{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:05:06Z","timestamp":1792670706340,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":1117,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Imaging"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.jcmg.2010.03.013","type":"journal-article","created":{"date-parts":[[2010,8,11]],"date-time":"2010-08-11T05:17:24Z","timestamp":1281503844000},"page":"797-805","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Intravascular and Extravascular Microvessel Formation in Chronic Total Occlusions"],"prefix":"10.1016","volume":"3","author":[{"given":"Nigel R.","family":"Munce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley H.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuling","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max J.","family":"Weisbrod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevan J.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"General","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Sparkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Lockwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronen","family":"Jaffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagdish","family":"Butany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron A.","family":"Teitelbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beiping","family":"Qiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander J.","family":"Dick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham A.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmg.2010.03.013_bib1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0002-8703(93)90404-W","article-title":"Angiographic suitability for catheter revascularization of total coronary occlusions in patients from a community hospital setting","volume":"126","author":"Kahn","year":"1993","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcmg.2010.03.013_bib2","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.amjcard.2004.12.065","article-title":"Effect of chronic total coronary occlusion on treatment strategy","volume":"95","author":"Christofferson","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib3","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1161\/01.CIR.71.3.510","article-title":"The prevalence of peripheral arterial disease in a defined population","volume":"71","author":"Criqui","year":"1985","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2010.03.013_bib4","first-page":"134","article-title":"Prevalence of lower limb occlusive vascular disease in outclinic diabetic patients","volume":"23","author":"Andrade","year":"2004","journal-title":"Int Angiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib5","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1161\/CIRCULATIONAHA.104.481283","article-title":"Percutaneous recanalization of chronically occluded coronary arteries: a consensus document: part I","volume":"112","author":"Stone","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2010.03.013_bib6","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1016\/S0735-1097(03)00312-7","article-title":"Immediate results and one-year clinical outcome after percutaneous coronary interventions in chronic total occlusions: data from a multicenter, prospective, observational study (TOAST-GISE)","volume":"41","author":"Olivari","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib7","first-page":"772","article-title":"Late percutaneous coronary intervention for the totally occluded infarct-related artery: a meta-analysis of the effects on cardiac function and remodeling","volume":"71","author":"Appleton","year":"2008","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcmg.2010.03.013_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0735-1097(95)00156-T","article-title":"Percutaneous revascularization of chronic coronary occlusions: an overview","volume":"26","author":"Puma","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib9","first-page":"258","article-title":"Percutaneous transluminal coronary angioplasty of chronic total occlusions","volume":"49","author":"Noguchi","year":"2000","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcmg.2010.03.013_bib10","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0735-1097(97)00035-1","article-title":"Histologic correlates of angiographic chronic total coronary artery occlusions: influence of occlusion duration on neovascular channel patterns and intimal plaque composition","volume":"29","author":"Srivatsa","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib11","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/S0735-1097(98)00482-3","article-title":"Adventitial vasa vasorum in balloon-injured coronary arteries: visualization and quantitation by a microscopic three-dimensional computed tomography technique","volume":"32","author":"Kwon","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib12","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.jacc.2005.08.076","article-title":"Adventitial microvessel formation after coronary stenting and the effects of SU11218, a tyrosine kinase inhibitor","volume":"47","author":"Cheema","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib13","doi-asserted-by":"crossref","first-page":"6483","DOI":"10.2741\/3168","article-title":"Overexpression of hypoxia\/inflammatory markers in atherosclerotic carotid plaques","volume":"13","author":"Luque","year":"2008","journal-title":"Front Biosci"},{"key":"10.1016\/j.jcmg.2010.03.013_bib14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1540-8183.2005.00082.x","article-title":"Microvessels in chronic total occlusions: pathways for successful guidewire crossing?","volume":"18","author":"Strauss","year":"2005","journal-title":"J Interv Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib15","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/0735-1097(93)90091-E","article-title":"Histologic studies in percutaneous transluminal coronary angioplasty for chronic total occlusion: comparison of tapering and abrupt types of occlusion and short and long occluded segments","volume":"21","author":"Katsuragawa","year":"1993","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib16","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1118\/1.1637971","article-title":"MicroCT scanner performance and considerations for vascular specimen imaging","volume":"31","author":"Marxen","year":"2004","journal-title":"Med Phys"},{"key":"10.1016\/j.jcmg.2010.03.013_bib17","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.jacc.2008.09.064","article-title":"Natural history of experimental arterial chronic total occlusions","volume":"53","author":"Jaffe","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib18","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1161\/01.CIR.0000086320.24172.A1","article-title":"Collagenase plaque digestion for facilitating guide wire crossing in chronic total occlusions","volume":"108","author":"Strauss","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2010.03.013_bib19","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1161\/CIRCULATIONAHA.104.492678","article-title":"Endothelial progenitor cells are recruited into resolving venous thrombi","volume":"111","author":"Modarai","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2010.03.013_bib20","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/RLI.0b013e3181727519","article-title":"Longitudinal follow-up of cardiac structure and functional changes in an infarct mouse model using retrospectively gated micro-computed tomography","volume":"43","author":"Detombe","year":"2008","journal-title":"Invest Radiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib21","first-page":"283","article-title":"Immediate- and short-term outcome following recanalization of long chronic total occlusions (> 50 mm) of native coronary arteries with the Frontrunner catheter","volume":"18","author":"Loli","year":"2006","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.jcmg.2010.03.013_bib22","first-page":"29","article-title":"A novel approach to chronic total occlusions: the crosser system","volume":"68","author":"Melzi","year":"2006","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcmg.2010.03.013_bib23","first-page":"784","article-title":"Percutaneous coronary intervention for chronic total occlusion: novel 3-dimensional imaging and quantitative analysis","volume":"71","author":"Dvir","year":"2008","journal-title":"Catheter Cardiovasc Interv"}],"container-title":["JACC: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X10003487?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X10003487?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:37:30Z","timestamp":1761845850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936878X10003487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S1936878X10003487"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmg.2010.03.013","relation":{},"ISSN":["1936-878X"],"issn-type":[{"value":"1936-878X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intravascular and Extravascular Microvessel Formation in Chronic Total Occlusions","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2010.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}