{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T07:10:12Z","timestamp":1787901012352,"version":"build-2784847793"},"reference-count":16,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Imaging"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.jcmg.2022.08.019","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T16:10:43Z","timestamp":1667837443000},"page":"1971-1973","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Fibroblast Activation"],"prefix":"10.1016","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1462-1185","authenticated-orcid":false,"given":"Sharmila","family":"Dorbala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmg.2022.08.019_bib1","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.jcmg.2019.07.015","article-title":"How to image cardiac amyloidosis: a practical approach","volume":"13","author":"Dorbala","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2022.08.019_bib2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1056\/NEJMoa2028631","article-title":"Daratumumab-based treatment for immunoglobulin light-chain amyloidosis","volume":"385","author":"Kastritis","year":"2021","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcmg.2022.08.019_bib3","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1161\/01.RES.0000126569.75419.74","article-title":"Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress","volume":"94","author":"Brenner","year":"2004","journal-title":"Circ Res"},{"key":"10.1016\/j.jcmg.2022.08.019_bib4","first-page":"358","article-title":"Coronary microvascular dysfunction is related to abnormalities in myocardial structure and function in cardiac amyloidosis","volume":"2","author":"Dorbala","year":"2014","journal-title":"J\u00a0Am Coll Cardiol HF"},{"key":"10.1016\/j.jcmg.2022.08.019_bib5","article-title":"Global fibroblast activation throughout the left ventricle but localized fibrosis after myocardial infarction","volume":"7","author":"Nagaraju","year":"2017","journal-title":"Scic Rep"},{"key":"10.1016\/j.jcmg.2022.08.019_bib6","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1172\/JCI74783","article-title":"Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis","volume":"124","author":"Moore-Morris","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jcmg.2022.08.019_bib7","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1016\/j.jcmg.2022.06.004","article-title":"Feasibility of\u00a068Ga-labeled fibroblast activation protein inhibitor PET\/CT in light-chain cardiac amyloidosis","volume":"15","author":"Wang","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcmg.2022.08.019_bib8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cardiores.2004.08.020","article-title":"Structural and functional characterisation of cardiac fibroblasts","volume":"65","author":"Camelliti","year":"2005","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jcmg.2022.08.019_bib9","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1161\/01.RES.0000089258.40661.0C","article-title":"Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin","volume":"93","author":"Gaudesius","year":"2003","journal-title":"Circ Res"},{"issue":"4","key":"10.1016\/j.jcmg.2022.08.019_bib10","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/FJC.0b013e3182116e39","article-title":"Fibroblasts and myofibroblasts: what are we talking about?","volume":"57","author":"Baum","year":"2011","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.jcmg.2022.08.019_bib11","first-page":"317","article-title":"Fibroblasts as sentinel cells: Synthesis of chemokines and regulation of inflammation","volume":"151","author":"Smith","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jcmg.2022.08.019_bib12","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1172\/JCI40295","article-title":"Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload","volume":"120","author":"Takeda","year":"2010","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jcmg.2022.08.019_bib13","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1091\/mbc.e11-05-0393","article-title":"The requirement for fibroblasts in angiogenesis: Fibroblast-derived matrix proteins are essential for endothelial cell lumen formation","volume":"22","author":"Newman","year":"2011","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.jcmg.2022.08.019_bib14","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.2967\/jnumed.118.210443","article-title":"Development of quinoline-based theranostic ligands for the targeting of fibroblast activation protein","volume":"59","author":"Lindner","year":"2018","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jcmg.2022.08.019_bib15","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.2967\/jnumed.121.263555","article-title":"Cardiac fibroblast activation in patients early after acute myocardial infarction: Integration with magnetic resonance tissue characterization and subsequent functional outcome","volume":"63","author":"Diekmann","year":"2022","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jcmg.2022.08.019_bib16","article-title":"Amyloid deposits and fibrosis on left ventricular endomyocardial biopsy correlate with extracellular volume in cardiac amyloidosis","volume":"10","author":"Pucci","year":"2021","journal-title":"J\u00a0Am Heart Assoc"}],"container-title":["JACC: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X22005484?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X22005484?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:54:17Z","timestamp":1761846857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936878X22005484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S1936878X22005484"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmg.2022.08.019","relation":{},"ISSN":["1936-878X"],"issn-type":[{"value":"1936-878X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fibroblast Activation","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2022.08.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2022.06.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}