","volume":"105","author":"Li","year":"2025","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jclinane.2026.112336_bb0200","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/s12877-023-03990-3","article-title":"Barriers and facilitators to participation in exercise prehabilitation before cancer surgery for older adults with frailty: a qualitative study","volume":"23","author":"Barnes","year":"2023","journal-title":"BMC Geriatr"}],"container-title":["Journal of Clinical Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818026002151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0952818026002151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:30:51Z","timestamp":1791660651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0952818026002151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":40,"alternative-id":["S0952818026002151"],"URL":"https:\/\/doi.org\/10.1016\/j.jclinane.2026.112336","relation":{},"ISSN":["0952-8180"],"issn-type":[{"value":"0952-8180","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Difficulty climbing stairs or walking one block on the FRAIL scale is associated with adverse postoperative outcomes in older surgical patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jclinane.2026.112336","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"112336"}}