{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T01:24:46Z","timestamp":1792891486199,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T00:00:00Z","timestamp":1449532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cmghjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.jcmgh.2015.11.010","type":"journal-article","created":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T17:01:10Z","timestamp":1451322070000},"page":"189-209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["GATA4 Regulates Epithelial Cell Proliferation to Control Intestinal\u00a0Growth and Development in Mice"],"prefix":"10.1016","volume":"2","author":[{"given":"Bridget M.","family":"Kohlnhofer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cayla A.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily M.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele A.","family":"Battle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcmgh.2015.11.010_bib1","series-title":"Translational gastroenterology: organogenesis to disease","first-page":"85","article-title":"Basic science of small intestinal development","author":"Thompson","year":"2014"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.siny.2011.02.001","article-title":"Neonatal short bowel syndrome","volume":"16","author":"Gutierrez","year":"2011","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib3","series-title":"Translational gastroenterology: organogenesis to disease","first-page":"99","article-title":"Clincal small intestine","author":"Helmrath","year":"2014"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib4","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1242\/dev.065789","article-title":"Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis","volume":"138","author":"Grosse","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.tcb.2012.11.001","article-title":"Mechanisms controlling arrangements and movements of nuclei in pseudostratified epithelia","volume":"23","author":"Lee","year":"2013","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib6","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ydbio.2012.06.007","article-title":"Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice","volume":"369","author":"Bakker","year":"2012","journal-title":"Dev Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ydbio.2008.11.020","article-title":"Wnt5a is essential for intestinal elongation in mice","volume":"326","author":"Cervantes","year":"2009","journal-title":"Dev Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib8","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.devcel.2009.02.010","article-title":"Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2","volume":"16","author":"Gao","year":"2009","journal-title":"Dev Cell"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib9","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1242\/dev.020453","article-title":"Fgf9 signaling regulates small intestinal elongation and mesenchymal development","volume":"135","author":"Geske","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib10","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1242\/dev.044586","article-title":"Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract","volume":"137","author":"Mao","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib11","doi-asserted-by":"crossref","first-page":"e1000427","DOI":"10.1371\/journal.pgen.1000427","article-title":"Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium","volume":"5","author":"Matsuyama","year":"2009","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib12","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1002\/dvdy.22212","article-title":"Ror2 is required for midgut elongation during mouse development","volume":"239","author":"Yamada","year":"2010","journal-title":"Dev Dyn"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib13","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1186\/1756-0500-7-902","article-title":"Characterization of the developing small intestine in the absence of either GATA4 or GATA6","volume":"7","author":"Walker","year":"2014","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1471-213X-7-37","article-title":"Development of the mammalian liver and ventral pancreas is dependent on GATA4","volume":"7","author":"Watt","year":"2007","journal-title":"BMC Dev Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib15","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.cell.2004.07.024","article-title":"Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities","volume":"118","author":"Harfe","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib16","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s11248-005-7220-2","article-title":"A\u00a0generic tool for biotinylation of tagged proteins in transgenic mice","volume":"14","author":"Driegen","year":"2005","journal-title":"Transgenic Res"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1101\/gad.173930.111","article-title":"PRC2 directly methylates GATA4 and represses its transcriptional activity","volume":"26","author":"He","year":"2012","journal-title":"Genes Dev"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib18","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1101\/gad.11.8.1061","article-title":"Requirement of the transcription factor GATA4 for heart tube formation\u00a0and ventral morphogenesis","volume":"11","author":"Molkentin","year":"1997","journal-title":"Genes Dev"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib19","doi-asserted-by":"crossref","first-page":"12573","DOI":"10.1073\/pnas.0400752101","article-title":"GATA4 is essential for formation of the proepicardium and regulates cardiogenesis","volume":"101","author":"Watt","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ydbio.2012.06.005","article-title":"E-cadherin is required for intestinal morphogenesis in the mouse","volume":"371","author":"Bondow","year":"2012","journal-title":"Dev Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib21","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.bbagrm.2014.05.018","article-title":"GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27","volume":"1839","author":"Aronson","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/0471142727.mb2120s92","article-title":"Genome-wide location analysis by pull down of in\u00a0vivo biotinylated transcription factors","author":"He","year":"2010","journal-title":"Curr Protoc Mol Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib23","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.ydbio.2014.05.017","article-title":"GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development","volume":"392","author":"Walker","year":"2014","journal-title":"Dev Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib24","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1073\/pnas.0510839103","article-title":"Dicer function is essential for lung epithelium morphogenesis","volume":"103","author":"Harris","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib25","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1053\/j.gastro.2008.07.074","article-title":"GATA4 is essential for jejunal function in mice","volume":"135","author":"Battle","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib26","doi-asserted-by":"crossref","first-page":"5420","DOI":"10.1128\/MCB.00717-08","article-title":"GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is\u00a0required for cardiomyocyte proliferation in anterior heart field-derived myocardium","volume":"28","author":"Rojas","year":"2008","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0968-0004(00)89005-2","article-title":"D-type cyclins","volume":"20","author":"Sherr","year":"1995","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1242\/dev.128.1.25","article-title":"Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis","volume":"128","author":"Ishikawa","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/ncb1240","article-title":"Wnt signalling induces maturation of Paneth cells in intestinal crypts","volume":"7","author":"van Es","year":"2005","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib30","doi-asserted-by":"crossref","first-page":"3457","DOI":"10.1242\/dev.127.16.3457","article-title":"Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis","volume":"127","author":"Karlsson","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib31","doi-asserted-by":"crossref","first-page":"15817","DOI":"10.1073\/pnas.1205669109","article-title":"Hedgehog-responsive mesenchymal clusters direct patterning and emergence of intestinal villi","volume":"109","author":"Walton","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib32","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/ncomms1463","article-title":"Blimp1 regulates the transition of neonatal to adult intestinal epithelium","volume":"2","author":"Muncan","year":"2011","journal-title":"Nat Commun"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib33","doi-asserted-by":"crossref","first-page":"9060","DOI":"10.1128\/MCB.00124-06","article-title":"Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine","volume":"26","author":"Bosse","year":"2006","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib34","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1242\/dev.070763","article-title":"Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells","volume":"139","author":"VanDussen","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib35","doi-asserted-by":"crossref","first-page":"e105477","DOI":"10.1371\/journal.pone.0105477","article-title":"Characterization of platelet-derived growth factor-A expression in mouse tissues using a lacZ knock-in approach","volume":"9","author":"Andrae","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib36","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1053\/j.gastro.2011.01.033","article-title":"GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice","volume":"140","author":"Beuling","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib37","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1074\/jbc.M114.620211","article-title":"Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2","volume":"290","author":"San Roman","year":"2015","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jcmgh.2015.11.010_bib38","doi-asserted-by":"crossref","first-page":"e24484","DOI":"10.1371\/journal.pone.0024484","article-title":"Delta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell system","volume":"6","author":"Stamataki","year":"2011","journal-title":"PLoS One"}],"container-title":["Cellular and Molecular Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X15001939?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352345X15001939?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T21:32:39Z","timestamp":1653946359000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352345X15001939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S2352345X15001939"],"URL":"https:\/\/doi.org\/10.1016\/j.jcmgh.2015.11.010","relation":{},"ISSN":["2352-345X"],"issn-type":[{"value":"2352-345X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GATA4 Regulates Epithelial Cell Proliferation to Control Intestinal\u00a0Growth and Development in Mice","name":"articletitle","label":"Article Title"},{"value":"Cellular and Molecular Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcmgh.2015.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}