{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T04:02:55Z","timestamp":1793937775193,"version":"4.8.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006041","name":"Innovate UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Cardiovascular Imaging"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.jcmg.2022.11.018","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T17:24:02Z","timestamp":1675877042000},"page":"800-816","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"title":["Deep-Learning for Epicardial Adipose Tissue Assessment With Computed\u00a0Tomography"],"prefix":"10.1016","volume":"16","author":[{"given":"Henry W.","family":"West","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Siddique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucrezia","family":"Volpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ria","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Lyasheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheena","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Dangas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos P.","family":"Kotanidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pete","family":"Tomlins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciara","family":"Mahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"Kardos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Adlam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Graby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan C.L.","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheerag","family":"Shirodaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Deanfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nehal N.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Neubauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith M.","family":"Channon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind Y.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward D.","family":"Nicol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charalambos","family":"Antoniades","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"37","key":"10.1016\/j.jcmg.2022.11.018_bib1","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.1093\/eurheartj\/ehab538","article-title":"Coronary CT angiography as an \u201cone-stop shop\u201d to detect the high-risk plaque and the vulnerable patient","volume":"42","author":"Antoniades","year":"2021","journal-title":"Eur Heart J"},{"issue":"3","key":"10.1016\/j.jcmg.2022.11.018_bib2","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"issue":"22","key":"10.1016\/j.jcmg.2022.11.018_bib3","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1016\/j.jacc.2021.07.053","article-title":"2021 AHA\/ACC\/ASE\/CHEST\/SAEM\/SCCT\/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"78","author":"Gulati","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.jcmg.2022.11.018_bib4","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1161\/ATVBAHA.119.312899","article-title":"Cardiac computed tomography: assessment of coronary inflammation and other plaque features","volume":"39","author":"Oikonomou","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.jcmg.2022.11.018_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41569-018-0097-6","article-title":"The role of adipose tissue in cardiovascular health and\u00a0disease","volume":"16","author":"Oikonomou","year":"2019","journal-title":"Nat Rev Cardiol"},{"issue":"13","key":"10.1016\/j.jcmg.2022.11.018_bib6","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1093\/cvr\/cvaa021","article-title":"Artificial intelligence in medical imaging: a radiomic guide to precision phenotyping of cardiovascular disease","volume":"116","author":"Oikonomou","year":"2020","journal-title":"Cardiovasc Res"},{"issue":"10","key":"10.1016\/j.jcmg.2022.11.018_bib7","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.jacc.2020.07.017","article-title":"Epicardial adipose tissue accumulation confers atrial conduction abnormality","volume":"76","author":"Nalliah","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"398","key":"10.1016\/j.jcmg.2022.11.018_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aal2658","article-title":"Detecting human coronary inflammation by imaging perivascular fat","volume":"9","author":"Antonopoulos","year":"2017","journal-title":"Sci Transl Med"},{"issue":"13","key":"10.1016\/j.jcmg.2022.11.018_bib10","first-page":"2677","article-title":"Standardized measurement of coronary inflammation using cardiovascular computed tomography: integration in clinical care as a prognostic medical device","volume":"117","author":"Oikonomou","year":"2021","journal-title":"Cardiovasc Res"},{"issue":"31","key":"10.1016\/j.jcmg.2022.11.018_bib11","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehac238","article-title":"Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease","volume":"43","author":"van Smeden","year":"2022","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.jcmg.2022.11.018_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03150-w","article-title":"Artificial intelligence based automatic quantification of epicardial adipose tissue suitable for large scale population studies","volume":"11","author":"Molnar","year":"2021","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.jcmg.2022.11.018_bib13","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s00330-013-3052-2","article-title":"Automated quantification of epicardial adipose tissue using CT angiography: evaluation of a prototype software","volume":"24","author":"Spearman","year":"2014","journal-title":"Eur Radiol"},{"issue":"6","key":"10.1016\/j.jcmg.2022.11.018_bib14","doi-asserted-by":"crossref","DOI":"10.1148\/ryai.2019190045","article-title":"Fully automated CT quantification of epicardial adipose tissue by deep learning: a multicenter study","volume":"1","author":"Commandeur","year":"2019","journal-title":"Radiol Artif Intell"},{"issue":"1","key":"10.1016\/j.jcmg.2022.11.018_bib15","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jcct.2017.11.007","article-title":"Epicardial adipose tissue density and volume are related to subclinical atherosclerosis, inflammation and major adverse cardiac events in asymptomatic subjects","volume":"12","author":"Goeller","year":"2018","journal-title":"J\u00a0Cardiovasc Comput Tomogr"},{"issue":"2","key":"10.1016\/j.jcmg.2022.11.018_bib16","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.atherosclerosis.2011.07.093","article-title":"Increase in epicardial fat volume is associated with greater coronary artery calcification progression in subjects at intermediate risk by coronary calcium score: a serial study using non-contrast cardiac CT","volume":"218","author":"Nakanishi","year":"2011","journal-title":"Atherosclerosis"},{"issue":"9","key":"10.1016\/j.jcmg.2022.11.018_bib17","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1093\/cvr\/cvx116","article-title":"\u201cDysfunctional\u201d adipose tissue in cardiovascular disease: a reprogrammable target or an innocent bystander?","volume":"113","author":"Antoniades","year":"2017","journal-title":"Cardiovasc Res"},{"issue":"5","key":"10.1016\/j.jcmg.2022.11.018_bib18","first-page":"640","article-title":"Atrial myopathy","volume":"4","author":"Shen","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Basic Trans Sci"}],"container-title":["JACC: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X22007227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936878X22007227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:54:02Z","timestamp":1761846842000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936878X22007227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S1936878X22007227"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmg.2022.11.018","relation":{},"ISSN":["1936-878X"],"issn-type":[{"value":"1936-878X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deep-Learning for Epicardial Adipose Tissue Assessment With Computed\u00a0Tomography","name":"articletitle","label":"Article Title"},{"value":"JACC: Cardiovascular Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmg.2022.11.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}