{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:18:44Z","timestamp":1791901124492,"version":"4.3.4"},"reference-count":170,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"vor","delay-in-days":367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Imaging"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.jcmg.2019.05.009","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T15:19:04Z","timestamp":1561994344000},"page":"1254-1278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"P1","title":["Controversies in Diagnostic Imaging of Patients With Suspected Stable and Acute Chest Pain Syndromes"],"prefix":"10.1016","volume":"12","author":[{"given":"Leslee J.","family":"Shaw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Blankstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanket S.","family":"Dhruva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela S.","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa S.S.","family":"Genders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond J.","family":"Gibbons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Greenwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Kwong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathon","family":"Leipsic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Mahmarian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Maron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eike","family":"Nagel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ed","family":"Nicol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen","family":"Nieman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia A.","family":"Pellikka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita F.","family":"Redberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Weir-McCall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Chandrasekhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmg.2019.05.009_bib1","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.ahj.2014.03.001","article-title":"Prevalence and predictors of nonobstructive coronary artery disease identified with coronary angiography in contemporary clinical practice","volume":"167","author":"Patel","year":"2014","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib2","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1056\/NEJMoa0907272","article-title":"Low diagnostic yield of elective coronary angiography","volume":"362","author":"Patel","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib3","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1056\/NEJM198005153022003","article-title":"The threshold approach to clinical decision making","volume":"302","author":"Pauker","year":"1980","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib4","doi-asserted-by":"crossref","first-page":"474","DOI":"10.7326\/M14-0027","article-title":"The optimal imaging strategy for patients\u00a0with\u00a0stable chest pain: a cost-effectiveness analysis","volume":"162","author":"Genders","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.7326\/0003-4819-152-3-201002020-00008","article-title":"Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging","volume":"152","author":"Schuetz","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib6","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jcmg.2016.12.010","article-title":"The quantitative science of evaluating imaging evidence","volume":"10","author":"Genders","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib7","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1016\/j.jacc.2014.07.017","volume":"64","author":"Fihn","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib8","first-page":"93","article-title":"Low diagnostic yield of\u00a0elective coronary angiography","volume":"363","author":"Diamond","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib9","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJM197906143002402","article-title":"Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease","volume":"300","author":"Diamond","year":"1979","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib10","doi-asserted-by":"crossref","first-page":"e3485","DOI":"10.1136\/bmj.e3485","article-title":"Prediction model to estimate presence of coronary artery disease: retrospective pooled analysis of existing cohorts","volume":"344","author":"Genders","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.jcmg.2019.05.009_bib11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jcmg.2017.02.020","article-title":"The external validity of prediction models for the diagnosis of obstructive coronary artery disease in patients with stable chest pain: insights from the PROMISE trial","volume":"11","author":"Genders","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib12","doi-asserted-by":"crossref","first-page":"e014467","DOI":"10.1136\/bmjopen-2016-014467","volume":"7","author":"Edlinger","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.jcmg.2019.05.009_bib13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1161\/CIRCULATIONAHA.116.023396","article-title":"European Society of Cardiology-recommended coronary artery disease consortium pretest probability scores more accurately predict obstructive coronary disease and cardiovascular events than the Diamond and Forrester score: The Partners Registry","volume":"134","author":"Bittencourt","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib14","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1001\/jamacardio.2016.5501","article-title":"Identification of patients with stable chest pain deriving minimal value from noninvasive testing: the PROMISE minimal-risk tool, a secondary analysis of a randomized clinical trial","volume":"2","author":"Fordyce","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12350-010-9320-5","article-title":"The role of radionuclide myocardial perfusion imaging for asymptomatic individuals","volume":"18","author":"Hendel","year":"2011","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib16","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1161\/01.CIR.93.11.1981","article-title":"Sex differences in myocardial infarction and coronary deaths in the Scottish MONICA Population of Glasgow 1985 to 1991. Presentation, diagnosis, treatment, and 28-day case fatality of 3991 events in men and 1551 events in women","volume":"93","author":"Tunstall-Pedoe","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib17","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1089\/jwh.2010.2595","article-title":"Signs and symptoms of suspected myocardial ischemia in women: results from the what is the optimal method for ischemia evaluation in women? Trial","volume":"20","author":"Mieres","year":"2011","journal-title":"J\u00a0Womens Health (Larchmt)"},{"key":"10.1016\/j.jcmg.2019.05.009_bib18","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/j.jacc.2009.02.013","volume":"53","author":"Hendel","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1745-6215-12-23","article-title":"Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening","volume":"12","author":"Li\u00e8vre","year":"2011","journal-title":"Trials"},{"key":"10.1016\/j.jcmg.2019.05.009_bib20","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1001\/jama.2009.476","article-title":"Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial","volume":"301","author":"Young","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib21","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1001\/jama.2014.15825","article-title":"Effect\u00a0of screening for coronary artery disease using CT angiography on mortality and cardiac events in high-risk patients with diabetes: the FACTOR-64 randomized clinical trial","volume":"312","author":"Muhlestein","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib22","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.jacc.2010.10.055","article-title":"Systematic review of guidelines on imaging of asymptomatic coronary artery disease","volume":"57","author":"Ferket","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib23","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1161\/CIRCIMAGING.113.000833","article-title":"Low yield of stress imaging in a population-based study of asymptomatic patients after percutaneous coronary intervention","volume":"7","author":"Peterson","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib24","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.jacc.2007.11.069","article-title":"Community-based provision of statin and aspirin after the detection of coronary artery calcium within a community-based screening cohort","volume":"51","author":"Taylor","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib25","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.jacc.2011.01.019","article-title":"Impact of coronary artery calcium scanning on coronary risk factors and downstream testing the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) prospective randomized trial","volume":"57","author":"Rozanski","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib26","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1016\/j.jacc.2011.10.851","volume":"58","author":"Villines","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib27","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1093\/ehjci\/jes060","article-title":"Meaning of zero coronary calcium score in symptomatic patients referred for coronary computed tomographic angiography","volume":"13","author":"Kim","year":"2012","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib28","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.jcmg.2012.06.006","article-title":"Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients","volume":"5","author":"Hou","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1148\/radiol.13122529","article-title":"Coronary artery calcium scoring to exclude flow-limiting coronary artery disease in symptomatic stable patients at low or intermediate risk","volume":"269","author":"Mouden","year":"2013","journal-title":"Radiology"},{"key":"10.1016\/j.jcmg.2019.05.009_bib30","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.atherosclerosis.2013.12.029","article-title":"Incremental prognostic value of coronary artery calcium score versus CT angiography among symptomatic patients without known coronary artery disease","volume":"233","author":"Hulten","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jcmg.2019.05.009_bib31","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.amjcard.2014.12.032","article-title":"Additive prognostic value of coronary artery calcium score over coronary computed tomographic angiography stenosis assessment in symptomatic patients without known coronary artery disease","volume":"115","author":"Chaikriangkrai","year":"2015","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib32","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.annemergmed.2010.01.017","article-title":"Coronary artery calcium scoring in the emergency department: identifying which patients with chest pain can be safely discharged home","volume":"56","author":"Nabi","year":"2010","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib33","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.annemergmed.2016.07.020","article-title":"Prognostic value of coronary artery calcium score in acute chest pain patients without known coronary artery disease: systematic review and meta-analysis","volume":"68","author":"Chaikriangkrai","year":"2016","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib34","doi-asserted-by":"crossref","first-page":"378","DOI":"10.2967\/jnumed.115.166595","article-title":"Optimizing evaluation of patients with low-to-intermediate-risk acute chest pain: a randomized study comparing stress myocardial perfusion tomography incorporating stress-only imaging versus cardiac CT","volume":"57","author":"Nabi","year":"2016","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib35","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/s12350-009-9159-9","article-title":"Diagnostic and clinical benefit of combined coronary calcium and\u00a0perfusion assessment in patients undergoing PET\/CT myocardial perfusion stress imaging","volume":"17","author":"Bybee","year":"2010","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib36","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1161\/CIRCULATIONAHA.107.717512","article-title":"Interrelation of coronary calcification, myocardial ischemia, and outcomes in patients with intermediate likelihood of coronary artery disease: a combined positron emission tomography\/computed tomography study","volume":"117","author":"Schenker","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib37","doi-asserted-by":"crossref","first-page":"e003966","DOI":"10.1161\/CIRCIMAGING.115.003966","article-title":"Prognostic value\u00a0of coronary artery calcium scoring in addition to single-photon emission computed tomographic myocardial perfusion imaging in symptomatic patients","volume":"9","author":"Engbers","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib38","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s12350-014-9958-5","article-title":"Combining stress-only myocardial perfusion imaging with coronary calcium scanning as a new paradigm for initial patient work-up: an exploratory analysis","volume":"22","author":"Uretsky","year":"2015","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib39","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.2967\/jnumed.114.153429","article-title":"Combined quantitative assessment of myocardial perfusion and coronary artery calcium score by hybrid 82Rb PET\/CT improves detection of coronary artery disease","volume":"56","author":"Brodov","year":"2015","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib40","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1016\/j.jacc.2012.07.012","volume":"60","author":"Fihn","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib41","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.jacc.2013.11.009","volume":"63","author":"Wolk","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib42","author":"UK NICE"},{"key":"10.1016\/j.jcmg.2019.05.009_bib43","first-page":"991","article-title":"Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: a meta-analysis","volume":"38","author":"Danad","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11883-018-0711-4","article-title":"Cardiorespiratory fitness and cardiovascular disease prevention: an update","volume":"20","author":"Al-Mallah","year":"2018","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.jcmg.2019.05.009_bib45","doi-asserted-by":"crossref","first-page":"k504","DOI":"10.1136\/bmj.k504","article-title":"Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials","volume":"360","author":"Siontis","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.jcmg.2019.05.009_bib46","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1056\/NEJMoa1415516","article-title":"Outcomes of anatomical versus functional testing for coronary artery disease","volume":"3712","author":"Douglas","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib47","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1161\/CIRCULATIONAHA.111.039255","volume":"124","author":"Cheng","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib48","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1001\/jamacardio.2016.5501","article-title":"Identifying stable chest pain patients deriving minimal value from noninvasive testing: The PROMISE \u201cMinimal Risk\u201d Tool","volume":"2","author":"Fordyce","year":"2017","journal-title":"JAMA Cardiology"},{"key":"10.1016\/j.jcmg.2019.05.009_bib49","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1016\/S0140-6736(15)60291-4","article-title":"CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial","volume":"385","year":"2015","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.jcmg.2019.05.009_bib50","article-title":"Changes in medical therapy and lifestyle after anatomical or functional testing for coronary artery disease","volume":"5","author":"Ladapo","year":"2016","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jcmg.2019.05.009_bib51","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1161\/CIRCULATIONAHA.111.029660","volume":"124","author":"Shaw","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib52","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1056\/NEJM199109193251204","article-title":"Prognostic value of a treadmill exercise score in outpatients with suspected coronary artery disease","volume":"325","author":"Mark","year":"1991","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib53","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jacc.2003.09.029","article-title":"Utility of myocardial perfusion imaging in patients with low-risk treadmill scores","volume":"43","author":"Poornima","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib54","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1161\/01.CIR.93.5.905","article-title":"Exercise myocardial perfusion SPECT in patients without known coronary artery disease: incremental prognostic value and use in risk stratification","volume":"93","author":"Hachamovitch","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib55","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1016\/j.jacc.2009.01.067","article-title":"Prediction of mortality and major cardiac events by exercise echocardiography in patients with normal exercise electrocardiographic testing","volume":"53","author":"Bouzas-Mosquera","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib56","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1001\/jamacardio.2017.1315","article-title":"Lesion-specific ischemia with noninvasive computed tomographic angiography: superior to conventional stress testing?","volume":"2","author":"Shaw","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib57","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.nuclcard.2006.12.324","article-title":"A\u00a0randomized trial of exercise treadmill ECG versus stress SPECT myocardial perfusion imaging as an initial diagnostic strategy in stable patients with chest pain and suspected CAD: cost analysis","volume":"14","author":"Sabharwal","year":"2007","journal-title":"J\u00a0Nuc Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib58","doi-asserted-by":"crossref","first-page":"e0193039","DOI":"10.1371\/journal.pone.0193039","article-title":"Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort","volume":"13","author":"Orini","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jcmg.2019.05.009_bib59","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0033-0620(89)90025-X","article-title":"The diagnostic accuracy of the exercise electrocardiogram: a meta-analysis of 22 years of research","volume":"32","author":"Detrano","year":"1989","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.jcmg.2019.05.009_bib60","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: The Task Force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"Montalescot","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib61","series-title":"Chest pain of recent onset: Assessment and diagnosis of recent onset chest pain or discomfort of suspected cardiac origin. CG95","year":"2010"},{"key":"10.1016\/j.jcmg.2019.05.009_bib62","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/j.semnuclmed.2004.09.004","article-title":"The role of myocardial perfusion imaging in special populations: women, diabetics and heart failure","volume":"35","author":"Mieres","year":"2005","journal-title":"Semin Nucl Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib63","doi-asserted-by":"crossref","first-page":"977","DOI":"10.7326\/0003-4819-135-11-200112040-00009","article-title":"Menstrual cyclic variation of myocardial ischaemia in premenopausal women with variant angina","volume":"35","author":"Kawano","year":"2001","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib64","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1161\/CIRCULATIONAHA.105.584524","article-title":"Stress testing in patients with diabetes mellitus: diagnostic and prognostic value","volume":"113","author":"Albers","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/S0735-1097(97)00091-0","article-title":"A\u00a0reappraisal of exercise electrocardiographic indexes of the severity of ischemic heart disease: angiographic and scintigraphic correlates","volume":"29","author":"Bogaty","year":"1997","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib66","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11936-017-0525-7","article-title":"Updates on stress imaging testing and myocardial viability with advanced imaging modalities","volume":"19","author":"Hedgire","year":"2017","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib68","series-title":"Update to chest pain of recent onset: assessment and diagnosis of recent onset chest pain or discomfort of suspected cardiac origin. CG95","year":"2016"},{"key":"10.1016\/j.jcmg.2019.05.009_bib69","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1161\/01.CIR.60.6.1300","article-title":"Exercise cross-sectional echocardiography in ischemic heart disease","volume":"60","author":"Wann","year":"1979","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib70","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.echo.2017.11.013","article-title":"Clinical applications of ultrasonic enhancing agents in echocardiography: 2018 American Society of Echocardiography Guidelines Update","volume":"31","author":"Porter","year":"2018","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2019.05.009_bib71","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0025-6196(11)64660-0","article-title":"Stress echocardiography. Part II. Dobutamine stress echocardiography: techniques, implementation, clinical applications, and correlations [see comments]","volume":"70","author":"Pellikka","year":"1995","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jcmg.2019.05.009_bib72","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.echo.2007.07.003","article-title":"American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography","volume":"20","author":"Pellikka","year":"2007","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2019.05.009_bib73","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0735-1097(97)00427-0","article-title":"Outcome after normal exercise echocardiography and predictors of subsequent cardiac events: follow-up of 1,325 patients","volume":"31","author":"McCully","year":"1998","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib74","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1161\/01.CIR.97.15.1474","article-title":"Role of dobutamine stress echocardiography in predicting outcome in 860 patients with known or suspected coronary artery disease","volume":"97","author":"Chuah","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib75","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0735-1097(01)01801-0","article-title":"Prognostic value of exercise echocardiography in 5,798 patients: is there a gender difference?","volume":"39","author":"Arruda-Olson","year":"2002","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib76","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/S0735-1097(00)01214-6","article-title":"Prognostic value of exercise echocardiography in 2,632 patients > or\u00a0= 65 years of age","volume":"37","author":"Arruda","year":"2001","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib77","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.echo.2009.11.023","article-title":"Characteristics and outcomes of patients with abnormal stress echocardiograms and angiographically mild coronary artery disease (<50% stenoses) or normal coronary arteries","volume":"23","author":"From","year":"2010","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2019.05.009_bib78","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.ahj.2005.06.023","volume":"151","author":"Ling","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib79","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","volume":"18","author":"Lang","year":"2005","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2019.05.009_bib80","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1161\/CIRCULATIONAHA.106.684357","article-title":"Investigating cardiac function using motion and deformation analysis in the setting of coronary artery disease","volume":"116","author":"Bijnens","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib81","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1001\/jama.2008.1022","article-title":"Left ventricular function and exercise capacity","volume":"301","author":"Grewal","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib82","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/S0735-1097(00)00586-6","article-title":"Assessment of cardiac risk before nonvascular surgery: dobutamine stress echocardiography in 530 patients","volume":"35","author":"Das","year":"2000","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib83","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.echo.2007.08.028","article-title":"Safety of stress echocardiography supervised by registered nurses: results of a 2-year audit of 15,404 patients","volume":"21","author":"Kane","year":"2008","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jcmg.2019.05.009_bib84","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.jacc.2010.11.002","article-title":"ACCF\/ASE\/AHA\/ASNC\/HFSA\/HRS\/SCAI\/SCCM\/SCCT\/SCMR 2011 Appropriate use criteria for echocardiography","volume":"57","author":"Douglas","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib85","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"Montalescot","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib86","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0140-6736(11)61335-4","article-title":"Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial","volume":"379","author":"Greenwood","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jcmg.2019.05.009_bib87","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/eurheartj\/ehs022","article-title":"MR-IMPACT II: Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary artery disease Trial: perfusion-cardiac magnetic resonance vs. single-photon emission computed tomography for the detection of coronary artery disease: a comparative","volume":"34","author":"Schwitter","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib88","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1532-429X-12-29","article-title":"Meta-analysis of the diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of coronary artery disease","volume":"12","author":"Hamon","year":"2010","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"key":"10.1016\/j.jcmg.2019.05.009_bib89","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.jacc.2011.12.040","volume":"59","author":"Jaarsma","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib90","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1001\/jama.2016.12680","article-title":"Effect of care guided by cardiovascular magnetic resonance, myocardial perfusion scintigraphy, or NICE guidelines on subsequent unnecessary angiography rates: the CE-MARC 2 randomized clinical trial","volume":"316","author":"Greenwood","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib91","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1532-429X-14-61","volume":"14","author":"Schwitter","year":"2012","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"key":"10.1016\/j.jcmg.2019.05.009_bib92","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1161\/CIRCULATIONAHA.112.000071","article-title":"Comparison of cardiovascular magnetic resonance and single-photon emission computed tomography in women with suspected coronary artery disease from the CE-MARC Trial","volume":"129","author":"Greenwood","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib93","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.jcmg.2014.07.011","article-title":"Diagnostic accuracy of myocardial magnetic resonance perfusion to diagnose ischemic stenosis with fractional flow reserve as reference: systematic review and meta-analysis","volume":"7","author":"Li","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib94","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.jacc.2007.06.030","article-title":"Diagnostic performance of stress cardiac magnetic resonance imaging in the detection of coronary artery disease: a meta-analysis","volume":"50","author":"Nandalur","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib95","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jacc.2013.03.080","article-title":"Prognostic value of stress cardiac magnetic resonance imaging in patients with known or suspected coronary artery disease: a systematic review and meta-analysis","volume":"62","author":"Lipinski","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib96","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1161\/CIRCULATIONAHA.109.907659","article-title":"Incremental prognostic significance of combined cardiac magnetic resonance imaging, adenosine stress perfusion, delayed enhancement, and left ventricular function over preimaging information for the prediction of adverse events","volume":"123","author":"Bingham","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib97","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1161\/CIRCULATIONAHA.106.652016","article-title":"Prognostic value of cardiac magnetic resonance stress tests: adenosine stress perfusion and dobutamine stress wall motion imaging","volume":"115","author":"Jahnke","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib98","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/M15-1801","article-title":"Prognostic value of cardiovascular magnetic resonance and single-photon emission computed tomography in suspected coronary heart disease: long-term follow-up of a prospective, diagnostic accuracy cohort study","volume":"165","author":"Greenwood","year":"2016","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib99","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1056\/NEJMoa0806576","article-title":"Diagnostic performance of coronary angiography by 64-row CT","volume":"359","author":"Miller","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib100","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.jacc.2011.02.074","volume":"58","author":"Min","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib101","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1093\/eurheartj\/eht293","article-title":"Prognostic value of coronary computed tomography angiography during 5 years of follow-up in patients with suspected coronary artery disease","volume":"34","author":"Hadamitzky","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib102","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/ehjci\/jex014","article-title":"Comparison of the prognostic value of negative non-invasive cardiac investigations in patients with suspected or known coronary artery disease-a meta-analysis","volume":"18","author":"Smulders","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib103","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jacc.2013.04.064","article-title":"Optimized prognostic score for coronary computed tomographic angiography: results from the CONFIRM registry (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter Registry)","volume":"62","author":"Hadamitzky","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib104","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1161\/CIRCULATIONAHA.116.024360","article-title":"Prognostic value of noninvasive cardiovascular testing in patients with stable chest pain: insights from the PROMISE trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain)","volume":"135","author":"Hoffmann","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib105","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.jacc.2016.02.026","article-title":"Use of coronary computed tomographic angiography to guide management of patients with coronary disease","volume":"67","author":"Williams","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib106","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1056\/NEJMoa1805971","article-title":"Coronary CT angiography and 5-year risk of myocardial infarction","volume":"379","author":"Newby","year":"2018","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib107","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.jacc.2006.01.041","article-title":"Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography","volume":"47","author":"Hoffmann","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib108","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jcmg.2012.03.019","article-title":"The napkin-ring sign indicates advanced atherosclerotic lesions in coronary CT angiography","volume":"5","author":"Maurovich-Horvat","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib109","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jacc.2007.03.044","article-title":"Multislice computed tomographic characteristics of coronary lesions in acute coronary syndromes","volume":"50","author":"Motoyama","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib110","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jacc.2015.05.069","article-title":"Plaque\u00a0characterization by coronary computed tomography angiography and the likelihood of acute coronary events in mid-term follow-up","volume":"66","author":"Motoyama","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib111","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/jamacardio.2017.4973","article-title":"Use of high-risk coronary atherosclerotic plaque detection for risk stratification of patients with stable chest pain","volume":"3","author":"Ferencik","year":"2018","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib112","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jacc.2018.10.066","article-title":"Coronary artery plaque characteristics associated with adverse outcomes in the SCOT-HEART Study","volume":"73","author":"Williams","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib113","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1016\/j.jacc.2009.11.096","article-title":"Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation","volume":"55","author":"Tonino","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib114","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1161\/01.CIR.0000072790.23090.41","article-title":"Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion SPECT","volume":"107","author":"Hachamovitch","year":"2003","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jcmg.2019.05.009_bib115","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.114.002666","article-title":"Diagnostic accuracy of stress myocardial perfusion imaging compared to invasive coronary angiography with fractional flow reserve meta-analysis","volume":"8","author":"Takx","year":"2015","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib116","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"Montalescot","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib117","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.jacc.2012.11.061","article-title":"Outcomes after coronary computed tomography angiography in the emergency department: a systematic review and meta-analysis of randomized, controlled trials","volume":"61","author":"Hulten","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib118","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1136\/hrt.2009.169441","article-title":"Computed tomography versus exercise electrocardiography in patients with stable chest complaints: real-world experiences from a fast-track chest pain clinic","volume":"95","author":"Nieman","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.jcmg.2019.05.009_bib119","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.media.2013.05.007","article-title":"Standardized evaluation framework for evaluating coronary artery stenosis detection, stenosis quantification and lumen segmentation algorithms in computed tomography angiography","volume":"17","author":"Kiri\u015fli","year":"2013","journal-title":"Med Image Anal"},{"key":"10.1016\/j.jcmg.2019.05.009_bib120","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1161\/CIRCULATIONAHA.109.915009","article-title":"Cardiac positron emission tomography\/computed tomography imaging accurately detects anatomically and functionally significant coronary artery disease","volume":"122","author":"Kajander","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib121","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1093\/ehjci\/jeu135","article-title":"Added value of hybrid myocardial perfusion SPECT and CT coronary angiography in the diagnosis of coronary artery disease","volume":"15","author":"Schaap","year":"2014","journal-title":"Eur Heart J Cardiovasc Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib122","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1001\/jama.2013.7834","article-title":"Prevalence and extent of obstructive coronary artery disease among patients undergoing elective coronary catheterization in New York State and Ontario","volume":"310","author":"Ko","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib123","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.mayocp.2016.11.016","article-title":"Prevalence and prognosis of nonobstructive coronary artery disease in patients undergoing coronary angiography or coronary computed tomography angiography: a meta-analysis","volume":"92","author":"Wang","year":"2017","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jcmg.2019.05.009_bib124","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1093\/eurheartj\/ehv444","article-title":"Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR CT\u202f: outcome and resource","volume":"36","author":"Douglas","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib125","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jacc.2016.05.057","article-title":"1-Year Outcomes of FFRCT-guided care in patients with suspected coronary disease: the PLATFORM study","volume":"68","author":"Douglas","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib126","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jcmg.2015.11.025","article-title":"Clinical use of coronary CTA\u2013derived FFR for decision-making in stable CAD","volume":"10","author":"N\u00f8rgaard","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib127","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/ehjci\/jex068","article-title":"Computed tomography derived fractional flow reserve testing in stable patients with typical angina pectoris: influence on downstream rate of invasive coronary angiography","volume":"19","author":"Jensen","year":"2018","journal-title":"Eur Hear J Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib128","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.jcmg.2016.11.024","article-title":"Noninvasive FFR derived from coronary CT angiography. Management and outcomes in the PROMISE trial","volume":"10","author":"Lu","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Img"},{"issue":"4 spec. iss.","key":"10.1016\/j.jcmg.2019.05.009_bib129","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.nuclcard.2007.05.008","article-title":"Underestimation of extent of ischemia by gated SPECT myocardial perfusion imaging in patients with left main coronary artery disease","volume":"14","author":"Berman","year":"2007","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.e6717","article-title":"Use of 3\u00d72 tables with an intention to diagnose approach to assess clinical performance of diagnostic tests: meta-analytical evaluation of coronary CT angiography studies","volume":"345","author":"Schuetz","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.jcmg.2019.05.009_bib131","first-page":"678","article-title":"Comparison of coronary CT angiography, SPECT, PET, and hybrid imaging for diagnosis of ischemic heart disease determined by fractional flow reserve","volume":"4","author":"Danad","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib132","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jacc.2013.11.043","article-title":"Diagnostic performance of non-invasive fractional flow reserve derived from coronary CT angiography in suspected coronary artery disease: the NXT trial (Analysis of Coronary Blood Flow Using CT Angiography: Next Steps)","volume":"63","author":"N\u00f8rgaard","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib133","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.clinimag.2016.05.005","article-title":"Potential impact of clinical use of noninvasive FFRCT on radiation dose exposure and downstream clinical event rate","volume":"40","author":"Bilbey","year":"2016","journal-title":"Clin Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib134","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/s10439-015-1436-y","article-title":"Comparison between non-invasive (coronary computed tomography angiography derived) and\u00a0invasive-fractional flow reserve in patients with serial stenoses within one coronary artery: a NXT Trial substudy","volume":"44","author":"Tanaka","year":"2016","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.jcmg.2019.05.009_bib135","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s10554-014-0420-1","article-title":"Prognostic value of coronary CT angiography on long-term follow-up of 6.9 years","volume":"30","author":"Dougoud","year":"2014","journal-title":"Int J Cardiovasc Imaging"},{"key":"10.1016\/j.jcmg.2019.05.009_bib136","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/j.jacc.2007.07.007","article-title":"64-slice computed tomography coronary angiography in patients with high, intermediate, or low pretest probability of significant coronary artery disease","volume":"50","author":"Meijboom","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib137","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.jacc.2009.06.014","article-title":"Adenosine-induced stress myocardial perfusion imaging using dual-source cardiac computed tomography","volume":"54","author":"Blankstein","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib138","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1093\/eurheartj\/eht488","article-title":"Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study","volume":"35","author":"Rochitte","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib139","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1001\/2012.jama.11274","article-title":"Diagnostic accuracy of fractional flow reserve from anatomic CT angiography","volume":"308","author":"Min","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jcmg.2019.05.009_bib140","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.jcmg.2017.10.010","article-title":"Comprehensive cardiac CT with myocardial perfusion imaging versus functional testing in suspected coronary artery disease: the multicenter, randomized CRESCENT-II trial","volume":"11","author":"Lubbers","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2019.05.009_bib141","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1056\/NEJMp0805920","article-title":"Pay now, benefits may follow--the case of cardiac computed tomographic angiography","volume":"359","author":"Redberg","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib142","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1161\/CIRCULATIONAHA.117.030578","article-title":"PROMISE Investigators. Prognostic value of coronary artery calcium in the PROMISE Study (Prospective Multicenter Imaging Study for Evaluation of Chest Pain)","volume":"136","author":"Budoff","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib143","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1093\/eurheartj\/ehv700","article-title":"Calcium imaging and selective computed tomography angiography in comparison to functional testing for suspected coronary artery disease: the multicentre, randomized CRESCENT trial","volume":"37","author":"Lubbers","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib144","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1161\/01.CIR.0000072790.23090.41","article-title":"Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography","volume":"107","author":"Hachamovitch","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib145","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJMoa070829","article-title":"Optimal medical therapy with or without PCI for stable coronary disease","volume":"356","author":"Boden","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib146","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1056\/NEJMoa0805796","article-title":"A\u00a0randomized trial of therapies for type 2 diabetes and coronary artery disease","volume":"360","author":"Frye","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib147","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1161\/CIRCULATIONAHA.107.743963","article-title":"Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy","volume":"117","author":"Shaw","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jcmg.2019.05.009_bib148","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1093\/eurheartj\/ehu278","volume":"35","author":"Windecker","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib149","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ahj.2012.05.018","article-title":"Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention","volume":"164","author":"Shaw","year":"2012","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib150","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jcin.2013.10.017","article-title":"Predicting outcome in the COURAGE trial (Clinical\u00a0Outcomes Utilizing Revascularization and Aggressive Drug Evaluation): coronary anatomy versus ischemia","volume":"7","author":"Mancini","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jcmg.2019.05.009_bib151","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s12350-012-9548-3","volume":"19","author":"Shaw","year":"2012","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib152","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa1205361","article-title":"Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease","volume":"367","author":"De Bruyne","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib153","doi-asserted-by":"crossref","first-page":"e004665","DOI":"10.1161\/CIRCOUTCOMES.118.004665","article-title":"\u2018Faith healing\u2019 and \u2018subtraction anxiety\u2019 in unblinded trials of procedures","volume":"11","author":"Rajkumar","year":"2018","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.jcmg.2019.05.009_bib154","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1056\/NEJMoa0807611","article-title":"Fractional flow reserve versus angiography for guiding percutaneous coronary intervention","volume":"360","author":"Tonino","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib155","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1001\/jamainternmed.2013.12855","article-title":"Percutaneous coronary intervention outcomes\u00a0in patients with stable obstructive coronary artery disease and myocardial ischemia: a collaborative meta-analysis of contemporary randomized clinical trials","volume":"174","author":"Stergiopoulos","year":"2014","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib156","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.jacc.2013.02.014","article-title":"Inducible\u00a0myocardial ischemia and outcomes in patients with coronary artery disease and left ventricular dysfunction","volume":"61","author":"Panza","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib157","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1056\/NEJMoa1602001","article-title":"Coronary-artery bypass surgery in patients with ischemic cardiomyopathy","volume":"374","author":"Velazquez","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib158","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ahj.2018.04.011","article-title":"International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: rationale and design","volume":"201","author":"Maron","year":"2018","journal-title":"Am Heart J"},{"key":"10.1016\/j.jcmg.2019.05.009_bib159","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1056\/NEJMe1206040","article-title":"Coronary CT angiography for acute chest pain","volume":"367","author":"Redberg","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib160","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1001\/jamainternmed.2017.2439","article-title":"Cardiac testing after emergency department evaluation for chest pain: time for a paradigm shift?","volume":"177","author":"Sun","year":"2017","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib161","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1016\/j.jacc.2012.07.013","volume":"60","author":"Fihn","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib162","first-page":"e139","article-title":"2014 AHA\/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"64","author":"Amsterdam","year":"2014"},{"key":"10.1016\/j.jcmg.2019.05.009_bib163","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/jamainternmed.2013.14407","article-title":"Hospital variation in the use of noninvasive cardiac imaging and its association with downstream testing, interventions, and outcomes","volume":"174","author":"Safavi","year":"2014","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib164","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.jacc.2012.11.056","article-title":"Temporal trends in the frequency of inducible myocardial ischemia during cardiac stress testing: 1991 to 2009","volume":"61","author":"Rozanski","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib165","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1001\/jamainternmed.2014.7657","article-title":"Comparative effectiveness of diagnostic testing strategies in emergency department patients with chest pain: an analysis of downstream testing, interventions, and outcomes","volume":"175","author":"Foy","year":"2015","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib166","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1001\/jamainternmed.2017.2432","article-title":"Cardiovascular testing and clinical outcomes in emergency department patients with chest pain","volume":"177","author":"Sandhu","year":"2017","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib167","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.amjcard.2017.12.030","article-title":"Utility of physician selection of cardiac tests in a chest pain unit to exclude acute coronary syndrome among patients without a history of coronary artery disease","volume":"121","author":"Howell","year":"2018","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib168","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/jamainternmed.2017.7519","article-title":"Acute chest pain in the emergency department","volume":"178","author":"Curfman","year":"2018","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jcmg.2019.05.009_bib169","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.acra.2016.07.011","article-title":"For the patient with \u201clow-risk chest pain\u201d-how low is low?","volume":"23","author":"Foy","year":"2016","journal-title":"Acad Radiol"},{"key":"10.1016\/j.jcmg.2019.05.009_bib170","first-page":"i6165","article-title":"Shared decision making in patients with low risk chest pain: prospective randomized pragmatic trial","volume":"355","author":"Hess","year":"2016","journal-title":"BMJ (Clin Res Ed)"},{"key":"10.1016\/j.jcmg.2019.05.009_bib171","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/acem.13355","article-title":"Impact of a shared decision making intervention on health care utilization: a secondary analysis of the Chest Pain Choice Multicenter Randomized Trial","volume":"25","author":"Schaffer","year":"2018","journal-title":"Acad Emerg Med"}],"container-title":["JACC: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X19304590?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X19304590?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:46:19Z","timestamp":1761846379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936878X19304590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":170,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S1936878X19304590"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmg.2019.05.009","relation":{},"ISSN":["1936-878X"],"issn-type":[{"value":"1936-878X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Controversies in Diagnostic Imaging of Patients With Suspected Stable and Acute Chest Pain Syndromes","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2019.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}