{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:49:29Z","timestamp":1791146969028,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Imaging"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.jcmg.2015.02.009","type":"journal-article","created":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T21:04:26Z","timestamp":1431551066000},"page":"642-652","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":96,"title":["Right Intraventricular Dyssynchrony in Idiopathic, Heritable, and Anorexigen-Induced Pulmonary Arterial Hypertension"],"prefix":"10.1016","volume":"8","author":[{"given":"Roberto","family":"Badagliacca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Reali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Poscia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Pezzuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Papa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Mezzapesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Nocioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Valli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Giannetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Sciomer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Iacoboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fedele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmine Dario","family":"Vizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmg.2015.02.009_bib1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1378\/chest.08-1758","article-title":"Determinants of right ventricular ejection fraction in pulmonary arterial hypertension","volume":"135","author":"Kawut","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.jcmg.2015.02.009_bib2","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1161\/CIRCULATIONAHA.106.632208","article-title":"Right\u00a0ventricular function and failure: report of a\u00a0National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure","volume":"114","author":"Voelkel","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2015.02.009_bib3","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJMoa050496","article-title":"The effect of cardiac resynchronization on morbidity and mortality in heart failure","volume":"352","author":"Cleland","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2015.02.009_bib4","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.amjcard.2005.04.028","article-title":"Relation of right ventricular free wall mechanical delay to right ventricular dysfunction as determined by tissue Doppler imaging","volume":"96","author":"Lopez-Candales","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib5","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.echo.2008.05.005","article-title":"Evaluation of right intraventricular dyssynchrony by two-dimensional strain echocardiography in patients with pulmonary arterial hypertension","volume":"21","author":"Kalogeropoulos","year":"2008","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2015.02.009_bib6","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.jacc.2007.10.041","article-title":"Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling","volume":"51","author":"Marcus","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib7","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1093\/eurheartj\/ehp297","volume":"30","author":"Gali\u00e8","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2015.02.009_bib8","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1161\/CIRCULATIONAHA.109.911818","article-title":"Survival\u00a0in patients with idiopathic, familial, and\u00a0anorexigen-associated pulmonary arterial hypertension in the modern management era","volume":"122","author":"Humbert","year":"2010","journal-title":"Circulation"},{"issue":"Suppl 1","key":"10.1016\/j.jcmg.2015.02.009_bib9","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1016\/j.jacc.2009.04.007","article-title":"End points and clinical trial design in pulmonary arterial hypertension","volume":"54","author":"McLaughlin","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib10","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1164\/ajrccm.162.3.9910102","article-title":"Outcome of patients with cystic fibrosis awaiting lung transplantation","volume":"162","author":"Vizza","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcmg.2015.02.009_bib11","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","volume":"23","author":"Rudski","year":"2010","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2015.02.009_bib12","unstructured":"NTNU-Trondheim Norwegian University of Science and Technology Strain rate imaging. Available at: www.ntnu.edu\/isb\/echocardiography. Accessed June 1, 2014."},{"key":"10.1016\/j.jcmg.2015.02.009_bib13","first-page":"353","article-title":"An analysis of the time-relations of electrocardiograms","volume":"7","author":"Bazett","year":"1920","journal-title":"Heart"},{"key":"10.1016\/j.jcmg.2015.02.009_bib14","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics"},{"key":"10.1016\/j.jcmg.2015.02.009_bib15","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.healun.2012.04.004","article-title":"Electrical and mechanical dyssynchrony in pediatric pulmonary hypertension","volume":"31","author":"Hill","year":"2012","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jcmg.2015.02.009_bib16","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1161\/CIRCEP.109.856021","article-title":"Right-to-left ventricular diastolic delay in chronic thromboembolic pulmonary hypertension is associated with activation delay and action potential prolongation in right ventricle","volume":"2","author":"Hardziyenka","year":"2009","journal-title":"Circ Arrhythmia Electrophysiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/ejechocard\/jer021","article-title":"Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE\/EAE consensus statement on methodology and indications. Endorsed by the Japanese Society of Echocardiography","volume":"12","author":"Mor-Avi","year":"2011","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.jcmg.2015.02.009_bib18","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.jacc.2011.06.038","article-title":"Echocardiographic assessment of myocardial strain","volume":"58","author":"Gorcsan","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1152\/jappl.1993.75.1.389","article-title":"Increased afterload intensifies asynchronous wall motion and impairs ventricular relaxation","volume":"75","author":"Miura","year":"1993","journal-title":"J\u00a0Appl Physiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib20","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1016\/j.echo.2011.09.005","article-title":"Effects\u00a0of\u00a0aortic valve replacement on left ventricular dyssynchrony in aortic stenosis with narrow QRS complex","volume":"24","author":"Abe","year":"2011","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2015.02.009_bib21","first-page":"41","article-title":"Left\u00a0ventricular systolic asynchrony is induced even in the normal heart during increases in afterload: a study with angiotensin II stress pulsed tissue Doppler imaging","volume":"5","author":"Miyoshi","year":"2007","journal-title":"J\u00a0Echocardiogr"},{"key":"10.1016\/j.jcmg.2015.02.009_bib22","first-page":"H2833","article-title":"Stage-dependent changes in membrane currents in rats with monocrotaline-induced right ventricular hypertrophy","volume":"272","author":"Lee","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jcmg.2015.02.009_bib23","doi-asserted-by":"crossref","first-page":"343","DOI":"10.7326\/0003-4819-115-5-343","article-title":"Survival in patients with primary pulmonary hypertension","volume":"115","author":"D\u2019Alonzo","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcmg.2015.02.009_bib24","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1161\/CIRCULATIONAHA.109.898122","article-title":"Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL)","volume":"122","author":"Benza","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2015.02.009_bib25","doi-asserted-by":"crossref","first-page":"71","DOI":"10.7863\/jum.2011.30.1.71","article-title":"Speckle-tracking echocardiography\u2014a new technique for assessing myocardial function","volume":"30","author":"Mondillo","year":"2011","journal-title":"J\u00a0Ultrasound Med"}],"container-title":["JACC: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X15001849?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X15001849?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:42:07Z","timestamp":1761846127000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936878X15001849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1936878X15001849"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmg.2015.02.009","relation":{},"ISSN":["1936-878X"],"issn-type":[{"value":"1936-878X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Right Intraventricular Dyssynchrony in Idiopathic, Heritable, and Anorexigen-Induced Pulmonary Arterial Hypertension","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2015.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}